Cver016792.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cheilosia vernalis
Gene Symbol
-
Assembly
GCA_949126925.1
Location
OX421360.1:23281476-23282984[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.0043 0.54 11.6 3.2 1 23 223 245 223 245 0.98
2 9 1.1e-06 0.00013 23.0 1.5 1 23 251 274 251 274 0.94
3 9 0.00012 0.015 16.5 3.2 1 23 281 306 281 306 0.94
4 9 5.7e-06 0.00072 20.7 0.5 1 23 316 338 316 338 0.97
5 9 3.7e-06 0.00047 21.3 1.3 1 23 345 367 345 367 0.99
6 9 6e-05 0.0075 17.5 0.5 1 23 373 395 373 395 0.97
7 9 0.001 0.13 13.6 0.0 2 23 402 424 401 424 0.95
8 9 3.5e-05 0.0045 18.2 3.4 1 23 430 452 430 452 0.98
9 9 7.8e-06 0.00099 20.2 0.6 1 23 458 480 458 480 0.98

Sequence Information

Coding Sequence
atgactGTAACATTAGAGAATATGAACTCGTACTGTCGCACTTGTCTAAATGAACTAGAACCTGGTGCTGAATTACATATTCACGATACTCCCAACATAGCCAAATGGCTTGTAGTGTGCACGTCTCTGGACTTTGAGAAAAATGATGGGTATCCGAGTAGCATTTGTCAAAGTTGCTATTCTAAAATCCAAACTTCGTATGAGTTTCGTGTGATGTGTATTAAATCAATGCGAGAACTAGATGGTTTGATGAATGCCTTTCCAAAGCTAGAAATCGATAGACTTGAGTTGGAAGGCGCATCGGaagatttaaaaagttttcattgGCTTCAGCTAGCAAACCTGGAGGCCTACGATAGTACCACTACTGATAACAAGAACGAGATAATTACCCAATTGGTCGATGTGAAAAATGTTAAACCTAACCCAACTAGCGTCGCTCCAGATGCAGCACTTGATGAGCAAGAAATCGACCATAACGATGTATTCAGTGGTTTGGTCGATGATACTTCGGATTATGATTCACCAGCACCTGAGGAGAATATATTGGAAGGTGTTGAGGAGacggcaaaaaagaaaaacgagaaACCCCCACCACCGAAACGCGGCAGAAAACCAAAGGATGAAGACTATTCAATGCCAGCATACATAAAGACTCCAGAAATATACAACTGCGAAAAATGTCGAAAGAAATTCTTTAAAAAGGAACGTTTTGATGCCCACATTCGCCTACATGATGGGCTTAAGCCATACCCATGCAAGCTGTGTGACAAATCCTATAACAAGTCCTCTCACTTAAAGGTTCACATGCTAGATGTTCACACCGAACACAAGGAGGAGTACAAATGCGAGTATGACGGATGTGATAAAGTTTTCCGTCGTAAACAAACACTTCGGGTCCACTGTCGCATAAAACACTCCGAAGTCAAGTACGAACCGAAAATTTTCATATGTGAGGAATGTGGCAAGACTTTCCGGAACATTGGGGCTCTAAGGGATCATCGGTTCAAACATACTGGCGAAGAGTTTCCCTACAAATGTGAACAGTGCGGTAAAGGTTATGTTTCGCAGCGCACATACCGTGACCATATGATGCGGCACGCGGGAATTAAGAATTTCGTTTGTCCCTACTGTGGCTtgagaaaaacaacaaagagCGAACTACGTATCCACATCAACTACCACACTAAGGAAAAACAATGGCCATGCCCGTCATGTCCGCAGGTTTTCAACAGTTCTGCTAATCTCGGTCTACACAACCGTGTCGTCCACAAGGGTATTCGACGATTTAAGTGCAAGTACTGCGATCAGAGCTTTGGCAAAGCGGAGACGCTCAAGCATCATGAAATGCGTCACACAGGTGAAAAACCACATGAATGCACAATCTGCGAAAAGAGATTCATTCAAGTAGTCGCATTGCGGGCCCATCTGAAAACTCACAATAAAGCAACTTAA
Protein Sequence
MTVTLENMNSYCRTCLNELEPGAELHIHDTPNIAKWLVVCTSLDFEKNDGYPSSICQSCYSKIQTSYEFRVMCIKSMRELDGLMNAFPKLEIDRLELEGASEDLKSFHWLQLANLEAYDSTTTDNKNEIITQLVDVKNVKPNPTSVAPDAALDEQEIDHNDVFSGLVDDTSDYDSPAPEENILEGVEETAKKKNEKPPPPKRGRKPKDEDYSMPAYIKTPEIYNCEKCRKKFFKKERFDAHIRLHDGLKPYPCKLCDKSYNKSSHLKVHMLDVHTEHKEEYKCEYDGCDKVFRRKQTLRVHCRIKHSEVKYEPKIFICEECGKTFRNIGALRDHRFKHTGEEFPYKCEQCGKGYVSQRTYRDHMMRHAGIKNFVCPYCGLRKTTKSELRIHINYHTKEKQWPCPSCPQVFNSSANLGLHNRVVHKGIRRFKCKYCDQSFGKAETLKHHEMRHTGEKPHECTICEKRFIQVVALRAHLKTHNKAT