Basic Information

Insect: Cheilosia variabilis
Gene Symbol: ush
Assembly: GCA_951230905.1
Location: OX579680.1:26901572-26910277[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.012 1.7 10.1 0.0 1 20 211 230 211 232 0.90

2 9 0.00024 0.033 15.4 0.8 1 23 277 299 277 299 0.98

3 9 0.025 3.6 9.1 1.0 2 21 324 343 324 344 0.92

4 9 0.041 5.8 8.4 2.9 2 21 696 715 695 716 0.93

5 9 0.0074 1 10.7 0.0 3 21 753 771 751 772 0.92

6 9 1.4 1.9e+02 3.6 0.1 1 23 818 840 818 840 0.71

7 9 0.012 1.7 10.1 1.3 1 23 846 868 846 868 0.99

8 9 0.00016 0.022 16.0 0.6 1 23 938 961 938 961 0.96

9 9 0.27 38 5.8 0.8 2 20 1088 1106 1087 1108 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.012	1.7	10.1	0.0	1	20	211	230	211	232	0.90
2	9	0.00024	0.033	15.4	0.8	1	23	277	299	277	299	0.98
3	9	0.025	3.6	9.1	1.0	2	21	324	343	324	344	0.92
4	9	0.041	5.8	8.4	2.9	2	21	696	715	695	716	0.93
5	9	0.0074	1	10.7	0.0	3	21	753	771	751	772	0.92
6	9	1.4	1.9e+02	3.6	0.1	1	23	818	840	818	840	0.71
7	9	0.012	1.7	10.1	1.3	1	23	846	868	846	868	0.99
8	9	0.00016	0.022	16.0	0.6	1	23	938	961	938	961	0.96
9	9	0.27	38	5.8	0.8	2	20	1088	1106	1087	1108	0.92

Sequence Information

Coding Sequence: ATGCCACCTTTAATTCTGCATCTGCAGAAGGCACGAGAGCACGAGCATGCCATCGACTCCGGGTCTGGGACTGCAGTAGGAGCAGTGTTTCAGCAAGACGAACGACATTCGAGCAACATTGCCGAACACGAAACAAAAGATCTAAGCCCTAGCGATTTGAATGAGCAAGCCGATGCGGTTTCGTCGGCGGACATAGATCAGTCGGCTGAACCGCGAACTCCGTTCACAACGGAATCCCTGATGGCGGAGAACCGCCCATCGTCGAGTACGCCCCGAACACTATCACCGCCCTCGGATCCGGAAGTTGATGACCATCATCGTTCACCTTCGGTCCGATCGGATATACAGTCGGCGACGAACTCACCCTCCGAGCATGAAGATTCACCAATAGTTCCTGCTGCTGCCGTTATTGCTGCCATTCCTAAGCTGCGCCTAAATGCACTTCTAGCTTCTGATCCCGCCCTAAATCCAGATgcgagaaatttgaaaattctccACGAGGAGTCCACCAATAATCATCACCACGAGGAAGCCGGTGTGACCCCCACTCCAGTCGTCGTCGATCAGAAGTCGTCGGCGAAAACCCAAACGTCAGCTGTTGTCGTCGATAATGCGCAGCGTGTCAAAGTGTTTATGTGTCTTCCCTGTGGCATTGGATTCTCGTCGAGGTCGACACTGGAAGCACATCAGGCGTACTATTGTTCCCACAGaAAAGAAACTGAAGAGGATCCAGCTGGAGGGGGTGGCGGAAGCGCCACGTCTGGTGATAAGAATTCCACTGCTACATCCGGTGAGCCATCAGCGAAATCTATTAAGACTGGCAAGCAATACGCTTGCACACAGTGCTCCTACAGCGCCGATAAGAAGGTCTCGTTAAATCGTCACATGCGTATGCACCAAAGCTCACCGGCGCCCAGTTCGAACGCCTCGAATGGTGGCGATGACAGTTCTAGTCAACAAATCGATCGTTACTGCTCTGAATGTGATATTAGATTCTCGAATGTTAAAACGTATCGGGCTCATAAGCAACACTATTGTAGTTCCAGACGCAATGATGGCCAAACGACACCAAAACTACCGGAGCCAAGCTTGAAAACTAGTGGCGGTTCCGTGAGTCCACCGCAGGCGCGAACGAAAACGCCCACACCAGCTGCAGTTGTTGCAGCTGCCGCGGCAGCAGCAGCCGCCGTCACTCCCCAACCATTCATAGCTCTACCTACGAATCCCATTCTTATTATTCCATATTATCTGATACGAGCGGCCAGCATGATACCGGGACCATTAACATCGGTATCGTCTGGCATTGCGAATCCCGAAAGCACATGTTTCTCACTAGAAAACGGATCTCTTAAGCCTATGGCGACCGCCTTAAGCACCAGCACCATTACGAACATTACTGCACGAACACATCCTCCACCGGCACGTACTCCATCGAATAATAATGATACGGCAACACCACTGCTAACGGAGAAAAATGCACGCACAGCGTCTGCAAATAGCTGCAGTGATTCCGCGAAGCAAAGCAAAAAGGACGGCCCTAGGGACTTTGCACCGCTGGACCTGTCACTGCGTCGTTCTCCCATTCAAAGCTCGCAACGTGTCCGCTCATCGTCCAGTTTCATGCAACCTGCAGATGAACGAATCGATATCGAAACGATGATGGAGGGCAAGGAGAATCTTTCCATCGACAGTGGTAGCATGACACCCGAGCAAATCGTTTGTGCTCCATCTTTACCCAATAGTCCTTCCATGAGTCCATCGCCGAAGCGTCGCACCCTCAGTCCACGAAGTAGCAGTGCGGCTTCCATGTCGCCTGTGCCGCCATCTGTCATGGATCACCTGCCGCTGCGATCGATTTTACCCGCTGAAATCGCCATGAAACTGACTGAGTCGAATATAATTCCACCACTGATCGCGAAACAGAATCTAGAGCTGGCCTTTAAGTTGTCTTCGGCGAACAGTAAACAAGGGGATTCGGCCAAGGCCGCAATGAGCAATCCACTATTGGGCTTGTCTGGTACGCCCATGAATGTGGGAGCAGCAACCAGCGGACAGCCACAGATTTTCGTCAAGCAGGGCGTGTCCAAGTGCAAGGAATGCAACATCGTCTTCTGCAAGTACGAGAACTACTTGGCCCACAAACAGCACTACTGTTCGGCTCGAAATCAAGAAGATACCGAAAGCAAGATCAGTACTCCTCCATCGGCGTCGAATTCCGGTGTGGATACCAATCCTATTGCCTATCAGCAGTTAATTTGCGCAGCCTGTGGCATCAAGTACACTTCGCTGGATAACCTGCGAGCCCATCAGAAGTTCTACTGTCCCAAGGGAGGTGGTGACGCCGCCGCTGCACCACCAGTCACTAAGGAGAAGTGTGGAAAGTGTAAAACGATTCATGAAATCGGACAGCCCTGCCCGCCAATTGCTGCAACCGCTGCGCAACAAAGTTCCTACAAGTGTCCTGTTTGCGATGTCATCAGTCTTACGGCTGCTGAGAGTCGCAAGCATTTGGAGACGCATAGCAGCGTCAAGGCATTCCGCTGTTCCATTTGTCGATACAAAGGAAACACTTTGCGtGGCATGAGGACacacattcggatgcatttcgACAAGAAGACTTCAGACTTTAACGAGGAGAACTACATGTCGTGCATTCTGGAAGACGACGGCCTGGAAATTCCTAGTCCGGCGTCCCTTAATCAGGAGCAGGTCTCGCAATTCGCCACACAACAGATTCTTCTgcatcagcaacaacaacaacaacagtcgGCAACACAACAACAGCATTCGCCACAGCAACCGCAACAGATATTCAACTGCGAGATTTGCAACTACTCATCATCCTACAAGGGCAATGTGATGCGCCACATGAAACTAGTTCACTCTCAAACCGGCACATCGCCTTCCATTTCACCCGAGATGATGATGGAAGAGGGTGAGCCCACCACTCACAGTCTAAACGGAGACAATGGCAGCAGTCTTCCCGAAGGTTTCACCATCAAAACGGAACCATTAGAAGCAGTTACCGCCGCCGCTACGAAGAACAATAACAATTCGACTCCCAACCATCACCTGGAGACACTTGCACAGATCAAATTAGAACCAATGGAGCTCGCAGACGGCGTTATTCGAGCTCTTCCTTCGCCCCTTTCAGCCCCACCACCACCGCTTAACTCATCATCACCCCTGTCTGGCGATGAGAACTCATTGCTGAGGAACTCTACTTCGATTGGGTCCAGCGGACTGCCCTTCAATCAGAAGTACTGTCAGACTTGTGACATTAGTTTCAACTACATGAAGACCTTCCTAGCGCATAAGCAGTTCTATTGCAAGAATAAAACTCGAACAGATGCGGATAGCCCGAGTCCGGTGCCGCCAGTGCAATCGCCTACAATGCTGAATAAGAATAAGGAGAACTTGGAAGCGGCCATGTTATAG
Protein Sequence: MPPLILHLQKAREHEHAIDSGSGTAVGAVFQQDERHSSNIAEHETKDLSPSDLNEQADAVSSADIDQSAEPRTPFTTESLMAENRPSSSTPRTLSPPSDPEVDDHHRSPSVRSDIQSATNSPSEHEDSPIVPAAAVIAAIPKLRLNALLASDPALNPDARNLKILHEESTNNHHHEEAGVTPTPVVVDQKSSAKTQTSAVVVDNAQRVKVFMCLPCGIGFSSRSTLEAHQAYYCSHRKETEEDPAGGGGGSATSGDKNSTATSGEPSAKSIKTGKQYACTQCSYSADKKVSLNRHMRMHQSSPAPSSNASNGGDDSSSQQIDRYCSECDIRFSNVKTYRAHKQHYCSSRRNDGQTTPKLPEPSLKTSGGSVSPPQARTKTPTPAAVVAAAAAAAAAVTPQPFIALPTNPILIIPYYLIRAASMIPGPLTSVSSGIANPESTCFSLENGSLKPMATALSTSTITNITARTHPPPARTPSNNNDTATPLLTEKNARTASANSCSDSAKQSKKDGPRDFAPLDLSLRRSPIQSSQRVRSSSSFMQPADERIDIETMMEGKENLSIDSGSMTPEQIVCAPSLPNSPSMSPSPKRRTLSPRSSSAASMSPVPPSVMDHLPLRSILPAEIAMKLTESNIIPPLIAKQNLELAFKLSSANSKQGDSAKAAMSNPLLGLSGTPMNVGAATSGQPQIFVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEDTESKISTPPSASNSGVDTNPIAYQQLICAACGIKYTSLDNLRAHQKFYCPKGGGDAAAAPPVTKEKCGKCKTIHEIGQPCPPIAATAAQQSSYKCPVCDVISLTAAESRKHLETHSSVKAFRCSICRYKGNTLRGMRTHIRMHFDKKTSDFNEENYMSCILEDDGLEIPSPASLNQEQVSQFATQQILLHQQQQQQQSATQQQHSPQQPQQIFNCEICNYSSSYKGNVMRHMKLVHSQTGTSPSISPEMMMEEGEPTTHSLNGDNGSSLPEGFTIKTEPLEAVTAAATKNNNNSTPNHHLETLAQIKLEPMELADGVIRALPSPLSAPPPPLNSSSPLSGDENSLLRNSTSIGSSGLPFNQKYCQTCDISFNYMKTFLAHKQFYCKNKTRTDADSPSPVPPVQSPTMLNKNKENLEAAML

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01223805;
90% Identity: iTF_00316349;
80% Identity: -