Basic Information

Insect: Cheilosia variabilis
Gene Symbol: L
Assembly: GCA_951230905.1
Location: OX579680.1:46881889-46900149[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 4.7e-06 0.00066 20.8 1.7 1 23 217 239 217 239 0.98

2 15 0.39 55 5.3 5.8 1 23 245 267 245 267 0.98

3 15 2e-07 2.9e-05 25.1 3.1 1 23 273 295 273 295 0.99

4 15 9.4e-06 0.0013 19.9 0.3 1 23 301 323 301 323 0.98

5 15 0.0035 0.49 11.8 0.4 2 23 426 448 425 448 0.97

6 15 0.017 2.4 9.6 1.4 1 23 529 551 529 551 0.97

7 15 0.00093 0.13 13.6 1.0 2 23 559 580 558 580 0.95

8 15 8.8e-05 0.012 16.8 0.6 1 23 588 613 588 613 0.93

9 15 0.0012 0.17 13.2 2.9 1 23 705 727 705 728 0.96

10 15 0.00089 0.13 13.6 4.6 2 23 910 932 909 932 0.96

11 15 0.1 15 7.1 0.1 1 23 938 960 938 960 0.92

12 15 8.4 1.2e+03 1.1 0.5 2 23 968 989 968 989 0.93

13 15 9.8 1.4e+03 0.9 0.4 2 23 1078 1099 1078 1099 0.91

14 15 0.017 2.4 9.6 0.0 1 23 1109 1131 1109 1131 0.95

15 15 1.5 2.1e+02 3.5 1.2 1 23 1138 1160 1138 1160 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	4.7e-06	0.00066	20.8	1.7	1	23	217	239	217	239	0.98
2	15	0.39	55	5.3	5.8	1	23	245	267	245	267	0.98
3	15	2e-07	2.9e-05	25.1	3.1	1	23	273	295	273	295	0.99
4	15	9.4e-06	0.0013	19.9	0.3	1	23	301	323	301	323	0.98
5	15	0.0035	0.49	11.8	0.4	2	23	426	448	425	448	0.97
6	15	0.017	2.4	9.6	1.4	1	23	529	551	529	551	0.97
7	15	0.00093	0.13	13.6	1.0	2	23	559	580	558	580	0.95
8	15	8.8e-05	0.012	16.8	0.6	1	23	588	613	588	613	0.93
9	15	0.0012	0.17	13.2	2.9	1	23	705	727	705	728	0.96
10	15	0.00089	0.13	13.6	4.6	2	23	910	932	909	932	0.96
11	15	0.1	15	7.1	0.1	1	23	938	960	938	960	0.92
12	15	8.4	1.2e+03	1.1	0.5	2	23	968	989	968	989	0.93
13	15	9.8	1.4e+03	0.9	0.4	2	23	1078	1099	1078	1099	0.91
14	15	0.017	2.4	9.6	0.0	1	23	1109	1131	1109	1131	0.95
15	15	1.5	2.1e+02	3.5	1.2	1	23	1138	1160	1138	1160	0.93

Sequence Information

Coding Sequence: ATGATGGCCTTAAAAATGCTGTACCGCGGCCCCAGCTCTAGGTTGGAGAATTTAATCGAAAAGATTCAAGCTACTAAAGAAGTGAACACAGATCTGTACTCCACGCACACCTCTTCCAGCTACTCGCCGTCCATGTCGGATGGGACAATTACTCCGAACTCGTTgcacaaccaccaccaccagaaccaccatcaccatcatcttCAGCGGCTGCATCACTTGCAGTACCAGTGCGAACAGCAGCACAACAGCGGTGGTCACAATCGCGACAGTAGGCATCACAATCGACGGGTTTCAGCCATAAATGGAGCAACTGCCACCGGTGTTGGCGATGGGGACGGCAATGACGaggacgacgatgatgacgacggGGACATCAGGGACGAAGATGACGACGCCGCGAATTCTAGCGAGGAAAGGGTTTTCCTCTCAGCGAACGGTGGTGGTGCCAACGATGCCgccaacaccaccaccaccaccaacaacaacaccaccgccgccgccgccatcaCCACCATCAGTGGCGCAATCGGCGAACATTCCATGAAAATTCCAACGAAATTGCGGAAAATCGATAGGGATTCGGCAAAGTTGTTGGATAAGTTGACAAGTGATGGCATTAAGAGCGCGACCGACCGCGACGGATCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGCCTTGGGTATCTGAAGAAGCATGAACAGAGCCACGCGGAGCATCTCCCATTCAAGTGCGACTACTGTGCACGGCTTTTCAAGCACAAAAGGTCGCGTGACCGGCACACCAAGCTGCATACCGGGGATAGGCGGTACAGATGTCCGCACTGCGAGGCTGCCTTTTCGCGGAGTGACCATCTGAAGATCCACATGAAAACCCACGACAACCAGAAACCCTTTCAGTGCACCATCTGCAACCGTGGCTACAATACAGCGGCGGCTCTGACGTCTCACATGCAAAACCACAAAAAGCAGGCGGCTCTGCTCGCCGCTGGCGGTAACCCCGCTGCACTAAATTACAGCCCACGCTCAACAGGATCCGGTTCGAGTAACGGCAGCCTGCAGAAACGACGATATGCGTCAGTGGCCAATACCAAGAGTCCCAGCCCAAGCACCTTGGAATACGCTAAGCGAGTGCGCAGCTCTATCGTCACGTGCATGTACTGCACCAAGTCTGATTTCGCATCCATGGATCAGCTCGGCATTCACATACAAGCCATGCATGAGAAGGAGGCACTGGCCAATCAGCCCGCCACCAGTGGCTTTCAGATGTCCTGCGAGTACTGCACAATGAAGTTCCCCAGCATCCCGGCAATGTTCCAGCACATGAGAACAACGCACATCGATCGTCTGTCCAGTCCGACGAGCTACTTTGAGCACTTCAACCGGCTGGCGGCATCGGGTACGTTTAGTCCCCGGCTGCCAACGCCCAAGTCGCACGAGACAAAGGTGAAGGTGGAAGAACCGAGTCCCAAGGAGTTGGAGAAACCGGACGACGAACCTACGGATTTGAGTCAAAACAAGCGCTCCGCCCAGACACCGTCGCAGGAGTCTGCCGAAGCCGTGGAGAAACCCGGGGTGTTCTTCTGTAATCAGTGCAACGACGGGTTTCCAGATTTTGACAGCTTCCGCAACCATCTCAAGTCGCATATCGTGCAGGGTCTGAACTTGGTGTGCCACCACTGCGGGCAGTCATTGCGCGACCAGCCCGAGTACGAACGGCACGTGGTTTCTCATTTCCTGATAACCAGCACAGAATACAGCTGCAATGAGAAAAACTGCAGCAAGTCGTTCTCCAAGCCGGAGGAGCTGCAAAAGCACCTCATCGACAGCCACCTCCAGACGATGTACAAGTGCCTGCTGTGCTCGGATCTATTCGAGACCAAGGTTGCGATTCAAGTGCACTTCGCCTGCATTCACTCGCCGGAGAGTAAGGTGTTCCGTTGCTCGGCATGCATGGACACCTTCCACGGAGAGCAGGAGTTCCATATCCATGTGAAGACCCGCCATCAGACGATAGTCGGCTCGCCCATACAGTGCATGTTCTGCAGGGCGGTTTGCTCCACAGAGCTGGAGATGCACTTCCATCTGGCTGCGCATGCACGACAATTCCGCTGTCCATCATGCCCGGAGACGTTTCACGTGGAGTTTCTGCTCGACCGGCACATGCAGACGCACCACGGCCAAAAGGATGTCGAAGCGGCGCCCGTTGTCAATTCGCCAATTAATCCCATCTACATGAGCGCTCTCTTCAATAAGCCACCACCCTCGACCcagaataacaacaacagcattcTGGACTACAACGCCTTCGCCATGGGAAAGAACCTGTTCGCCAATGCCGCGGGGAACACGAGTAAGTTCTACAATCCGCTGCAGGTGGATACGAGTTCCACCATGAAGCATCCCTCCCTTGTGTACGCCAGCTTAAACCAGCGCTACTTCGACACCAACCGGACTATTCTCGAGATGTATAACCAGCACCAGCAGGAGAAGACTAGCGGCGCCACAAACTACTTCAACAGCcctaacaacaacaataacaacaacaaccacagccGGAGCGCTCCTAAACCTCAGCAGGAAGGTAACAAATCGACGGACCGAGCTGTAGGCGGTGGTGGTTTCAGCTGTGGCATGTGTGAACGTAACGACTTCCGAACTGAGGCCGAGATCCATTCACACCGCAAGATCGTTCACAATCTGAAGACTGGGGTCAGTCTCCGCTGTGCTTACTGCAGCGGTAACTTCAAGTCTCGCAGCGAGCTGGAGCACCACATGAAGACGTGCCACAACTCGACAGGGAAGCACAAATGCCTCATTTGCGACGAGATCTTCCCCTCCCCCGCTATCCTCGCCGAGCACAAGCTGCAACACTCGAAAGTGGGGCAGTCCGGCAAGTGTTCGCACTGCGCCCACGCCCTGGCAGACGTGGCTGCCTTCAAAGGCCACCTGTTGGAGCACAACACCGAGGGCCAGATGCCGGTTCAGTGTATTTGCTGCCGCCAAACGCTTCACTCCGACTTTGAGATCGGTCTGCACGCCAAGTTCCACACAAAGTCGTCATCCGTCTCGGAGAGTGCGTGCGCCCTGTGCCTGGAAACCATACCCAACACAGCAGACGCCAAGGTGTGCGAGAAATGCTGCCGCAAACACAACCTGAGCACCAAGTTCAACAGCCAGCGGAACTTCGAAAGCAGCTCCGGTCCCTCGAACTACGTGGAGAACCGCTGCAACTTGTGCAAGGTCATCATGCCGCATGCGCAAAAACTCCAAGAGCACCTGGTCGAGCACACTTTCGCCGGCTGCGAGGACCGAGGCTTCATATGCTACATCTGCTCCGCGGTCTTCACAGCGCCCGGTGGTTTGCTGAGTCACATGGCCGACCACGGTGCCAACGCTCGCCCATACGACTGCAACCTTTGCAGCGACAAGTTCTACTTCCGCGCGGAGTTGGATCACCACCTGGTCGAGCACGAGGCAAGAGGTCGCCTGAAGCATTCAAACGCCGGCGAGGCAAACCCCCACCCTGAGAGCAAGAAGCCGTTCGAAGAGCCTCCCCCAGCACAAGAGGCAGCTCCCAAGCTGGAACTGAAGAACGAGGTCGTTGAAGAAAAACCATCAGCCGCCGCGGACGAGGATGACGACGAGTACATTGAAGTGGAAAAGGTGCCAGAAGTCTCAATGGACACCGCCCCCCAAGAGGACTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEVNTDLYSTHTSSSYSPSMSDGTITPNSLHNHHHQNHHHHHLQRLHHLQYQCEQQHNSGGHNRDSRHHNRRVSAINGATATGVGDGDGNDEDDDDDDGDIRDEDDDAANSSEERVFLSANGGGANDAANTTTTTNNNTTAAAAITTISGAIGEHSMKIPTKLRKIDRDSAKLLDKLTSDGIKSATDRDGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCDYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQAALLAAGGNPAALNYSPRSTGSGSSNGSLQKRRYASVANTKSPSPSTLEYAKRVRSSIVTCMYCTKSDFASMDQLGIHIQAMHEKEALANQPATSGFQMSCEYCTMKFPSIPAMFQHMRTTHIDRLSSPTSYFEHFNRLAASGTFSPRLPTPKSHETKVKVEEPSPKELEKPDDEPTDLSQNKRSAQTPSQESAEAVEKPGVFFCNQCNDGFPDFDSFRNHLKSHIVQGLNLVCHHCGQSLRDQPEYERHVVSHFLITSTEYSCNEKNCSKSFSKPEELQKHLIDSHLQTMYKCLLCSDLFETKVAIQVHFACIHSPESKVFRCSACMDTFHGEQEFHIHVKTRHQTIVGSPIQCMFCRAVCSTELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHGQKDVEAAPVVNSPINPIYMSALFNKPPPSTQNNNNSILDYNAFAMGKNLFANAAGNTSKFYNPLQVDTSSTMKHPSLVYASLNQRYFDTNRTILEMYNQHQQEKTSGATNYFNSPNNNNNNNNHSRSAPKPQQEGNKSTDRAVGGGGFSCGMCERNDFRTEAEIHSHRKIVHNLKTGVSLRCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCAHALADVAAFKGHLLEHNTEGQMPVQCICCRQTLHSDFEIGLHAKFHTKSSSVSESACALCLETIPNTADAKVCEKCCRKHNLSTKFNSQRNFESSSGPSNYVENRCNLCKVIMPHAQKLQEHLVEHTFAGCEDRGFICYICSAVFTAPGGLLSHMADHGANARPYDCNLCSDKFYFRAELDHHLVEHEARGRLKHSNAGEANPHPESKKPFEEPPPAQEAAPKLELKNEVVEEKPSAAADEDDDEYIEVEKVPEVSMDTAPQED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01542500;
90% Identity: iTF_00314731;
80% Identity: -