Cvar023745.1
Basic Information
- Insect
- Cheilosia variabilis
- Gene Symbol
- -
- Assembly
- GCA_951230905.1
- Location
- OX579679.1:23635349-23637107[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.079 11 7.5 1.7 3 23 163 184 161 184 0.93 2 10 0.082 12 7.5 0.1 6 23 193 210 193 210 0.98 3 10 0.00029 0.041 15.2 6.1 1 23 216 239 216 239 0.96 4 10 2e-05 0.0028 18.8 6.2 1 23 249 271 249 271 0.99 5 10 0.00019 0.026 15.8 1.3 3 23 283 304 274 304 0.92 6 10 0.00039 0.055 14.8 0.8 3 23 312 332 311 332 0.96 7 10 0.0082 1.2 10.6 0.0 2 23 340 362 339 362 0.91 8 10 0.00046 0.065 14.5 0.4 1 23 370 393 370 393 0.94 9 10 3.6e-07 5.1e-05 24.3 3.9 1 23 399 421 399 421 0.98 10 10 0.00069 0.097 14.0 9.6 1 23 427 450 427 450 0.96
Sequence Information
- Coding Sequence
- atgttgtGCAGACTGTGTGTAAAAGAATGTAGtgattttacaaatattttcgaAGGTGAGGGTCTACGAAACGATATTCCAAATCTTATTGCAACCTATTTTACATTCCAAgTAACGCAAGATGACGAGCACTCGACTATTGTCTGCAGAAATTGTTTCAACAACCTATGCAATTTTTACACTTTTTGCATTACTCTGGAAAACGCCCAGGAAAAGTGGCAAACACTTCTGGATCCACTGGTAAATGAGCAATTACTTGAAGAATCTGAATCAAGCCCGATAGACAATGACAATACATCAATACATGAGGAATTTTCTGAATTCAAATGCAGTCAGAGTTCCAATTCGCAAGATCAAGTCTATGAAGAAAATCACAGCAACCGTGCTGATACTGATTCTCCAACTTTTATTCCAGAGGATAAATCCAATAGGTCCAAACTCTCTAAAGGGTTCGATCGTTTAATATCATCATACACAACATTGTTTTGCAATGAATGCAATGAGACAATGGAGAACTTTAAAAGCCTGAAAAAACACTTCAAACAAGTTCATGGAAAGGCCGGCTACATGATATGCTGCAAAAGGAAATACTTTAGAGCCGCTGACCTTGCCGACCATATTAATATACATTTAAATCCGGAACACTTCAAGTGCACGCAGTGTGGGAAATGCTTTTCAAGCCGTTATAGCTTGGATTTTCACCTAAAGACGTTCCATTTAAACGAAAATAAGGAAAGACAATGCTTCAAATGCAAGCACTGTTCACGGgcatttaccaaaaaaaatatgctggAGAGGCACAAACAAACTCATTTTGAAACTAATTCAGATGCTAACAATCATTTGTGCAAGGAATGTGGAAAAGGCTATCCAACCGAATCCAAACTAAAGGCGCATCATTTTAACGTACACACAATGCTCTACAGCCGAATGTGTCATCTGTGCGGTAAAATTGTTCGCGGAAATAAAGCACTGGAGCGACATCAACTACAGCACGCCGGAATCAAACCGAAAGTACAGTGTGAAGTATGCGGCACGAAACTATCTACAAAGGGCATTCTAAAAGCCCACATGGTAGCCCTGCATCCAGAAGATACCAGTGAAACTCATGTTTGTAACGTATGCGGTAAAAATGCGCCCAGCAAAAGAGCTCTGAAATACCACATGGACTACGTTCACAGATGTGAAAGGTCGCACAAGTGCAACCTCTGTGACAAGTCTTTTAAACGCCCACAAACCTTAAAAGAACACATGACAACTCACACAGGGGATCGGTTGTATGAATGCCCGCATTGTCCGAAGACGTTTAAAGTTTGCTCGAATATGCATCATCATCGCAAGCTAAAACATCCCAAAGAGTTTGAGGAAAACCGAAAGAACCGCACAAAAAGGAAATAG
- Protein Sequence
- MLCRLCVKECSDFTNIFEGEGLRNDIPNLIATYFTFQVTQDDEHSTIVCRNCFNNLCNFYTFCITLENAQEKWQTLLDPLVNEQLLEESESSPIDNDNTSIHEEFSEFKCSQSSNSQDQVYEENHSNRADTDSPTFIPEDKSNRSKLSKGFDRLISSYTTLFCNECNETMENFKSLKKHFKQVHGKAGYMICCKRKYFRAADLADHINIHLNPEHFKCTQCGKCFSSRYSLDFHLKTFHLNENKERQCFKCKHCSRAFTKKNMLERHKQTHFETNSDANNHLCKECGKGYPTESKLKAHHFNVHTMLYSRMCHLCGKIVRGNKALERHQLQHAGIKPKVQCEVCGTKLSTKGILKAHMVALHPEDTSETHVCNVCGKNAPSKRALKYHMDYVHRCERSHKCNLCDKSFKRPQTLKEHMTTHTGDRLYECPHCPKTFKVCSNMHHHRKLKHPKEFEENRKNRTKRK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00312079;
- 90% Identity
- iTF_00311324;
- 80% Identity
- -