Cvar022605.1
Basic Information
- Insect
- Cheilosia variabilis
- Gene Symbol
- -
- Assembly
- GCA_951230905.1
- Location
- OX579679.1:3526995-3529054[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 4.3 6e+02 2.1 2.1 3 23 182 204 180 205 0.75 2 13 0.00041 0.058 14.7 2.7 3 23 213 233 211 233 0.97 3 13 3 4.2e+02 2.5 0.2 3 10 240 247 238 249 0.84 4 13 2.2 3.1e+02 3.0 4.0 2 12 268 278 268 291 0.79 5 13 1.7e-05 0.0023 19.1 6.2 1 23 297 319 297 319 0.98 6 13 4.7e-06 0.00066 20.8 0.4 1 23 325 347 325 347 0.98 7 13 0.00011 0.016 16.5 4.2 2 23 353 374 352 374 0.97 8 13 0.018 2.5 9.5 1.6 2 20 384 402 383 406 0.86 9 13 3.2e-05 0.0044 18.2 2.9 1 23 431 453 431 453 0.99 10 13 5.7e-06 0.0008 20.5 2.6 1 23 459 482 459 482 0.97 11 13 7.7e-06 0.0011 20.1 0.1 1 23 488 511 488 511 0.94 12 13 1.8e-05 0.0026 19.0 0.2 1 23 517 539 517 539 0.98 13 13 0.00015 0.021 16.1 4.3 1 23 545 567 545 567 0.98
Sequence Information
- Coding Sequence
- ATGAGTGTCGTGGACAATACTTGCAGAACGTGTGGAAAGCCATCTGATCAAGAAGATGGCTCTGATCTCCACCCAATGTACACTTCAGTTGAATACCATAACGAGTTGACAATGGTTCAAGAGGAATTCGAAATATGGAATCTTAATATTGCTCAAAGCGATGGCCTACCTCAGAAAATTTGCCTTACTTGTTTCGATAGTTTCTGTCAGATTCACAACTTTCGCTTGATATGTCAAGAGGCGCAGGTGAACTTTGGCGAACTATGCACTGGCCTGGACATCATAATCAAGGTCGAACCCGAGAATGGAGATATCGATGCAGACTATCCAGACGATTTCGATGGCGAACAGACAATCACTGTTCAAGAGCGCTATCAGTTTCCCGGTGATGTTCAGTTGAAGTTACTTAATCTCCAGGAAGAAAAAACATGTGAAAAACTTTTGGAGACTGTCAATTCGGACGAAGAGTGTCGTATTGAGCAAGACCGCAACGAAGAGATTGAAGAACAGAACGCTGTTATTCCCGAGTTCAAACAATTCCAATGCAAATTCTGCATGGATGTTGTAGGTTTCGATGACCCAGAGCTATTAAACCAGCACTACAACCTGCACCACTCTACGGATCTCCCCTATGGGTGTCCGAAATGTGAAAAGTGCTTTGACAACAAAAGTAAACGAAATAGCCATGCTAGAGTTCATTACCGGATCGTACTGGACTGCCCGATTTGCAATAAGAAAGTGCGTGGTGGAAAGCGGATGATGGCCCAACATCATGAATTCTATCACATCGAAAAGGATCGCGAATGCAAAACTTGCGgcaaaaaattcattaaaacaactttGAAGAGATTTAGGTATCACATGAGTTGGCATGATGAAACCAAACTGCACAAGTGCAAATTCTGCGATAAGAAGTTTATCCAGCTAACACATTTGGTGGTCCATCAAAGGACGCACACGGGCGAGAGTCCGTTTGTCTGCAGCGAGTGTGGCAGTGTATTCAAAAATTCTGGACTCCTGTATTCGCACTTGAAAACGCACGGAAAGGGAGAACTAACCTGCAATGTGTGTAAGAAAAAATTCTTCCATCCTCACGGCTTAAGGCTTCACATGCTAATGCACGATCAAAAAATACCGAAACAAGGACTTCGCTGCAATATTTGCGACAAAGCGTTCGGGACGTGTTTGAATCTGGACCTACACAACTACAATAAACATGGAGCACTAGCGACAGCGTCTGTTACAAATGTTTTGAATAAGCGAAAGATAAAACCAGTACTAATCAAACCATACAAATGTGGCAAGTGTCCCCAATCGTTTGTACTGCATACACAGCTGATGAAGCATCTGAAAACACATGACGAGTACAGGCCGTATACGTGTGAATTttgtcaaaaatcgttcaaGCGCGAAGCTCATTTAAAGTTACACGTCAATTCGATACATTTGAACAAGAAGCCGTACAAGTGCACAATATGCGGGTGGGCCTTCATACTGAGGAACAATCTCAAACAGCACATTGCCGCGAAACATGAGACCAGAAGGGACTTCAAATGTGAGATTTGTGGAAAGGAGTTTGCCATTGCCAAGGTGCTGAAGACTCATATGATCAAGCACACGGATGAGAAGCCGTTTACCTGCACCATATGCAACAAGAGCTTCCGTATGCTGACATGTCTCAAAAGTCATGTCAACAATCATCTTAAGAAGAATGAAGCCAATGTTGCTGCAGGAGATATTACAGATATTGTTGTGGGcgaaaattcttatttttaa
- Protein Sequence
- MSVVDNTCRTCGKPSDQEDGSDLHPMYTSVEYHNELTMVQEEFEIWNLNIAQSDGLPQKICLTCFDSFCQIHNFRLICQEAQVNFGELCTGLDIIIKVEPENGDIDADYPDDFDGEQTITVQERYQFPGDVQLKLLNLQEEKTCEKLLETVNSDEECRIEQDRNEEIEEQNAVIPEFKQFQCKFCMDVVGFDDPELLNQHYNLHHSTDLPYGCPKCEKCFDNKSKRNSHARVHYRIVLDCPICNKKVRGGKRMMAQHHEFYHIEKDRECKTCGKKFIKTTLKRFRYHMSWHDETKLHKCKFCDKKFIQLTHLVVHQRTHTGESPFVCSECGSVFKNSGLLYSHLKTHGKGELTCNVCKKKFFHPHGLRLHMLMHDQKIPKQGLRCNICDKAFGTCLNLDLHNYNKHGALATASVTNVLNKRKIKPVLIKPYKCGKCPQSFVLHTQLMKHLKTHDEYRPYTCEFCQKSFKREAHLKLHVNSIHLNKKPYKCTICGWAFILRNNLKQHIAAKHETRRDFKCEICGKEFAIAKVLKTHMIKHTDEKPFTCTICNKSFRMLTCLKSHVNNHLKKNEANVAAGDITDIVVGENSYF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00311271;
- 90% Identity
- iTF_00311271;
- 80% Identity
- -