Cvar025494.1
Basic Information
- Insect
- Cheilosia variabilis
- Gene Symbol
- -
- Assembly
- GCA_951230905.1
- Location
- OX579679.1:56517919-56521746[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0021 0.3 12.5 4.9 1 20 69 88 69 90 0.95 2 12 0.29 41 5.7 2.7 2 21 114 133 113 134 0.89 3 12 0.00057 0.08 14.2 1.6 1 23 154 176 154 176 0.96 4 12 6.3e-05 0.0089 17.2 0.2 1 23 206 228 206 228 0.96 5 12 1.8e-05 0.0025 19.0 1.1 1 20 233 252 233 254 0.93 6 12 0.00066 0.094 14.0 0.5 3 23 673 694 671 694 0.96 7 12 0.19 27 6.3 0.2 3 23 723 744 722 744 0.94 8 12 0.0016 0.23 12.8 3.6 1 20 755 774 755 776 0.93 9 12 4.2e-05 0.0059 17.8 1.2 3 23 786 806 784 806 0.97 10 12 1.5e-06 0.00021 22.4 2.4 1 23 812 834 812 834 0.99 11 12 5.1e-05 0.0072 17.5 2.4 1 23 840 862 840 862 0.98 12 12 0.02 2.8 9.4 0.1 1 20 868 887 868 889 0.95
Sequence Information
- Coding Sequence
- ATGACAGAAACTGACGTTGAAATAAAAACCGAACCCTTGGACGATGAAGGTGCACTATTTAACGAGGaagaattaataattaaaaGTGAAATTGATATTGAAGAGACCTCATTCATCCCTACTGCAGTGCCAAACTCATTCGCCATGAATTTCCAAGATTACTATGCCAAAGTTATACCCAAACGACCGCTGTCTCCGAGTACGTTTCAATGTCATGAATGCAAGAGATTTTTCGTCAGCGAAAGTTCGCTTTTCAACCATAAGTGCCTCGGAAAGCAGTCACGCGAGTACAAGCAAGCTTGCGAAAATGAACGGAAGATGCTGAAACACAAACGCCTTCAGTGCGACAAGTGTAATCGAAAATTTCAAAGTCGCACAGAAGTGCTCGATCACAAATGTAAGAAAGCCGAATGCACAAACTCTAAGGACGATGACAAACGCTTACGAGGTCGCACCATGTACAAGTGCACTATTTGTGGCCAGACATTTCGTACATTGTTTATTTTCGAAGAGCACATGCAATTTCACAGGAACAAGCTCAAGCGTTCCCCTGTGAAAGCACGCAAGGCAATGTGTATTGTGCCGAAATCGCTCCTTGATCCCAAAGTAATGGTCTTTGCATGTAATCTTTGTGATATTAGTTTTTCGACTGCTAAGGGCTTGCAGAACCACAATATGGTGCATGGTGGAAACGAACACATCTGCAAGAAGTGCGGCAAATCCTTCAACCGCGCCattcatttaaaaacacataCCATTGGTGACACATGTACGAAGGAAAGCGTGGCTGATCTCCTCGGCAGCTGTGGCAGTGAGGGTAGCGTGGACATCAAGGCAGAAGCTGAAAGCGAAGACGATGTCCCAATGGAATCGGAGGGGGAAAGTTGTAAAGCTGACACAGCTATATTCACAGGAAAAACCTTTGGAGAGAAATGTGTCACTGTACATGATAAGCATCACACACTCATGTCGGAGCCGGGAAACTTTGCCGCTACTGTGCCGCAGCTCACGCCAATGTACAGCTCACAAGATCAAGATGTTCCTTTGCAAGCCCAGCGAAACGAATTTCCGTTAAGTAATAAACAAAGTCACCGAAGACTGCCGTTCGCTCCTCAACGGCTGGATGTTATCATCGATGGCCTGGGCAACGCATTTGTGATGAAAAAGGAAGATCTCATCACCGGCGCTCTGCAGTACCCGCaaatcaaaaagtttcaaaacgaACAGGTGGTTGTGGATGCCCAGGGCAATGCTTTCAAGTTTAGTCAAAAACCGCAGCAAGATGCTTTCTTCATTGGCCAAGATCATTGTTATACCAAAAGTTATCCTCCTGTCGCCGAAGTCAAAGAAGAGCCAACAGAACTCGAAATAGAACCCCCGTCCGATCCGATTAACTATGAAGACCTTATTGTTGACGAATCCCCCGAGCTTACTATAAAAGAAGAGCCTGCTGctgaaatagaaatagaaccCCCATCCGATCCGAAGAACTATGAGGATCTTCTCATCGAGGAGCTGTTTGATCGCAAGGCAAAATCAGTGGCGAGGGTGCGAAAAGCCGCCATGGACATGGTCAAAGGGCGGGTACCGCCAAAAGTCGGTGGCGCAGTGTCATTCAAAGATACTGACTTTGAGGAAGCTATTCCGCCGAATTGTCTTGAAATTTCAAAAGACAACGACCCCGTCAAGGACGAGCCTAGCGATGACCTCGTGGCGAGAGAAACTGACACTGATTGTGCGGTAGAAATGGATCCTCAATGTGCGGATGACTTTGAGGAGATGATCGATTCCGCAACGGCGCCACATTTAGTAGTGAAATGTGAAATAATAGACAATATGCGCGACGAGTACCAAAAGGCAAAGAAGAAGAATCTGGGCGATTCCTCAGCCGACGAGGGGAGCCAGCAGTCATCACAAGGAGCTCCACTCTCAATATTTGTTACGCTAACAGAGTCGCGGAAGTTCTACAACGGGGCCTTTCGAAAATTGGACAAACGCTATCGCTACATATGGATTTGTGCCAAGTGCCCGAAGCAGTATATTCAACGTAATTCTTTCTTCAAGCACCAGATGACTGCCCATTACAAGGACTCGGCTGAACTGAAATCTGAGCTCTTTGAGTTGCGGCCGGAGTTGCTTGCTGAAAATATTGCCGTGGAGGGCTACTGTCAATTGTGCCGTGTGACGCTGGCCGATGCGGTCACCCTGCAGAAGCATAAGAAAGAGATCCATGCGGAAGACGAAAACGCATCCAAGATGCAGTTCAGGTGCCACATATGTGGCAAGTTCTGTTCGTCGCGCAGCACTCTGGGCGATCATGTGCACTCGGATTGTGGCAAAAATCCCCAGTACGGGTGCCAGGTGTGCGGGAAGAAGTTCTATTCGAGAAGTACCCTGCAATTGCATAGAACTATGCACACGGGTGAGTTGCCGTTCAAATGCACGTATTGTGATAAGCGAGTTCGAACGAGGGGCCAGTTGACGGTGCACACGAGGACGCATACCGGCGAGCGGCCGTTCCCTTGCAAGGTTTGCGAACGTCGCTTTACGCATCGCGAGACCCTCATCTCGCACCTCTCGCGTCACATCGACATGAAGAGGTACAAGTGCAACGGCTGTCAGGCGCTGTTCGCTTCCATTTCTGGCCTCAAAACACACCGAGACAATCGTATACAAACCTGTggtaaattcaaattcaactcTCGGCCGATTGGGCCTCGCGTTCGGGTAATCAAGGGCAATGTCATTTTCGAGCCGCAACCAAAATTCAATCCCTACTCGCGGGAATACAACAACGTGTCCGACGGTAATACACTGGAAAATACCGAGGCTGAAGAGCCGGACGACAATAGTTATACCGAGGAAAATGCTAGCCCCTTGGAGAACACCGGCCAAGTAGCGGAAACGCAATCCGACTCAGATGTGACAGACAGTTAA
- Protein Sequence
- MTETDVEIKTEPLDDEGALFNEEELIIKSEIDIEETSFIPTAVPNSFAMNFQDYYAKVIPKRPLSPSTFQCHECKRFFVSESSLFNHKCLGKQSREYKQACENERKMLKHKRLQCDKCNRKFQSRTEVLDHKCKKAECTNSKDDDKRLRGRTMYKCTICGQTFRTLFIFEEHMQFHRNKLKRSPVKARKAMCIVPKSLLDPKVMVFACNLCDISFSTAKGLQNHNMVHGGNEHICKKCGKSFNRAIHLKTHTIGDTCTKESVADLLGSCGSEGSVDIKAEAESEDDVPMESEGESCKADTAIFTGKTFGEKCVTVHDKHHTLMSEPGNFAATVPQLTPMYSSQDQDVPLQAQRNEFPLSNKQSHRRLPFAPQRLDVIIDGLGNAFVMKKEDLITGALQYPQIKKFQNEQVVVDAQGNAFKFSQKPQQDAFFIGQDHCYTKSYPPVAEVKEEPTELEIEPPSDPINYEDLIVDESPELTIKEEPAAEIEIEPPSDPKNYEDLLIEELFDRKAKSVARVRKAAMDMVKGRVPPKVGGAVSFKDTDFEEAIPPNCLEISKDNDPVKDEPSDDLVARETDTDCAVEMDPQCADDFEEMIDSATAPHLVVKCEIIDNMRDEYQKAKKKNLGDSSADEGSQQSSQGAPLSIFVTLTESRKFYNGAFRKLDKRYRYIWICAKCPKQYIQRNSFFKHQMTAHYKDSAELKSELFELRPELLAENIAVEGYCQLCRVTLADAVTLQKHKKEIHAEDENASKMQFRCHICGKFCSSRSTLGDHVHSDCGKNPQYGCQVCGKKFYSRSTLQLHRTMHTGELPFKCTYCDKRVRTRGQLTVHTRTHTGERPFPCKVCERRFTHRETLISHLSRHIDMKRYKCNGCQALFASISGLKTHRDNRIQTCGKFKFNSRPIGPRVRVIKGNVIFEPQPKFNPYSREYNNVSDGNTLENTEAEEPDDNSYTEENASPLENTGQVAETQSDSDVTDS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00316253;
- 90% Identity
- -
- 80% Identity
- -