Cvar023524.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cheilosia variabilis
Gene Symbol
grau
Assembly
GCA_951230905.1
Location
OX579679.1:18063879-18074184[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 28 0.1 14 7.2 0.9 2 23 223 245 222 245 0.96
2 28 0.084 12 7.4 1.8 6 23 254 271 254 271 0.99
3 28 1.4e-05 0.0019 19.4 1.0 1 23 277 300 277 300 0.98
4 28 3.2e-05 0.0045 18.2 4.9 1 23 307 329 307 329 0.98
5 28 0.0013 0.18 13.2 0.2 3 23 336 357 334 357 0.96
6 28 0.0013 0.19 13.1 0.3 2 23 366 388 365 388 0.96
7 28 0.00092 0.13 13.6 1.0 1 23 395 418 395 418 0.94
8 28 0.23 32 6.1 2.3 1 16 424 439 424 440 0.90
9 28 0.031 4.4 8.8 0.1 2 23 691 713 690 713 0.94
10 28 0.034 4.7 8.7 0.6 6 23 722 739 722 739 0.99
11 28 0.00026 0.036 15.3 0.3 1 23 745 767 745 767 0.99
12 28 9.4e-06 0.0013 19.9 0.8 1 23 775 797 775 797 0.99
13 28 2.6e-05 0.0036 18.5 0.3 2 23 804 826 803 826 0.95
14 28 2.1e-06 0.0003 21.9 0.5 3 23 834 854 833 854 0.96
15 28 0.00099 0.14 13.5 0.5 2 23 863 885 862 885 0.96
16 28 0.00063 0.088 14.1 0.0 1 23 892 915 892 915 0.94
17 28 0.0081 1.1 10.6 0.3 1 16 921 936 921 937 0.87
18 28 0.0052 0.73 11.2 0.2 2 23 1141 1163 1140 1163 0.95
19 28 2.2e-07 3.1e-05 25.0 1.0 1 23 1195 1217 1195 1217 0.98
20 28 0.086 12 7.4 0.9 2 23 1449 1471 1448 1471 0.96
21 28 2.5e-05 0.0035 18.5 1.6 1 23 1503 1525 1503 1525 0.99
22 28 0.009 1.3 10.5 5.1 1 23 1533 1555 1533 1555 0.99
23 28 9.4e-05 0.013 16.7 0.2 1 23 1563 1586 1563 1586 0.96
24 28 0.0055 0.77 11.2 0.2 3 23 1594 1614 1593 1614 0.96
25 28 6e-05 0.0084 17.3 0.7 2 23 1623 1645 1622 1645 0.97
26 28 0.00019 0.026 15.8 0.1 1 23 1652 1675 1652 1675 0.94
27 28 1.1e-06 0.00016 22.7 0.9 1 23 1681 1703 1681 1703 0.98
28 28 4e-05 0.0057 17.9 5.0 1 23 1709 1732 1709 1732 0.98

Sequence Information

Coding Sequence
atgcttTGCATGCTGTGCCTAACGGCATCGGATAAAAAAATTAGTATATTTGATGTGGAAGGAATTCGGCTCAACATCAGCACTATTATCACTAAACACTTCTGGCTGCAGCCAAGTATAGAAGACTTCAATAAGAGCACAATCTGCTGTTCCTGCTGGCAGGCATTATACTCATTCCACGAGTTCTACCAAAAAGTGGAGAAAGCCCATGACAAGTTTTCAAATGCGAAATTTCCAATTGACTACGATCTGCCGAAAACCAATGATTTTGGTGCATGTTCTGAGTTGTGTGCCGAAGATATCAAAGTGGAGTCGTGTGGGGAACCTAAGGTTGATCTGACAAAAGTTGAAGTGCAACTATTTATCGCTGATGAGAGTATGGAAAAACAAACCCAAATAAAATCCGGCTCTGAATCGGATGTGCCTTTAGGTAAATTGAATGCACTTCGAAAGCCAACCGAGAGTAGTGAACCCGTGTCGGACACCGATGATGATTACAATAATGAAGGTGATACCgaagaagacgacgacgaagaaAATGATACCGACTATAAAGTACCTGAAAACAAGGAGGCAGAAAATAGTGCCACCGCCAAGAGGGAGTATAATAAGCACCGAATTCCCTGTAAACAATTCGATGAGATTATCAAACAGAGTATGAAGCTGTCGTGTAACGTTTGTCACATTGCTTTGGAAAGTTTTTTCACTCTGAAGGAACACTATAGATCTGCTCACAATAAAACCGGCTACGTAACCTGTTGTGAGAAGAAATTCGACAGCCGTCATGCCCTGGTTCATCATATTCTTATGCACAAAGATCCCGAGACATTCAAGTGTTTGAAATGCGGTCGCGTCCTAGCCGACCGCAGAGGCTTGAAACGGCACATGAAAACGACACATGTAAATGAGGATCGTATCCATCAGTGTCAGAAGTGTAAAAAGGGTTTTCGGCGGAAAGAACTGCTAGAGAAGCATGAAAAAACACATGTGAGACCTGAGGTCATATGCGAACAGTGTGGCAAGGTAGTTCGCGGCAGGCAGTATCTCAAACAGCATCAGTTGCGGGAGCATTCGGGAATACCGAAACAACGTCAACAGTGCCCTAAATGTGGCGTTTACCTTGCGGATAATTCAACTCTATCCACTCATATGAAGTATCAGCATCCTGTTGTTAAAGTTGTGCACGAGTGTCATATTTGTGGGAAAATCTCTGCCACTGGTTACGGCCTGAAGCGTCACATAGAATACATGCACACGCGGGGACGGCCGCATAAGTGTACACTGTGCGAAAAGGCTTTCAAGACGCTAAAGTGTCTGcggCCAAATGAAAACGATGTAAATTCAAATGTTATATGTCCCTCCTGTTGGGGCAATCTGGAGTCCTTTCATAAATTCTATATGAGAGTTCAAGATGCCCATGTTCGATTACAAAACACCAATCCCATTGACGAGGATGAATTGAAACTGGAAAGGGAAATTGCAGAAGCGCTTAGAGCTGCAAATGATGAGGACTTTCATGAGATATTGCCCATACCGGAGGTACTGGAAGCAGACGTGAAAGTAGAAGTTAAAGAAGATACCGACGCAGCCTTGCCACTGACCATTGGTCCAGTTGGTAATGAGAAATATATTGCATCTCAAATCGGTTCAACTTGTGAAAGAAGGATCTCCACAGATTCTGGAAACTCAGTACAGAATGAAACCCCACCCGCGTGCTCTACAAGAAGTCGTACTTCTGTTGAAAAGCCTTACGCCGAAAGCGATTCGTCCAGTGACAATAAAATTGACAACGATGATACAACTGAGATGCAGACCACATCATCAGACTGGCTGGATCCAGACTCCGACATCGACGATGACAATGATGACAGTGACTATGACGCCATCAGCACAACGACATcaaaatcgaaatcaaaaagGCAGAAGGCGCCTCGAAAAACAACGACGAAACGTAAGTGTAAGAAAAACGAAGACGAGCCACAAAAGAAGAAGCGTACATCAGAGCGGGTAACCAAGAAAATGGAACGCATGAAAGAGTACGATGAAATAATTGCCAAAAGCATGAAGCTATCGTGTGATATCTGTGGCGAAGCATTCGCAAACTTTGCCATTATGAAGCGTCACTTTCGGTCTGTCCACAAAGAATGCGGCTATATTGCTTGCTGTGGCAAAAAGTTTCGTAAACGCGGCGTTCTCGTCGACCATATTTGTACCCATCAAAATCCCGAGTACTTCAAGTGTGAGAAATGTGGGAGGATTCTAGCCAGTCGCAAAGGTCTCGATAGTCACATGTTAACCCATGACACGGAAAAGCAGCGCATCTATCAGTGTGATCAGTGCCCAATGAGTTTCTATACGAAGCCACTGTTGTCACGCCATTTGCAAACGCATCTTTCCGAACGCAATATAAAGTGTCCCGAATGCGATAAGCGCTTCTCGACACAAGACATCTTACGCacacacataaacaatgttcaCAATGCGGCGTACACTAGAATTTGTGATCAGTGTGGAAAGTCGTTCCGTCGGCCGGACGCCTTCCGCAGGCATCAATTGGAGCACGATGGCGTAACACGGCCACTTGTTCCGTGCGAAAAATGCAGCGTGAAACTGACCAGCAAATATGGCCTGAAGCGGCACATGCAGTCGATGCATCCCGAGACGGATATGAAACATGTGTGCGACGATTGCGGGAAGATCGCACCCAGTGCGGCGGCCTTGCAGCGTCACATATCGTACATGCACAAAATGGAACGGAAATACAAGTGTCCCATGTGCGATAAGGCATTCAAGAAGACCGGCGGACTTAAGCCGATTGCAGATGATGGTAGTGCAAATGTTATATGCCCGTCCTGTTGGAGTACGTTGAGTTCATTTCACAAGTTTTATCTAAAAGTCGAAGAAGCTTATCAGAGTCTGGAAGAGGCTAATATGATTGCAGCAATGGAGTCGAAATTGGAACCAGAAATGGACGAAGATATCGAAATAACTCCAAAGACTGAGATAAAGATTGAGGCGGAAGAAATTTTCGAACAAACAATGCCATCGGTCACAGCATTCGAATCACAAAGCGATACCAAACCAACTGTCATGCCAAAGACTGCTCCACCCGATACATACTTGAGGAAATTCTTCGGCGATGAGGCTCCATCAACCAGTTGTATAGGAGGACGAACTGACTCTGCCGAAGGCAATGTTTGCATCGTTAAGACGGAGAGTGACAATGGAAGCTTGTCGACAGACTGCCAGAATCAAAATTCGGACTTCGATGACAGTGGCTGGGAAAACAGCTCATCAAACCAAACGAAAccgagaagaagaaaacaaaaatcctgTGACGACAGAAACACAAAGCCGCGAACACCAAGAAGCATAAAAATGAATGAAAGCGATGAACTTATTACAAATACTCTGACATTATCATGTGATATTTGCGATTTGATATTTCCGAGCTTCACTGTTCTAAAAAAACATTATCGTTTAGCGCATAATCAAAATGGTTATGCCACGTGCTGTGGCATACGATTGTTTAAACGCTGCATTCTTGTAGACCACATCAACAGACATAAGAACCCACAGTATTTCAAGTGTGACGAATGTGGACGCGTTCTTTCTACTCGCAAAAACCTAAAACGCCACATGCTAATGCACAATTTGGATCAACGCACCCGAAACTACCATTGCGACAAGTTTGAAGAGGCTCATATCACGTTGGTCAAAACGAGTACCAACGTACAAGACGCTTTAAAACAGGAGAATGAACAAATTGCCATTCAGGCGCAAGATCAATATGTGGAAAAACTCGTTCCCAGTACGAATGCGGAATTTTTGAATGCAGACGTAAAGGAGGAGGTTAAGGAAGATGCAGACGCAAACTTACAGCAAAGCGAATCGCCTCCTGAAAATGAGTCAAATATCGCTGTCTCCAAGACGAAATCAGCGCCAGCGTCAACGCATTCAAGCGACTCTGAGGACTCTGAATCGGAAATTCCGCTTGCCAGCTTAGCCAAGACACGGTCTAAGATGAAAGCCACAACAAAAGCAGAATCTTCGGACAACGATGATATGGCCTCTGTAGCCGACTGGCAAGACCATCACGACGTTGACGAAGACGATGATGAAGATGAcaacgaagacgacgacgaggaAGATATTGAGAGTGAATTTGAAGTAAAGAAAGAGTTGCCAAAACGAAAAGTGATAACAAAAACAGGTAAGAAACGGGGTCGACCATGTAAAAACGCCCCCAAAGATTCGACCCCTAAAAAGACTACAGAAGAACAAATTAAGAAGCGAGAACTCTCCAAGGAATACGATGATATAATCATGAAGAACATGAAGTTAACGTGCAACATTTGCCTTCTACCGCTGGTCAACTTTTTCTCGTTGAAAAAGCACTACCGGTCCAAGCACAATGAACGAGGGTTCGCCTCATGCTGTGGCAAGAAATTCCTGAAGCGTGGTATTCTGGTCGACCACATATACACTCATCTAAACCCCGAACACTTTAAGTGCGACAAATGTGATAAAGTTTTGGCCGATCGTCGATGTCTCGAGGTGCATATGAACACGCACGTGACCGAAAAACAGCGCATTTATCAGTGCGACCAATGCTGCAAGAGTTTCTACAAGAAACCACTGCTCACGCGTCATCTTTACACTCACATTCCCGAGGAGGATCGTAAATTCCCCTGCGAGGAATGCAATAAATTCTTTCCATCGGGTTATACTCTGCGAGCGCACATCAACAACGTGCACCAAAATGTGTATGCGAAAATCTGCGATCAGTGCGGCAAATCGATACGCGGACGGGAGGCATTCCAACGGCATTTGCTGGAGCATGCCGGTGTAGCATTGCCCAGTGTGCAGTGCGACAAGTGTGGTGCGAAATTAAAGAACAAATACGGCCTTAAGAGGCACATGAACTCGATGCATGCTGAATCGAGTGTGCCTCATGTGTGTAATATCTGCGGCAAGGTGGCGCCCAATCCGGCCGCACTACAGCGTCACTATTCGTATGTGCATAAATGCGAGCGAAAACACAAGTGTCCCATGTGTGATAAGGCCTTTAAGAAAGCCGGTGGACTCAAGgaGCACATGTCAACCCATACCGGAGAAGTGCTGTACACGTGTCCCCATTGCCCGAAAACGTTCAACTCCAATGCCAATATGCATTCGCATCGAAAGAAAATGCATCGAAAGGAATGGGAGGAGAACAGACGGCATCCGCACATGGGAGCCGTTGCAAACGCCGAATAG
Protein Sequence
MLCMLCLTASDKKISIFDVEGIRLNISTIITKHFWLQPSIEDFNKSTICCSCWQALYSFHEFYQKVEKAHDKFSNAKFPIDYDLPKTNDFGACSELCAEDIKVESCGEPKVDLTKVEVQLFIADESMEKQTQIKSGSESDVPLGKLNALRKPTESSEPVSDTDDDYNNEGDTEEDDDEENDTDYKVPENKEAENSATAKREYNKHRIPCKQFDEIIKQSMKLSCNVCHIALESFFTLKEHYRSAHNKTGYVTCCEKKFDSRHALVHHILMHKDPETFKCLKCGRVLADRRGLKRHMKTTHVNEDRIHQCQKCKKGFRRKELLEKHEKTHVRPEVICEQCGKVVRGRQYLKQHQLREHSGIPKQRQQCPKCGVYLADNSTLSTHMKYQHPVVKVVHECHICGKISATGYGLKRHIEYMHTRGRPHKCTLCEKAFKTLKCLRPNENDVNSNVICPSCWGNLESFHKFYMRVQDAHVRLQNTNPIDEDELKLEREIAEALRAANDEDFHEILPIPEVLEADVKVEVKEDTDAALPLTIGPVGNEKYIASQIGSTCERRISTDSGNSVQNETPPACSTRSRTSVEKPYAESDSSSDNKIDNDDTTEMQTTSSDWLDPDSDIDDDNDDSDYDAISTTTSKSKSKRQKAPRKTTTKRKCKKNEDEPQKKKRTSERVTKKMERMKEYDEIIAKSMKLSCDICGEAFANFAIMKRHFRSVHKECGYIACCGKKFRKRGVLVDHICTHQNPEYFKCEKCGRILASRKGLDSHMLTHDTEKQRIYQCDQCPMSFYTKPLLSRHLQTHLSERNIKCPECDKRFSTQDILRTHINNVHNAAYTRICDQCGKSFRRPDAFRRHQLEHDGVTRPLVPCEKCSVKLTSKYGLKRHMQSMHPETDMKHVCDDCGKIAPSAAALQRHISYMHKMERKYKCPMCDKAFKKTGGLKPIADDGSANVICPSCWSTLSSFHKFYLKVEEAYQSLEEANMIAAMESKLEPEMDEDIEITPKTEIKIEAEEIFEQTMPSVTAFESQSDTKPTVMPKTAPPDTYLRKFFGDEAPSTSCIGGRTDSAEGNVCIVKTESDNGSLSTDCQNQNSDFDDSGWENSSSNQTKPRRRKQKSCDDRNTKPRTPRSIKMNESDELITNTLTLSCDICDLIFPSFTVLKKHYRLAHNQNGYATCCGIRLFKRCILVDHINRHKNPQYFKCDECGRVLSTRKNLKRHMLMHNLDQRTRNYHCDKFEEAHITLVKTSTNVQDALKQENEQIAIQAQDQYVEKLVPSTNAEFLNADVKEEVKEDADANLQQSESPPENESNIAVSKTKSAPASTHSSDSEDSESEIPLASLAKTRSKMKATTKAESSDNDDMASVADWQDHHDVDEDDDEDDNEDDDEEDIESEFEVKKELPKRKVITKTGKKRGRPCKNAPKDSTPKKTTEEQIKKRELSKEYDDIIMKNMKLTCNICLLPLVNFFSLKKHYRSKHNERGFASCCGKKFLKRGILVDHIYTHLNPEHFKCDKCDKVLADRRCLEVHMNTHVTEKQRIYQCDQCCKSFYKKPLLTRHLYTHIPEEDRKFPCEECNKFFPSGYTLRAHINNVHQNVYAKICDQCGKSIRGREAFQRHLLEHAGVALPSVQCDKCGAKLKNKYGLKRHMNSMHAESSVPHVCNICGKVAPNPAALQRHYSYVHKCERKHKCPMCDKAFKKAGGLKEHMSTHTGEVLYTCPHCPKTFNSNANMHSHRKKMHRKEWEENRRHPHMGAVANAE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-