Basic Information

Gene Symbol
YPR015C
Assembly
GCA_032441825.1
Location
CM063727.1:3286183-3291768[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.072 7.5 7.6 4.7 1 23 190 212 190 212 0.96
2 13 0.00082 0.084 13.7 1.8 1 23 218 240 218 240 0.98
3 13 3.1e-05 0.0032 18.2 1.4 2 23 246 267 245 267 0.97
4 13 0.033 3.4 8.6 0.3 2 20 274 292 273 294 0.91
5 13 1.9 1.9e+02 3.1 0.6 2 23 314 335 313 335 0.94
6 13 1e-05 0.0011 19.7 2.2 1 23 365 389 365 389 0.98
7 13 5.1e-05 0.0053 17.5 3.0 1 23 395 417 395 417 0.98
8 13 0.00017 0.017 15.8 6.4 1 23 423 446 423 446 0.97
9 13 0.0036 0.37 11.7 3.7 1 23 456 479 456 479 0.93
10 13 4.9e-06 0.00051 20.7 1.0 2 23 714 735 713 735 0.97
11 13 7e-06 0.00072 20.2 0.7 1 23 741 765 741 765 0.98
12 13 0.0034 0.35 11.7 0.2 2 23 773 794 773 794 0.97
13 13 3.8e-05 0.0039 17.9 0.9 1 23 800 822 800 822 0.98

Sequence Information

Coding Sequence
ATGGACGATCAAATGGTGTTGGAAAACGCAGAATCCCAATTCATTACTTTATCCGATGTCGGCGAATCGATGGACTCTCGTGCTGCTGAACAATTATCAAATCAGTATACGCCCATAGtttTAGACTCAGACAATTGTCAAGATGTTAGTGATATGTATCCACTAAATGATTTGTTAGTGGGAGAAACATTCATAATAGAAACTAGTGAACGACCTATAATTGTCAACGGTAATcagTTCATTTCATTCCAAAAACTTAATTGTGACAGACAAATAGACAAATTTGATAATGTTCAAACAATTTCAACCGTCGAATTAGAAAAATCAGCAGATCGgattaaatttcgtataaactCTACCGATAGTTTCCAAGACACGTGcacaaattcgaataaaacgaattcaaatgACATAGTAAAAACAACCCATGCTagtagtaatttaaaaaaccattCAGAAATTTCGATCGATACAGATATTGATACGACTGGAGGGAATTATAGTAATTCAGTTGCTATTAAAATCTTAGATGATGTTGCTAAAAGTCCTATTGATACGAATgGTCATTTTGTTTGTGATTTATGTTTGCACGAATTCCACAATTggcgaaattataaaaagcaCAAACTAGaacatttaaatgataaaccatttaaatgtttaaaatgtttaaaatcatttaattataatACTAACTATTTACTTCACATTGCTTCTCATTCAACAAATAATCTAAAATGTCCTCaatgtaaaaaagaatttaaacgTGTAGCTAGTTTTAAGTCTCACttgaaaattcataaaattgaaGAATCAATtacttgtaatatttgttataaaatattcgacaatcagtaTCGATTAGACATTCATAAAGAACATTGTAtgcaagaaaatataattagtcTTGATAATCCAACGAAATTATCTTGTTTTAAAACTTGCAAAACCtgtaaaatatctattttgaCTGTATCAGAATATAAAGTGCATATCAAAGAACATAAAAAATTTAATTCAGTGTtgagaaaacaatataaacgtacaacaaaattgaaaaaatcgcataaaactagtaatttaaataaaagatttaaatGTGAACATTTAAATTGTGATTGGTCATTTAATAAGTTAAATCTTTTAATTCGGCATATGAGAACACATACTGGAGAGAAACCGTTTAAGTGCTCATATTGTTCAAGTCTCTTTTCTCAAAAAAGTTCATTAAACAGACATTTATTAAGACATAAAGGATTGCGACCATTCAGTTgtgaattttgtaaaatgacTTTTTCTCAAAAAGgtcatttaattaatcatttgAAAAGATGTCATGCTGTTACAAAAGAAATAACACGCAATCATAAGTGTTCCATGTGTTCTTGTACTTACATTACTCTTAGTgctttaaataaacatttgagTGCATATCatggattaaaaattaaaaaatcaaataaaaatgtaaaaaaaaatattccaaagaGTGTTAAAGTTGATGATATTAatgaaactataaatttaattaaagATTCTTCAAATTTAGAAACATTGCTCGGGGAAGTAACTCGTGAATTGCAAAATAGTGACAGTAATACTAAATCAAAGAAgcaTTGTGATACAGTTTCTACTCaatgtaattttgaattaaattcaattaataatgaagATTGTGACCATATCGACAACAGTTTTAGTTCCAATATAAAATCTACTAGTTATCAAAtggatattgaaaatttaacaaattctcCACAAAATGATGAACATATTATGGTATCTCAGAATAAAGATGAACAATCATTTGGAAAGAATGATGATTTGCTAAAAAATCAGgaaaaagaatttgtaatcagtaataatgaaaatgaattaattccGTTAAGTGTGCAAGAAATCATTAAGAAGACTACTTCAAGAACAAAAACACACTTTATGGAGATACCAAAATTGGAtgttaaaatgattttGTCCAAGAAAATTAATGATCGTATATCAAATTCGATGAACGATAAAAATAGTCATCCAGATATATGTAATACTGATCACACAAGTAATAAAGACGAACCTAAAGTGATGTTTGTACCGAATATTACCAATGTTAATGCTAATGTGacGCAAAAATCACAATCAAAAGTATGTCAATTTTGtgggaaaatatttaaaaagaacgcTGATCTTGAAAGACACAAAAGAATACATACTGGCGATAAACCGTATAAGTGTGATAATCAGGATTGTAATAAAGCATTTGCCACTAAATATTCACTCGAGTATCATGTACTTACTCATTTGGGTAAAATGAAACGTGCCGTATGTCCCCAGTGTAACGGATTATTTGCCACCATGTCGTCTATGAAAGTTCACATGCGGCAACATACAggCGAAAAACCATTTAAATGTCCTGTTTGTGGTGACGCGTTTCGAACATCTGGgcatttacacacacacgtaataatccacgaacgaaaaaataaacggaaatga
Protein Sequence
MDDQMVLENAESQFITLSDVGESMDSRAAEQLSNQYTPIVLDSDNCQDVSDMYPLNDLLVGETFIIETSERPIIVNGNQFISFQKLNCDRQIDKFDNVQTISTVELEKSADRIKFRINSTDSFQDTCTNSNKTNSNDIVKTTHASSNLKNHSEISIDTDIDTTGGNYSNSVAIKILDDVAKSPIDTNGHFVCDLCLHEFHNWRNYKKHKLEHLNDKPFKCLKCLKSFNYNTNYLLHIASHSTNNLKCPQCKKEFKRVASFKSHLKIHKIEESITCNICYKIFDNQYRLDIHKEHCMQENIISLDNPTKLSCFKTCKTCKISILTVSEYKVHIKEHKKFNSVLRKQYKRTTKLKKSHKTSNLNKRFKCEHLNCDWSFNKLNLLIRHMRTHTGEKPFKCSYCSSLFSQKSSLNRHLLRHKGLRPFSCEFCKMTFSQKGHLINHLKRCHAVTKEITRNHKCSMCSCTYITLSALNKHLSAYHGLKIKKSNKNVKKNIPKSVKVDDINETINLIKDSSNLETLLGEVTRELQNSDSNTKSKKHCDTVSTQCNFELNSINNEDCDHIDNSFSSNIKSTSYQMDIENLTNSPQNDEHIMVSQNKDEQSFGKNDDLLKNQEKEFVISNNENELIPLSVQEIIKKTTSRTKTHFMEIPKLDVKMILSKKINDRISNSMNDKNSHPDICNTDHTSNKDEPKVMFVPNITNVNANVTQKSQSKVCQFCGKIFKKNADLERHKRIHTGDKPYKCDNQDCNKAFATKYSLEYHVLTHLGKMKRAVCPQCNGLFATMSSMKVHMRQHTGEKPFKCPVCGDAFRTSGHLHTHVIIHERKNKRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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