Basic Information

Insect: Cetonia aurata
Gene Symbol: ZEB1
Assembly: GCA_949128085.1
Location: OX421882.1:4145610-4149128[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.00033 0.061 15.4 3.2 2 23 67 88 67 88 0.98

2 18 2.2 4e+02 3.4 2.7 1 23 92 114 92 114 0.93

3 18 0.086 16 7.8 0.2 1 23 148 170 148 170 0.88

4 18 0.0021 0.39 12.8 3.3 1 23 177 200 177 200 0.96

5 18 4.2e-05 0.0076 18.2 0.5 2 23 212 234 211 234 0.97

6 18 1.5e-05 0.0028 19.6 5.0 2 23 242 263 241 263 0.97

7 18 2.1e-06 0.00038 22.3 0.4 1 23 269 291 269 291 0.97

8 18 6e-06 0.0011 20.9 3.7 1 23 297 319 297 319 0.98

9 18 0.00091 0.17 14.0 2.0 2 23 339 360 339 360 0.98

10 18 2.2 4e+02 3.3 3.5 1 23 364 386 364 386 0.95

11 18 1.3 2.3e+02 4.1 0.9 1 23 391 414 391 414 0.93

12 18 0.033 6 9.1 0.3 1 23 420 442 420 442 0.89

13 18 0.0052 0.96 11.6 4.0 1 23 449 472 449 472 0.94

14 18 0.00013 0.024 16.7 0.5 2 23 484 506 483 506 0.97

15 18 1.5e-05 0.0028 19.6 5.0 2 23 514 535 513 535 0.97

16 18 0.00057 0.11 14.6 1.7 1 23 541 563 541 563 0.96

17 18 1.5e-05 0.0027 19.6 3.6 1 23 569 591 569 591 0.98

18 18 1.7e-05 0.0032 19.4 0.2 1 22 597 618 597 618 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.00033	0.061	15.4	3.2	2	23	67	88	67	88	0.98
2	18	2.2	4e+02	3.4	2.7	1	23	92	114	92	114	0.93
3	18	0.086	16	7.8	0.2	1	23	148	170	148	170	0.88
4	18	0.0021	0.39	12.8	3.3	1	23	177	200	177	200	0.96
5	18	4.2e-05	0.0076	18.2	0.5	2	23	212	234	211	234	0.97
6	18	1.5e-05	0.0028	19.6	5.0	2	23	242	263	241	263	0.97
7	18	2.1e-06	0.00038	22.3	0.4	1	23	269	291	269	291	0.97
8	18	6e-06	0.0011	20.9	3.7	1	23	297	319	297	319	0.98
9	18	0.00091	0.17	14.0	2.0	2	23	339	360	339	360	0.98
10	18	2.2	4e+02	3.3	3.5	1	23	364	386	364	386	0.95
11	18	1.3	2.3e+02	4.1	0.9	1	23	391	414	391	414	0.93
12	18	0.033	6	9.1	0.3	1	23	420	442	420	442	0.89
13	18	0.0052	0.96	11.6	4.0	1	23	449	472	449	472	0.94
14	18	0.00013	0.024	16.7	0.5	2	23	484	506	483	506	0.97
15	18	1.5e-05	0.0028	19.6	5.0	2	23	514	535	513	535	0.97
16	18	0.00057	0.11	14.6	1.7	1	23	541	563	541	563	0.96
17	18	1.5e-05	0.0027	19.6	3.6	1	23	569	591	569	591	0.98
18	18	1.7e-05	0.0032	19.4	0.2	1	22	597	618	597	618	0.96

Sequence Information

Coding Sequence: ATGGAAAAGGTACTTTACCTGAAACAGTCTATTCCGATATTAAATTccaatttaaacatttttggtCCATCATACACATTGTGTGACTCCATCCGTGGACACACCATATTTAAGAGAAGTGGTGGTACCGACTGTACTAAGGTAGGACCAAAAGTTGAAATGTTACTGACAATGCCGAAACGAAAAAAGGTGTGGCGCAGATGCACCATTTGCCATCAGAACTTCACGAATCTAGAATCTCTAGAGACCCATTTCCAAACTCACGACTTTAAATACGACTGCGGGATGTGCTCAGAGCGTTTCCGATGCCTCTATCAATTTTCCATCCACACGAGCGAGCATGACGATCAGAATTACACGTGCAGCGCTTGCAGTTATTGGACGGATAAAAAGAACAGCCTCCTGATACACGTGCACAACGTCCACCTGAAGAATTTCTTGTACTATTGCGGAGTGTGTCGCAAGGGTTTCAATAGCAACTGGGATAAACTCGAACACGAAGCTTTGCACGACGGCGAGAAGAAGCCGTATGCCTGCGTGGTGTGCCAGCACAAGTTTTCCTACTCCAAGAACTTGCTTTCGCATCAGACGAAGTACCACAGCGCCATGGTGACCGGTGCTTATTTGAAGAACCAATGCTCGGTGTGCAAGAAGATCTTCGGGAAGAAAGCCACGTTGGAGAACCATATTCGGATCAGTCACGATTTAAAGCTGAAGCCCCAGATGTGCGATAAATGCGGTAAATGTTTTCCGAACAACCACAAGCTGGAACTGCACTACAGGACTCATACGGGTTTTAAACCGTTCGCTTGCGAAACTTGCGGGAAATCTTTCAGGACGAAGTATCTCTTAGGGGAGCACGTTCGGATACATACCGGCGAGAAGCCTTTCGTGTGCAAATTTTGCGGGAAATGCTTCAACCAGAGGTCTCCTTTGAAAGTCCACACTCGAttgcataccggtgaaaagccGAAAACTACGACTCAGAAAAAGCCGAAACGAAAGAAATTCCGCAGATGCACGATTTGCCATCAAACCTTCGCCAAAATAGAAGACCTAGAGACCCATTTTCAAACTCACGACTTCAAATACGACTGCGGGATGTGCTCGGAGCGTTTCCGATGCCTCTATCAATATTCCATCCATACCAGCAAGCATAACGATCAGAACTTCACGTGCAGCGCTTGCAGCTATTGGACGGACAATAGGAGTAACCTCCTGTTGCACATACACAACGTCCATTTGAAGAATTTCCTATATTATTGCGGGATATGCAGGAAGGGTTTCAATAGCAAATGGGACAAGCTCGAACACGAAGCTTTGCATAACAGCGAAAAGAAGCCACACGCCTGCGTGGTGTGCCAGCATAAGTTTTCTTACTCCAAGAACTTGCTTTCGCATCAGATACGGTACCATAACGCCATGGTGACAGGCACTTACTTGGAAAATCAATGCTCGGTGTGCAAGAAGATCTTCGGAAAGAAAGCCACGTTGGAGAACCACGTCCGGGTCAACCAcgatctaaaattgaaaccgcAGATGTGCGATAAGTGTGGAAAATGTTTCCCGAACAACCACAAACTGGAACTGCATTACAGGACCCATACCGGGTTTAAGCCGTTCGCTTGCGATGCGTGTAAGAAATGCTTCAGGACCAAACAGCTGCTGGACGAGCACGCCCGGATACATACGGGCGAAAAACCTTACGCCTGCAAATTCTGCGGGAAATGCTTCAACCAGAGAACTCCTTTGAAGGTCCATACTCGCATGCATACCGGGGAGAAACCTTACGTGTGCCAGATCTGTACTAAAGGCTTCACGTCCAAAGGAGCCCTTACCATACACACTCGGCGCTGTGATGGTAATAAAGTAAAGAAGGAAGGTTCGAAAGATGAATCAGACGGTTAA
Protein Sequence: MEKVLYLKQSIPILNSNLNIFGPSYTLCDSIRGHTIFKRSGGTDCTKVGPKVEMLLTMPKRKKVWRRCTICHQNFTNLESLETHFQTHDFKYDCGMCSERFRCLYQFSIHTSEHDDQNYTCSACSYWTDKKNSLLIHVHNVHLKNFLYYCGVCRKGFNSNWDKLEHEALHDGEKKPYACVVCQHKFSYSKNLLSHQTKYHSAMVTGAYLKNQCSVCKKIFGKKATLENHIRISHDLKLKPQMCDKCGKCFPNNHKLELHYRTHTGFKPFACETCGKSFRTKYLLGEHVRIHTGEKPFVCKFCGKCFNQRSPLKVHTRLHTGEKPKTTTQKKPKRKKFRRCTICHQTFAKIEDLETHFQTHDFKYDCGMCSERFRCLYQYSIHTSKHNDQNFTCSACSYWTDNRSNLLLHIHNVHLKNFLYYCGICRKGFNSKWDKLEHEALHNSEKKPHACVVCQHKFSYSKNLLSHQIRYHNAMVTGTYLENQCSVCKKIFGKKATLENHVRVNHDLKLKPQMCDKCGKCFPNNHKLELHYRTHTGFKPFACDACKKCFRTKQLLDEHARIHTGEKPYACKFCGKCFNQRTPLKVHTRMHTGEKPYVCQICTKGFTSKGALTIHTRRCDGNKVKKEGSKDESDG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -