Basic Information

Gene Symbol
-
Assembly
GCA_963169105.1
Location
OY720635.1:56893965-56913344[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.1 1e+03 3.4 0.0 3 23 71 93 69 93 0.89
2 16 7.9e-05 0.074 16.5 0.8 1 23 99 122 99 122 0.97
3 16 5.3 5e+03 1.3 1.1 2 17 451 466 451 467 0.80
4 16 2.9 2.7e+03 2.1 3.5 1 23 504 526 504 527 0.90
5 16 0.29 2.7e+02 5.3 0.1 2 21 533 551 532 552 0.93
6 16 3.2 3e+03 2.0 1.5 1 20 580 599 580 601 0.88
7 16 1.3 1.2e+03 3.2 0.4 6 23 637 654 632 655 0.91
8 16 4.8 4.5e+03 1.4 0.3 2 22 661 680 660 680 0.87
9 16 5.9e-05 0.055 16.9 1.6 2 23 698 719 698 719 0.98
10 16 0.15 1.4e+02 6.2 0.6 2 20 728 746 727 746 0.94
11 16 2.9e-07 0.00027 24.2 0.6 1 23 768 790 768 790 0.99
12 16 0.015 14 9.3 0.2 1 23 796 818 796 818 0.95
13 16 9.6e-07 0.00089 22.5 3.5 1 23 824 846 824 846 0.98
14 16 0.068 63 7.2 0.3 1 13 879 891 879 901 0.83
15 16 0.0015 1.4 12.5 0.1 1 23 907 929 907 929 0.96
16 16 0.12 1.1e+02 6.5 0.0 1 21 972 992 972 993 0.92

Sequence Information

Coding Sequence
ATGACCCTTTActtcattttgtcttttttaattaGTGCACCTGGGGATTTGGGCAGTAAGACAGACGGCAAACCAGTTGATGAGCTGCCAGTGGGAGCAGCGAAGGCAGAGGAGGTGAAAGAGGTGGAGCCAGCTGATGAGTATGAGCTCACTGTGACAGAAGAGTCGCTGGTGCGTCTCCACGGCCTCTCGCTTGACCTCCCAGTCCCCTGTGATCTGTGTCCCATCGGCACGGTGTTTGACGACCTGGATGAGTTTGATGCCCACATGAGTGAGCACCTTGAGGCCAAGATGTTTGCATGTCAGCTGTGTAGCAATACATACAGGTCGTGGTCTAACCTTGTGGCCCACCGTAAGACGTTCCACTTGGGTGAGGTGCTGAGCTGCGAGACGTGTGGCTCGAACAAGACCCACACAAGGCTTGAGGGTGCTGTTCACTTCCCGGTCAAAGGCAAGCCTCATGGTTGTGAGGAGTGTCGGATTGGCCTGGACACCATCTCGGATGTTTATCAGCACTTTGTCGAACACAAAGCCCCTCCATGTGGTAGCCAACAGAGGTCCTTTAAACATTCGAGGCCTTCTAGGAAGAGGAAAAGATCTACTAAGGCAAAGAGTGGCGTACAAAATCAGAAGAAGAGTGTGGAAATGAGCCCGTCTTTGAAATTGAATGGTGGCTCTGGGGAATGTGTAAACGTTCCTGTTTGTCCAGTTGGTGGAAATCCTTCCGAGAACATAATTGGGAGTGTGTTATTGATTCCCAGTGGAACTTCATTGGGGAATCTGCCTGGAATTAATGGCGGGAATCTAGTCTTGATGCCTGCTGTGATTCAAGGCAGTAGTTTAATAGGGAATCCGATTGAAAGTCAAAGCGAGAGGAAAGAGTCTGTTGAGGTGACTAAGACTAAGATTAGTGGTGGGGACGTGAGTGTGAATCCTCTTAGTTTACTTAGTGGAGACTTGACTGATAATCAACAAGGACCTTCGAATACAAAGTTGATTGGGGATCTTGCTGACTTAGGAAAAGAGATAGCTACTGAGAATGCTGCTGCGGTTGAGCAACCTAATCCACCTTTGAATCCCACCCAAACTCAGAGTGAAGTCTCAAGTGGTCATAGTGATAatgagaatgaaagtgaaaatctGATTATGGACCTACCTGAGATTCCGAGTGAAATATTGGATGCAACACCTGCTGAGGAACTAAAGAGCTGTCCTGTCAAGAGTAGGAGTAGAATTGATGCTGTAAAGAagccaagagaaaggaaaagacCCAAACGACTGAAGGATCCAGTATTGAGCCGAAGAGGTATGCTCGAAGGAAATAAAGGATTGGTTAAAAGATCGAAGCGATCATGCCCTCATTGCGAATGCTCATATGTAAAATTGGTGGACTATCGGAAACCATTATTCCGTGAATCAGAAGTCCACGATTGTGTCATGTGCTCTAGCCATCATCTCAAGAAATTGTTAACGAAAGACCATGAATATTGTCCGGCCAAATCTCAGCGATTCCATTGCTTTCCCTGCAAGATGGGCTTTAAGTCAGATTCTGAGTTTGCCACACACCTGAGTGAACATCACGCCCAAGGTCCCCTTCCTTGTTGCGTATGCGGCAGGAAAGTCAACTCAAATCAGTTAGTGGACCACATTAGAGCCTGCCAGCAGAAATGCATTGAATGGGATTTACGGAAGCGGCAGATCAGCCAAGGAAATGAAGGAATAGTTGAAGCAGCAAAGCACTTCTGCCCTCATTGCAACTCCTCCTACTTAAAATTGGCGGATTACCGGAAACATTTGGTTCGTGCTTCAGAACTCCATGACTGCGTCATGTGTTCTCATCTCGAGAAATTTTTGACTGAAGATCATGAATACTGCCAGACCAAAACCCAGCAGTTCCGCTGCATTCCCTGTGGGAGTGTCTTTGATTCAGATGCTGAGTTTACCACCCACCTGAACGAACATCATACTCAAGATCCCCTTCCTTGTTGCCTATGCGGCAGGAAAGTTGACTCGAATCTCTATGTGGATCACATTAAAACCTGCCAGAAGAAATGCATCGAGTGGGAGTTGGAGAAGCAGCCGATCATCAGGACTTGCGACCAGTGTGGGAAGATGTTCAACTCCATCAGCTCAATACGTAAACATTTGAAGAGGCACGAGCTCAACCGCAAGATCTCGTTGTACTGTGGGACGTGCGAGAGGATGTTCCAGCACAGGGGGGCGTACTCAAAGCACCTTTGGGCCAACCCCACTCATGGGCCTCCTGAGCACCGAGCCAGATATCCTGGCACATGCACTGACTATGTCTGCGAAAAATGTGGCAAGACTTTCGCAAAGCGTGGTGCTCTCAAGTTGCACCTGAGGAAACATGATGGTCTGAGGCCATATGCATGCCCAAGCTGTCCCAAATCATTTATTAGTGGGACAGCACTGTCATTCCATGTCCGGAGGCACACTGGTGATCGCCCATACATGTGTGAGATTTGTGGGAAAAGCTTCACAATGCAAAAGTCTTTGCATACTCACCAGAAGACCCACCAGGATGGGGAGAAGAAAGTTTTGAACAGGAGAATCCGTTCTGAAAACACCAAGCCAACCATCAGGAAGATCAACAACAATCCAAATGCCAAACGGTACCAGTGTCCTGTCTGTGGCAAGATCCTTTCATCCAAGCTGATATACGATGGTCATGTGCGGCACCATACTGGGGAGCGCCCTTATCCATGTGATATATGCGGTCGAGCATTCACCTTGGCGAAGGTCATGAAGCTGCACCGCAAGGGACATGCAAAGGGTCGGGCTGAGAATAAAATTCCACCTGTGACCTGGACCCATGATACTTCAGACTTGGAAAACAAGGTAGTGATACATCCTGAGGGAGTTTTTGAGGGAAACCCCTTGGAAACTTGCATCTACCTTTGTCCTCGATGTGGTGTGGGTGTGGTGTCTCCGGGTGAGTTGGAGGAACACTTGTCCAAAGGTGCTTGCCTCGGTcgcacacctatcctcccgcctccgtctgGCTTCCGCCCGCTTCCTCCCGAAATTTCCGAAGGATGGGCATTCTACGCCGTCCGCCGAAACCGAACGACGATAGACATGGGCCCGCAATACCTCAAAAAGAAGGAAAGCGATTCACCGCTTCGTTTCCACTACAATCGGTTACAAATTTCTGTGCAAGCAAACAGTAGACTACGACTCAAGGGGGCGACTCGACTTGTGACCCCCTCCGTCGAGGGCAGCCCCCGGCAACTCCCTATCCTTGCCGTGTTGGCTCCGCTCTCCCTTATTGTCCGATTAGTTCCTGCTTTGGTCGTTGGCGCTACTTGTGCAGTCGCCCGACAAAAGCCCGATGACATCCCAGAAATTTGGGTATGGGAGGGGCTGGTTAAAGAAGGGACGGGAGGGAAGTGGCGAGGTGGAGAGCGGTCGGGCGAGGAGGATCATGGAGTCGTCGGAGGGAAGGGGAGCGGCGGGGAGTGGTGGGGACAGACGAGGAATTTACCAATTTTGGGGATGAATGAAGGGCAGTGGTGGCTGTTGACTTCAGGGGACGAGGGGTCGGGGCAGGAGTCGAAACGGTTGAAATACGTGAACTACGAATTTTGA
Protein Sequence
MTLYFILSFLISAPGDLGSKTDGKPVDELPVGAAKAEEVKEVEPADEYELTVTEESLVRLHGLSLDLPVPCDLCPIGTVFDDLDEFDAHMSEHLEAKMFACQLCSNTYRSWSNLVAHRKTFHLGEVLSCETCGSNKTHTRLEGAVHFPVKGKPHGCEECRIGLDTISDVYQHFVEHKAPPCGSQQRSFKHSRPSRKRKRSTKAKSGVQNQKKSVEMSPSLKLNGGSGECVNVPVCPVGGNPSENIIGSVLLIPSGTSLGNLPGINGGNLVLMPAVIQGSSLIGNPIESQSERKESVEVTKTKISGGDVSVNPLSLLSGDLTDNQQGPSNTKLIGDLADLGKEIATENAAAVEQPNPPLNPTQTQSEVSSGHSDNENESENLIMDLPEIPSEILDATPAEELKSCPVKSRSRIDAVKKPRERKRPKRLKDPVLSRRGMLEGNKGLVKRSKRSCPHCECSYVKLVDYRKPLFRESEVHDCVMCSSHHLKKLLTKDHEYCPAKSQRFHCFPCKMGFKSDSEFATHLSEHHAQGPLPCCVCGRKVNSNQLVDHIRACQQKCIEWDLRKRQISQGNEGIVEAAKHFCPHCNSSYLKLADYRKHLVRASELHDCVMCSHLEKFLTEDHEYCQTKTQQFRCIPCGSVFDSDAEFTTHLNEHHTQDPLPCCLCGRKVDSNLYVDHIKTCQKKCIEWELEKQPIIRTCDQCGKMFNSISSIRKHLKRHELNRKISLYCGTCERMFQHRGAYSKHLWANPTHGPPEHRARYPGTCTDYVCEKCGKTFAKRGALKLHLRKHDGLRPYACPSCPKSFISGTALSFHVRRHTGDRPYMCEICGKSFTMQKSLHTHQKTHQDGEKKVLNRRIRSENTKPTIRKINNNPNAKRYQCPVCGKILSSKLIYDGHVRHHTGERPYPCDICGRAFTLAKVMKLHRKGHAKGRAENKIPPVTWTHDTSDLENKVVIHPEGVFEGNPLETCIYLCPRCGVGVVSPGELEEHLSKGACLGRTPILPPPSGFRPLPPEISEGWAFYAVRRNRTTIDMGPQYLKKKESDSPLRFHYNRLQISVQANSRLRLKGATRLVTPSVEGSPRQLPILAVLAPLSLIVRLVPALVVGATCAVARQKPDDIPEIWVWEGLVKEGTGGKWRGGERSGEEDHGVVGGKGSGGEWWGQTRNLPILGMNEGQWWLLTSGDEGSGQESKRLKYVNYEF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-