Basic Information

Gene Symbol
-
Assembly
GCA_026724355.1
Location
JAKKRE010000039.1:127236-129826[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 3.3 4e+02 2.3 0.0 10 22 4 16 2 16 0.89
2 14 6.6e-05 0.0081 17.1 1.8 1 22 21 42 21 42 0.97
3 14 0.00014 0.017 16.1 0.5 1 23 205 228 205 228 0.95
4 14 3.4 4.1e+02 2.3 0.9 9 23 237 251 236 251 0.93
5 14 0.00014 0.017 16.1 3.0 2 23 388 410 387 410 0.97
6 14 0.078 9.5 7.5 0.1 3 19 450 466 448 469 0.92
7 14 0.021 2.6 9.3 4.3 2 23 477 499 476 499 0.92
8 14 0.0049 0.6 11.2 4.7 1 23 510 533 510 533 0.91
9 14 7.6e-05 0.0092 16.9 0.1 1 21 570 590 570 591 0.95
10 14 0.0053 0.65 11.1 0.5 2 23 599 621 598 621 0.92
11 14 5.6 6.9e+02 1.6 9.8 2 23 630 652 629 652 0.96
12 14 0.018 2.3 9.4 0.5 2 20 686 704 685 706 0.93
13 14 0.0021 0.25 12.4 0.7 2 23 722 744 721 744 0.92
14 14 1.8 2.2e+02 3.2 0.2 2 11 807 816 806 820 0.88

Sequence Information

Coding Sequence
ATGACGGACTTCAAAAATGATTACTCGCTCCAAGCCCACATTAGGGTGTGGTCTGGTAAATACAAATGTGATCAATGTAACGCTACGTTCTGCACACTAAGCGGACTGCAGATGCATCAGAGGCGCGGCTGTGACATAAAATCTAATGTTCCGTGTAACTACATGTTTTGTAACTTTTGTAACGCAGAACTGAAATGGAAGACCAGTTTGCAAAGTCATTTATTCCACGTTCATGGAGATTTGATACATTCTGGTAAGAACGGAGATGAAGACGCATCAGTAAGATCCAATGACCTCACTAATTTCAGCGATACACCACTCGCAGAGGAGTTAGCCCCTCCTAGGAAGAGAAGGAAAATTTGTCAGAGTATAGGAAATTCAAGCCCCCTGGTCTTCAAAGTGTCAAATTCGTCGTCAACTGACACTTTAAAAGACAAATTAGAGAAATGTAAAGAATGTATAGTTCTAATCAAGCGATGCGACTCGATTGTAAAGAGTATTAAGTTAGGCGAAAACATTTCTCTGCGAGTAGATCTGAAAGAGACAATGCATTTACCCAGCAATGCTTACTCAGCATCTTCTGATCTCCCTTTAGCCAAGTGCGTCAACGCATATAAATGTAGTCGTTGTGAAAAAGCATTTCCCTTGAAGAAGGAAATGAAGAAGCATATGATAGCAGTTCACTTGACATCGACCAATTACACTGCTCGTTACAAGTCTAAGAAGATGCTGTTCCAACATTATATGCGTCACAGTAGCATTCTTTTCAAAGACAGACAGAAATTTAATATAAGTAAGAAGCTTCACCAGTGCGCAGGCTGTTGCAAGCGATTTTGGCTACGTTCATGCTTGGAGCAGCATGAAAAGGTATGTAGGATTGCTCAGAGATCTCGTGCATCAGCCTTGGAAAGCTCTAAAGACGAAACAGCAAAGGTATTCGATGAAAATCAAGATTCCTCAGAATTATCTGAGGGCACATTCAAACGAAACAGAAGTGCAAAAATACGCTGTATAGAGAACATGAAAAACCTACTAGATACTAAGGATACATTCGTAATAAAAACGAGGTGGACGAGCTCCGTCCATTGCTCCGTTTGTGGACAATTTAGAAATTTGAATAAAAAGTGCATGCACAAAATCTTATTCAAACATTCCAAAATTAGGTGCGACATTTGTCATCAGGCATTTGCCAGTACAAAAATGTTGAAATCACACATGTGTACAATTCACAAGTATAACTCTTTGGATAATTATTTTCGCAAGAACTCAAATCAAAAAGATGTTCAAGTGCACCACGTCGACACCGACGCTATGTCAGTGACGAATACTTTGAATGTGAACGTAATTTGCAATGTATGCAATCTAGCATTTCAATCGTATGACCAATTTAGAGATCATAATATGTACTACTACCAAGATCAATCATTAGAGTGCAGTGTTTGCGGTAAATCGTTCCATGGGATGTATCAACTACATCACCATAACAAATTAGAACATTATCCCGCTAAATTGCGAGATTTGTACACTTACAAGTGTAGCATTTGCGAGGAAGGTTTTAATTACGAGTCGCACTTGCATGCACATAAATTTCATGTTCATCCGGACGGTATAATAGTCGATATGAACATCAAGCACGACCACATCTACACGTTGGCAACGAACATCATCACGATGTCAGAAAATATAGCATCGATACCAATGAAAACGTATATGTGCGATGTCTGCGACTTGCAATTTACCAACAAAGAAGATCTGAAAGAGCATCAACTGGAGTATTCGAATAATGGCGAGATTTATTGTAAAAGGTGTACCAAGAGCTACAACACGATCGCTGCACTCGCCAAGCATTACAGTCTGAATCACTCCGGGTCTGTCCCAAACATTATGAGGTGTTGTCATTGTAACGAGGCGTTGACGACTAACACGTCGCTGCAGTGTCACATGAGACATTTTCACGGGAGCAACTCCACTCAAAATGTAGCGAAGAAGAGGGAAAGAAATTCTTGTATGAAATTTAATGGCGGCCTCGTCGAGTTTAGTAAACATGTCGGTGATACCTGTGCGACATGCAACACGAAATTCGATCACACGGTTAGTTTGAGGAATCATTTGTTAGAGTATTCGAACATAGGATCGTACGACTGTATCCAGGGATTCTCCTGTTATTGCCCGATATGTAACGAGGGATTCACGGATTCCGCGTTGGTCCGCATCCACGTGTTACATCTTCATTCATACGAGTCTTTCGGCTTGATCCAAAATACCCTCGAGACGAGTCTTGACTTGTGCGGTGCTCCTGAAAGCATTGATTCTAAGGACAATATCGTCCCATTGGTCAATGATAGCTCTGATGTTAATAAGAATATAAACTCTGATGTTAATAAGATTATAAGCTCTGATGTTAATGAGAATGTACTAAAATGTCCCAAGTGTGACTTGGAGTTCAACGGCGGTAAAAATATACAGAGCACAGGAGTTGTTACGAATGCTCAGGTTGCAGTTATAGATTTCCTTCATCGTCTTTGA
Protein Sequence
MTDFKNDYSLQAHIRVWSGKYKCDQCNATFCTLSGLQMHQRRGCDIKSNVPCNYMFCNFCNAELKWKTSLQSHLFHVHGDLIHSGKNGDEDASVRSNDLTNFSDTPLAEELAPPRKRRKICQSIGNSSPLVFKVSNSSSTDTLKDKLEKCKECIVLIKRCDSIVKSIKLGENISLRVDLKETMHLPSNAYSASSDLPLAKCVNAYKCSRCEKAFPLKKEMKKHMIAVHLTSTNYTARYKSKKMLFQHYMRHSSILFKDRQKFNISKKLHQCAGCCKRFWLRSCLEQHEKVCRIAQRSRASALESSKDETAKVFDENQDSSELSEGTFKRNRSAKIRCIENMKNLLDTKDTFVIKTRWTSSVHCSVCGQFRNLNKKCMHKILFKHSKIRCDICHQAFASTKMLKSHMCTIHKYNSLDNYFRKNSNQKDVQVHHVDTDAMSVTNTLNVNVICNVCNLAFQSYDQFRDHNMYYYQDQSLECSVCGKSFHGMYQLHHHNKLEHYPAKLRDLYTYKCSICEEGFNYESHLHAHKFHVHPDGIIVDMNIKHDHIYTLATNIITMSENIASIPMKTYMCDVCDLQFTNKEDLKEHQLEYSNNGEIYCKRCTKSYNTIAALAKHYSLNHSGSVPNIMRCCHCNEALTTNTSLQCHMRHFHGSNSTQNVAKKRERNSCMKFNGGLVEFSKHVGDTCATCNTKFDHTVSLRNHLLEYSNIGSYDCIQGFSCYCPICNEGFTDSALVRIHVLHLHSYESFGLIQNTLETSLDLCGAPESIDSKDNIVPLVNDSSDVNKNINSDVNKIISSDVNENVLKCPKCDLEFNGGKNIQSTGVVTNAQVAVIDFLHRL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00303404;
90% Identity
-
80% Identity
-