Basic Information

Insect: Ceratina calcarata
Gene Symbol: Zfhx4
Assembly: GCA_026724355.1
Location: JAKKRE010000004.1:6310427-6320806[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 7.2 8.8e+02 1.3 0.8 2 20 223 241 222 246 0.88

2 15 3.7 4.5e+02 2.2 1.5 1 23 270 294 270 294 0.91

3 15 0.055 6.8 7.9 0.1 2 23 387 409 386 409 0.95

4 15 0.096 12 7.2 0.1 3 23 431 452 430 452 0.95

5 15 0.0037 0.46 11.6 1.3 1 23 536 558 536 558 0.97

6 15 0.00016 0.019 16.0 0.2 2 23 565 587 564 587 0.95

7 15 0.0021 0.26 12.4 3.3 1 23 677 701 677 701 0.91

8 15 0.006 0.73 11.0 0.6 1 22 721 742 721 745 0.89

9 15 0.0008 0.098 13.7 0.2 1 23 786 810 786 810 0.93

10 15 0.23 28 6.0 0.1 2 21 859 878 858 879 0.93

11 15 0.18 22 6.3 2.0 2 19 1026 1043 1025 1048 0.91

12 15 0.00013 0.016 16.2 2.5 1 23 1638 1660 1638 1660 0.99

13 15 0.0041 0.5 11.5 0.5 1 23 1767 1789 1767 1789 0.98

14 15 0.012 1.4 10.1 0.3 2 23 1932 1954 1931 1954 0.95

15 15 5.8 7.1e+02 1.6 0.3 2 21 2233 2252 2232 2256 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	7.2	8.8e+02	1.3	0.8	2	20	223	241	222	246	0.88
2	15	3.7	4.5e+02	2.2	1.5	1	23	270	294	270	294	0.91
3	15	0.055	6.8	7.9	0.1	2	23	387	409	386	409	0.95
4	15	0.096	12	7.2	0.1	3	23	431	452	430	452	0.95
5	15	0.0037	0.46	11.6	1.3	1	23	536	558	536	558	0.97
6	15	0.00016	0.019	16.0	0.2	2	23	565	587	564	587	0.95
7	15	0.0021	0.26	12.4	3.3	1	23	677	701	677	701	0.91
8	15	0.006	0.73	11.0	0.6	1	22	721	742	721	745	0.89
9	15	0.0008	0.098	13.7	0.2	1	23	786	810	786	810	0.93
10	15	0.23	28	6.0	0.1	2	21	859	878	858	879	0.93
11	15	0.18	22	6.3	2.0	2	19	1026	1043	1025	1048	0.91
12	15	0.00013	0.016	16.2	2.5	1	23	1638	1660	1638	1660	0.99
13	15	0.0041	0.5	11.5	0.5	1	23	1767	1789	1767	1789	0.98
14	15	0.012	1.4	10.1	0.3	2	23	1932	1954	1931	1954	0.95
15	15	5.8	7.1e+02	1.6	0.3	2	21	2233	2252	2232	2256	0.88

Sequence Information

Coding Sequence: atgctggtgctgcagcagaacgtgaagcacatgcagactctatccgcgctccagtcgcaccatcaacaggcgcagcatcaccatcagcaggcacagcagcagcaccaacagcaacaactcgaacaattattacatttgggcggcctggacaaaccTCAACACGCGGAAGCCGCTCTGGCCGACATGGCGTATAACCAGGCGCTGCTTATTCAGATGATGACCGGCGGCCAGCTACCGCCGCAGCTTCCGCCGGAGATCATGGGTGGCATGGCGAGCATGGGTGCCATGGGCAACCTTGGCGGCGACGTCGGCTTGTCGCCCGACAGTATGGATCCACCACCGGAGCCGGCAGACCCGGATCCCTCTCATTTGTACCACTGTTGCGTATGCAACAACTTCGCGACGGACTCGCTCGAAGCCCTCGGCCATCATTTGGCCGTCGATCGGACGAGGACGCGTGAGGGCGAGATCCTAGCGCTGGTCGCCGGCCACTTCGTCTGCAAACTCTGTTCCTACAAGACCAACCTGAAGGCGAACTTCCAGCTGCACTGCAAGACCGACAAGCATCTCCAACGTCTGCAACATGTGAACCACGTGAAGGAGGGCGGACTTAGGAACGAATGGAAGCTGAAGTACCTGGCGTCGCCCACGAGCGCCGCGCAATTGCGTTGCCACGCGTGCGACTATTACACGAACAGCGCTCACAAACTCGCGCTTCACGCGGCTTCTCCCAGGCACGAGGCAGCCGCGCTTCTCCTTCGTCATCTACTCGAGGCAAGCGCGAACGTGCCCTCCCAGGCGAAGCTTTATCACTGCGCGTTGTGCGGGTTCAGCGCGCGTCACCGGCTGCCGCTGCTCCAGCACGTGCGCTCGTTGAGACATCTCCAAATGGAGCAGCTGCACCAGCTTCATCGTCGCAGCGGTATACAGGGCAACGAAACTCCTCACACGGACATCGGTGACGTTTTTCAAGTTATGAGCGACCCCGACGCGCCACCCGCGCAACAATCCAGTCCCACTACGCCGACCACGCCGAATGCTACCAGTGCCAACAATGAACGACGCGAGGAAGGTAGCGACTGCGGCAGCGAGGTGAAGCAGGAACCGGACAACGACCAGGAACCGGAACAAGAGCCAGAGAACGATCAAGACGATGTCAGCTGCCCATATTGCACTTATCAGCCGACGTCGCGCGACGAACTACGGCAACATCTGCAAGTGGCGCACGTCCAGGATGCGGAGGATAAGGCAGAGGCTTGCGTGAAAGAAGAGCCGCCGCCGGAATTATTGTGCCCGTTGTGCCAGGACGGTTTCAAAGAGCGTTCCGCGTTGGAGAAGCACGTGATGCAGATACACTCGGTGAACTCGGACGGATTGCAACGATTGCTATTACTAGTGGATCAGAGCCATTGGTTGAACAACAACCCGAGGAGCACGTCGACGCCGGCCGTGACGACACCCACGTCGCCCACCACGACCACTAAACAACCGGCCGAAGAGGATTTAAGCGAGCGTGGCGCGAACGACGAGATCGAGGAGATCACGCGGGAAACTCATCCGGCTACCACGCCGACGTTAGCAGTCAGCGAGAAACACGTGTACAAGTACCGATGCGGACAGTGCAGCTTGGCGTTCAAAACGTTGGAGAAGCTGCAACAGCACTCGCAGTACCACGCGATCAGGGACGCGACCAAGTGCGCGCTGTGCGGCCGTTCGTTTCGCTCGGTCCAGGCGTTGCAACGGCACTTGGAATCGGCGCACGCGGACTTGCACGAGGACGAGCTCGCGCAGTACAAACAGAGCCTGTTGCACGCGAATCCGCTTTTCCAGGCGCTCACCGAGGAAGCTCTGCGCAGGCAGGGTAACTTAACCGGGGAGCAGAACGTCGAAGACGACGCGAGTAAAGCAGATGAGGAAGAGAGTGACGCGAGCGACTCGTCGCCGTTGCACAAGGAACAGCGACTGCTGGAGGACTACTTAAACAGCCAGCCGGTTGCGGAGGATTCGTATCACGATCCCGGGAGGAAATTCAAGTGTCACCGTTGCAAGGTCGCGTTCACCAGGCAGAGTTATCTGACCGGGCACAATAAGACGCTGCTGCATCGCAAGGGAGAGAAGATGTCCTATCCGATGGAGAAGTATCTGGACCCAAACAGGCCGTATAAGTGCGACGTATGCAAGGAGAGCTTTACGCAGAAGAACATTCTGTTGGTACATTACAACAGCGTGAGCCATTTGCACAAATTGAAACGAGCGATGCAGGAGCAGGGTAATAACAACACGTTAATATCGGTGGTTCCACCGGCGAGTCCGACGGAGTCACCCGACTCGCAGCAAGATCAGGATAAGAAACCGTACAAGTGTAACATCTGCAAAGTGGCTTATTCACAGGGTAGTACTCTGGATATACACATGAGGAGCGTTCTGCATCAGACAAGGGCCAGCAAGCTGCCGGATCTCGCTGCCAGTGGACAATTAGACTTAGCTCGTCCGTTGATCGAACAGCCACCACCTAGCAGTCCGAATAGTCCGCCGGTGAACACCAGTACATCCGGTAATAGCGGAACGATGCTTTCATGTTCACGATGCAGCGCTCTATTCGTCAATCAAGAACAACTCGCCACGCATCAACAGCTCTACTGTATATTCAGTAACCCGTTGGCTTTGTTTCAACAGCTGGCGGCGTCGCAACAGCTCGCCTCGTCCACGCCTTCATCCGCGAAAACGCCGCCACCAACGAGCACCACCCCCGGTCCCCAGCCTCACATGCAACAGAGCACCCAACACTCGACGCAAACGACGCAAGACATACTATCACAACCGCGGCATAAAACATCGCAAATGTACACTCACCTCCTGGAGAGCTTTGGATTCGATCTGGTAATGCAATTCAACGAGAATCATCAAAGGCGTCAACGCAAGGAAGAGGAAGCTGCTGCTGCGCTTCAAGCGCAACAGGAACAGCAGAAGCAGGAGCAACAGAAACAGGCGCTCGCCGCTCAGGCTGCCCGTGAAAGGGAGGAAGAGGCCGAGGAGCACACGGATGACGACGTGATACCGGAACTGACCAGGAGCACCTGTCAGCATTGCAATAAAGAGTTCAGCAGTGTCTGGGTGCTGAAGGCGCACTGCGAGGAGGTGCACCGTGATCTAGTGCCTCGCGAATTTTTAGAGAAGTACGCCCAACAGTTTAAATGTGAGTACGAGAAGAAGAGCGTCGTGGTGACCGCCGCGACGTCATCCTCTACGTCCTCCGGGCCGAGGAGCTCGACGCCGGCCAGCGGCCAACCACAGGATCTCACTTCGGACAAGGAACAACGTGATAAGGAGAAGGAGGAAACAGTTGAGAACAAAGATCGCGTCAGCAAGACTCCGGAGGCTACGTCAACGACTCCAGCAACGACTCCAGCACTCAGTAACACGCCTgtctccagcaccgattcagcgactcctacggtgttaccgacgaattcatcgcaacatcttcagcaacagcagcaacagcaacaacaacaacaacagcaacatgctcagcttactctggcccagcaaatgaccgaaatacaagccgcgttcaatgccatggctgcgtcgcagctgcaacaacagcttcagcaataccccgggctcatgatgggcatGATGGGACTACCGCTCGGACTGAACGTCCCCGCTCTGGCTGCCATGAATTTGCAACCACCACTGGTACCGATGATGTTACCACCCCCGCCGTACGATGGAACCGCCACCGGATATCCGCCGATCAACGCCCAGGCTGATCTTCTGGCCAAACAGCATCTCGCCTTGCAGCAACAACAAGCAGCAGCCGCAAACGCGGCTGCCTCGCAGAAACGAGCGCGTACGCGCATTACCGACGAACAGCTAAAGATATTGCGCGCCCATTTCGACATCAACAATTCTCCCGGCGAGGAGCAGATACTAGACATGGCGGCGCAGAGTGGTCTGCCACCAAAGGTGATCAAGCACTGGTTCAGGAACACATTATTCAAAGAGAGGCAGCGTAACAAGGACAGCCCGTACAATTTCAACAATCCGCCGAGCACAACGTTGAACCTGGAGGAATACGAGAAGACCGGCGAGGCAAAAGTGACGCCGTTAAACTCGAGCGTGTCTGGGAGTAGTTCCTCGGACGATAAGAGCCCGAACAAGCAGGCGACGCCTCCACCATCGTCGATCACCGTGAACGCGTCCCAGACTAGCGAGATTAAGCAAGAGGTGCAGGAagttcaaccccagtgtcacgttcaatcgcagcagtcgcaacaactacaacagcagcaacaggaggaacagcaacatcactctcccggAAGTTCCGGCGGGCAGCAGTCCAGGCCGCATTCCCCGGCGCTGAGCATGAGCTCGGTTTTTTCCGGTATCCATCACGACGTCTCGTCTCACGCGACGACGACCAGCGCGCCTAGCGCGCCGATGCTCCCACCAAAGCTCACGCCGCAGAATTTTGCCAGTCCGAGTCCCAGCGCGAGCACCGTTGTTCCGGGCGCTATTGCCGCGATGGCGTTGACGCCGCAAAGATCTTTGAGCCCCGGCCGCGGCCCGACCGACTACTCGTTCGCCAGCAGCGGTAACGGCAGCAACTCGTCCGGCGGCAGTTCCGGAAAACGGGCGAACCGTACGCGATTCACCGACTACCAGATAAAGGTGCTGCAGGAATTCTTCGAGAACAACGCCTATCCGAAGGACGACGATCTGGAGTATCTGAGCAAACTGCTGGGGCTGAGTCCGCGCGTGATCGTAGTCTGGTTCCAGAACGCGAGACAGAAAGCGCGTAAGGTTTATGAGAATCAGCCAGCCGCCGAACCAGTGACCACGGGTAGCCGCGAGGGCGACGACGGTTCCGGCCGCTTCCAACGGACCCCAGGCTTGAATTACCAATGCAAGAAGTGTTTGCTGGTGTTTCAGAGATACTACGAGCTCATACGTCATCAGAAGACGCACTGCTTCAAGGAGGAGGACGCGAAGCGGAGCGCCCAGGCGCAGGCGGCCGCGGCCCAAGTCGCCGCGGTCCTCAGTTCCGAAGATagcaacagcagctcggccactaccaccaccgctgctaacacgatgtccagtaatcaagcgaacactcccgccctcgcggaacagctacaacaaccgttgaacgctaccacgtcaccgctccatcaacaacagcagacgatcggacagtcgcagcagcagcagcaacagcagtcacaacagcagcagtctcaacctcagcaacagcaacagcagaccgagtctaaggagggtagctttcaatgcgacaaatgcaacctgatgttcggccgattcgaactctggcgCGAACATCAGCTCGTACATATCATGAACCCATCCCTGTTCCCACCAGCCTATCCACCGGATTCACCGTTCGGAATACTACAACAACAAGCGCTGAACGCTACCACCGGAGTAGCCACGGACACTCCCCACCCGTTGATCGCGATGATGCAAGACAGGAAGAGGAAGTACGATGACGCCGACGAGGGATCCACCTGCGACACTCGCTCTAACTCCGAGCACAGCGAGCAGCCGAAGGACAAACGATTACGAACGACGATACTGCCGGAACAGTTAGATTATTTATATCAGAAATATCAAGCCGAATCGAATCCGTCGAGAAAGATGCTGGAGACCATCGCGCGCGAGGTCGGCTTGAAGAAACGAGTAGTACAGGTGTGGTTTCAGAACACCCGCGCCCGCGAACGCAAGGGCCAGTTCCGTGCGCATAGCCAAGTGATCAACAAGCGCTGTCCATTCTGTCCGGCTCTGTTCAAAGTGAAGTCTGCGCTGGAGTCACATCTGAGCAGCAAACACGCCGATCAGGTTGCCCGGGGTGAGGTCAATATCGATAACATCCCTGACGAGGAGCTGTCGATGGAGTCAGCTCCGTCGAACCAAGGCACGCCGAACATGATGCCGCCGCTGTTTCCACCGTTCAACACCGAAATGGAGGCCTCTTTAAAGAAGTACTACGAGGAGTCAATGAAACGATACATCAGCGAATTACAGGCGCATGCTAGCAATGGGAAGCAGGAGGCGGCGAACCACCAAACCGCCGGTGGTAACAGCGGCGAGTCCCCGTTGGATCTGAGCAAGCCGGTCGATCTCAGCCGTCCCATGAAGCTGAGCCTCGGCGGGTTGAGCAATCTTCTCGATGAGCAGCACGTTGTGCATTTCCGCGGCGGCAGCGACTGCGGCCCGCTGACTGACCTCTCCGAGCGCAGCATCTGCGACGACGACAGCATGAGCGAGACCACCGAGTTCCTCGACGACGAGAGCGGACCAGCGAGCCCAGCGTCCAGCACGCAGAGCTCCAGGCAGGGGCCTGCGTCGGCTGGCACCGGAAGCACCACCGCTCCGCCGGTCGCCGGCACCGGAACCAGCAGCACCGGCCAGTCCAGCGGCAAAAGATATCGCACCCAGATGTCGGCTACGCAAGTGAAGGTGATGAAGTCGCTGTTCTCGGATTATAAGACCCCCACTATGGCCGAGTGCGAGATGCTCGGGCGAGAGATCGGTCTGCCCAAGCGGGTCGTTCAGGTTTGGTTCCAGAACGCACGGGCGAAGGAGAAGAAAGCGAGACTGGCGGCGGGCCTGCCCGCCGAGGGCTCGGCCGTTCAACCCCACCGGGGACCGACCGGGCCCGACGAATGTAGACTGTGCTCGGTCCGCTACTCGGCCAAATCGCCGCTCCAAGAGCACGTATTCTCGCGACGACACATCGAATCGGTGCGTGTCGCCGTCGAGGAGGGTAGCCTCGTGCCGCCGACACCCGGTGCACCGATCGTTCCTGCCGGGAACTCGGGCGCAGCGGGGATCGTCGGCTCGCCGGTGGTCGGCCAGCAAGCGACCGGTAATCAACAGCAGCAACAGCAGCAGCAGCAACAACAATCGGACGAAAACATGATGTACGGATCCTTGTTCCTCCATCCAACGGCGATGTTCCAGCCGCAGCAACAGCAACACCCGGGCGCCGGGGCGACCAGCACGGCTACAACCACGGCCGGTGAGTGTCTGGCTGACCTCTTAGATTCGTAA
Protein Sequence: MLVLQQNVKHMQTLSALQSHHQQAQHHHQQAQQQHQQQQLEQLLHLGGLDKPQHAEAALADMAYNQALLIQMMTGGQLPPQLPPEIMGGMASMGAMGNLGGDVGLSPDSMDPPPEPADPDPSHLYHCCVCNNFATDSLEALGHHLAVDRTRTREGEILALVAGHFVCKLCSYKTNLKANFQLHCKTDKHLQRLQHVNHVKEGGLRNEWKLKYLASPTSAAQLRCHACDYYTNSAHKLALHAASPRHEAAALLLRHLLEASANVPSQAKLYHCALCGFSARHRLPLLQHVRSLRHLQMEQLHQLHRRSGIQGNETPHTDIGDVFQVMSDPDAPPAQQSSPTTPTTPNATSANNERREEGSDCGSEVKQEPDNDQEPEQEPENDQDDVSCPYCTYQPTSRDELRQHLQVAHVQDAEDKAEACVKEEPPPELLCPLCQDGFKERSALEKHVMQIHSVNSDGLQRLLLLVDQSHWLNNNPRSTSTPAVTTPTSPTTTTKQPAEEDLSERGANDEIEEITRETHPATTPTLAVSEKHVYKYRCGQCSLAFKTLEKLQQHSQYHAIRDATKCALCGRSFRSVQALQRHLESAHADLHEDELAQYKQSLLHANPLFQALTEEALRRQGNLTGEQNVEDDASKADEEESDASDSSPLHKEQRLLEDYLNSQPVAEDSYHDPGRKFKCHRCKVAFTRQSYLTGHNKTLLHRKGEKMSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQGNNNTLISVVPPASPTESPDSQQDQDKKPYKCNICKVAYSQGSTLDIHMRSVLHQTRASKLPDLAASGQLDLARPLIEQPPPSSPNSPPVNTSTSGNSGTMLSCSRCSALFVNQEQLATHQQLYCIFSNPLALFQQLAASQQLASSTPSSAKTPPPTSTTPGPQPHMQQSTQHSTQTTQDILSQPRHKTSQMYTHLLESFGFDLVMQFNENHQRRQRKEEEAAAALQAQQEQQKQEQQKQALAAQAAREREEEAEEHTDDDVIPELTRSTCQHCNKEFSSVWVLKAHCEEVHRDLVPREFLEKYAQQFKCEYEKKSVVVTAATSSSTSSGPRSSTPASGQPQDLTSDKEQRDKEKEETVENKDRVSKTPEATSTTPATTPALSNTPVSSTDSATPTVLPTNSSQHLQQQQQQQQQQQQQHAQLTLAQQMTEIQAAFNAMAASQLQQQLQQYPGLMMGMMGLPLGLNVPALAAMNLQPPLVPMMLPPPPYDGTATGYPPINAQADLLAKQHLALQQQQAAAANAAASQKRARTRITDEQLKILRAHFDINNSPGEEQILDMAAQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVTPLNSSVSGSSSSDDKSPNKQATPPPSSITVNASQTSEIKQEVQEVQPQCHVQSQQSQQLQQQQQEEQQHHSPGSSGGQQSRPHSPALSMSSVFSGIHHDVSSHATTTSAPSAPMLPPKLTPQNFASPSPSASTVVPGAIAAMALTPQRSLSPGRGPTDYSFASSGNGSNSSGGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLGLSPRVIVVWFQNARQKARKVYENQPAAEPVTTGSREGDDGSGRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQVAAVLSSEDSNSSSATTTTAANTMSSNQANTPALAEQLQQPLNATTSPLHQQQQTIGQSQQQQQQQSQQQQSQPQQQQQQTESKEGSFQCDKCNLMFGRFELWREHQLVHIMNPSLFPPAYPPDSPFGILQQQALNATTGVATDTPHPLIAMMQDRKRKYDDADEGSTCDTRSNSEHSEQPKDKRLRTTILPEQLDYLYQKYQAESNPSRKMLETIAREVGLKKRVVQVWFQNTRARERKGQFRAHSQVINKRCPFCPALFKVKSALESHLSSKHADQVARGEVNIDNIPDEELSMESAPSNQGTPNMMPPLFPPFNTEMEASLKKYYEESMKRYISELQAHASNGKQEAANHQTAGGNSGESPLDLSKPVDLSRPMKLSLGGLSNLLDEQHVVHFRGGSDCGPLTDLSERSICDDDSMSETTEFLDDESGPASPASSTQSSRQGPASAGTGSTTAPPVAGTGTSSTGQSSGKRYRTQMSATQVKVMKSLFSDYKTPTMAECEMLGREIGLPKRVVQVWFQNARAKEKKARLAAGLPAEGSAVQPHRGPTGPDECRLCSVRYSAKSPLQEHVFSRRHIESVRVAVEEGSLVPPTPGAPIVPAGNSGAAGIVGSPVVGQQATGNQQQQQQQQQQQSDENMMYGSLFLHPTAMFQPQQQQHPGAGATSTATTTAGECLADLLDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00302859;
90% Identity: iTF_00302859;
80% Identity: iTF_00302859;