Basic Information

Insect: Ceratina calcarata
Gene Symbol: topi
Assembly: GCA_026724355.1
Location: JAKKRE010000005.1:1409386-1412031[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.3 37 5.6 2.1 1 23 247 269 247 269 0.93

2 15 0.11 14 7.0 1.0 2 23 276 298 275 298 0.95

3 15 0.0012 0.14 13.2 0.4 2 21 305 324 304 325 0.92

4 15 0.00047 0.057 14.5 2.4 1 23 332 354 332 354 0.97

5 15 4.5e-07 5.4e-05 24.0 1.0 1 23 360 382 360 382 0.95

6 15 0.11 14 7.0 6.6 1 23 431 453 431 453 0.98

7 15 0.2 24 6.2 0.3 1 23 459 481 459 481 0.93

8 15 0.044 5.4 8.2 1.6 1 23 491 514 491 514 0.96

9 15 0.058 7.1 7.9 0.0 1 20 528 547 528 549 0.92

10 15 0.0046 0.56 11.3 0.1 1 23 554 576 554 576 0.98

11 15 2.1e-06 0.00025 21.9 3.1 1 23 582 604 582 604 0.98

12 15 0.00013 0.016 16.2 0.4 1 23 610 633 610 633 0.97

13 15 0.05 6.1 8.1 0.7 1 23 639 661 639 661 0.89

14 15 3.3e-07 4e-05 24.4 2.2 1 23 667 689 667 689 0.99

15 15 6.3e-06 0.00077 20.3 4.9 1 23 695 718 695 718 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.3	37	5.6	2.1	1	23	247	269	247	269	0.93
2	15	0.11	14	7.0	1.0	2	23	276	298	275	298	0.95
3	15	0.0012	0.14	13.2	0.4	2	21	305	324	304	325	0.92
4	15	0.00047	0.057	14.5	2.4	1	23	332	354	332	354	0.97
5	15	4.5e-07	5.4e-05	24.0	1.0	1	23	360	382	360	382	0.95
6	15	0.11	14	7.0	6.6	1	23	431	453	431	453	0.98
7	15	0.2	24	6.2	0.3	1	23	459	481	459	481	0.93
8	15	0.044	5.4	8.2	1.6	1	23	491	514	491	514	0.96
9	15	0.058	7.1	7.9	0.0	1	20	528	547	528	549	0.92
10	15	0.0046	0.56	11.3	0.1	1	23	554	576	554	576	0.98
11	15	2.1e-06	0.00025	21.9	3.1	1	23	582	604	582	604	0.98
12	15	0.00013	0.016	16.2	0.4	1	23	610	633	610	633	0.97
13	15	0.05	6.1	8.1	0.7	1	23	639	661	639	661	0.89
14	15	3.3e-07	4e-05	24.4	2.2	1	23	667	689	667	689	0.99
15	15	6.3e-06	0.00077	20.3	4.9	1	23	695	718	695	718	0.96

Sequence Information

Coding Sequence: ATGAACGTGTGCAAAACCGAGTCGATTAGCACTTTGAGCGAGCAGGAGGACGACCTCGATTTCGAGGGGTCAATCATTTGGTCCCAAGAGGAACCGCTTTCCTCGAACGAGATTTTAGAATTTCAACCGGAACCTGAGAATGAGAATCGGCTCAAGTCTCTCTGCCGTTTATGCGCCGGAGAAACCCCAAATCCGATTTATATTTATTCCGAGTTCGGAGAATCCCTCAGACTTTTGCATAAAATAAACACCTGTCTCAGTATTAAGGTAAAAAAAACTGATCCTCTTCCGAAGCAACTCTGTCCGACTTGCGTCGAAAAGATCACCTGGTGCAACGACTTCGACGTGCAATGCATCAGAGCCGAGGAGACCCTCTTCGAGATTTTAAAGCAAAGACATTCGTTCAACAACTCCAAAAGCGATGGGAACACCGAAGAGAATTCAGATTGCTGTCCGTTATGCGTGGAAGGACGGATGAGAGTATATGAAGAAGATAAGGAATCAAGGAAAGACATTGAACTGTACGATAGCGACATCGTCCTCGAGAGCAGCGACGAAGAACAGATTCCTAACGAGATTAAAATAGAAGAAGAACCAGAAAACGAATCTATAACGCTGGTCTGTCTAGGTACCAAACAGAAGTACTTGAAATGTGGGGCTTGCATGAATCTGTATCATACGAAAGAGACTCTGGACGAGCATAAATGCAAGCCTAACTTGCAGTCTACTTCAAAACCGTACAAGTGCGAGGTTTGCTTCGCGACATTCACTTTTGAGGAGAGACTGCAGTTCCATCAAAATTTTCACAAAGATGCGAAAGCGTTGTACTGCGACATTTGCAAGATCACTTTCGGCAAGGAATTGAAATTGTATTATCACTACAAAAGGTATCACTGCAAGGATGGAAGAGTCTCCTGTTTGCAGTGTGGAAAGTTATTTGAAAATCAGGATGGGTTGAAGAAACACGTTTGTGTAGATGGGAAGACGaggcctcacgtctgcgaggtctgctctaagggattctgcgacggatacactttgaaacgacacgtggtcactcacctcccagagaagccttataaatgtccggagtgttcaaagagtttcacacagaagtcgagattgaacaaacacgtggcgggtcataGTATCATCTTCGAGAATAGTCAAACCATTTGGAGATGCGTTTGCTGCGGCGAAGCGTTTGGTAGCTGTGAATCCGCGGACGAGCATTGCAAGAAGCACGAGGAGAAGATCAGTTTGATCGAAGAATTACAAGTACTAAAATTGTACCACTGTGAATTCTGCAGCAGTCATTTCGCAGACATGGAGCACTTGAAGAGCCACAGAGAGACTCACGTTATTGAAACACCGTACTCTTGCACCCAGTGTAATTCCATATTCAAATCGTTCGCTGAGGCTGTCCTTCACTGGAAGGAACACCCGAGGATATTCAAAGTATTGGTGGTGTTCTTCTGCGAGATCTGCGACAAAGATATGAAAGAGCTGTCCTTGTTATACAAACATAAGCAGAAGAGGCACCAGCCTGTGGCTAGGAAGTCTGAGAAAGGGAAGGAGAAGTTCATCTGCGAACTTTGCGGTAGCGTGTTTGCTAGCATTGAAGATTTTCAAGAGCATGGCAAGTACAGGTGCTCTAAGTTCCCTTGCGATATCTGTGGGAGTCTTTTACCAACCGCCAATTCATTGAATGCACACAAGAGGAGGCACAGTGGCCTAAGACCgtatgtttgcaatatctgtgggaagagttatacacagtctagccacatgtggacgcacaaacggttccacatgggcgtgaaaccatacgcctgtgaatactgcgaccagagattcacaataaagcccgacctggctgatcacaccaggaagaagcatacaagggaaagaccgttcaaatgcgacgtttgcaacaaggctttcttaaccggctcagtgttctaccaacacagattgatacacagaggcgaccggagatacaagtgccactactgtgaaaaggcattcacccggacagaggctttgaacaatcatataaaaattcatactggtgagaagcctcacgcttgcgacgtttgtggcagatgtttcaggcaaaaaggagacatgaggaaacacagacggactcaacataCTGCCAAACAAGATACAAAGTAG
Protein Sequence: MNVCKTESISTLSEQEDDLDFEGSIIWSQEEPLSSNEILEFQPEPENENRLKSLCRLCAGETPNPIYIYSEFGESLRLLHKINTCLSIKVKKTDPLPKQLCPTCVEKITWCNDFDVQCIRAEETLFEILKQRHSFNNSKSDGNTEENSDCCPLCVEGRMRVYEEDKESRKDIELYDSDIVLESSDEEQIPNEIKIEEEPENESITLVCLGTKQKYLKCGACMNLYHTKETLDEHKCKPNLQSTSKPYKCEVCFATFTFEERLQFHQNFHKDAKALYCDICKITFGKELKLYYHYKRYHCKDGRVSCLQCGKLFENQDGLKKHVCVDGKTRPHVCEVCSKGFCDGYTLKRHVVTHLPEKPYKCPECSKSFTQKSRLNKHVAGHSIIFENSQTIWRCVCCGEAFGSCESADEHCKKHEEKISLIEELQVLKLYHCEFCSSHFADMEHLKSHRETHVIETPYSCTQCNSIFKSFAEAVLHWKEHPRIFKVLVVFFCEICDKDMKELSLLYKHKQKRHQPVARKSEKGKEKFICELCGSVFASIEDFQEHGKYRCSKFPCDICGSLLPTANSLNAHKRRHSGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACEYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTQHTAKQDTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00085636;
90% Identity: iTF_01417868;
80% Identity: -