Crun003686.1
Basic Information
- Insect
- Cephus runcator
- Gene Symbol
- ZFX
- Assembly
- GCA_030142495.1
- Location
- JARQTC010000366.1:2229806-2232639[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.069 5 7.9 3.6 1 20 365 384 365 385 0.94 2 10 1.4e-05 0.00099 19.5 2.4 1 23 544 566 544 566 0.97 3 10 0.0041 0.3 11.7 2.0 1 23 572 594 572 594 0.93 4 10 1.9e-06 0.00014 22.2 0.5 1 23 599 621 599 621 0.99 5 10 2.3e-05 0.0017 18.8 0.4 1 23 627 649 627 649 0.98 6 10 7.6e-07 5.5e-05 23.5 1.4 1 23 655 677 655 677 0.98 7 10 0.0002 0.015 15.9 0.3 1 23 684 706 684 706 0.92 8 10 2.4e-05 0.0017 18.8 3.4 2 23 713 735 713 735 0.98 9 10 1.5e-05 0.0011 19.4 0.7 1 23 741 763 741 763 0.98 10 10 6.6e-06 0.00048 20.5 1.7 1 23 769 792 769 792 0.94
Sequence Information
- Coding Sequence
- ATGAATAAGAGTGTGGATTCTATTTACAAGTGTCGCCTTTGCCTTACGGACATCAACGAGACTAACTCAGCGCCCATATTTTCACAATTAGAAACATGTATAAACGGTATTCCTCTCTCGGCCAAAATAATGGTCTGTGTATCACTTACGGTTCAAGAAGACGACTCCTTTCCACAACAAATATGTAAAAACTGCGAAGATcgtataaattgtttttatacatttcGTGAAACATGCTACAGAGCATACCTTTCACTCATTCAAGAATGCGCTAATTGCAAACGTCTTGAACAAGAGATTCAcaaacaaaatatgaaaaataatcggaTAAAAGATTACAAGGGACGTACATCAAGAGAACATcgtaagaataaaaaacacATGGCTGAATTAAAATTGAGTAAGAACGTACAGGAGcctagaaatatattaattgatgCTATAGATTTTATCATTGGAGACGGAACGTACGTGGAAACGACAGATGAACGTGAAAACTTACGTGCtgataaattgtcaaaaaatgcAGTCCATCAGGAGTCATCTAAATCAGAAAATAGCGCTATGAAAATAGTGGCAATCTGTCATGATGACACAGTGAAGAGTACAAAAGATGGTAACGAGATAAATATGGAAGGTAAAAATGGTCgagtaaatagaaaaagcaGACAAGCATCACATAGTCTAGGTACAACAGAGGAATCCGAATATGATTTGGAACAAAATATACCACAACATCATATCGTTTGTGTTGATACGAATCAGCCATATGCTAGTGGAGTACTAAAACAAGATACTGTAGATATTGAAAACAGTTCAAAACtaaccaatgaaaaatatacaaaagcaaagacattgaataaaattgaaaaaatcatacaagCGGCGCAACTGCAGGAAATAATTCCTTTAGACCCTACAGTGGAGAAACAAAGTGAAGattgtgaaaatttaaacaatgTGGAAAATTCGACCGTGGAGGAAACTGCTCCAAATACATATTTGGATGATTCGACAATGGAAAGTTGCTACCAAGTGGAAGAAATAGAAGAGCAAATACTTTGCGGTGAATATATGGAGCGTAGATATAAGTACAAATGTTTACGTTGCCATAAATGCTTTGCCGACCTTCATATGGTGACAATGCATTATATTGACTGTTGTCGCGATACGGAAATATTAAGGAACGATCAAACTCTTGATCAACCAATCGGAGTGGAGCATTTAGATAATAACTTTAAGGATACATTAGTAAACTGCAATGCCGACCATGCAACGGAAGAATCGCTGACAGATAAAGAAACTTCTGAAACACGACTTAAGTGTATTTGCAATGACGATACGTCAAGTAGCAAGTATAGGATATCCTTAGAGGAACCAAATAGTTTTAAAAAGGAATACGAATCAGATCTGGACACTGAAATAGAAGTAAATGGTTCAGATGATGTTGATGCCTTAAACATTAGGAATATGAGAAGCGATGTCTCTAGTATCAATACTGAGATACCAATAATTCGCACAAACAGCGATGGCGCGGAATCAAACGGCAACACTGTTAAATCAAAcgatgtaaatgaaaaatcgcaAAGTCAAAAACGAAAACGTAAAAGTCATAGGTATAAAATGGACCATCCGTGTCCCCACTGTAATAGCATGTTCAGAAATGCTTCTTTATTAAAGAGACACTTGTCAGTACACACCGGCGAGCGGCCTTACGcatgtgaaaaatgtaataggAGATTTTCTCAGTTGGGACAGTTAAACTTCCAtcgtaattttcatgaaaatcctCGTTATCGTTGTGAAATATGTAACAAGCCATTTTTGCGACCAAGCGATATTCAAAAGCACATGAGAACACACACTGGTGAAAAACCATACAATTGTAAATTGTGCTCAAAGTCTTTTGCACAATTGGTTGCTCTGCAACAGCATGAGCGAATTCATACAGGCGACAAGCCATATACTTGCGAAATATGCGGAAAGCGATTTACGCAAAAAGCCAATAAAACTAAACACGTGAAGATACATAAGGAGGGTGCAAAACCTCACACTTGCGAAATTTGCGGTAGAAGTTTTTCTGACTTGAACGAAATGGAATTGCATAGGGGTGGCCATGGGGGTGGAAAGCCAAGAAAGTGTGACCATTGTAATGAGAGTTTTCGGAAAATTTCTGAACTGACGCAACATATAAGGCGCTTTCACACTTTCGAGAGACCGCATAAATGTGCTATTTGTCCTAAAGCTTTCTATTCAGTTTACAATTTGAAGCAACACGTCATGGTCCATACTGGACAGCGACCTTTTATCTGTCCCAAGTGCGACTTGAGGTTCACGCAAAAAGGTAACCTTACCAAGCATTTTGAGAGAAAGCATGCGGAATACATgcttgaaaaggaaaaatacatAACGATTAGTGAGGAGGAATATCATGGCGATGATATGTTGATCATAGAAGGATCTATGAGTGACAAGATAAGTGAACCGTTGATTGTCGAACGGGAAGAAACAATTGAGTTAAGAAatgaagatttgaaaaatatcagtgGTAATAATATTCAGATTTTGGACATGGGGGAATAA
- Protein Sequence
- MNKSVDSIYKCRLCLTDINETNSAPIFSQLETCINGIPLSAKIMVCVSLTVQEDDSFPQQICKNCEDRINCFYTFRETCYRAYLSLIQECANCKRLEQEIHKQNMKNNRIKDYKGRTSREHRKNKKHMAELKLSKNVQEPRNILIDAIDFIIGDGTYVETTDERENLRADKLSKNAVHQESSKSENSAMKIVAICHDDTVKSTKDGNEINMEGKNGRVNRKSRQASHSLGTTEESEYDLEQNIPQHHIVCVDTNQPYASGVLKQDTVDIENSSKLTNEKYTKAKTLNKIEKIIQAAQLQEIIPLDPTVEKQSEDCENLNNVENSTVEETAPNTYLDDSTMESCYQVEEIEEQILCGEYMERRYKYKCLRCHKCFADLHMVTMHYIDCCRDTEILRNDQTLDQPIGVEHLDNNFKDTLVNCNADHATEESLTDKETSETRLKCICNDDTSSSKYRISLEEPNSFKKEYESDLDTEIEVNGSDDVDALNIRNMRSDVSSINTEIPIIRTNSDGAESNGNTVKSNDVNEKSQSQKRKRKSHRYKMDHPCPHCNSMFRNASLLKRHLSVHTGERPYACEKCNRRFSQLGQLNFHRNFHENPRYRCEICNKPFLRPSDIQKHMRTHTGEKPYNCKLCSKSFAQLVALQQHERIHTGDKPYTCEICGKRFTQKANKTKHVKIHKEGAKPHTCEICGRSFSDLNEMELHRGGHGGGKPRKCDHCNESFRKISELTQHIRRFHTFERPHKCAICPKAFYSVYNLKQHVMVHTGQRPFICPKCDLRFTQKGNLTKHFERKHAEYMLEKEKYITISEEEYHGDDMLIIEGSMSDKISEPLIVEREETIELRNEDLKNISGNNIQILDMGE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01474913;
- 90% Identity
- iTF_00292450;
- 80% Identity
- -