Basic Information

Gene Symbol
-
Assembly
GCA_036026175.1
Location
JAYRBY010000677.1:557132-560016[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.046 4.3 8.5 0.5 6 21 12 27 8 28 0.90
2 14 5.9 5.5e+02 1.9 0.2 2 20 34 52 33 57 0.88
3 14 0.63 60 4.9 0.3 1 12 248 259 248 268 0.89
4 14 0.14 14 6.9 0.7 1 20 376 395 376 397 0.94
5 14 0.0007 0.066 14.2 0.1 2 23 402 423 402 423 0.97
6 14 0.0028 0.27 12.3 2.3 2 23 435 456 434 456 0.94
7 14 0.16 15 6.8 0.2 1 23 475 496 475 496 0.83
8 14 0.00093 0.088 13.8 0.0 2 23 502 523 501 523 0.95
9 14 5.7e-05 0.0054 17.6 4.8 1 23 566 588 566 588 0.99
10 14 2.5e-06 0.00023 21.9 3.7 1 23 594 616 594 616 0.96
11 14 0.00028 0.027 15.4 4.1 1 23 622 644 622 644 0.97
12 14 1.7e-06 0.00016 22.4 0.8 1 23 650 672 650 672 0.98
13 14 0.00011 0.01 16.8 0.2 1 23 676 698 676 698 0.99
14 14 0.00047 0.044 14.8 0.2 1 23 706 728 706 728 0.97

Sequence Information

Coding Sequence
ATGGGATCGCTGAGTCTTCTTTGTCCCATGTGTTGTGGGGAGAGTTTCGACAACTCACAGAcattaaaaagtcatttgttAAGCATGACAAACAACTTATACTGTCCTCGTTGTTCTGAGAGATTGGACTCCGTAATGGCTCTTATTCAGCATTTAGATGGTTGTGGTCATGGTACAGAGGCTGCAATACATTTGGTTGCTGAAGTCGATCCTGAATTAGAACCAGAACTAGAGGTAGAACCTCAAATAGAAGCAGAGTCAGAAGTTGACGAGTCAAAGGAAGAGACAGAAGTTTTAATGGAAGCTAGTGTTGAGCAGATCGATCAAGGATTTTTAGCAGCAGTAAAcgatggaaaaataatgatagttGGTGGTTCTCGTACAATACAAGTAGATGAAAATGGCCAAATCGAAGTAGTAGAAAAAATGGATACAGAATCAGAGGAGCTTGAGGTACCAACGTCATCCATACAAAACATGGAGAAGCTCTCTCCGATTGATGAGCCTTCTGAAGAAAAGGATACTTCTCGAGATTCACTGGCTAATCTGACATCTGCAGCCAATGGAATTAAgtcagagagaaaagatatgATGTCCATTTTACCAGACAATTCAGATCTCCTCAATGAAGAGGATGACAGTTTGATGGGCATGGACCATGTAAACGATGTCCAAGAACTGAATGATACTGGGCTTCTTGAAGTCAAGCAGGAACTTTGTGAGATAGAATCCGAAGCACTCTATAGTTGCAGCAGTTGTGGAATGAGTTTCAACTCTGTCCTGGAACATATAAAGCAATACCACGATGGACAGGAAGTCGTTCTCGAAATGGCTGAACAGCAACTAGACAGTATCGCAGCTTCAGTGGAGCCAGCTGTTCTTGAAGAACCAACCGCAGTCATACCGCCTCGTCAACGGCAAACAATGAACACTCTACGCACCGAAGAATGCGTCGACAGTGAAGGAAGACTCTATACCAGAAAGGTTGTGCAGATAGAAAGATTTTGGGACCGTCCAATGAGCGGAAGTCGTTCCTCCAAAGCACCAATGATAGAGAAATTTTTCTCTAACGCTGAAGGTGTCAAGGTACGCGATAAAACGGTAGCAGCAGCACCAGTAAGGATGTACCGTTGTAACCAGTGCTTGGAGCAATTTCCAAAGCTTGGGGATTTTCGCGTCCATGCGTGCCTTCGTGGTACTAATCGGTGTGATCGGTGCGATCAGGCGTTTGCAACTGCACGCGCGTTGCAGTTGCATGCAAAAGTGCACGAAGTCGACAGTAATGGTGGTCAAAGGGTGTTCCTTTGCTCTGCATGTGGTACAGAGTTTTCTTCCCATAAGAGTCTACGACTTCACTCAAGGATGCATGCGCCAGTGAGGTCGCGACATGTAGATGCTCCTGAAGGTACTCACAGTGCTACGTTTACCTGCCTAGAATGTGGGAAAACATTGTCGGAATCTTACAGAGATGCTCACATGGCTCTACACACTGGCGATTCTGTTACTTGTAGTGTAtgcaatagaaaatttgaCTCCGCAGACAGCCTTGCTATGCATGCAGCTGTTCATTCGGATGCTAATCGTTCTCATTCGCCCACACCTCCCGCTAGAGATATTAATGCATCCCCTGTAGATGCAGCAGCGGAAGCGGCTGCTGCAGAAAGCGGTGGTGGTGatattgataaagaaaaaccatATCAGTGCCAACACTGTGGTAGAAGATTTACTAGACCTCATGAGAAAGTTAAGCACGAACGTATTCATACTGGAGAGAAACCACATGCCTGCGAAGTTTGCGGCAAAACTTTTCGAGTGTCTTATTGCTTAACATTACACATGAGAACACATACTGGTGTAAGGCCTTATGCGTGTCAACACTGTGGCAAACGATTCAAAGCTTCATCGGTTTACAATCATCACTTGCTCACTCATGGCGAAGAAAGAGCATATACTTGTCCGTACTGTCCCAAAACCTTCAAGACAAGAGTGCAGCTTGCAGGGCACAAGAATAGTCATACAAAACCTTTCCGATGCACAGAATGCTCTAGACCTTTTGCATCGTTATATGCAGCCCGTGCTCATATTCAGACTCACAAGAAGGACAATAACCTCAAATTTAGTTGTTACATCTGTGGTGCATCCTATGGTCGTGCCTTTGCATTGAAGGATCATCTGAAGCAACATGGTCAGGATGTTCTTACACCGCCAGAACCCGCTCGCGAGGAGGAAGTTCGTGAGGTTGATGATTATTTACTTGCGGAGGAAGAGGCTGAGGACGAACTTGTTATACCTTCGCCTCTCCCGGGTGCACAGTCATCTGATGTCGAAGAGTCAGATTGA
Protein Sequence
MGSLSLLCPMCCGESFDNSQTLKSHLLSMTNNLYCPRCSERLDSVMALIQHLDGCGHGTEAAIHLVAEVDPELEPELEVEPQIEAESEVDESKEETEVLMEASVEQIDQGFLAAVNDGKIMIVGGSRTIQVDENGQIEVVEKMDTESEELEVPTSSIQNMEKLSPIDEPSEEKDTSRDSLANLTSAANGIKSERKDMMSILPDNSDLLNEEDDSLMGMDHVNDVQELNDTGLLEVKQELCEIESEALYSCSSCGMSFNSVLEHIKQYHDGQEVVLEMAEQQLDSIAASVEPAVLEEPTAVIPPRQRQTMNTLRTEECVDSEGRLYTRKVVQIERFWDRPMSGSRSSKAPMIEKFFSNAEGVKVRDKTVAAAPVRMYRCNQCLEQFPKLGDFRVHACLRGTNRCDRCDQAFATARALQLHAKVHEVDSNGGQRVFLCSACGTEFSSHKSLRLHSRMHAPVRSRHVDAPEGTHSATFTCLECGKTLSESYRDAHMALHTGDSVTCSVCNRKFDSADSLAMHAAVHSDANRSHSPTPPARDINASPVDAAAEAAAAESGGGDIDKEKPYQCQHCGRRFTRPHEKVKHERIHTGEKPHACEVCGKTFRVSYCLTLHMRTHTGVRPYACQHCGKRFKASSVYNHHLLTHGEERAYTCPYCPKTFKTRVQLAGHKNSHTKPFRCTECSRPFASLYAARAHIQTHKKDNNLKFSCYICGASYGRAFALKDHLKQHGQDVLTPPEPAREEEVREVDDYLLAEEEAEDELVIPSPLPGAQSSDVEESD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01131027;
90% Identity
iTF_01131027;
80% Identity
-