Basic Information

Gene Symbol
-
Assembly
GCA_036026175.1
Location
JAYRBY010000466.1:121506-122723[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00039 0.037 15.0 0.5 1 23 118 140 118 140 0.93
2 10 1e-06 9.7e-05 23.1 1.2 1 23 146 168 146 168 0.99
3 10 2.4e-07 2.3e-05 25.1 0.4 1 23 174 196 174 196 0.98
4 10 0.00051 0.048 14.7 1.0 3 23 204 225 203 225 0.97
5 10 1.4e-05 0.0013 19.5 2.5 1 23 230 252 230 252 0.97
6 10 5.3e-06 0.0005 20.9 1.8 1 23 261 283 261 283 0.98
7 10 2.2e-06 0.00021 22.1 1.1 1 23 289 311 289 311 0.97
8 10 2.8e-05 0.0026 18.6 1.3 2 23 318 339 317 339 0.97
9 10 1.9e-06 0.00018 22.3 3.3 1 23 345 367 345 367 0.98
10 10 1.7e-06 0.00016 22.4 0.4 1 23 373 395 373 395 0.99

Sequence Information

Coding Sequence
ATGAAGGAAGAGCCAGTCGACGAGTCCATCGATGACGAGGAGGAATACCAGTTGGAAGAATCCACAGAGATAACCTCCTCTCGAAGGAGCGACGTGGTATTTCAGGAGGACCTGATAAGTTTCGTCGATAAGACCAACAACAAGTATTCTCGTTCTGTGAAGAGGGAGCGCGGATGCGCAGCTGCACCTGACGACTATAAGGAATCGAAAGGCTACAAGGCTCGGGACGTCGGCTTCGGAATAACCTACGAGAACATTGAGACGACCAAGCGCGAGGCGAGCTCCGCTTCTTCGGAGACGACGGACGGTGCGACGGCTGTTGCTGAATCAGCTGCGTCGGAGAACAGGCTCTATCAGTGCCAGATTTGTGCGAAGCGCTTTAGATCGAAAAACTTATTTGAAGGTCATCTTGTGGCTCACAGTGACGCGAGGCCCTACCAATGTGACGTTTGCAATAAATCGTTCAAAAGGACAAACACACTTGCAGTGCACAAGCGGATTCACACCCGGGAACGTAACTTCGTATGTGACGTGTGCGGCCGCGCATTTGTCCAGGCATCTCAGTTAGCGACGCATCATCGTCGTCATTTTGAGAAGTACACGAGATTCTGCGAGATTTGCAGCAAGGGCTTCTTCACGAACGCCGAGCTTCACGGACACATGAACGTCAAGCACGAGGCCAAAGAGCACGTTTGTCAGGTTTGCGCGAAATCCTTTCCCAATAATCACACCCTTGCCAGACACTTGAAGATGCACGATCCAAACTTCAAACCCGTCAAGCATCAGTGTGAATTTTGCGGAAAAACCTTCGCCTACAAGAACTCGCTAGTGGTTCACGTAAAGTCGCACACCGGTGAGAATAAGTTTGACTGTCACCTGTGCGGCAAATCTGTCTCCTCGAAGGGCTCTCTTCAGGATCATCTACGACTTCACGGCGGGGAAAAATCTCTAGTCTGCGACGTTTGCGGCAAGGCATTCCATAAGAGGACAACGCTCGTCGTTCACAAGAGGACTCATACCGGGGAGAAACCGTACAGCTGCGACACCTGCGGGAAGTCATTCACTCAGCACTCGACTCTCGTAATTCACAAGCGCTACCACACAGGACAAAGACCCTATCAGTGCTCCTATTGCGCCAAGTCCTTCGTCTCCAGGGCACTTCTCAATGCCCACACTAAGGTCCATGTCGTTAACGTCATGATCGTTCAGCCGGTCTAA
Protein Sequence
MKEEPVDESIDDEEEYQLEESTEITSSRRSDVVFQEDLISFVDKTNNKYSRSVKRERGCAAAPDDYKESKGYKARDVGFGITYENIETTKREASSASSETTDGATAVAESAASENRLYQCQICAKRFRSKNLFEGHLVAHSDARPYQCDVCNKSFKRTNTLAVHKRIHTRERNFVCDVCGRAFVQASQLATHHRRHFEKYTRFCEICSKGFFTNAELHGHMNVKHEAKEHVCQVCAKSFPNNHTLARHLKMHDPNFKPVKHQCEFCGKTFAYKNSLVVHVKSHTGENKFDCHLCGKSVSSKGSLQDHLRLHGGEKSLVCDVCGKAFHKRTTLVVHKRTHTGEKPYSCDTCGKSFTQHSTLVIHKRYHTGQRPYQCSYCAKSFVSRALLNAHTKVHVVNVMIVQPV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01475634;
90% Identity
iTF_01131000;
80% Identity
-