Cpar003724.1
Basic Information
- Insect
- Cephus parvus
- Gene Symbol
- ZFX
- Assembly
- GCA_030142435.1
- Location
- JARQTA010000406.1:2268577-2271416[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.21 17 6.4 2.6 1 20 365 384 365 385 0.94 2 10 1.4e-05 0.0012 19.5 2.4 1 23 545 567 545 567 0.97 3 10 0.0044 0.36 11.7 2.0 1 23 573 595 573 595 0.93 4 10 2e-06 0.00017 22.2 0.5 1 23 600 622 600 622 0.99 5 10 4.3e-05 0.0035 18.0 0.3 1 23 628 650 628 650 0.98 6 10 8.1e-07 6.6e-05 23.5 1.4 1 23 656 678 656 678 0.98 7 10 0.00021 0.017 15.9 0.3 1 23 685 707 685 707 0.92 8 10 2.5e-05 0.0021 18.8 3.4 2 23 714 736 714 736 0.98 9 10 1.5e-05 0.0013 19.4 0.7 1 23 742 764 742 764 0.98 10 10 7e-06 0.00057 20.5 1.7 1 23 770 793 770 793 0.94
Sequence Information
- Coding Sequence
- ATGAATAAGAGTGTGGATTCTATTTACAAGTGTCGCCTTTGCCTTACGGACATCAACGAGACTAACTCAGCGCCCATATTTTCACAATTAGAAACATGTATAAACGGTATTCCTCTCTCGGCCAAAATAATGGTCTGTGTATCACTTACGgTTCAAGAAGACGACTCCTTTCCACaacaaatatgtaaaaattgcgAAGATCGTATAAATTGCTTTTATACATTTCGCGAAACATGCTACAGAGCATACCTTTCACTCATTCAAGAATGTGCTAATTGCAAACGTCTCGAACAAGAGATTCACAAACAAAATATGAAGAACAATCGGATAAAAGATTACAAGGGACGTACATCAAGAGAACATCGTAAGAATAAAAAGCACATGGCTGAATTAAAATTGAGTAAGAACGTACAGGAGcctagaaatatattaattgatgCTATAGATTTTATCATTGGAGACGGAACGTACGTGGAAACGACAGATGAACGAGAAAACTTACGTGCtgataaattgtcaaaaaatgcAGTCCATCAGGAGTCATCTAATTCAGAAAATAGCGCTATAAAAATAGTGGCGATCAGTCATAATGACACAGTGAAGAGTATAAAAGATGATAACGAGATAAATGTGGAAGGTAAAAATGGTCgagtaaatagaaaaagcaGACAAGCATCACATAGTCAGGGTACAACAGGGGAATCTGAATATGATTTGGAACAAAATATACCACAACATCATATAGTTTGTGTTGATACGAATCAGCCATATGCTAGTGGAGTACTGAAACAAGATACTGTAGATATTGAAAACAGTTCAAAACTagccaatgaaaaatatacaaaagcaAAGACActggataaaattgaaaaaatcatacaagCGGCGCAACTGCAGGAAATAATTCCTGTAGACCCTACAGTGGAGAAACAAAGTGAAgattgtgaaaatttaaacaacGTGGAAAATTCGAGCGTGGAGGAAACTGCTCCAAATACATATTTGGATGATTCGACAATGGAAAGTTGCTACCAAGTGGAAGAAATAGAAGAGCAAATACTTTGCGGTGAATATATGGAGCGTAGATATAAGTACAAATGTTTACGTTGCTATAAATGCTTTGCCGATCTTCATATGGTGACAATGCATTATATTGACTGTTGTCGCGATACGGAAATATTAAGGAACGATCAAACTCTTGATCAACCAATTGGAGTGGAGCATTTAGATAATAACTTTAAGGATACATTAGTAAACTGCAATGTCGACCATGAAACGGAAGAATCGCTGAcggataaagaaatttctgaAACACGACTTAAGTGTATTTGCAATGACGATACGTCAAGTAGCAAGCATAGGATATCCTTAGAGGAATCAAATAGTTTTAAAAAGGAATACGAATCAGATTTGGACACTGAAGTAGAAGTAAATGGTTCAGATGATGTTGATGCCTTAAACATTAGGAATATGAAAAGCGATGTCTCTAGTATCGATACTGAGATACCAATAATTCGCGCAAACAGCGATGGCGCGGAATCAAACGGCAACATCACTGTTAAATTAAAcgatgtaaatgaaaaatcgcaaAGTCAAAAACGAAAACGTAAAAGTCATAGGTATAAAATGGACCATCCGTGTCCCCACTGTAACAGCATGTTCAGAAATGCTTCTTTATTAAAGAGACACTTGTCAGTACACACTGGCGAGCGGCCTTACGcatgtgaaaaatgtaataggAGATTTTCTCAGTTGGGACAGTTAAACTTCCAtcgtaattttcatgaaaatcctCGTTATCGTTGTGAAATATGTAACAAGCCATTTTTGCGACCAAGCGATATTCAAAAGCACATGAGAACACACACTGGGGAAAAACCATACAATTGTCAATTGTGCTCAAAATCATTTGCGCAATTGGTCGCTCTGCAGCAGCATGAGCGAATTCATACAGGTGACAAGCCATATACTTGTGAAATATGCGGAAAGCGATTTACGCAAAAAGCCAATAAAACTAAACACGTGAAGATACATAAGGAGGGTGCAAAACCTCACACTTGCGAAATTTGCGGTAGGAGTTTTTCTGACTTGAACGAAATGGAATTGCATAGGGGTGGCCATGGGGGTGGAAAGCCAAGAAAGTGTGACCATTGTAATGAGAGTTTTCGGAAAATTTCTGAACTGACGCAACATATAAGACGCTTTCACACTTTCGAGAGACCGCATAAATGTGCTATTTGTCCTAAAGCTTTTTATTCAGTTTACAATTTGAAGCAACACGTCATGGTCCATACTGGACAGCGACCTTTTATCTGCCCCAAGTGCGACTTGAGGTTCACGCAAAAAGGTAACCTTACCAAGCATTTTGAGAGAAAGCATGCGGAATACATgcttgaaaaggaaaaatacatAACGATTAGTGAGGAGGAGTATCATGGCGATGAAATGTTGATCATAGAAGGATCTATGAGTGATAAGATAAGTGAACCGTTGATTGTCGAACGGGAGGAAACAATTGAGTTAAGAAatgaagatttgaaaaatatcagtgGTAATAATATTCAGATTCTGGACATGGGGGAATAA
- Protein Sequence
- MNKSVDSIYKCRLCLTDINETNSAPIFSQLETCINGIPLSAKIMVCVSLTVQEDDSFPQQICKNCEDRINCFYTFRETCYRAYLSLIQECANCKRLEQEIHKQNMKNNRIKDYKGRTSREHRKNKKHMAELKLSKNVQEPRNILIDAIDFIIGDGTYVETTDERENLRADKLSKNAVHQESSNSENSAIKIVAISHNDTVKSIKDDNEINVEGKNGRVNRKSRQASHSQGTTGESEYDLEQNIPQHHIVCVDTNQPYASGVLKQDTVDIENSSKLANEKYTKAKTLDKIEKIIQAAQLQEIIPVDPTVEKQSEDCENLNNVENSSVEETAPNTYLDDSTMESCYQVEEIEEQILCGEYMERRYKYKCLRCYKCFADLHMVTMHYIDCCRDTEILRNDQTLDQPIGVEHLDNNFKDTLVNCNVDHETEESLTDKEISETRLKCICNDDTSSSKHRISLEESNSFKKEYESDLDTEVEVNGSDDVDALNIRNMKSDVSSIDTEIPIIRANSDGAESNGNITVKLNDVNEKSQSQKRKRKSHRYKMDHPCPHCNSMFRNASLLKRHLSVHTGERPYACEKCNRRFSQLGQLNFHRNFHENPRYRCEICNKPFLRPSDIQKHMRTHTGEKPYNCQLCSKSFAQLVALQQHERIHTGDKPYTCEICGKRFTQKANKTKHVKIHKEGAKPHTCEICGRSFSDLNEMELHRGGHGGGKPRKCDHCNESFRKISELTQHIRRFHTFERPHKCAICPKAFYSVYNLKQHVMVHTGQRPFICPKCDLRFTQKGNLTKHFERKHAEYMLEKEKYITISEEEYHGDEMLIIEGSMSDKISEPLIVEREETIELRNEDLKNISGNNIQILDMGE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01474913;
- 90% Identity
- iTF_00292450;
- 80% Identity
- -