Cnig002888.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cephus nigrinus
Gene Symbol
-
Assembly
GCA_030142395.1
Location
JARQSZ010000298.1:379440-383379[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 2.8e-05 0.0023 18.5 0.7 1 23 146 168 146 168 0.95
2 15 0.001 0.086 13.6 1.1 3 23 176 196 175 196 0.99
3 15 8.2e-05 0.0067 17.1 0.1 1 23 319 341 319 341 0.98
4 15 0.69 56 4.7 0.2 1 23 347 370 347 370 0.96
5 15 8.9e-05 0.0073 16.9 1.8 1 23 396 418 396 418 0.98
6 15 1.9 1.6e+02 3.3 0.0 1 23 433 455 433 455 0.86
7 15 0.64 52 4.8 0.5 2 23 462 484 462 484 0.94
8 15 0.0032 0.26 12.1 2.8 2 19 492 509 492 513 0.95
9 15 0.00022 0.018 15.7 3.5 3 23 521 541 519 541 0.97
10 15 0.016 1.3 9.9 0.1 3 23 548 568 547 568 0.97
11 15 9.1e-06 0.00074 20.1 0.4 1 23 577 599 577 599 0.98
12 15 0.0039 0.32 11.8 0.2 3 23 607 627 605 627 0.97
13 15 0.0035 0.29 11.9 0.2 3 23 635 655 633 656 0.94
14 15 0.13 11 7.0 0.0 1 23 670 692 670 692 0.93
15 15 0.0019 0.16 12.7 0.0 1 20 1074 1093 1074 1096 0.94

Sequence Information

Coding Sequence
atggatgttGGCGGAGATTTAGCATTGCAGTGGGTGGAGGAAGTAGGAAACGTTATACATGAAGAAGTAATATGTGGCTTGGAAGCAGAACTCACTGCTCCGGAGGAAGAGGTTATTGGAGCATGCGAAGAGGTGTGTGTAGAGGAAACAGTGGAATCTGGTCCTGACTGTGGTACTACAGCAGATTCAGAAATCTTGATGGTACCTCAGACAAGTGACATGGAGTCTATCTATATAGTACCACAAGATCAAGGTCACGATTATCTTAATATAGAAGTAACTGAAGAGGTAATAGCCGATAATTGGGATAGATCCGGCCCAGACGATGGAGTGGAAATACCAGAAACAAAGGTGTCTCACGACAACCTTCTGGAATACGACGACATGGAAATCCCGTTACCAATCGATCAGGATTCGTATACAAATACCCGACCATATCCTTGCGATTTTTGCAGTCGTAGATTTCGGAAAAAAGCGAATCTAATGAATCACATGGTTGCACATCAAACAGACCGTCCGCATGGATGTAATCTATGCGGTGCACGTTACGTTAGAAAGTGTGATCTCATGAATCACTTAAAGATTCATGCGTACGCACCTTCTCGCGACGGTCTCGAGGATGATCTGAACGACGACGACTCCCTCGCCCATGACGAAGAGGAGCCGAATAGAGGTAGACGTAAGAAGGCTCAATCTAGTGCTCCAAGGAAACGCAAAAATAATGCTGCGGCAGCCAAAAGAAACAACGAggatatcaaaattgaaatgaacAAGTATATGAATAAGTCGTACGATTACGTTGACGAGGATATGCGACTTCTGGAAGAAATGACGAGTCGAAACACAGCAAGAAGTAGTAACTATGCATCCAGTTCGAGATGGACCGATGAGATATCCACAATGCCAAGCGAACCGCAACCACCCCGCTGGCCAATAACGGATCCAACAAAGCCCTACGTGTGTCAGCATTGCGGTGTCGGATTTGCTCGTGAAAAGGCATTGGCATCTCATGCTCGAATACATGGTGGTGATAGCCCCTTCGAGTGTACTTCATGTGGTGACATGTTTTGGGACGTGAATACATTGCGAGATCACGTTAGGATGAAGCATGGTGGTACCGTTCATACCGAGATGGATGAATATGATAACGATGCTACATATACTGGTGACGAAAGGTTTGGCGAGTTCTATTGTGAAACCTGTGGAGTACCTTTCCATCGTTTAGATCTGCTCAAACGTCATCGGAAAATTCACGTGAAGCAGGAGATCGACATGACTGAAGGATCGAGTCAGCATCACGTTTGCAATGTGTGTGGAGAATGGTTCGAAGAGGCCTTAGCATTACTTGCACACGCTGAACTGCACGCTAGATCTCCTAGTCGCCGCTGTCTATTGTGCGGTCAGAGGTGTCGAGACGATGCAGAAGTAGCAGAGCATGTGCGCCAATATCACGCGGATGATGCACCGCCAAATACGTGCAATCTTTGTGGTAAAACTTGCAAAGACAAACGaagtttattaaaacattCATGGATTCACAATGCCGATAAGACTTTCGGCTGTACAAAATGTGGCAAACGTTTCCACAGTAAAGCCAGGCTACGAAGACATATGGTATCTCATCGCAATAAAATGGTAGCCTGCGACGAATGTGGCGAGGAGTTTCCAGATGGTAGAGCTCTTGTAAGTCATCGTCATTCGCACAACAAGGATTTAGGCGGTAGATCATTTCCATGCCGGGAATGTGGCAAGACCTTCGGTAGCCGAAGCTCACAACAAATTCATATTCGTATTCACACCGGCGAGCGGCCTTATGGTTGCCGCTTTTGCTGGAAGGCTTTTGCAGACGGTGGAACTTTGCGAAAGCATGAACGTATACATACCGGTGAAAAGCCTTATGGTTGTGCGATTTGTCCTCGTGCTTTTAATCAACGTGTTGTATTACGTGAACACGTAAGGGCTCATCATTCTGGGCCCGATCCAAAGTGCCACGGAAGCATGACTCCGTACTTGTGTAAAGTGTGTGGCGACGCGTACTCGACATCCGAGGAGATAGTGGCGCACATAGTACAACATTGCGACGATAATACCGCGCTCAGAAGACAACCTCAATCCGGTCCTAGGAAATACAAGAGGAGGCGTAAGTTGAAACCTCTCGAAGGGGCAAGCATGAATATGCCTCGTATGAGTGAGAATTATGTAGATATGCTACAGCAACCTGGTTCAGATTCTGATGACAATACCAAACGAAAGCTTGGGAGAAAGAACAAGCAGCAGCATCGTGCTAATGTGGAGGAGGGTTATCAGAATGTCTTGAAGAGCTTCGAAAGCTCTTTAcagaatattaattcaattgtGAGCAATTCAAAGCTGAATCCTTCAAAGTCGAAGCTCtcgaagagaaagataaagaaggaagACAAGAAGAACGAAACTCAAACCTCCTCGCAATCTGGTAGGCCAAAAATGATACATACTCAAAAGACTAGGGTACCTGTCGAGGTAGGTAGCGATGGGGCCAAAAAAGGACAGAAGACAAAGACAATGGTTACAAGGACCCCAAAAGTGATGCCGAGTGAGCACAAGATGGGAATCTTCCCAGGTGGCGAAAGAAATCGACCTAGGACGAAAAATGTGAGTTATCATATCGAAGGGAAATTACATGTGACGCCTGCAACATTCCCAAAACCAAAGGAGGACATGGATAAACCTTTGTCGCCGCTCTTGACTAATATCAAAATCGAACCAGGACTTCAAAAAAGTTCTAGCAATAATCACAGCAACAATAACGGCAACATCCTCGGTATGAATATCGAAAAAGCTCCAACGCCTTTGAGAAAGAAACCCGTCGTCATGAGGAGAGTGAGAAAACAGAAGCAAGTGGTGATTAAACAAGAGCCAAGAGATATAGAtgacgaagaggaggatgagatgcaaaacaataatatttcacagaGAGTCGAGCCAGTCAGACTCTCCGCAAATCGTCTAGATCGAACCAATATGGATCTTAATTTCGAGGCTAATCTTCTAAATGCCGAGCATGAGTCCATTCTTCCAGATATTGGAAGGTCCGATCACATGGACGAtatggaaaatggaaatgtcAAACTGAGCGTCAAGATGGTCGAATCGACACCACAGAGATTGATGACCATACATAGTGTTATTGGACCAGTAGACGATGTGCCAGAGACCATAATACCTGATGCTGTTGAATATACTTGCGAGATGTGTTCGGCAGTATTTTCAACCCGTGCAGAGCTTTTGGTTCATGTGCCGATACACATTTGA
Protein Sequence
MDVGGDLALQWVEEVGNVIHEEVICGLEAELTAPEEEVIGACEEVCVEETVESGPDCGTTADSEILMVPQTSDMESIYIVPQDQGHDYLNIEVTEEVIADNWDRSGPDDGVEIPETKVSHDNLLEYDDMEIPLPIDQDSYTNTRPYPCDFCSRRFRKKANLMNHMVAHQTDRPHGCNLCGARYVRKCDLMNHLKIHAYAPSRDGLEDDLNDDDSLAHDEEEPNRGRRKKAQSSAPRKRKNNAAAAKRNNEDIKIEMNKYMNKSYDYVDEDMRLLEEMTSRNTARSSNYASSSRWTDEISTMPSEPQPPRWPITDPTKPYVCQHCGVGFAREKALASHARIHGGDSPFECTSCGDMFWDVNTLRDHVRMKHGGTVHTEMDEYDNDATYTGDERFGEFYCETCGVPFHRLDLLKRHRKIHVKQEIDMTEGSSQHHVCNVCGEWFEEALALLAHAELHARSPSRRCLLCGQRCRDDAEVAEHVRQYHADDAPPNTCNLCGKTCKDKRSLLKHSWIHNADKTFGCTKCGKRFHSKARLRRHMVSHRNKMVACDECGEEFPDGRALVSHRHSHNKDLGGRSFPCRECGKTFGSRSSQQIHIRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYGCAICPRAFNQRVVLREHVRAHHSGPDPKCHGSMTPYLCKVCGDAYSTSEEIVAHIVQHCDDNTALRRQPQSGPRKYKRRRKLKPLEGASMNMPRMSENYVDMLQQPGSDSDDNTKRKLGRKNKQQHRANVEEGYQNVLKSFESSLQNINSIVSNSKLNPSKSKLSKRKIKKEDKKNETQTSSQSGRPKMIHTQKTRVPVEVGSDGAKKGQKTKTMVTRTPKVMPSEHKMGIFPGGERNRPRTKNVSYHIEGKLHVTPATFPKPKEDMDKPLSPLLTNIKIEPGLQKSSSNNHSNNNGNILGMNIEKAPTPLRKKPVVMRRVRKQKQVVIKQEPRDIDDEEEDEMQNNNISQRVEPVRLSANRLDRTNMDLNFEANLLNAEHESILPDIGRSDHMDDMENGNVKLSVKMVESTPQRLMTIHSVIGPVDDVPETIIPDAVEYTCEMCSAVFSTRAELLVHVPIHI