Ccin007296.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cephus cinctus
Gene Symbol
-
Assembly
GCA_000341935.1
Location
NW:100493-108597[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 1.7 1e+02 3.0 0.3 2 19 605 622 604 623 0.81
2 10 0.46 28 4.8 1.8 1 23 632 655 632 655 0.97
3 10 3.1e-05 0.0018 17.9 0.6 1 23 661 683 661 683 0.98
4 10 0.11 6.9 6.7 2.3 1 23 689 711 689 711 0.97
5 10 3.6e-05 0.0021 17.7 0.3 2 23 718 739 717 739 0.97
6 10 1.1 68 3.5 3.1 1 19 745 763 745 768 0.90
7 10 8e-06 0.00048 19.7 2.3 1 23 772 794 772 794 0.98
8 10 0.004 0.24 11.2 1.6 1 23 799 821 799 821 0.98
9 10 2.2e-08 1.3e-06 27.8 0.5 1 23 827 849 827 849 0.98
10 10 0.00053 0.032 14.0 1.4 1 21 854 874 854 875 0.94

Sequence Information

Coding Sequence
atggaggtggaggaggaagaggcACGGATTTGCAGACTTTGCGGACAGTGTGGCAGCATTTATATTGATGTCTTTGGAGAGGAAGGAACGAAGAGATTATTGGGACTGAAAATACATACGAAAATCAACATTCTGATAGATGAGAGGGATGCTCTGCCCAAGGTGATCTGTGTTCAGTGTCTGGGAAAACTCGAATTCGTTTGCGACTTCCAAGAGGAGTGTCTTCGCACCCAGCAACTGTTACGCGATCGGTACAATCTGCCAACCTTAACAGATGTTatacAAGAAGATGATGGCCTCTCCCACGTTGTGTGCGTGCGATGCATGGGGACGTTGGAATTTTTATGTGACTTTCATGAAAAGTGTCATCTTACACAACGAGAACTATTATCAGCTaAAGAACGCCAAAACTTAGAAACCAATTTTAATGAAGACTGTGATGTTGATTCTGACAAGGAAAACATTTTGCCAGCTAAAGTTCCTCAGAAACGAAAAGTCATAAGGATTGTTCAGTCTGAGAAATCGAAAGTTCAAAAACTTAACAGCACAACCAATGAATCGCTCGTAAATTTTACTGAGAACGAAAATTCTAATTGCGATGAGAAATTTGAACAGAATAGGAACAGATTGTCTGAAAGTGATTCAGTGCATTCTCATGAAGATCTATCATCGGATTCGGAAGAGACTGAAATGTGtcaatcaatttcaaaatccacTGTAcctaagaaaaatttacctgAAGAAAATGCAGATTCAAATTCTGTGCCAAGCTACACGAAATTGGACGTTGTGGAAAATTTGGGAACTTTAAAAAAGACTGAGGAAACTGTTAAGGAAATAATAGACGATCAAAATAATGTTAGACATAATTCACAAAATGTTGGAAAATTCGTCGATGAGATTATTTGTACAGATACTCAGACTGAAATAGCGTCTAATAAGAATAATGAtcaagaaatttcaatagttaACCAAAAGAAATTTACCTGtatggaaaacaaaaaattgcatgatTCCAAAGacaacaatgaaaattctttagagACGAGAGAACGTGAGTTACAAAGTAATCAGGAGCCTATGAACTCTAATAATAATCCAGTGAATCACACAGAGAATGAGTCTGAGTCCGGAACGATCTTAACGGATTCCACAAAAAGTAAAGCTGTGCCTGTTATAGTTaagcaagaaaaatatgaatatgtaCGGTTACCAAATGAAGCAGCTTCGTGTTCAGcagaaaaaccaaagataaaTGGGACTAATAAACCCACAAATACAAGTCCTCCACCAGGTGACGAAGCTGAGGATGACATCGGTCATCACATTGCTACGTCATCCATAGCTTCCTCTAACTCTTCCCCATCTGTCAGAGAATCGTCCATAGACAATACAGAAGAAAATCATGATTCcactgaaaatttgaatacgtTCAAAGAACACAGCATGCAGAAGGACCACATGACGCAATTGAGGAAATCTGTCATAGAGATgttaaaaaatactaaatcTCAGAGCTCTTCCATCGAAGCCTCGGATGATCCTAATGACATAAAAATGCGACGTCGGACATCAAATAGTCTGAATTATCCATCGAGCTCCGATGATGCCTCTTTGATTGATATTTCTACAGAGGGTACAAAGGATTTTCGAGAAAGACGTAAAACGACTGATGGAAAGTTTGGCAGGGTATCAGAATTGATAAGCGAAGAACAAAAAGAAGTTATAGAAACACTTTATCATGTTGACATGACAGTTGtcgataatgaaaaagtttacaaGAATCTTACGGTGCTAGATAGAATCAGTATACGGTGTAACATTTGTAATACGATTTATCCCAGAATGGATAAGTGTCAGGTGCACATATGGGGACATCTCAATATGAAACCTTATCGATGCAGAGGTTGTGAATTTGCTACTGTAACAGTTAGTAATGTACGGTGTCATATAAGGAAGAGCCATCTTAAAATCAAACCTTTCGAGTGTCACCTTTGCGAAAAGAGATATGTCACTGCAGTATTGCTAGAGGAACACTTGAACACTCATACTGGAGCAAAACCTTATAGCTGTAAACTCTGTGATTTCTCTAGTTCCAGCAGACAAGTTTTGAGTTACCACAAAACTACGCATAAGCCCTCCAAGgatGTAACCTGCAATATCTGTGGCAAAGACTTTTACTCAAAAGGCAGAATGCGAGCTCACATGAGCATTCATACCAAGAATAAAAACTTCATGTGTAAATTGTGCTCAACATATTTATGCAATGCAGAAGCGCTTGAAAGGCATTGCCAGAATGTACATTCTCGGGATTATACTTGCAACATCTGTGGCAAGAAAGTCAGATCGAAAAAAGCTTTACATACCCATCAAAATGTACACGCAGCTGCAAAGTATAAATGTTCAATCTGCCCTAATGTATACAAAAGTAGTCACATACTTAAGGAACATCTTTTGAAACACGAGGGTATCAGAAAGTATAAATGCAACATCTGCGAGAAATCTTTTGCCCAACAATCTCACCTCGCAGCGCACATGGCTGTTCACAGCGAAAAGagGTATTTTTGTCCAGGATGTAGTCGACCTTTTAATCGTCATGacaatatgaagatgcacacAAAACGCTGCGAGGCTTTCCTTGCCAATCCAGAACTGAAGAACTTGCTGGCTAAAAGGATCCGAACAAGGTCTTTGGAGAGTACCTCTTCGAATGGTGACTCTTCTCAGACTCTAAACGACAATACGCTTATTACATTGAAGACTGAAACTAATAATGATAAGACTGATgtagatttaaataattgtacatcGAGAGATGCCGAGATATCGGATACCACCGATAtcacaaataataaaaatactgaTGACGATTTGTTGCAATCCAAGGACAATGATATCATCAGGATTGGAGAGGTTGAGATCTTTCCaatcgtggaaaaaaatgCCTTAAACGTTCGTACAAGTGGATCAGTTACCATTATCGAGAATGTACTAGGACCCGAATGTTTTTAA
Protein Sequence
MEVEEEEARICRLCGQCGSIYIDVFGEEGTKRLLGLKIHTKINILIDERDALPKVICVQCLGKLEFVCDFQEECLRTQQLLRDRYNLPTLTDVIQEDDGLSHVVCVRCMGTLEFLCDFHEKCHLTQRELLSAKERQNLETNFNEDCDVDSDKENILPAKVPQKRKVIRIVQSEKSKVQKLNSTTNESLVNFTENENSNCDEKFEQNRNRLSESDSVHSHEDLSSDSEETEMCQSISKSTVPKKNLPEENADSNSVPSYTKLDVVENLGTLKKTEETVKEIIDDQNNVRHNSQNVGKFVDEIICTDTQTEIASNKNNDQEISIVNQKKFTCMENKKLHDSKDNNENSLETRERELQSNQEPMNSNNNPVNHTENESESGTILTDSTKSKAVPVIVKQEKYEYVRLPNEAASCSAEKPKINGTNKPTNTSPPPGDEAEDDIGHHIATSSIASSNSSPSVRESSIDNTEENHDSTENLNTFKEHSMQKDHMTQLRKSVIEMLKNTKSQSSSIEASDDPNDIKMRRRTSNSLNYPSSSDDASLIDISTEGTKDFRERRKTTDGKFGRVSELISEEQKEVIETLYHVDMTVVDNEKVYKNLTVLDRISIRCNICNTIYPRMDKCQVHIWGHLNMKPYRCRGCEFATVTVSNVRCHIRKSHLKIKPFECHLCEKRYVTAVLLEEHLNTHTGAKPYSCKLCDFSSSSRQVLSYHKTTHKPSKDVTCNICGKDFYSKGRMRAHMSIHTKNKNFMCKLCSTYLCNAEALERHCQNVHSRDYTCNICGKKVRSKKALHTHQNVHAAAKYKCSICPNVYKSSHILKEHLLKHEGIRKYKCNICEKSFAQQSHLAAHMAVHSEKRYFCPGCSRPFNRHDNMKMHTKRCEAFLANPELKNLLAKRIRTRSLESTSSNGDSSQTLNDNTLITLKTETNNDKTDVDLNNCTSRDAEISDTTDITNNKNTDDDLLQSKDNDIIRIGEVEIFPIVEKNALNVRTSGSVTIIENVLGPECF