Basic Information

Insect: Cephus brachycercus
Gene Symbol: lola
Assembly: GCA_030142315.1
Location: JARQSX010000427.1:1465352-1471763[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0041 0.3 11.7 7.2 1 20 60 79 60 80 0.93

2 10 0.016 1.2 9.9 2.7 1 23 89 112 89 112 0.91

3 10 6.6e-05 0.0048 17.4 0.1 1 20 204 223 204 225 0.95

4 10 0.00076 0.056 14.1 1.4 1 21 248 268 248 269 0.95

5 10 0.58 43 5.0 0.3 1 13 277 289 277 290 0.90

6 10 0.016 1.2 9.9 1.7 1 21 341 361 341 362 0.95

7 10 0.41 30 5.5 0.5 1 20 373 392 373 392 0.95

8 10 0.018 1.3 9.8 0.1 1 21 537 557 537 558 0.96

9 10 0.55 40 5.1 0.1 1 19 625 643 625 646 0.78

10 10 0.0072 0.53 11.0 0.6 1 21 656 676 656 680 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0041	0.3	11.7	7.2	1	20	60	79	60	80	0.93
2	10	0.016	1.2	9.9	2.7	1	23	89	112	89	112	0.91
3	10	6.6e-05	0.0048	17.4	0.1	1	20	204	223	204	225	0.95
4	10	0.00076	0.056	14.1	1.4	1	21	248	268	248	269	0.95
5	10	0.58	43	5.0	0.3	1	13	277	289	277	290	0.90
6	10	0.016	1.2	9.9	1.7	1	21	341	361	341	362	0.95
7	10	0.41	30	5.5	0.5	1	20	373	392	373	392	0.95
8	10	0.018	1.3	9.8	0.1	1	21	537	557	537	558	0.96
9	10	0.55	40	5.1	0.1	1	19	625	643	625	646	0.78
10	10	0.0072	0.53	11.0	0.6	1	21	656	676	656	680	0.91

Sequence Information

Coding Sequence: ATGAAATCTAAACAGCGCGATCGCTTGGGAGTTAAGCGGTTAAGTAAAAACAAATCTATACACGAGAGTGGCACAGTGGCAAAAATAAATCACGTCGATACAAGAGAAAAAGTTGTTGCGCACTACGGATCGCTCGGGAACTTCAACTGTGTCCAGACGACAGACGACCAGCAGAAACACGCTTGCAGCGCCTGCGGCAAAACGTACAAACACAAACACCATTTGAAAAGGCATCACGACTTCGAGTGCGGAATTGATCCTAAGTTCAAGTGTGCATTTTGCCCTCACAAAACAAGATACAAGAACAGCTTAACGAAGCATATTGTCGCGCGACATCACAAGCTCTGGGGTATTGCGTCGCAGCTTGAAAACAGTCAGCAGCAAACAGAGACAAGTGGCGACGtcgaaaatacgttacaacagCAAACTAACAATTTTCCTTCGTACACGGATCTTACCCACGATCTTTATCCGGCCAATTGGACCGTGCCCACATTGCCATCGACCTCTCGTGAGGATCATTATTTACGTCAACTTCGTTCGATGAGTAAGGACGAATCCTTATCGGATAAGGAGGAATCGAAAAAGCGCGGTTGGGGCCCACGAAAGTATCGTTGCGCCGATTGCGGCAGGACTTTTGCACTTGCCGCATCCTTGACACGTCACAGGTCCTTGGAGTGCAGCGGGCAGTCGTCCCGGACGTCGAAGAGAAACGAATCCTTCGCCAAGAAGTCAAAAGATCACGAGTGCAACAGATGCGATCGttcctataaatttttgaCGTCATTATGGCGTCATCAGAATTTGGAATGCGGCGTGGAGCCAAAATTTGCCTGTCCAGTCTGTCACGTTAGGTTTGCTCAGAAAAAGATTCACGGATGGAACGTCAGAGGATACTTGCACAACTACGGTTCAACGGAGAACGCAGAAGGATCCGTTCAGGCGGTAGGCAGTATGGAAATAGCAGATTTCAAACTTCTGGACAATAAGTCGATAACAGTTGAACCCAGCTACAAGAGACACGTCTGCAGCTACTGCAAGAAAGTCTATCTGCTGAAGAACCTTCTGAAACGCCACATGCAATATTCCTGCGAGATGATACCGAAGAGTGCACAATTCGCGTGTACATTCTGCCCCTACAAAAGCATGTACAAAGCCAACATGGAGAGACACCGTCCTGGTCGTACAAAGCCATGTTCGGACTCGATGCCAGCAACGTTATTATCCAGCGGAACTCGACACGTGTCAGTTGTGACGTCCGAGGACGGATGTTTCAATGCACGGACTGTGGGAAGTCTTATGCGGTTCAAAGGTCACTCTGGAGACATCGTAAATTCGAATGCATCAATTCACGGCCTAAATTCACCTGCGAGCTGTGCCCGTACAAGAGCTCGCACAAGTGAATTCCTTGTGGAGGATTTCGAAGACGAGGACGAGTGCTTGACGAATGACGAGGAGGAGCAGATGTCTAAAGAAAGTTTTGTCAAAGTTATCAAAACGCCGATAACGAACGTCAAGGGAATTTCGGAATTATTCGAAGTGTCGAAGGAGggtgaaattatattaaagtctaatgaaaatcatattcTCACCCTGAAGGATCCGACCTACGAGTGCGAGGCCTGCGGGAAGACGTACGCCTGGGCTACGTCCTTGAGCAGACACCGTAGGGAATGTCAAGAGAGGAAGAAATTGCTTGAGCAAACCGAAGAGATTAACAGCGAAGAAGAAATCATAAAAGATTCCATAGAGAATCCAGGGTCTTCGACGTCGTCTCCTCGGGATGACGAAGATATGGTCCAGGAAGATGCTGTGGCGAAGTACAAGCCACGATTTCGCGAGTTGCAAAAATACGTATCCAAAGATGGCGTATACTCGTGTTGGGACTGCGGCAAGTACTACCTGTGGGCCTCTTCTTTGTCCAGACACAGGACCATCGAGTGTGGAcctaaaaataagaaaagattcGTCTGCAATCTTTGTAATTACCGTACAGGATACAAGGGAAATTTCGTGAGACACCTAAAAGCACCAAGACACATAATGCACAGCAGTttggaaaagaagagaatgcAAATTGCtacgatgaaaaagaagaatgtcAGCGAGGAGGCTGACGAAGAGTTAGAAGAGACAgattccTCAGGATATCAACTAGCAGCCTCCCTATGTCCTCGTAGTAAAGATATTTGTATGCACAGTGCTTAA
Protein Sequence: MKSKQRDRLGVKRLSKNKSIHESGTVAKINHVDTREKVVAHYGSLGNFNCVQTTDDQQKHACSACGKTYKHKHHLKRHHDFECGIDPKFKCAFCPHKTRYKNSLTKHIVARHHKLWGIASQLENSQQQTETSGDVENTLQQQTNNFPSYTDLTHDLYPANWTVPTLPSTSREDHYLRQLRSMSKDESLSDKEESKKRGWGPRKYRCADCGRTFALAASLTRHRSLECSGQSSRTSKRNESFAKKSKDHECNRCDRSYKFLTSLWRHQNLECGVEPKFACPVCHVRFAQKKIHGWNVRGYLHNYGSTENAEGSVQAVGSMEIADFKLLDNKSITVEPSYKRHVCSYCKKVYLLKNLLKRHMQYSCEMIPKSAQFACTFCPYKSMYKANMERHRPGRTKPCSDSMPATLLSSGTRHVSVVTSEDGCFNARTVGSLMRFKGHSGDIVNSNASIHGLNSPASCARTRARTSEFLVEDFEDEDECLTNDEEEQMSKESFVKVIKTPITNVKGISELFEVSKEGEIILKSNENHILTLKDPTYECEACGKTYAWATSLSRHRRECQERKKLLEQTEEINSEEEIIKDSIENPGSSTSSPRDDEDMVQEDAVAKYKPRFRELQKYVSKDGVYSCWDCGKYYLWASSLSRHRTIECGPKNKKRFVCNLCNYRTGYKGNFVRHLKAPRHIMHSSLEKKRMQIATMKKKNVSEEADEELEETDSSGYQLAASLCPRSKDICMHSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00297112;
90% Identity: iTF_00294024;
80% Identity: -