Basic Information

Insect: Cephus brachycercus
Gene Symbol: wek
Assembly: GCA_030142315.1
Location: JARQSX010000810.1:889317-892079[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.2 88 4.0 0.1 2 23 198 220 197 220 0.93

2 15 2.4e-05 0.0017 18.8 1.8 2 23 225 247 224 247 0.95

3 15 0.6 44 4.9 0.0 3 23 308 328 306 328 0.96

4 15 1.6 1.2e+02 3.6 1.5 2 23 334 356 333 356 0.94

5 15 0.00025 0.018 15.6 0.1 1 19 366 384 366 387 0.94

6 15 9.7e-05 0.0071 16.9 8.5 1 23 396 418 396 418 0.98

7 15 0.00013 0.0099 16.4 0.6 1 23 431 453 431 453 0.98

8 15 0.00077 0.056 14.0 5.0 1 23 461 484 461 484 0.97

9 15 3e-05 0.0022 18.5 4.0 1 23 490 512 490 512 0.98

10 15 0.00046 0.034 14.7 1.0 1 23 515 538 515 538 0.96

11 15 0.1 7.4 7.4 1.6 1 23 557 579 557 579 0.95

12 15 0.00082 0.06 14.0 0.8 3 23 587 607 585 607 0.97

13 15 1.3e-07 9.6e-06 25.9 5.3 1 23 612 634 612 634 0.98

14 15 0.00017 0.012 16.1 4.8 1 23 642 664 642 664 0.98

15 15 0.00071 0.052 14.1 0.9 1 23 670 692 670 692 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.2	88	4.0	0.1	2	23	198	220	197	220	0.93
2	15	2.4e-05	0.0017	18.8	1.8	2	23	225	247	224	247	0.95
3	15	0.6	44	4.9	0.0	3	23	308	328	306	328	0.96
4	15	1.6	1.2e+02	3.6	1.5	2	23	334	356	333	356	0.94
5	15	0.00025	0.018	15.6	0.1	1	19	366	384	366	387	0.94
6	15	9.7e-05	0.0071	16.9	8.5	1	23	396	418	396	418	0.98
7	15	0.00013	0.0099	16.4	0.6	1	23	431	453	431	453	0.98
8	15	0.00077	0.056	14.0	5.0	1	23	461	484	461	484	0.97
9	15	3e-05	0.0022	18.5	4.0	1	23	490	512	490	512	0.98
10	15	0.00046	0.034	14.7	1.0	1	23	515	538	515	538	0.96
11	15	0.1	7.4	7.4	1.6	1	23	557	579	557	579	0.95
12	15	0.00082	0.06	14.0	0.8	3	23	587	607	585	607	0.97
13	15	1.3e-07	9.6e-06	25.9	5.3	1	23	612	634	612	634	0.98
14	15	0.00017	0.012	16.1	4.8	1	23	642	664	642	664	0.98
15	15	0.00071	0.052	14.1	0.9	1	23	670	692	670	692	0.98

Sequence Information

Coding Sequence: ATGGATCAAAATGGAATGAAAGTTGATGAGACTGCTTTAGAACCACAGAAGCTCCCTACTgatcataataatattgTGATTGGAACAGATAGCATAGATTTCACTAAATCAAAAACAAGAGACACTCAAAATGTTTGCCGTCTATGTGCACAAAAATGCATAGATTGTGTATCTATTTTTGAAGACAATAATATGTTAATTGCAGAAAAAATTGCTAGATGTCTACCAATAATTGTTTTATCTACGGATGAATtgccattatttatttgcaaacgATGTTTACACTGTTTAAATATCAGTTACAAACTGATTGTTAATTGTTTAAGAGTAGATGCACAGTTGCGAGCGGAGTTTGCACAGTTGAAAAAATCAGACAATACATTAAAGGTATTAGAAGATTtaggaaaatcaaaaaaaattgcattaaaggAATTTGAATCACCAGGAACAATTATAGAAAAGGAGCAGTTGGAACAACTAGAAACGAATTCAAATAGCAATGGAAGATCTGTACAacatatttccataaaaactGGTCAAGCCTCTAAGATAGACAATAAGTTAAAAGAGATTGCTATAAAGGGCCCTGTAGAATGTGAATTATGCTTAAAGCTGTTTCAAGATATGGACCAGTTTGATAGTCATATAGAAAatgtacatttattaaattggcGATGTAATTTATGTGACAAAAGCTTCAAGACTTctacaaaattgataattcaCAAACAATCAAAGCATGCCggcaatattaatatttgcaaaatttgtgTCAAGTCAGAAAAATCTAAAACAGAGTCAGATTCGGACATCTTTGACCTTCCactggtaaataaaaaacctCCATCGCCAGTACAGACTATGAGTACTACAGAAAATCAAAGTGGAAAAGTAATTGCAGAAAATTCATTGGATGTTATTTGCGAAATATGCCATGTTGCTGTGGACGATGATGATCTTCTTGAGGGACATAAAAAGGTTCATCAAcctaaaaaaatgacatgcgTTATATGTCAAACGGAATGCAATTCTGTCTACGATATGTTTCTCCACAAGAGAGAATCCCACAATAAATACAGAAAAGTTCagctgaaatttgtttgtGAACTGTGTGGCAAGTTTTTCTCTAATAGCTGGCAATGGGAAAATCATGAGGAAAATGTCTGTCGTCAAAAATTCTCCGTTCACACGTGCAAATActgcaaaatcaatttttcgacGAACCACAAGCTTACACGGCATTTAAGAaaacataaaaaggaaatgatGGATGATCCCACTGTGACAGTTTATAAATGTGTTGCTTGTCCCAAGGTTTTTGTTGATAAAGAATTCTATCAAAAGCATAGAAATGTGCATGATCCAGAGTGTTGGGATACACACAAATGTACTTTGTGTAATCGTTCATTCAGGGATAATGTAAGACTTAAAGAACACCATCAATCCATACATGAAGGTGTTAAGCCACATCAGTGTGATGTTTGTGGAAGAACATTTCATCGATTATCTAAcatgAGGGCACATCGAATCAAACATTTTGGCCACAAGTGTCCCCACTGCGAAGAAGTATTTGAACGAACTCGTCCTCTTGCAAGTCACATTCAAAATGTTCATGGACTCGAACCTGAGATCAAAGGACAGTCTAAAAGACAATACACTAGTAGCTGTTATGTATGTCGATTCTGtgggaaaaaattatctacgtACCAATCGGTATTGGACCATGAGCATATACATACTGGCGAGAAACCATATGGCTGTAATATTTGTGACAAGAAATTTAGGAGTTATACGTCAAAATGGGCTCATGTGCAAAGACATGAAAAAGGCAATTATGTCTGCGAACACTGTGGAAAATGTTTTAGTTACAAGCAAAATCTCACCACACATATGCAGATACACGCTCCTATCGAGGATCGCAAGCATCGGTGCTCTAAATGTGACAAACGTTTCCTTCGTAAGGCCCATCTCGACGTGCACATGAGAATTCATAATGGTATAAGACCGTACACTTGTGATATATGCTTGTTTAATTTTACGCAATTGGGCGACATGAAAAGACACAGGGCGAGACACGCCAATGGTGAAGTCCGCGTAAGGCAGCCGAGAACTAAATCTATACCAACAACCAGCAACGAGGATACCAATTAA
Protein Sequence: MDQNGMKVDETALEPQKLPTDHNNIVIGTDSIDFTKSKTRDTQNVCRLCAQKCIDCVSIFEDNNMLIAEKIARCLPIIVLSTDELPLFICKRCLHCLNISYKLIVNCLRVDAQLRAEFAQLKKSDNTLKVLEDLGKSKKIALKEFESPGTIIEKEQLEQLETNSNSNGRSVQHISIKTGQASKIDNKLKEIAIKGPVECELCLKLFQDMDQFDSHIENVHLLNWRCNLCDKSFKTSTKLIIHKQSKHAGNINICKICVKSEKSKTESDSDIFDLPLVNKKPPSPVQTMSTTENQSGKVIAENSLDVICEICHVAVDDDDLLEGHKKVHQPKKMTCVICQTECNSVYDMFLHKRESHNKYRKVQLKFVCELCGKFFSNSWQWENHEENVCRQKFSVHTCKYCKINFSTNHKLTRHLRKHKKEMMDDPTVTVYKCVACPKVFVDKEFYQKHRNVHDPECWDTHKCTLCNRSFRDNVRLKEHHQSIHEGVKPHQCDVCGRTFHRLSNMRAHRIKHFGHKCPHCEEVFERTRPLASHIQNVHGLEPEIKGQSKRQYTSSCYVCRFCGKKLSTYQSVLDHEHIHTGEKPYGCNICDKKFRSYTSKWAHVQRHEKGNYVCEHCGKCFSYKQNLTTHMQIHAPIEDRKHRCSKCDKRFLRKAHLDVHMRIHNGIRPYTCDICLFNFTQLGDMKRHRARHANGEVRVRQPRTKSIPTTSNEDTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00252290;
90% Identity: iTF_00252290;
80% Identity: -