Ccan035632.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cenopis cana
Gene Symbol
ZEB1
Assembly
GCA_951800055.1
Location
OX637497.1:9120937-9133519[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 24 0.027 2 10.1 0.3 1 23 96 118 96 118 0.98
2 24 1.3 99 4.8 2.9 2 21 138 156 137 158 0.89
3 24 0.00018 0.014 16.9 0.7 1 23 164 186 164 186 0.98
4 24 0.00011 0.0083 17.6 2.1 1 23 192 214 192 214 0.98
5 24 4.8e-06 0.00037 21.9 3.2 1 23 220 242 220 242 0.99
6 24 0.00027 0.021 16.4 0.3 1 23 248 270 248 270 0.98
7 24 0.00039 0.03 15.9 0.2 1 23 276 298 276 298 0.98
8 24 4.3e-06 0.00033 22.1 2.4 1 23 304 326 304 326 0.99
9 24 1.9e-06 0.00015 23.2 0.8 1 23 332 354 332 354 0.98
10 24 0.0014 0.11 14.1 0.3 1 23 360 382 360 382 0.98
11 24 0.015 1.2 10.9 0.7 1 23 488 510 488 510 0.98
12 24 8.8e-05 0.0067 17.9 2.9 1 23 534 556 534 556 0.98
13 24 3.5e-06 0.00027 22.3 0.3 1 23 562 584 562 584 0.99
14 24 0.0024 0.19 13.4 1.6 1 23 590 612 590 612 0.96
15 24 0.044 3.4 9.4 2.1 1 23 718 740 718 740 0.98
16 24 2.3e-05 0.0017 19.8 2.3 1 23 764 786 764 786 0.98
17 24 0.0025 0.19 13.3 1.3 1 23 792 814 792 814 0.97
18 24 1.2e-05 0.00092 20.7 0.5 1 23 820 842 820 842 0.99
19 24 0.0006 0.046 15.3 0.4 1 23 848 870 848 870 0.98
20 24 0.038 2.9 9.6 2.9 1 23 976 998 976 998 0.98
21 24 9.4e-05 0.0072 17.8 5.3 1 23 1022 1044 1022 1044 0.98
22 24 8.1e-06 0.00062 21.2 1.1 1 23 1050 1072 1050 1072 0.98
23 24 8.1e-07 6.2e-05 24.3 0.6 1 23 1078 1100 1078 1100 0.99
24 24 5.6e-05 0.0043 18.5 0.9 1 23 1106 1128 1106 1128 0.97

Sequence Information

Coding Sequence
ATGGAGGGTAGCGATACCGGCGGTATAACGCTGGCGGCGGTGTACCTGAAAGAAGATCCAGAGGGTGCTATTTGCCATGTAGTATCAAACCTGAATGATGACCTCGTCAATAAGGACCAGTTCGTTTTGGGTCCGGAGCCCATACAGGGGCCCAAAATAGTCAATGCTGTTAACGtggaaaaGCAGAGAGAGCGAGAGATGGAGATACCGAGCCCTGAACTCAAAACTGAACCAGGATCTTATACTTTTACCGACTCGTTTCATCATATTGAGGAGAAAAATACTTATGTATGCGACTCGTGCGGCCAAGTATTTCTACATAAACTTGAGCTAATAGGGCATATAAAATCTCACCTGCGGGAAAACTCAGAATCATTGACAAAAGAGTCAAATTTATTTACTGGAAAAATCTCCTGTAAAATATGCAATAAAAAGTACAGAAAAGATTACATAAAGATTCACGAGCGATGTCACACAGGCGACAAACCTTACTCCTGCGAGGTATGTAAAAAGAAGTTTGCTTTTTTGGGAAATTTAAACGGACATAAACGTATCCACACTGAGGAGAGGCCCTACTCGTGCGACGTATGCAAAAAGAGCTTCATGAGAATGGATTATCTACAGAGGCACAAACTAAGTCACACAGGCGAGAAACCTTATACGTGTAAGGTTTGTAAAAAAGGGTTCACGCAGATATGTAATTTAAAGGCACATATAAGAACTCACACAGGAGAAAAGCCATATGAATGTCCAATCTGTGCAAAGCGGTTTGTGTATATGAGTGGTCTACAGCAACATAAACTGTCGCACACAGGTGAAAAACCATACTCTTGCGAAATATGTAAAAAGGAGTTTATTGCTTTGGGCGAGTTAAAGATACACAAACGAATTCACTCCGGAGAGAAGCCTTATAAATGTGGGGTTTGTAATAAAGGATGCACGCAGATGTCTAATTTAAAGTCACATATGCGAATTCATACAGGAGAAAAGCCTTATGAATGTCCAATTTGTGAAAAGCGGTTTGCGCATAACAGTGCTCTAGCGAGACATAAACAGTCGCACACCGGTGACAAACCATACTCTTGCGAAATATGTAAAACGGAGTTTACTGCTTTGGGCGATTTAAAGACACACAAACAAATCCACTCCGGAGAGAAACCTTATCTGCCACATTCGCTGTTGACAGCTGATAAGGTGGAAGCAACGGAGCCATCCCAAGTGAAAGAGGATCTTAAGTGTGAGAGCAGTACGGCCTCTGTGACCGAGACAGGCTTGTATGCTGACCACGTGGTTAACGATGAGCTTGTGCTGGGGCCGGTAGAGCTACATCGGCGCAAGGAAGACGACATCTCTCGTGaggaAAAGTGTCTAGAGGTCGAGATATTGAGCCCTGAACTCAAAACTGAACCAGGATCTTGTACTTTTACCGACTCCCTTCACCATATTGATCAGAAAAATACTTATGCATGCGACTCGTGCGCCaaagaatttttaaataaacatgatCTAATAGACCATATAAAAACTCACCTACGGGAAAGTTCAGATTCGTTGACAAAAGAGTCTTTATTAACCCGTGAACCCATTTACAAGAAGCCCTATTCGTGCGACGTATGCAAAAAGAACTTCACTAAAATAACTGATCTAAAGAGGCACAAACGAAGTCACACAGGAGAAAAGCCTTATGAATGTCCAATTTGTGAAGAGCGGTTTTCGCAATACAGTGGTCTAGCGAGACATAAACGGTCGCACACGGGCGACAAATCACACTTTTGCGAAATATGTAAAAAGGAGTTTACTGCTTTGGGCGATTTAAAGACACACAAACAAATCCACTCCGGAGAGAAACCTTATCTACCACACTCGTTGTTGACAGTTGATAAGGTGGAAGCAACGGAGCCATCCCAAGTGAAAGAGGATCTTAAGTGTGAGAGCAGCACGGACTGTGTAAGCGAGACAGGCTTGTATGCTGGCCACGTGGTTAAGGATGAGCTTGTGCTGGGGCCGGTAGAGCTACATCGGCGCAAGGAAGACTACACCTCTCGCGagaaTAAGTGTCTAGAGATCGAGATATTGAGCCCTGAACTCAAAACTGAACCAGGATCTTATACTTTTACCGACTCGCTTCATCATACTGATCAGAAAAATACTTATGCATGTGACTCGTGCGCCAAAGAATTTTTACATAAACATGATCTAATAGACCATATAAAAACTCACCCACGGGAAAGTTCAGATTCGTTGACAAAAGAGTCTTTATTAACCCGTGAACCCATTTACAAGAAGCCCTTCTCGTGCGATGTATGCAAAAAGAACTTCACTAGAATAACTGATCTAAAGAGGCAcaaacgaattcacacgggcgagaAACCTTATATATGTGGGGTTTGTATGAAAGGGTGCACGCGGATGAGTGATTTGAAGGCACATATGCGATTTCATACAGGAGAAAAGCCTTATGAATGTCCAATTTGTGAAGAGCGGTTTTCGCAATACAAAGGTCTAGCGAGACATAAACGGTCGCACACAGGCGACAAATCATACTCTTGCGAAATATGTAAAACGGAGTTTACTGCTTTGGGCGATTTAAAGAAACACAAACAAATCCACTCCGGAGAGAAACCTTATCTACCACACTCGTTGTTAACAGTTGATAAGGTGGAAGCAACGGAGCCATCCCAAGTGAAAGAGGATCTTAAGTGTGACAGCAGTACGGACTGTGTAAGCGAGACAGGCTTGTATGCTGGCCACGTGGTTAAGGATGAGCTTGTGCTGGGGCCGGTAGAGCTACATCGGCGCAAGGAAGACGACACCTCTCGTGaggaAAAGTGTCTAGAGATCGAGATATTGAGCCCTGAACTCAAAACTGAACCAGGATCTTATACTTTTACCGACTCGCTTCATCATACTGATCAGAAAAATACTTATTCATGTGAATCGTGCGCCAAAGAATTTTTACATAAACATGATCTAATAGACCATATTAAAACTCACCTAAGGAACAGTTCAGTTTCGTTGACAAAAGAGTCTTTATTAACCCGTGAACCCATTTACGAGAAGCCCTACTCGTGCGACGTATGCAAAAAGAACTTCACTAAACTACATGATCTAAAGAGGCACAAACGAAGTCACACAGGCGAGAAACCTTACATATGTGGGGTTTGTAAAAAAGGGTGCACGCAGATGAGTAATTTAAAGGCACATATGCGAATTCATACAACAGAAAAGCCTTATGAATGTCCAATTTGTGAAAAGCGGTTTTCGCAATATAGTGGTCTAGCGAGACATAAACGGTCGCACACATGCGACAAATCATACTTTTGCGAAATATGTAAAAAGGAGTTTACTACTTTGGGCGATTTAAAGACACACAAACTTATCCACTCCGGAGAGAAACCTTATCTGCCACATTCGCTATTGACAGCTGTTAAGGTGGAAGCAACGGAGCCATCCCAAGTGAAAGAGGATCTTAAGTGTGAGAGCAGCACGGACAGTGTAAGCGAGACAGGCTTGTATGCTGGCCACGAGGTTAAGGATGAGCTTGTGCTGGGGCCGGTAGAGCTACATCGGCGCAAGGAAGACGACATCTCTCGCGGTAAGTTGCTAGGTACTCTGACTAATCATTTACTTTTTCTCGTATATTTATAA
Protein Sequence
MEGSDTGGITLAAVYLKEDPEGAICHVVSNLNDDLVNKDQFVLGPEPIQGPKIVNAVNVEKQREREMEIPSPELKTEPGSYTFTDSFHHIEEKNTYVCDSCGQVFLHKLELIGHIKSHLRENSESLTKESNLFTGKISCKICNKKYRKDYIKIHERCHTGDKPYSCEVCKKKFAFLGNLNGHKRIHTEERPYSCDVCKKSFMRMDYLQRHKLSHTGEKPYTCKVCKKGFTQICNLKAHIRTHTGEKPYECPICAKRFVYMSGLQQHKLSHTGEKPYSCEICKKEFIALGELKIHKRIHSGEKPYKCGVCNKGCTQMSNLKSHMRIHTGEKPYECPICEKRFAHNSALARHKQSHTGDKPYSCEICKTEFTALGDLKTHKQIHSGEKPYLPHSLLTADKVEATEPSQVKEDLKCESSTASVTETGLYADHVVNDELVLGPVELHRRKEDDISREEKCLEVEILSPELKTEPGSCTFTDSLHHIDQKNTYACDSCAKEFLNKHDLIDHIKTHLRESSDSLTKESLLTREPIYKKPYSCDVCKKNFTKITDLKRHKRSHTGEKPYECPICEERFSQYSGLARHKRSHTGDKSHFCEICKKEFTALGDLKTHKQIHSGEKPYLPHSLLTVDKVEATEPSQVKEDLKCESSTDCVSETGLYAGHVVKDELVLGPVELHRRKEDYTSRENKCLEIEILSPELKTEPGSYTFTDSLHHTDQKNTYACDSCAKEFLHKHDLIDHIKTHPRESSDSLTKESLLTREPIYKKPFSCDVCKKNFTRITDLKRHKRIHTGEKPYICGVCMKGCTRMSDLKAHMRFHTGEKPYECPICEERFSQYKGLARHKRSHTGDKSYSCEICKTEFTALGDLKKHKQIHSGEKPYLPHSLLTVDKVEATEPSQVKEDLKCDSSTDCVSETGLYAGHVVKDELVLGPVELHRRKEDDTSREEKCLEIEILSPELKTEPGSYTFTDSLHHTDQKNTYSCESCAKEFLHKHDLIDHIKTHLRNSSVSLTKESLLTREPIYEKPYSCDVCKKNFTKLHDLKRHKRSHTGEKPYICGVCKKGCTQMSNLKAHMRIHTTEKPYECPICEKRFSQYSGLARHKRSHTCDKSYFCEICKKEFTTLGDLKTHKLIHSGEKPYLPHSLLTAVKVEATEPSQVKEDLKCESSTDSVSETGLYAGHEVKDELVLGPVELHRRKEDDISRGKLLGTLTNHLLFLVYL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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