Basic Information

Gene Symbol
-
Assembly
GCA_011634745.1
Location
JAABKK010000464.1:5114-7289[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.86 72 4.8 0.1 3 23 266 287 264 287 0.91
2 9 0.00083 0.07 14.2 2.0 1 23 319 341 319 342 0.93
3 9 2.2e-07 1.8e-05 25.5 1.7 1 23 350 372 350 372 0.98
4 9 0.00014 0.012 16.7 1.1 1 23 380 403 380 403 0.93
5 9 0.0042 0.35 12.0 0.3 2 23 411 433 410 433 0.94
6 9 0.2 17 6.7 1.5 2 23 441 463 440 463 0.96
7 9 0.00061 0.051 14.7 0.1 3 23 469 490 468 490 0.96
8 9 0.011 0.93 10.7 2.9 1 23 501 523 501 523 0.97
9 9 1.6e-05 0.0013 19.7 3.4 1 23 530 553 530 553 0.98

Sequence Information

Coding Sequence
ATGAATAATGGATTTTTATGTCGACTGTGTTTAGACAATTCTGAAGAGACAATTAGTATCTCGAGTGATGAAGCTACACACCTGAATATTGAATCATTgctgattaaatatttttattttgactttgAGcCTGAAAATCAAATTCTTTCTCAACACATTTGTAGAAAATGTTGGATAAAACTGGACagtttcaatcaattttacgAGCTTATTAAATCTGTACATTTGCAAAATTGGAAGCAAAACCACACCGAATTCGTTGAATGTATTGAGCCACCAATTTTAGAAAAAGTTCTCGCATTAGAAGATGTcagcgaaataaaattagaaacaaagaatgtgaataaattttctgagATTTCCACTTATATTGATGATACAAATgctgaaaatagaaatgaaagtAACCATGATAGTTTTAAAGACGATACAGATAAAGTCGATATTCTATATGATACTTTGACATACGATTCTAGCGATGAATCTAACGATGtggaacataaatttaatggtgAAGAGACGGATGACgatgatttaccACTCAGTaaattattgagaaaaaaGAACCTCagcaaaacagaaaatattgtgaaaagtTATGATACAATACGCAACGAAAGAGATAATTACCGATTATGTGATGAATCTGAatcaaattctaaaaataaaattaaactaacaTCAATtcgaaagaaattaaaaaaaaaaactagtgaTAGTTCAACAAGACCAAAATTTATACCTGCCCCAATTGTTCCAgattataatagaattaaatcCATTCTAGATATGAATTGTGAAATTTGTTCAGCACCATTCGATACATTTCCAGATgctacaaaacattttaaagagCTTCATAATCGGTCTGCTTATGTTATGTGTTGTGAGAAACGTTTTTTCAATGTAAATCGTATTATGTCACATATTGAGTACCATGAAAATCCAAACGTGTATAAATGTCAAATATGCGGGAAGGTATTCATCGATTCTCAAATCCTTCGATACCATGTTGCTCATCATCATGCGTCCGACGCTGAAAAAGTATTCACATGCGAAATGTGCACAAAATCATTTGCTACAAAAAGCTTGTTAAATGCTCATCGGCGACGACATCCTACTACTGATGGAACTACATTTGATTGTACGCAATGcgataagaaatttaaaacaattggaTTATTACAACAACATACTTCATATGTCCATTTTCCAACAAAACATCAAATTGTATGCGATGTTTGCGCTAAagtctttaaatataaagatcGATACAGATTACATTACAATTTAGAACACTTAGGTATTGATATGAAAGTTCAATGTGATATATGCAAGCAATGgctCAAACATAAGCGAGTATTAAACAATCATATGAAAAATGTGCATAGTGCACCAGCAATTTGTCAAATGTGTGGCGTAGttgtaaaatcaaaaagaagCCTAACAGATCACATTCGCGAAATTCACAATATACGTCCAAATTCACAAAAATCCATACACACTTGCAATATTTGTAATCATCAATTAAAAGATGCTCAGCGACTGCGGGAACACATGAGCGTACATACTGGGATTACAGATTTGTACACATGCGATTATTGTCCAAAAACGTTTCGTTTTAATTCAGCAATGTGTGCACACCGCAAGAAAGCCCATCCAATCGAATAtgccgaaaatattattaaaaataaattatatcgaaGAGATTTTTCGTATGAATCAATAAACTatgtttaa
Protein Sequence
MNNGFLCRLCLDNSEETISISSDEATHLNIESLLIKYFYFDFEPENQILSQHICRKCWIKLDSFNQFYELIKSVHLQNWKQNHTEFVECIEPPILEKVLALEDVSEIKLETKNVNKFSEISTYIDDTNAENRNESNHDSFKDDTDKVDILYDTLTYDSSDESNDVEHKFNGEETDDDDLPLSKLLRKKNLSKTENIVKSYDTIRNERDNYRLCDESESNSKNKIKLTSIRKKLKKKTSDSSTRPKFIPAPIVPDYNRIKSILDMNCEICSAPFDTFPDATKHFKELHNRSAYVMCCEKRFFNVNRIMSHIEYHENPNVYKCQICGKVFIDSQILRYHVAHHHASDAEKVFTCEMCTKSFATKSLLNAHRRRHPTTDGTTFDCTQCDKKFKTIGLLQQHTSYVHFPTKHQIVCDVCAKVFKYKDRYRLHYNLEHLGIDMKVQCDICKQWLKHKRVLNNHMKNVHSAPAICQMCGVVVKSKRSLTDHIREIHNIRPNSQKSIHTCNICNHQLKDAQRLREHMSVHTGITDLYTCDYCPKTFRFNSAMCAHRKKAHPIEYAENIIKNKLYRRDFSYESINYV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-