Basic Information

Gene Symbol
-
Assembly
GCA_944567795.1
Location
CALYMS010000059.1:194847-197521[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.19 11 6.8 0.7 2 23 27 49 26 49 0.93
2 20 0.0011 0.065 13.8 2.0 3 23 122 142 120 142 0.95
3 20 0.41 24 5.8 3.2 1 21 146 166 146 169 0.96
4 20 0.34 20 6.0 0.3 1 21 174 194 174 195 0.90
5 20 0.01 0.6 10.8 0.7 1 23 202 225 202 225 0.95
6 20 0.0052 0.31 11.7 0.9 1 23 232 255 232 255 0.95
7 20 0.62 36 5.2 0.2 1 20 260 279 260 282 0.89
8 20 6.3e-06 0.00037 20.9 2.6 1 21 288 308 288 309 0.95
9 20 0.021 1.2 9.8 0.3 3 23 356 377 355 377 0.98
10 20 0.13 7.8 7.3 0.4 2 23 402 424 401 424 0.95
11 20 0.0021 0.12 13.0 0.1 2 23 448 469 447 469 0.95
12 20 3.4e-05 0.002 18.6 0.4 1 21 473 493 473 494 0.96
13 20 0.031 1.8 9.3 0.3 1 23 535 558 535 558 0.95
14 20 0.71 42 5.0 1.2 2 23 584 606 583 606 0.94
15 20 0.01 0.6 10.8 1.5 2 23 630 651 629 651 0.95
16 20 0.00022 0.013 16.1 0.0 1 23 655 678 655 678 0.97
17 20 0.043 2.5 8.8 0.6 1 23 682 705 682 705 0.97
18 20 3.1 1.8e+02 3.0 0.3 1 23 710 735 710 735 0.89
19 20 0.00024 0.014 16.0 2.5 1 23 744 767 744 767 0.97
20 20 0.00047 0.027 15.0 0.6 1 23 777 800 777 800 0.96

Sequence Information

Coding Sequence
ATGAAGGCGAAACTGAACGCCGAAATCCTATTGAAATATTCAACGGCATACCCGTTTAGGCTGAACGGGAACATGCTGATGTGCGTGTACTGCTGCGAGGAGTACCGCGGCCCGGGGGAGTACCGGCGGCACATGCGCGACAGCCACGCCGCCTTCACCGTGGCCACCGCCTTCTCGCACGCGCGCTGCGTGGACTACATCAAGGCCGACGTGACCGAGCTCGCGTGCCGGCTgtgcgccgcgcccgcccccgaCCTGCAGTACATGGGCCGCCACCTCAGGGACGCGCACGGCAACCGCGACATCGACCTCGACCACCCCATCGGCATCCACCCGTACAGTATCCACAGCGACAGGTGGAACTGCGCGCTGTGCGACAAGAAGTTCGCGACGCTGACGAAGCTGTGCAGGCATACCGCTTCGCACTATCGCAAGTATACGTGCGAAGTCTGTGCGCGCTGCTACCTGACGAAGGAGGCGTTGGCTTATCACATGCGCTGCAGCCACGCGAGCGGAATGCACGTCTGCAGGAAGTGCTGGAGGGAGTTCCCGACGGCCGAAGCGAAGAGGGAGCATGCGAAGAAGTCGATGTCGTGCTGGACGTTCTGCTGCGTTCTGTGCGGAGAGAGATTCATGTCGTGGGAGGCCAAGCAGAAGCATCTGGTGACCGTGCACGACCGACCGAAGCACACGTACTCGTGCCCCGACTGCGGCGAGCTGTACGACTCGCGCAAGCAGTACTACCAGCACTACACGATCAAGCACACGGACGACGTGTTCGTGTGCGCGTGCTGCGGCCTCAAATTCCCCAACCAGGGCCTGCTGGACGACCACCTGCCCGTGCACTCCAACGAGAAAAAGTTCCAGTGCAATGTGTGCTCCAAGTGTTTCACCAGGAAGAAAAGCCTCAACCAACACATATTGGAAATACGCGGACGTAATGAGAGTGAGACTGAGAGAAAGAAAATAGTACTAGTGTGCCAGCCGCCGCAGCGGCGGAACGCAGAGTTGATACTTAGGAGCTCGACCGCGTACCCCTTCAAAACCAGGTTTAGCCAGATCCTCTGCGCGTACTGCCACGAGGAGTACGACGCCCTGGCCGATTTAAGATACCACATGAAAACCGAGCATCAAAATTCAGATTTCAAAAACGTTTTCTTTAGAGCCAAGGACAATTTAATCAAAGTGGACATTACCGGTTTGAGATGTAAGATTTGCGATCTAGAAATACAAGACGTGGACAGTCTCATGCACCACTTGTCGCGCGAACACAATAAGCCGGTTAAGTTCAACGAGCGCTTCGGCGTGCTGCCGTACAAGCAGAACGAGGGGAACCGCTGGGTGTGCGTGTACTGTCAGAAGGTGTTCGAGGAGTTCGTGCAGTTCAAGCGGCATATAGGAGTACACTTCATGAACTTTAGCTGCGAGAAGTGCGGGACGATGTTCGTGACCGCTCACGCGTTGCGCGACCACCAGCGGCAGGTCAAGTGCTTCCGCACGGCGTATAAAGCTCGGAACGGAAGAGTTCTCAAACCCAGGACCAACGCCGAGATCATCCTGCAGTGCTCCACCGCTTGCCCCTTCAGAACGTGGATGAACAACTTCAACTGCGTGTTTTGTAGAGTACAATTCAGCGAGCCGATGGCACTCAGGAGTCACATGGCCAGCAGACACGAGAACTACGACGTGCAGGCGGCCTTCTACAAGAAACTCGGTAAGGAGTTTCTCAAAATTGACGTCACGGATCTCAGTTGCAAGCTCTGCTTCATGCCCATCGAAAATTTCGAATCTCTCACTCACCATCTCAAAAATGATCACCAGCAGCCCATAAACTTGGACGCCCAGCTGGGTGTCTTACCATTCAGACTTAACGATGGCTCCAAGTGGAAGTGCACCATGTGTACGAATGAGTTCAAAGACTTCGTCTCCCTCAAGAAACACACCTCGGAGCACTTTCAGAACTACGTGTGCGACACTTGCGGCGAGGGGTTCATTACCGAGTCGGCGATGATCGCGCACACGAAGGTCCCGCACGAGAACAAGTACAACTGCAGCAGATGTGTCGCGACGTTCTCGTCCTTGGACGATCGGAATCTACACGTCAAGACTCAGCACACCTCCACGCCTTACATGTGCGTGTACTGCAAGGACAAGCCGCGGTTCGCGAACTGGGAGCTCCGCAAGAAGCACCTGATGGAGGTTCATAACTTCAAGACTGGCGCGGACAAGTACGAGTGCTCCACTTGCCAGAAGTCGTTCAAGACTCGCTCGGGGAAGTACAACCACATGGCGAGGACGCATCGAATTAAAAAGGATACAGAATTGAATTACCCGTGCAATAGTTGTCCGAAGGCGTTTACGACGAAGCTCTTTTTAGATAAACATATCGCAAAGAAACATTTCGATTGA
Protein Sequence
MKAKLNAEILLKYSTAYPFRLNGNMLMCVYCCEEYRGPGEYRRHMRDSHAAFTVATAFSHARCVDYIKADVTELACRLCAAPAPDLQYMGRHLRDAHGNRDIDLDHPIGIHPYSIHSDRWNCALCDKKFATLTKLCRHTASHYRKYTCEVCARCYLTKEALAYHMRCSHASGMHVCRKCWREFPTAEAKREHAKKSMSCWTFCCVLCGERFMSWEAKQKHLVTVHDRPKHTYSCPDCGELYDSRKQYYQHYTIKHTDDVFVCACCGLKFPNQGLLDDHLPVHSNEKKFQCNVCSKCFTRKKSLNQHILEIRGRNESETERKKIVLVCQPPQRRNAELILRSSTAYPFKTRFSQILCAYCHEEYDALADLRYHMKTEHQNSDFKNVFFRAKDNLIKVDITGLRCKICDLEIQDVDSLMHHLSREHNKPVKFNERFGVLPYKQNEGNRWVCVYCQKVFEEFVQFKRHIGVHFMNFSCEKCGTMFVTAHALRDHQRQVKCFRTAYKARNGRVLKPRTNAEIILQCSTACPFRTWMNNFNCVFCRVQFSEPMALRSHMASRHENYDVQAAFYKKLGKEFLKIDVTDLSCKLCFMPIENFESLTHHLKNDHQQPINLDAQLGVLPFRLNDGSKWKCTMCTNEFKDFVSLKKHTSEHFQNYVCDTCGEGFITESAMIAHTKVPHENKYNCSRCVATFSSLDDRNLHVKTQHTSTPYMCVYCKDKPRFANWELRKKHLMEVHNFKTGADKYECSTCQKSFKTRSGKYNHMARTHRIKKDTELNYPCNSCPKAFTTKLFLDKHIAKKHFD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-