Basic Information

Gene Symbol
-
Assembly
GCA_944567795.1
Location
CALYMS010000267.1:176937-182873[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 36 0.0038 0.22 12.2 2.8 1 23 37 59 37 59 0.98
2 36 0.26 15 6.4 1.0 1 23 129 152 129 152 0.90
3 36 0.0025 0.15 12.7 1.7 2 23 159 181 159 181 0.96
4 36 0.06 3.5 8.4 3.7 1 23 185 208 185 208 0.91
5 36 0.051 3 8.6 0.2 2 23 211 233 211 233 0.95
6 36 0.14 8.3 7.2 0.2 2 20 239 257 238 259 0.91
7 36 0.13 7.6 7.3 0.9 1 23 326 348 326 348 0.94
8 36 0.02 1.2 9.9 0.1 2 23 376 398 376 398 0.92
9 36 0.18 11 6.9 0.6 2 23 419 441 418 441 0.96
10 36 0.017 1 10.1 2.1 1 23 446 468 446 469 0.96
11 36 0.0083 0.49 11.1 2.8 1 23 473 496 473 496 0.93
12 36 0.021 1.2 9.8 2.4 2 23 499 521 498 521 0.95
13 36 2.1 1.2e+02 3.5 0.8 2 20 527 545 526 547 0.88
14 36 0.0013 0.078 13.6 3.0 1 23 595 618 595 618 0.96
15 36 0.00091 0.053 14.1 0.2 1 23 690 713 690 713 0.89
16 36 1.8e-06 0.00011 22.6 0.5 1 23 718 741 718 741 0.95
17 36 0.00014 0.0081 16.7 1.4 1 23 746 769 746 769 0.97
18 36 0.011 0.64 10.7 0.3 2 23 775 797 774 797 0.93
19 36 0.0001 0.0058 17.1 2.5 1 23 801 824 801 824 0.97
20 36 0.22 13 6.6 1.1 2 23 831 852 830 852 0.96
21 36 0.052 3 8.6 2.3 1 23 858 880 858 880 0.96
22 36 0.00022 0.013 16.1 0.7 1 23 922 944 922 944 0.96
23 36 0.028 1.6 9.4 0.1 3 23 973 994 971 994 0.90
24 36 0.0012 0.071 13.7 0.3 2 23 1015 1037 1014 1037 0.97
25 36 1.6e-05 0.00092 19.7 1.3 1 23 1042 1065 1042 1065 0.97
26 36 3.3e-05 0.0019 18.6 0.2 1 23 1070 1093 1070 1093 0.98
27 36 0.016 0.95 10.2 1.6 2 23 1096 1118 1096 1118 0.96
28 36 0.0018 0.11 13.2 1.4 3 22 1126 1145 1125 1145 0.97
29 36 0.00068 0.04 14.5 2.8 1 23 1200 1223 1200 1223 0.95
30 36 0.00068 0.04 14.5 0.4 2 23 1296 1318 1295 1318 0.94
31 36 4.3e-05 0.0025 18.3 0.1 3 23 1325 1346 1324 1346 0.94
32 36 0.01 0.59 10.8 2.9 2 23 1351 1373 1350 1373 0.93
33 36 0.0028 0.16 12.6 2.7 1 23 1378 1401 1378 1401 0.95
34 36 1.9e-05 0.0011 19.4 4.9 1 23 1405 1428 1405 1428 0.97
35 36 0.0016 0.092 13.4 0.3 2 23 1435 1456 1434 1456 0.96
36 36 1.4e-05 0.00083 19.8 2.2 1 23 1462 1484 1462 1484 0.98

Sequence Information

Coding Sequence
ATGAGCGAAAGGGTCGCCCTTGGTCGGGATGCAAATCGTCGGAGAAGACAAAACCTTGAAATTCTATTCAACAACACGAGTATCATACCTTTTAAAGGTCGAGGAAGCTTTAAATGTTTCTATTGCGGCAAAGCAGTAATAGAGTATCATGAATTTAGGAAACACACAATAACACACAACCCTTGCTCGATACACGATCGTGCGATTAAAGTAGTGAAAACAGACGAGGCTGAAGTGAGAGTGGATGTATCTGTAATTAAATGTGAAATATGTAACGAGGCTAAAGATAATTTCGACGGATTAGTCGATCACTTGATAGATGAACATAGTTTGATGTACGACAAGGAGGTAAAGTTGTTAATTGTAAAGTATAAACTGGATGGATTCGATTGTGTCATATGTGATCAGCACTGTACGAGTCTCATAGAACTGCTTACTCACGTGAGTGATGATCACGATAAGACCAAGATTAATTCTTGTACGGAGTGTCGCCAAAAGTTTAGGAAAAAGGGGGAGTTAGACGCACACACGAAAACCTATCACAAGAAGGAGTATAAGTGTTCTAAATGTTCCCTGAGTTTCCCGTCGTACTTCGAACTACACAATCATAACAGTAACTCGCATATCGCGACTTGTAACATCTGCTTTATACCCTTTCCTACGGCTAAGAAAATGCTGCAGCATTTGAAATTGGAACACGGCGATGACGATTTACGTTGCGGCTTCTGCGACAAAGTAGTGAGCACGAAAATTGGCTTTTTAAAACACGCGTCCAAATGTACTGAGATGGAGAAGAAGCATTCGCAAGAGCAATTAGACGATTTCGAACGTCGCGAATTTGCGGGCGCATATACACAAGCATCACAGACCAACGATGTTGTCGGACCGGCACGAACGCACAGTTATAATAGGCGAAGGAATCTTCAGATATTGTTCAACAACACGTCCCTCTGTCCTTTCAAATGGCGAGGCAAATACCTGTGTTTTTTCTGTGGAGAAGACATATCGCATTACGATGAGCTAAAGATACATACGAAAGGTCACATTCCTTGCTCAGATAAAGATAGAGCCATACTGCTAGTTAAAGCTGTCGATGCGGAGGTTAAAATCGACGTGTCCGATAACACTTGTGAAATATGTAACGAATCGTTCTCGAAGTTAGACGATATTGTCGATCATTTGATAGAAAAACACGAACTGCCTTACGACAAGGACGTGAAACTTTCTCTTGCAGTTTATCGCCTCCTCGACTTGCAGTGCTTGCTTTGTGACGAGAAATTCGATTACTTCAACAGGCTTGTCTCCCACGTTAACACCAGGCACCCGAGCGAAAGCTTCGAATGCTCGCAATGTCTtcaaatattcaataaaaaacgGGACATGGACGCTCATTTGCGAATGCATCATAGGAACGAACATAATTGCTCTAAATGTTCGCTATCGTTCACTTCGTATGCCTCTTTCAAGACGCACATCGCGAATTCTCATATATCGACAtgcaatgtttgttttaaaagtttttcatCGCTGAAAAGACGATTGAAGCACATGAAATTGGAACACGCAGATGACGTACTCGAATGCGGTTTCTGCTTCAAGACGATGAGCACGAAGCAAAGCTTTCTGCGCCACGCGACCAAATGCAACACCAGAATAAAGAACGTCGATGAGATTCCCGTGGAAGATGATGAAAAAAAGCCATCCGTCCATCAAATCAGGAATAACGTAGCGTGTATCCTTAACATGTCCACTGCGATACCTTTCAAATACTTTATGAGTAGGTTCAGATGTTTCTATTGCCCGAAAGACTTTAACGAATGCTCCGATTTGAGGCAGCACACGGTTACAGAGCACCCGCATTGCGACATCAAACTCAAAAGCATGAAACTTCGTAACCGGCATGACGGTTGCATCAAAATAGACATAGCATCTCTTTCTTGCAAGCTGTGCATATTGCCCATGCAAAGCTTAGAAGCTTTGATAGAACATTTAGTAACTAATCACAAGGCCCGATACGACAAATCCATCGACTGCAACATGCAGCCCTACAAGTTGATCAAGGATAATTTCGCTTGCCCCCTATGTGGCGAAGTCTATAGATACTTCAGTTCGTTGCTGAGACACGTCGGTAACTTTCACACTGACAATAAGTACATTTGTGTCTACTGCGGTAAATCATTCAGGAACGTGTCGAACTTACGCGCCCACGTCTCCAGTAAGCATAACACGGCGGTGTATAAGTGTAGCAAATGTGATATGGAGCTGACATCAAATAGCCATTTACAGACGCACTTGGGCACCGCCCACGGAGCTAAGGTCATTCAGTGTTTAGAGTGCGAAGAGAAGTTCATATCGAACTATAGGATGCAGAGACACATGGTCAACGTTCACAGTTCGGGGCACAAGTGTGCGTATTGTGGGAAATTATTTACGAGAAATTCATTGATGGTGAATCACGTAAGGCGGACACATCTAAAGGAGAAGAATGTTGAGTGCTCAGTTTGTTTCGAAAGATTTTTTGACGGGCATCGTCTCAAAATACACATGGTGAAACATTACGGGGAGCGAAATTTTCACTGCGACGTTTGCGGCAAAAAGTTTCTGTGGAAGAAAAACTTGCGCGGTCACATGTCGTCTCATATCAAGAAGACCAATGATATCCCGTTTGACAAGTACGAGAACTACGCCTCTCAGAAAAGGAGAAAAAATTTGACATTCCTCTTCAACTATACATCCATTATGCCGTTTAAATGGCGCGGCAAGTACATATGCTTTTACTGCGGAAAGTACTTCGCGGATTATCCTGAGTTAAAAAAGCATACGGTATCTCATGGTATCTGCACCACCAAGGATAACGCGCTAAAACTTATCAAAGGATCCAAAACggaaataaaaatagatatcTCTGAAATTAACTGTAAAATATGCAATGAACCTTTCACGTCTCTGGATGAGATTGTCACTCATCTCGCAGGGAAACACAGTTTGGAATACGATAAATCAGTAGAAATCGCTTATCAGGAATATCTTCTAGCCGATTCACGATGTCAATACTGCGGTGAACAATTCGAGTATTTACGTTTTCTCATAAGCCATATAAACACTGCTCATCCGCAGAATTGTTTCACGTGCGATGATTGTGGACAAAGCTTTAATAAGAAGCAGGATTTGTCGTATCACATTAGACAGAATCACCGCCAGGGCGGCTACCCTTGCGACGAATGCCCAGAGGCATTCGATTCCCAAGTCCTGTTGCGTAGGCACAAAAACACCTACCACTTTAGGAAGTGTAAAACCTGCCAATCCAGATTCGCGTCATTCACTCTCCTCCAGAAACATATTCAACTGGAGCATTCTCTCGGCGGTATTAAGGCCTGTCCGCATTGCGAAAAAGAGTGTCGCTCGCGGCAAGGTCTGGTACAGCATATGCGTACTTGTAAAGTTAAAATCATTGTGAAAAGAGACAAGCCAGTTGTTACCTTCCCGTCCAAGTTGATATTGATGCCGAGAAAAACGCAAAACATATCGCAAATACGACAAAACATTGTCTGCGTCCTAAACATGTCCACGGCGATACCGTTTAAGTTTTTCGCGAAGTTCTCTTGTTTTCACTGCTCGAAAAAGTTTTCGGACTTCGACGAACTCAAGGAGCACACGGCAATGGAACACCCCGTATGCGATCTTAAATCTAAATGCATCATGAAATGTAAAGGAGAACGCACTTGCGTTAAGGTGGATGTGACTACTTTGAAGTGTAAAGTCTGCTGTCAGTCAATGGAGGACCTCGACGCATTGATCGAACATTTGATAAGCAACCACAAGGCGAATTACGACAAATCTTACGCGGAATGCTTCGAGCCTTTCAAGTTGGTCAAGGACAATATTCCATGTCCGCATTGCTCAAGCGTATTCAGATATTTCTCAACGCTCATTCGGCACATAAACGCGGAGCACAGCAATAATAAGAGGATATGCGATTTTTGCGGGAGGGCATTCAAAAACGCTGCCAACTTGAACGTCCACATAAGCTATACCCACAGTGGGTCTTGCGAATGCGAGGTTTGCGGTCTCAAGTTCAAGAACCAGTGGTGTCTCGGCCGGCATAAGGCGAAGATCCATGACGCCAAAGACTTCAAATGCCCGAAGTGTCCCGAGCAGTTTCAATCACAGTATCACAAGCAGAAGCATCTGATTCAGGTCCACGACATCGGCCACAAGTGCAGTTACTGCGGGAGAATGTTCACTAGGAACTCGTTCATGAAAGACCACATAAGACGCACGCATTTGAAAGAGAAAAATGTGCCATGTTCCGTCTGCAGTGAGAAGTTTTTCGATAATTACTTGTTGAAACTTCATATGGTGAAACACGATGGGGAGAGGAAGTTTACGTGCAATGTCTGCGGTAAAGCCTTTCTGAGGAGAAGCAACTTGTGCTCTCATATGGATATGCATAAGAAGTACGGACACGTCCAAGCTCAGATTTGA
Protein Sequence
MSERVALGRDANRRRRQNLEILFNNTSIIPFKGRGSFKCFYCGKAVIEYHEFRKHTITHNPCSIHDRAIKVVKTDEAEVRVDVSVIKCEICNEAKDNFDGLVDHLIDEHSLMYDKEVKLLIVKYKLDGFDCVICDQHCTSLIELLTHVSDDHDKTKINSCTECRQKFRKKGELDAHTKTYHKKEYKCSKCSLSFPSYFELHNHNSNSHIATCNICFIPFPTAKKMLQHLKLEHGDDDLRCGFCDKVVSTKIGFLKHASKCTEMEKKHSQEQLDDFERREFAGAYTQASQTNDVVGPARTHSYNRRRNLQILFNNTSLCPFKWRGKYLCFFCGEDISHYDELKIHTKGHIPCSDKDRAILLVKAVDAEVKIDVSDNTCEICNESFSKLDDIVDHLIEKHELPYDKDVKLSLAVYRLLDLQCLLCDEKFDYFNRLVSHVNTRHPSESFECSQCLQIFNKKRDMDAHLRMHHRNEHNCSKCSLSFTSYASFKTHIANSHISTCNVCFKSFSSLKRRLKHMKLEHADDVLECGFCFKTMSTKQSFLRHATKCNTRIKNVDEIPVEDDEKKPSVHQIRNNVACILNMSTAIPFKYFMSRFRCFYCPKDFNECSDLRQHTVTEHPHCDIKLKSMKLRNRHDGCIKIDIASLSCKLCILPMQSLEALIEHLVTNHKARYDKSIDCNMQPYKLIKDNFACPLCGEVYRYFSSLLRHVGNFHTDNKYICVYCGKSFRNVSNLRAHVSSKHNTAVYKCSKCDMELTSNSHLQTHLGTAHGAKVIQCLECEEKFISNYRMQRHMVNVHSSGHKCAYCGKLFTRNSLMVNHVRRTHLKEKNVECSVCFERFFDGHRLKIHMVKHYGERNFHCDVCGKKFLWKKNLRGHMSSHIKKTNDIPFDKYENYASQKRRKNLTFLFNYTSIMPFKWRGKYICFYCGKYFADYPELKKHTVSHGICTTKDNALKLIKGSKTEIKIDISEINCKICNEPFTSLDEIVTHLAGKHSLEYDKSVEIAYQEYLLADSRCQYCGEQFEYLRFLISHINTAHPQNCFTCDDCGQSFNKKQDLSYHIRQNHRQGGYPCDECPEAFDSQVLLRRHKNTYHFRKCKTCQSRFASFTLLQKHIQLEHSLGGIKACPHCEKECRSRQGLVQHMRTCKVKIIVKRDKPVVTFPSKLILMPRKTQNISQIRQNIVCVLNMSTAIPFKFFAKFSCFHCSKKFSDFDELKEHTAMEHPVCDLKSKCIMKCKGERTCVKVDVTTLKCKVCCQSMEDLDALIEHLISNHKANYDKSYAECFEPFKLVKDNIPCPHCSSVFRYFSTLIRHINAEHSNNKRICDFCGRAFKNAANLNVHISYTHSGSCECEVCGLKFKNQWCLGRHKAKIHDAKDFKCPKCPEQFQSQYHKQKHLIQVHDIGHKCSYCGRMFTRNSFMKDHIRRTHLKEKNVPCSVCSEKFFDNYLLKLHMVKHDGERKFTCNVCGKAFLRRSNLCSHMDMHKKYGHVQAQI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-