Basic Information

Gene Symbol
-
Assembly
GCA_014607495.2
Location
CP053149.1:2846513-2865295[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 5.9 4.6e+02 2.2 0.5 5 23 298 318 296 318 0.89
2 17 0.0011 0.084 14.0 2.9 2 23 571 593 570 593 0.94
3 17 0.0095 0.74 11.0 0.0 1 23 599 621 599 621 0.96
4 17 0.081 6.3 8.1 0.1 1 20 1085 1104 1085 1108 0.88
5 17 1.3e-05 0.001 20.0 5.9 1 23 1113 1135 1113 1135 0.98
6 17 5.6e-05 0.0043 18.0 1.7 1 23 1141 1163 1141 1163 0.97
7 17 4.6e-05 0.0036 18.3 2.8 1 23 1169 1191 1169 1191 0.98
8 17 6.7e-07 5.2e-05 24.1 0.9 1 23 1197 1219 1197 1219 0.99
9 17 0.015 1.2 10.4 2.3 1 23 1225 1247 1225 1247 0.99
10 17 0.003 0.23 12.6 0.3 1 23 1274 1296 1274 1296 0.98
11 17 3.9e-06 0.0003 21.7 3.5 1 23 1302 1325 1302 1325 0.98
12 17 3.9e-06 0.0003 21.7 3.5 1 23 1348 1371 1348 1371 0.98
13 17 3.9e-06 0.0003 21.7 3.5 1 23 1537 1560 1537 1560 0.98
14 17 3.9e-06 0.0003 21.7 3.5 1 23 1811 1834 1811 1834 0.98
15 17 3.9e-06 0.0003 21.7 3.5 1 23 1902 1925 1902 1925 0.98
16 17 3.9e-06 0.0003 21.7 3.5 1 23 2003 2026 2003 2026 0.98
17 17 7.7e-06 0.0006 20.8 3.6 1 23 2049 2072 2049 2072 0.97

Sequence Information

Coding Sequence
ATGGAAGTTTCTCTTTATAATTCTTCTGTATGTAGACTATGTGGAGAAGAAAATGATAATGGAACACTATTATTTACCTGTGAAGAAAATAATCAAAGCCTTAGTGAAATGATTAATGGCTATTTGCCACTTAAGGTATCTGATGATGGTGCCCTGCCACGGACCATCTGTCCAGGATGTACAATTCAACTGGAGGCTACTGTGGAGTTCTTAGACCTAATCATCAAAGGGCAAAAAGTTATTCGAAGACTGTACCTCAGAGAAAAAGAATATAGAAAAAATTTAGTCCATCCACAAGAACAACAAGAAATAAACTTAGAGACAGAAAAAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAACAGTCACATAAACCCAGAAAATGGAGTCTACCAAGCAGAACACCCTGTTTCTCTCCAAGCAGCCGGATTGGACAAGCCTAAGCGTAAACGAGGACGGCCACCCAAGCCAAAACCAACTCCACACGATATTGAGAAGGAGGTGGAAATACAGAGAGAGATCATTGAAAAAGAGAAAGTAAATGAGGAGCCATCTGGAAAGAGAAGAAGGAGAACTCCAAATAGATATAAGGAAGCTGTACAGGGCAAGGAACTAGAAAAGATATTCCTAGAAGAGGGTGTGATAGACGACGACGATGTGGACAAAGAGTCGTCGCAGTCCGAGCCAGGCAAGGGAAGAGGTCGGCCTAAAGGCCGCACGCGTCCAACACACGAGCAGTGTGCAATCTGCGGCATGAATTTCACATGCGTGGGGCGGTACATGTCGCACGTGGCGGCGCACGGACCGGTGTCGTTCCGCTGCGAGTGCGGCTTCCGGTCCGACACACGTCTGCAGCTCAACGAGCACCAGCGTGTGCGCGGACACCGGGGGCACACCGCCACCACGCCGGGGGTACGTACACACCGGGGGCACACCGCCACCACGCCGGGGGTACGTACACACCGGGGGCACACCGCCACCACGCCGGGGGTACGTACACACCGGGGGCACACCGCCACCACGCCGGGGGTACGTACACACCGGGGGCACACCGCCACCACGCCGGGGGTACGTACACACGGGGGCACACCACCGCCACCACGCCGGGGGTACGTACACACCGGGTGCCCACCGCCACACGGGGGGTACGTACACCACACCACGCCGGGGGTACGTACACACCGGGGGCACACCGCCACCACGCCGGGGGTACGTACACACCGGGTGCACACCGCCACCACGCCGGGGGTACGTACACACCGGGGGCACACCGCCACCACGCCGGGGGTACGTACACACCGGGGGCACACCGCCACCACGCCGGGGGTACGTACACACCGGGGGCACACCGCCACCACGCCGGGGAAGGTGCCAGCGAAAGAGCAGCCAAAACCAGAACCTGTCGTAGAAGCAGAACCCGAGCTGCCCTCAGTGGAGAAGATCGTGGACAATGTGCTCATGACGGAGATGCCGGACATGCCGGGCATGCCGGACATGCCGGGCATGCCGGACCTCACGGACCCGCTCAAAGACGACAGTACGGACCCGCTGGGTCTCACGCCCAAGATGGAAAACGAAGCTCCATTGGAAGCTCCCACCGAGTCTGAAGATAAGCCAGCTGCACCCGAGAAACGCAGGCTGAAGTGTAACCACTGCGATAAGACGTTCAGCAATAAACAGAGCAAGTCACTGCATATTAAGGCGGTACATCTAGGCGTGCGTCCGTACGCATGCGCAGAGTGCGGCGCACGCTTCGCCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTACGTCTACCCGCGCTCACTCGCACTGCACGCGCTGTCGCACCGCCGCCGCCGCCTCAAGCAGGGCTACGCGTGCGACCTGTGCGGCAAGGTGCTAAACCACCCATCATCCGTGGCGTACCACAAGGTAGCGGAGCACGCCGGCCAACGCTACGTGTGCAACAAGTGCGGGAAGCACTTCAAGCACAAGCAGCTGCTGCAGAAGCACCAGCTGGTGCACTCACACTCGCGCCCCTACCATTGTCAGGAGTGCTCGGCGTCGTTCAAGACGAAGGCGAATCTAATCAACCATCAGATGTTACACTCGGGCGTCAAACGCTTCTCGTGCGAGATCTGCAAGCAGAAGTTCGCGCACAAGACTAGTCTCACGCTGCATATGCGGTGGCATACCGGTTTAAAACCATACCAGTGTAAGGTCTGCGACAAGCGCTTCAGCCAGAAAGGCAACCTATCGGAACACGAGCGCATCCACAGCGGAGACAAGCCGTACAAATGTGGAGTGTGCGCTTGGCGCTTCACCACCTCCTCACAGCACCGCCTGCACGTGCGCCGCCACGACCGCGCCGCGCCGCCGTCCGCGCCCTCCGCGCCGCCCGCGCCCGCCCGACCCAAAGCGGTGCGTCGCGCGCGCTCATTCGTGTGCGGAGTGTGCGCGCGCGCCTGCGGGGACCGCTGGGCGCTCAGCAAACACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACACCGCTGGGCGCTCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACACCCGCTGGGCGCTCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACACACACACACACCGCTGGGCGCTCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACACACCGCTGGGCGCTCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACACACCGCTGGACGCTCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACACGCTGGGCGCTCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACACCGCTGGGCGCTCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACACCGCTGGGCGCTCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACACCGCTGGGCGCTCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACACCGCTGGGCGCTCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACGCTGGGCGCTCAGCAAGCACATGCGGAGACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACCGCTGGGCGCTCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACACGCTGGGCGCTCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACCGCAGGGCGCTCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACACGCCGGGTCAGTCACACACACACACACACACACGCTCAGCAAGCACATGCGGAGGGGGAGAAGCCGTTCCGCTGCGCGCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGGTCAGTCACACACACACACACACACACCGCAGGGCGCTCAGCAAGCACATGCGGAGACACACCGGGGAGAAGCCGTTCCGCTGCGCGCACTGCGGCCGCGCCTTCGCCGACTGCTCCAACCTCAACAAGCACCGCCGGCAAGTACACAAAGACTACAGCCTGCTGGCGCCGGCGCTGCAGGAGACGGCGGAAGTGATCACACAGGAAGCGGGAGTGATCACACAGGAAGCGGGAGTGATCACACAGGAAGCGGGAGTGATCACACCGGAAGCGGACGAGAGCATCATCTACGTCGCTTATGATGTCAGCGACCCCGCTTCCGCTTTCCGGATCTTAGAGCCGGACCAGAAAAAAGTAATGCAAAATAATAAAATTATTATGAAACGTCGTTATCGTACGATAATCAAATTACATGGTACGGGGGCGTCAGCTGTTTGGAACAAGAGATACCTAGGTAGCGCGCATGTACGAGGCATGCGGTCAGCACGTGTAGAGAGCGAGACAAATGCTGTATGCGCTATCTGTCTCGTCGCCGGCGCGCGACGCGCGTCCGGCGTGCGGTCTATCAAACGAGGGAGATCCCCCGCGCACAAAGGTCAACCGCCTAGCGCCTGTATAAAGTATCCCTACACACTAGTCGGTCACTACACATGA
Protein Sequence
MEVSLYNSSVCRLCGEENDNGTLLFTCEENNQSLSEMINGYLPLKVSDDGALPRTICPGCTIQLEATVEFLDLIIKGQKVIRRLYLREKEYRKNLVHPQEQQEINLETEKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNSHINPENGVYQAEHPVSLQAAGLDKPKRKRGRPPKPKPTPHDIEKEVEIQREIIEKEKVNEEPSGKRRRRTPNRYKEAVQGKELEKIFLEEGVIDDDDVDKESSQSEPGKGRGRPKGRTRPTHEQCAICGMNFTCVGRYMSHVAAHGPVSFRCECGFRSDTRLQLNEHQRVRGHRGHTATTPGVRTHRGHTATTPGVRTHRGHTATTPGVRTHRGHTATTPGVRTHRGHTATTPGVRTHGGTPPPPRRGYVHTGCPPPHGGYVHHTTPGVRTHRGHTATTPGVRTHRVHTATTPGVRTHRGHTATTPGVRTHRGHTATTPGVRTHRGHTATTPGKVPAKEQPKPEPVVEAEPELPSVEKIVDNVLMTEMPDMPGMPDMPGMPDLTDPLKDDSTDPLGLTPKMENEAPLEAPTESEDKPAAPEKRRLKCNHCDKTFSNKQSKSLHIKAVHLGVRPYACAECGARFAYPRSLALHALSHRRRRLKQGYACDLCGKVRLPALTRTARAVAPPPPPQAGLRVRPVRQGTSTRAHSHCTRCRTAAAASSRATRATCAARYVYPRSLALHALSHRRRRLKQGYACDLCGKVRLPALTRTARAVAPPPPPQAGLRVRPVRQGTSTRAHSHCTRCRTAAAASSRATRATCAARYVYPRSLALHALSHRRRRLKQGYACDLCGKVRLPALTRTARAVAPPPPPQAGLRVRPVRQGTSTRAHSHCTRCRTAAAASSRATRATCAARYVYPRSLALHALSHRRRRLKQGYACDLCGKVRLPALTRTARAVAPPPPPQAGLRVRPVRQGTSTRAHSHCTRCRTAAAASSRATRATCAARYVYPRSLALHALSHRRRRLKQGYACDLCGKVRLPALTRTARAVAPPPPPQAGLRVRPVRQGTSTRAHSHCTRCRTAAAASSRATRATCAARYVYPRSLALHALSHRRRRLKQGYACDLCGKVLNHPSSVAYHKVAEHAGQRYVCNKCGKHFKHKQLLQKHQLVHSHSRPYHCQECSASFKTKANLINHQMLHSGVKRFSCEICKQKFAHKTSLTLHMRWHTGLKPYQCKVCDKRFSQKGNLSEHERIHSGDKPYKCGVCAWRFTTSSQHRLHVRRHDRAAPPSAPSAPPAPARPKAVRRARSFVCGVCARACGDRWALSKHMRRHTGEKPFRCAHCGRAFADCSNLNKHRRVSHTHTHTHRWALSKHMRRHTGEKPFRCAHCGRAFADCSNLNKHRRVSHTHTHTHPLGAQQAHAETHRGEAVPLRALRPRLRRLLQPQQAPPGQSHTHTHTHTHTAGRSASTCGDTPGRSRSAARTAAAPSPTAPTSTSTAGSVTHTHTHTPLGAQQAHAETHRGEAVPLRALRPRLRRLLQPQQAPPGQSHTHTHTHRWTLSKHMRRHTGEKPFRCAHCGRAFADCSNLNKHRRVSHTHTHTHAGRSASTCGDTPGRSRSAARTAAAPSPTAPTSTSTAGSVTHTHTHTAGRSASTCGDTPGRSRSAARTAAAPSPTAPTSTSTAGSVTHTHTHTAGRSASTCGDTPGRSRSAARTAAAPSPTAPTSTSTAGSVTHTHTHTAGRSASTCGDTPGRSRSAARTAAAPSPTAPTSTSTAGSVTHTHTHTAGRSASTCGDTPGRSRSAARTAAAPSPTAPTSTSTAGSVTHTHTHAGRSASTCGDTGEKPFRCAHCGRAFADCSNLNKHRRVSHTHTHTPLGAQQAHAETHRGEAVPLRALRPRLRRLLQPQQAPPGQSHTHTHTRWALSKHMRRHTGEKPFRCAHCGRAFADCSNLNKHRRVSHTHTHTPQGAQQAHAETHRGEAVPLRALRPRLRRLLQPQHAGSVTHTHTHTLSKHMRRGRSRSAARSKHMRRHTGEKPFRCAHCGRAFADCSNLNKHRRVSHTHTHTHRRALSKHMRRHTGEKPFRCAHCGRAFADCSNLNKHRRQVHKDYSLLAPALQETAEVITQEAGVITQEAGVITQEAGVITPEADESIIYVAYDVSDPASAFRILEPDQKKVMQNNKIIMKRRYRTIIKLHGTGASAVWNKRYLGSAHVRGMRSARVESETNAVCAICLVAGARRASGVRSIKRGRSPAHKGQPPSACIKYPYTLVGHYT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-