Cnig014024.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cantharis nigra
Gene Symbol
zfh1
Assembly
GCA_958510845.1
Location
OY294030.1:5309589-5319081[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.021 1.1 10.7 1.0 2 23 52 74 51 74 0.95
2 9 0.0013 0.069 14.5 0.5 3 23 106 126 104 126 0.95
3 9 1.8e-05 0.00092 20.4 0.6 2 23 133 154 132 154 0.97
4 9 3.6e-05 0.0019 19.4 5.8 1 23 163 185 163 185 0.99
5 9 0.00014 0.0072 17.5 1.0 1 21 191 211 191 212 0.95
6 9 0.84 44 5.6 5.3 2 19 456 473 455 475 0.93
7 9 2.2e-05 0.0011 20.1 0.9 1 23 822 844 822 844 0.94
8 9 0.00033 0.017 16.4 9.4 1 23 850 872 850 872 0.98
9 9 0.0052 0.27 12.6 4.3 1 21 878 898 878 899 0.96

Sequence Information

Coding Sequence
ATGGTGGCGCGTAGTGAAAGCATGTATGGGTGCTTCGACAGCTACTCCTACAGACTCTGGAGCCTTGCCAATGTATGGAACACCTGTCAATTTCCGCCATTGATAAACGGTTTAAATAAAGAAGTGGAAGAATTGAATCCCGAATGCTACATAAAATGCCCCCAATGCCAGAAAGGTTTGCCGACTTTCCAAAGCCTAAAAGAACACATCGAAAGTTGTCATCCTGAATTAACAGCGACTGAGAATGGCAGCGTGGCAACTCCTAGTGCAATATCTCCTACACCCAGCATCGTAGGACCTGGAGGATCTTACGGCTGTTCGCAGTGTGCTACGTCGTTCACAAGCAAGGATCAACTGGAAAAACACGAACTTTTACATTCGCCAAATGCTCAAGTGTCCtgcaaaatttgcaacaaaaccTTTGCTAATGTCTACAGACTACAACGACACATGATCAGCCACGACGAAAGTGCCGTcttaagaaaattcaaatgcaCAGAATGCGAAAAAGCGTTCAAATTCAAACATCACCTGAAGGAACACGTACGAATTCACAGTGGAGAGAAACCATTCGAGTGTGGAAACTGTGGAAAAAGATTTTCTCATTCCGGTTCCTACTCTAGTCACATGACATCGAAGAAGTGTTTGGTCATGAATCTTAAACTGGGCAGAGCGCGTGGATCGCCCGGAAACTCCCTTTTAGACAAAGCGGCGTCTCAAAACGGCCGCGGGCCAAAAAGAATCTCGTCAAATCCCTTAAACAATAATCTCGCCACTAGTCCAAATCATAACGCTTATTTGCCAATCCTTCCTAAATACACAGAAGCCGCGGCTGCCTTTTTGCATAACTCGCTCGCTTCGAATCACGGCATCCATCCGTTTTACATGACCCCCTCTAACATGCTCCATAGTTCTAATTCATCCCTTAGTCCATATTCGCTTCCCTCATTAAATCACATCCTAGAACAATTACAAGGAGTCTCACCGCACCGTTCGCAATATCATCACGAAGCATCAGAGGACAACTTCATCCCCGAAGACAGAATAAAACAGGAACCCTCTTCTTACTCCCCAAAACCACACGAACCGCAATCCAACTTCGAAAAATCAAACTCTTCCAGTTGTGGCGACTTGGTGATGGCCACCGAAATGGAAAACAACGATTCCGTCAGAAAAGCCGAGAACCGATCCGTTGACGCTAACAGCAATGGTGACGATTTGGAAACCGTCAAAAAAATGATCGAAACCGTCAACGCGACCGTCACCAAACAATTACTCCAAGCAAACATTCTCAAACATCAAGACGACGATGTGAGCGAAAGCGATCGTCCCGAATCCCGCGACAGTAACATACAAGTTGATCTCACCTGTTCGAATTGCAAGCAACACTTTTCAAACCAACACTCGCTGGACGATCACAATTGTGACCGAACCGAAAAAAGTGAAGGTCTCGCCGCGAAATTAGAAGAGTCCGTTTTTAAAGGCGACGAATCTCACAATAACGACTACAGCTGCGGCGAGGACGATATGGACTCGGATCGGGTTCACGACAAAGGGGAAGATTACGAATTGGATTGCGAATCCGTCACCACCACAGATCAAGTTTCGGAAGATGGAAGAAAAGTTCGCGTGCGTTCCTTAATTGCAGATAAACAGTTGAAAGTGTTAAAAGACTACTACCTAGTTAATCCCAGACCAAAACGAGAGGAGTTAATGAAAATTGCCGAGAAAATTGGTTTTCAAGTGCGCGTAGTGCAGGTTTGGTTTCAAAATACCCGCGCTCGAGATCGAAGAGAAGGAAGATTGATTCAAGTTCCGTACAGTCCAGTCGCGTCAGTTCCTCTTAGAATGTCTTCAAGTATGGTGTCTTCTGGCTCGCAATCTTTGGGTCCTAGAACCGCCTACCCGCTAGATCCGTCTCCTCATTATATGTCCGAACAACCTTTAGACTTGTCGATAAAGAAGAGTCCCATGTCTGGTCACTCATCTCCGGCCGCTTCTCCACACAGACCCCCTTCTTCTAACTTACAATCCGATTCCGGCGAAGAGGTAGTCAACTTAAGCCACAAGTCGTCGCGAAGTCCTACGCCATTTCATTCTTCTTACCAAAATCATTACCAAAATTCCAATTCTTCGTCCGATCATCATCGATCACCTTCTCCAATGGACTTCAACAACGGAAGCAAATTGGCAAAAATTTTGGCTCAACCCACACATCCCCTTAACATGCCAATTGAAGGTTTCATGAGGCTTCCGGTTTTGAGTCAATTAATCACAAATCGAATTTCGAGTTTAAGTCCCACAATCGAAAAAAGAAAGTGGAGTGAAGATAGTGATTATATGATTTCTCAAGATGGGCTGCTGCAAGACGACTTAAATAAAAGACATAAAGTTTCACAGATGGTTATGAAGGGCCTAAATAGTCCTGGGCTGGGAAATCCAGATGGGGAAGTGGAAGGACAGTTTATTTGTGATCAATGTGATAAAGctttttcaaaacaaagttCCCTTGCTCGTCACAAGTATGAACATTCTGGACAACGCCCCCACAAGTGTGACGAATGCCCGAAAGCATTTAAACACAAACATCACTTAACAGAACACAAACGCCTTCACAGTGGTGAAAAACCGTTCCAGTGCAGCAAGTGCCTAAAACGCTTTTCACATTCGGGTTCTTACAGTCAGCACATGAATCATCGCTATTCCTATTGCAAACCTTACAGAGAATAA
Protein Sequence
MVARSESMYGCFDSYSYRLWSLANVWNTCQFPPLINGLNKEVEELNPECYIKCPQCQKGLPTFQSLKEHIESCHPELTATENGSVATPSAISPTPSIVGPGGSYGCSQCATSFTSKDQLEKHELLHSPNAQVSCKICNKTFANVYRLQRHMISHDESAVLRKFKCTECEKAFKFKHHLKEHVRIHSGEKPFECGNCGKRFSHSGSYSSHMTSKKCLVMNLKLGRARGSPGNSLLDKAASQNGRGPKRISSNPLNNNLATSPNHNAYLPILPKYTEAAAAFLHNSLASNHGIHPFYMTPSNMLHSSNSSLSPYSLPSLNHILEQLQGVSPHRSQYHHEASEDNFIPEDRIKQEPSSYSPKPHEPQSNFEKSNSSSCGDLVMATEMENNDSVRKAENRSVDANSNGDDLETVKKMIETVNATVTKQLLQANILKHQDDDVSESDRPESRDSNIQVDLTCSNCKQHFSNQHSLDDHNCDRTEKSEGLAAKLEESVFKGDESHNNDYSCGEDDMDSDRVHDKGEDYELDCESVTTTDQVSEDGRKVRVRSLIADKQLKVLKDYYLVNPRPKREELMKIAEKIGFQVRVVQVWFQNTRARDRREGRLIQVPYSPVASVPLRMSSSMVSSGSQSLGPRTAYPLDPSPHYMSEQPLDLSIKKSPMSGHSSPAASPHRPPSSNLQSDSGEEVVNLSHKSSRSPTPFHSSYQNHYQNSNSSSDHHRSPSPMDFNNGSKLAKILAQPTHPLNMPIEGFMRLPVLSQLITNRISSLSPTIEKRKWSEDSDYMISQDGLLQDDLNKRHKVSQMVMKGLNSPGLGNPDGEVEGQFICDQCDKAFSKQSSLARHKYEHSGQRPHKCDECPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00949709;
90% Identity
iTF_00268050;
80% Identity
iTF_00270961;