Basic Information

Gene Symbol
Zbtb41
Assembly
GCA_958510845.1
Location
OY294029.1:12734389-12735174[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 4.8e-06 0.00025 22.1 0.3 1 23 10 32 10 32 0.98
2 8 3.8e-07 2e-05 25.6 1.1 1 23 38 60 38 60 0.99
3 8 0.0012 0.062 14.6 2.3 2 23 65 86 64 86 0.97
4 8 0.0016 0.085 14.2 2.2 3 23 114 134 112 134 0.97
5 8 0.0013 0.067 14.5 7.1 1 23 140 163 140 163 0.96
6 8 3.2e-06 0.00017 22.7 1.0 1 23 171 193 171 193 0.98
7 8 3.1e-05 0.0016 19.6 3.2 1 23 199 221 199 221 0.99
8 8 0.029 1.5 10.2 0.3 1 20 227 246 227 248 0.94

Sequence Information

Coding Sequence
ATGCGAGTTCATACGGGAGATAAGCCATTCGTGTGCGAAATATGCAAAAATGCTTTCGCAACCAATAGTACGTTGAATACTCACATGGTAACTCattcaaaagaaaaacaatatgTGTGTGGTATTTGTGGTAAAAGCTATAGCCAAAAAATGACGCTAAAATATCACTTGAAGACACACTCCATCCAGTTAACTTGTCATATTTGTAACGGACATTTTTCCACTCGCAATGAATTGGCGTATCATGTAGAAACGCATTCGAagttgaatttaaaacaaaacgtAGAGGTTCCCAGCGTACTGGTTCCCGTAGCCCTCACCCAAGAAAACAAgctattttgcaaaatttgcagCAAGACATGTGCATCTCAACGTTTATTTGATGTACATCTGAGGATCCATACCGGAGAAAAACCGTTCAGGTGTTCCAAGTGCGATAAATTTTTTACACATTTCAGAAATTTAGAGTATCACAACAAAAGTTTtcattccaaaaaaaattcgtCAAGTTTTTCTTGCTCCATCTGCAACAAGACCTACAATGTTGAAAAAACTTTGAAGATTCACATGCGGATTCACACGggtgaaaatttgtataaatgtGATTTATGTTCGTACGTGTGTCCGACGAAATCCGCGTTTGAAAAGCACACAAGAACccatacgggggaaaaacccTTCGAGTGTAATGAATGCGAATTTAAAGCCGTGTCGAAGCAAGGCCTGAAACACCATATCACCATAGCTTCACcgaagaatttaataattgtaatatttgcgATATAA
Protein Sequence
MRVHTGDKPFVCEICKNAFATNSTLNTHMVTHSKEKQYVCGICGKSYSQKMTLKYHLKTHSIQLTCHICNGHFSTRNELAYHVETHSKLNLKQNVEVPSVLVPVALTQENKLFCKICSKTCASQRLFDVHLRIHTGEKPFRCSKCDKFFTHFRNLEYHNKSFHSKKNSSSFSCSICNKTYNVEKTLKIHMRIHTGENLYKCDLCSYVCPTKSAFEKHTRTHTGEKPFECNECEFKAVSKQGLKHHITIASPKNLIIVIFAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
-
80% Identity
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