Basic Information

Gene Symbol
-
Assembly
GCA_958510845.1
Location
OY294029.1:46412302-46414029[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.0017 0.086 14.2 1.2 1 23 105 127 105 127 0.98
2 16 0.0044 0.23 12.8 0.9 1 23 133 155 133 155 0.98
3 16 0.0058 0.3 12.4 0.4 1 23 163 185 163 185 0.97
4 16 0.00043 0.022 16.0 0.9 1 23 191 213 191 213 0.97
5 16 0.00029 0.015 16.5 1.0 1 23 219 241 219 241 0.97
6 16 0.0089 0.46 11.9 0.5 1 23 247 269 247 269 0.96
7 16 0.0025 0.13 13.6 1.5 1 23 275 297 275 297 0.97
8 16 9.3e-06 0.00049 21.2 1.5 1 23 303 325 303 325 0.97
9 16 0.0033 0.17 13.2 4.2 1 23 331 353 331 353 0.97
10 16 0.00015 0.0079 17.4 0.2 1 23 359 381 359 381 0.97
11 16 1.1 60 5.2 5.1 1 23 387 409 387 409 0.96
12 16 0.0023 0.12 13.7 2.5 1 23 415 437 415 437 0.97
13 16 0.002 0.11 13.9 0.6 1 23 458 481 458 481 0.97
14 16 0.0049 0.26 12.7 2.3 1 23 487 509 487 509 0.99
15 16 0.0011 0.058 14.7 2.2 1 23 515 538 515 538 0.97
16 16 0.00013 0.0067 17.6 4.0 2 23 546 567 545 567 0.96

Sequence Information

Coding Sequence
ATGACGTTTAATATCTCCACCATAACCTCAAACCAAAAAGACGATTTAACTGGATTGGAACCTCTGGAAGAATCAAACGTTACCATAACGAAGCAAGAACTATTTTTGGAAGAGTCTAAAACTACAGATTTGTTTCAAATCAGTAATATAAACAGTTTTTGTAAAATCGAAAAAGTCGAACCGGAGGATCTGGAATTGGATGTGAAAGATTTACATCATTCGGTTGAAATCAAAGACGAGAAATCTGTTCTGGAAACCCAACTGAAGGAAACACTCGATGTAAAAATATGCGCCGGGTCTCTGGCTAAACTATTTGAATGCGGTGTATGCGACTATAAGAGTATCAAGAGGAAAAACTTcacaaatcatttaaaaattcacagtGAAGACAAGTCATTCGAGTGTGAAGTTTGTAACTTTAAAACTGCGATTAAGGTTAGATTGAAGAGACATTTAAGAACTCACACGGACTATAGTCAGAAACCGTTCGCATGCGAAGAATGTGATTACCGAACGTTACGGGCACGAGATTTGAGAAATCATATCAACAAGCACACTGGTCAAAAACCGTTTGCTTGTCAATTTTGCGATTTTAGAACTGTGCGCAAGGATGGACTGAAAAAACATGTAAGGATACataccggtgagaaaccatttgcatgtgaaatttgtgattttaaatgtGTACGTTTATATGGATTGAGAGATCATATGAAAATTCATAGCGGTCTAAAACCATTTTCGTGTGATTCTTGTGACTTTCAAACTGCGCGAAAGGATGCGTTGAAGAAGCATTCAATAGTTCATtctggcgaaaaaccatttgcgTGTGATgcttgcgattttaaatgtgcACGCAAAGATGGTTTGAAGAAACATGTCAAGAtgcataccggcgagaaaccgcaCGTTTGTGAAATTTGTGGATATAaatttacactgaaaaaatatttgcaagtgCATTTGAGAGTTCATACGGATGATAAACCGTTTGTGTGCGAATTTTGTGGTTATAAATGTTTCCGTAAAGAAACACTGAAGGAACACTCGAGAATGCATACTGGCGATAAACCATTCGCTTGTGAAGTTTGCGATTTTAGGTCTGCACGGAAGGATGGCTTGAGAAAGCATATAAAAATCCATAGTGGGGAGAAACCTTTCGTTTGCGAATGCTGTGGTTATAAATGTTTTCTCCAGAGAACTTTGAAGGATCATTTGAGAGTTCATACTGGCGAGACGCCATTCGCCTGTGAACTTTGTGATTTTAAATGTAAGTTGAAGCAAGGTTTAAAGCGACACATGAATATCCATATCGGAGAACAGCTGTCGGTGTCGGAAGAGACTGGATTAATTCCTGTCGATCAGAAACCATTTTCGTGTGAAGTTTGCGACTATAAAAGTCCGGTTAAACAGAATCTAAACCAACACGTCAAGAGGAATCATTCCGGTAAGAAACCGTTTAAATGTAAagtttgtgactataaatgtatTTGGGAGTCGAAACTGACACAGCACATaagaattcataccggcgagaaaccgtatgcTTGTGCagtttgtgactataaatgttcgTTCAAGCCTAGTTTGAAAAAGCATATTATGAAAACTCACACCGCTAGCGAGAAAACTTGtgcttgtgaaatttgtgactacaATTGTACAACTTTGCAAGGTTTAAAGCGGCACATGAGAACTCACACCGTTTTAAAGTGCGAAACGCCATGA
Protein Sequence
MTFNISTITSNQKDDLTGLEPLEESNVTITKQELFLEESKTTDLFQISNINSFCKIEKVEPEDLELDVKDLHHSVEIKDEKSVLETQLKETLDVKICAGSLAKLFECGVCDYKSIKRKNFTNHLKIHSEDKSFECEVCNFKTAIKVRLKRHLRTHTDYSQKPFACEECDYRTLRARDLRNHINKHTGQKPFACQFCDFRTVRKDGLKKHVRIHTGEKPFACEICDFKCVRLYGLRDHMKIHSGLKPFSCDSCDFQTARKDALKKHSIVHSGEKPFACDACDFKCARKDGLKKHVKMHTGEKPHVCEICGYKFTLKKYLQVHLRVHTDDKPFVCEFCGYKCFRKETLKEHSRMHTGDKPFACEVCDFRSARKDGLRKHIKIHSGEKPFVCECCGYKCFLQRTLKDHLRVHTGETPFACELCDFKCKLKQGLKRHMNIHIGEQLSVSEETGLIPVDQKPFSCEVCDYKSPVKQNLNQHVKRNHSGKKPFKCKVCDYKCIWESKLTQHIRIHTGEKPYACAVCDYKCSFKPSLKKHIMKTHTASEKTCACEICDYNCTTLQGLKRHMRTHTVLKCETP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00268884;
90% Identity
iTF_00268884;
80% Identity
-