Basic Information

Insect: Cantharis nigra
Gene Symbol: zfh1
Assembly: GCA_958510845.1
Location: OY294028.1:88015879-88022303[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 1.8e-06 9.5e-05 23.5 2.7 1 23 117 139 117 139 0.99

2 20 0.00027 0.014 16.6 2.7 1 23 145 167 145 167 0.98

3 20 0.012 0.61 11.5 0.9 1 23 175 197 175 197 0.97

4 20 5.1e-05 0.0027 18.9 1.9 1 23 203 225 203 225 0.98

5 20 0.068 3.5 9.1 1.4 1 23 234 256 234 256 0.97

6 20 0.015 0.81 11.1 1.7 1 23 262 284 262 284 0.95

7 20 0.00077 0.04 15.2 0.1 1 22 290 311 290 311 0.96

8 20 1.6e-07 8.1e-06 26.8 0.8 1 23 318 340 318 340 0.98

9 20 0.00025 0.013 16.7 0.6 1 23 346 368 346 368 0.96

10 20 1.2e-06 6.1e-05 24.1 0.6 1 23 374 396 374 396 0.98

11 20 0.02 1.1 10.7 0.2 2 20 673 691 672 693 0.93

12 20 0.0022 0.11 13.8 0.6 2 23 701 722 700 722 0.96

13 20 1.7e-07 8.9e-06 26.7 0.5 1 23 728 750 728 750 0.98

14 20 6.3e-05 0.0033 18.6 0.1 1 23 756 778 756 778 0.99

15 20 2.8e-05 0.0014 19.7 0.7 1 23 784 806 784 806 0.97

16 20 2.5e-07 1.3e-05 26.2 3.6 1 23 812 835 812 835 0.97

17 20 7e-05 0.0037 18.5 0.6 1 20 841 860 841 863 0.92

18 20 0.0017 0.087 14.1 1.0 1 23 869 891 869 891 0.97

19 20 0.12 6.3 8.3 5.3 1 23 902 924 902 924 0.98

20 20 0.00041 0.021 16.1 1.2 1 23 928 951 928 951 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	1.8e-06	9.5e-05	23.5	2.7	1	23	117	139	117	139	0.99
2	20	0.00027	0.014	16.6	2.7	1	23	145	167	145	167	0.98
3	20	0.012	0.61	11.5	0.9	1	23	175	197	175	197	0.97
4	20	5.1e-05	0.0027	18.9	1.9	1	23	203	225	203	225	0.98
5	20	0.068	3.5	9.1	1.4	1	23	234	256	234	256	0.97
6	20	0.015	0.81	11.1	1.7	1	23	262	284	262	284	0.95
7	20	0.00077	0.04	15.2	0.1	1	22	290	311	290	311	0.96
8	20	1.6e-07	8.1e-06	26.8	0.8	1	23	318	340	318	340	0.98
9	20	0.00025	0.013	16.7	0.6	1	23	346	368	346	368	0.96
10	20	1.2e-06	6.1e-05	24.1	0.6	1	23	374	396	374	396	0.98
11	20	0.02	1.1	10.7	0.2	2	20	673	691	672	693	0.93
12	20	0.0022	0.11	13.8	0.6	2	23	701	722	700	722	0.96
13	20	1.7e-07	8.9e-06	26.7	0.5	1	23	728	750	728	750	0.98
14	20	6.3e-05	0.0033	18.6	0.1	1	23	756	778	756	778	0.99
15	20	2.8e-05	0.0014	19.7	0.7	1	23	784	806	784	806	0.97
16	20	2.5e-07	1.3e-05	26.2	3.6	1	23	812	835	812	835	0.97
17	20	7e-05	0.0037	18.5	0.6	1	20	841	860	841	863	0.92
18	20	0.0017	0.087	14.1	1.0	1	23	869	891	869	891	0.97
19	20	0.12	6.3	8.3	5.3	1	23	902	924	902	924	0.98
20	20	0.00041	0.021	16.1	1.2	1	23	928	951	928	951	0.94

Sequence Information

Coding Sequence: ATGTCTGTTCGTATGGTAGATTTTATACGACGAATGACTTCCATTAAGatGGTTAAAGGCGATGGTCTTCCAGAACATCTATGTTTAGGTTGTATCGAAACCATCTTTAAGGCTTTCAATTTCACCCAGGTGTGTATAAGTTCAGATTCTCGTTTGAGATTGCAGCTGACGGAAAATAAGCAATCGGAAGTGGTACAGAACGAAAGCAAATCGGAAAAAGACGAATTGGTGGAACTGTTGCATTGCAACGTGCTAGAAATTGTGCACGAACAAGatgaaaaaattgaagttaagaTTGAAAACATACCCAGCGAATATATTAAAGTTCAGAAATCTTACGATCAAGAATTCAAGTGCGAGGATTGTCACAAATCCTTTTCTGCTAAAGagaaacttgaaaagcatatgcAAGTGCACGATACCAATAACCAGCACAAGTGTTCCGAGTGTCTGAGGTCGTTCCCATTAAAAAAACAGTTGAGCGTTCACATGAGATCTCACGTTAAATTGGAAGATAAGCAATATGTCTGCGACGTTTGCGGACTGAGTTTTTTGTACTCTTATTTACTTAACcaacataaatttaaacattcaatCGATAAGCCATTTCCTTGTTTGAAATGCAATAGAGGTTGTGTAACGGCCGAGAGTTTACGTCGGCACATGAAAACTCACGAAGAGAATTACGAAAGAAAGAAGCACACTTGCACTGTGTgtttgaaagaatttttatacCCAAGTTTTTTAGCAGAGCACATGAAAAATCATACAGGTGAAAAGCCATTCTTATGTTCATTTTGTGGAAGGGGTTTTCGGCAACGTGGGGCACTGGATTGTCACATACGAAGTCATACCGGACTCAAGCCATACATTTGCCCAAATTGTAACGGTCGATTTTCTTCTaaagGAGTTTTGAAGATACACATGCGGCGTTACACCAACGAGAGGCCTTACGTATGTGATATTTGTGGGAAGGCTTTTGCCAGATCTTCCGATTTGAAGAGTCATCATAGATTGCATACTGGACGTAAGGAATTTTTGTGTACTGTTTGTGGAAAATACATGTCGAGCAAAGGTCAGTTGACGGTCCATTTGAGGACTCACACTGGAGAAAAACCTTTCAGTTGTGACATTTGCCAAAAAGCGTTCAGCACCCGCACGATGTTGGTGAAACACATAAGGATTCATACTGATATGtctaaactaaataatttaaaatcaaaatccagcATTAAAAACAGAATTCTCCACTTCAACAAAATTTGTCGATCTTGTTTAACCGAACGAGGTCACTTACGTGACATATTCTCAACACGTTTACCTTTAATGATTCAAAATTGCGCTGGAATCGAGGTTGTCGAAAATGATAAACTACCAAGCAAAATTTGCGTATCATGCTTCCATCAGATTGCCAAATTGTATACTTTCAAGAAGAAATTGGAACGAAACGATAAGATTTTGAGAAACAATTTGAAGTTGCAGAAGTCGAACAAAACTAAACAGTTTTCCGATATCTTACATAGAGCGGTTAACGACGCAGAAATTACATTAAATGACAATAAAAGTGTTAAGCTGGGATGCGAAGAAAGTGATTCGAGTGACGACGAGGATGTGCCTTTAAGCGAGAGGTTAAAAAATGGAGGAGCACAAAATTCGTCCCGATTGTTACGAAAAAGTAAGCAGAAGGCGAATAAAATTATTGACGATATAATTAGATCGGAGGAAGAATCGGAGGTTTCGGAAGGTTTTAGTGATGTCGAGAGTGGATCTTTTCACGAGGAATTCAAACCTGCCTTGAAGTGTTCTAATTTTGAATCGGTGTTTTACAACGACGAGCCACCACCATTGATACCTTTAGTGCCCACAAAATTGACAAATGCTGTTGACACTGCTCCGAAACTACTACCAGAAAATGCTCCTCCTTTGGTGCCAATTAAATCTCTCACGTCTTTAAATCCATCAGTGATTGTGAACGCTTTGGGTGACAACATTGAAAATTCTATGGAGTTAAAGTTACAGTGTAACGTTTGCAATGAAGAATTTAATTCggtatttgctttaaaaaatcaTCGCTTGAATTTTTGTCAAGCTTCTAATATGCAATGCAATATTTGTAAGAAAGAGTTTAACGATAGGACACGTCTGATTGGGCACCTAAAAGGTCACATGGTTTCGAAAGATTATGCATGCAAGATCTGTGGGAAACGTTATCCAAATCCTAGCACATTTCGTGTTCACATGCGAACGCACACCGGTGAAAGACCTTACAAATGTCAAGTTTGCAACAAGGGGTTTGTGCGTTGGGCAGGTGTAGTGGGGCACATGAAGACGCACAATTCTAATAAACCATACAAGTGTGAGACCTGCGGTAAAGGgtttaaaataacttcaaatttgGAACGGCACAAAATTTTACACTCCGGTATTCTGCCTTATTGTTGCAGCTACTGTGGTAAAACGTTTAGTCAATCTGACAATTTGCAACTTCATGTGCGAACATATCACACCAACGACAGGCCTTATTTGTGTAACGAGTGCGGCAAGAGGTTTGTAAGCTCGACGCGATTGAAAAGACACATGTGGGTGCACACTGGCTATAAGCCGTACATGTGTCGCTACTGTCCCAAAGCATATTCCAACTCTAACGACCGCAAGAATCACGAACGTGGTCACACGGGTGGAATTTCGGATTCGGACAAACCTTATGCTTGCAATTCGTGCGATATGAGGTTTTTGCATCCGTGCAGATTGACCAAACATATGAAAACACACGAAAGACCTTATCCGTGTAACGAGTGCACTAGAACTTTCAGTTCCGAGATTTTACTAAACAAACACAAGAGTAATAAACATGGGCCTCAATTTGTTGATCATTTGTCTATGCCATTAACTGTCGAAGAagtttacataaattattaa
Protein Sequence: MSVRMVDFIRRMTSIKMVKGDGLPEHLCLGCIETIFKAFNFTQVCISSDSRLRLQLTENKQSEVVQNESKSEKDELVELLHCNVLEIVHEQDEKIEVKIENIPSEYIKVQKSYDQEFKCEDCHKSFSAKEKLEKHMQVHDTNNQHKCSECLRSFPLKKQLSVHMRSHVKLEDKQYVCDVCGLSFLYSYLLNQHKFKHSIDKPFPCLKCNRGCVTAESLRRHMKTHEENYERKKHTCTVCLKEFLYPSFLAEHMKNHTGEKPFLCSFCGRGFRQRGALDCHIRSHTGLKPYICPNCNGRFSSKGVLKIHMRRYTNERPYVCDICGKAFARSSDLKSHHRLHTGRKEFLCTVCGKYMSSKGQLTVHLRTHTGEKPFSCDICQKAFSTRTMLVKHIRIHTDMSKLNNLKSKSSIKNRILHFNKICRSCLTERGHLRDIFSTRLPLMIQNCAGIEVVENDKLPSKICVSCFHQIAKLYTFKKKLERNDKILRNNLKLQKSNKTKQFSDILHRAVNDAEITLNDNKSVKLGCEESDSSDDEDVPLSERLKNGGAQNSSRLLRKSKQKANKIIDDIIRSEEESEVSEGFSDVESGSFHEEFKPALKCSNFESVFYNDEPPPLIPLVPTKLTNAVDTAPKLLPENAPPLVPIKSLTSLNPSVIVNALGDNIENSMELKLQCNVCNEEFNSVFALKNHRLNFCQASNMQCNICKKEFNDRTRLIGHLKGHMVSKDYACKICGKRYPNPSTFRVHMRTHTGERPYKCQVCNKGFVRWAGVVGHMKTHNSNKPYKCETCGKGFKITSNLERHKILHSGILPYCCSYCGKTFSQSDNLQLHVRTYHTNDRPYLCNECGKRFVSSTRLKRHMWVHTGYKPYMCRYCPKAYSNSNDRKNHERGHTGGISDSDKPYACNSCDMRFLHPCRLTKHMKTHERPYPCNECTRTFSSEILLNKHKSNKHGPQFVDHLSMPLTVEEVYINY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -