Basic Information

Insect: Cantharis lateralis
Gene Symbol: Zfy2
Assembly: GCA_963170105.1
Location: OY720626.1:3322058-3331325[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.00086 0.045 15.0 0.4 1 23 118 140 118 140 0.98

2 25 7.5 3.9e+02 2.6 1.8 1 23 145 167 145 167 0.89

3 25 0.00025 0.013 16.7 0.5 2 23 173 194 172 194 0.94

4 25 0.023 1.2 10.5 0.1 1 23 200 222 200 222 0.98

5 25 0.0034 0.18 13.1 0.2 2 23 234 255 233 255 0.95

6 25 0.0074 0.38 12.0 5.8 3 23 282 302 280 302 0.96

7 25 2e-06 0.00011 23.3 1.0 1 23 308 330 308 330 0.98

8 25 0.0056 0.29 12.4 3.4 1 23 336 359 336 359 0.97

9 25 0.48 25 6.4 1.2 3 23 371 392 369 392 0.95

10 25 5.9e-07 3e-05 25.0 0.3 1 23 467 489 467 489 0.98

11 25 0.00027 0.014 16.6 5.1 1 23 495 517 495 517 0.96

12 25 3.4 1.8e+02 3.7 0.4 1 17 523 539 523 540 0.92

13 25 0.61 32 6.0 3.7 5 23 623 641 620 641 0.95

14 25 0.00083 0.043 15.0 2.1 1 23 647 670 647 670 0.98

15 25 0.00028 0.015 16.5 1.1 1 23 676 698 676 698 0.95

16 25 0.14 7.3 8.0 6.2 1 23 704 726 704 726 0.96

17 25 6.9 3.6e+02 2.7 1.9 1 20 1036 1055 1036 1057 0.94

18 25 8.9e-05 0.0046 18.1 3.7 1 23 1091 1114 1091 1114 0.93

19 25 5.5e-05 0.0028 18.8 2.5 3 23 1125 1145 1124 1145 0.98

20 25 2.7e-05 0.0014 19.7 3.0 1 23 1151 1173 1151 1173 0.99

21 25 0.00013 0.0067 17.6 0.3 1 23 1181 1203 1181 1203 0.98

22 25 0.00034 0.018 16.3 4.4 1 23 1209 1231 1209 1231 0.99

23 25 4.4e-05 0.0023 19.1 4.0 1 23 1371 1393 1371 1393 0.98

24 25 0.0026 0.13 13.5 0.3 2 23 1397 1418 1396 1418 0.96

25 25 0.00013 0.0067 17.6 0.9 1 23 1424 1447 1424 1447 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.00086	0.045	15.0	0.4	1	23	118	140	118	140	0.98
2	25	7.5	3.9e+02	2.6	1.8	1	23	145	167	145	167	0.89
3	25	0.00025	0.013	16.7	0.5	2	23	173	194	172	194	0.94
4	25	0.023	1.2	10.5	0.1	1	23	200	222	200	222	0.98
5	25	0.0034	0.18	13.1	0.2	2	23	234	255	233	255	0.95
6	25	0.0074	0.38	12.0	5.8	3	23	282	302	280	302	0.96
7	25	2e-06	0.00011	23.3	1.0	1	23	308	330	308	330	0.98
8	25	0.0056	0.29	12.4	3.4	1	23	336	359	336	359	0.97
9	25	0.48	25	6.4	1.2	3	23	371	392	369	392	0.95
10	25	5.9e-07	3e-05	25.0	0.3	1	23	467	489	467	489	0.98
11	25	0.00027	0.014	16.6	5.1	1	23	495	517	495	517	0.96
12	25	3.4	1.8e+02	3.7	0.4	1	17	523	539	523	540	0.92
13	25	0.61	32	6.0	3.7	5	23	623	641	620	641	0.95
14	25	0.00083	0.043	15.0	2.1	1	23	647	670	647	670	0.98
15	25	0.00028	0.015	16.5	1.1	1	23	676	698	676	698	0.95
16	25	0.14	7.3	8.0	6.2	1	23	704	726	704	726	0.96
17	25	6.9	3.6e+02	2.7	1.9	1	20	1036	1055	1036	1057	0.94
18	25	8.9e-05	0.0046	18.1	3.7	1	23	1091	1114	1091	1114	0.93
19	25	5.5e-05	0.0028	18.8	2.5	3	23	1125	1145	1124	1145	0.98
20	25	2.7e-05	0.0014	19.7	3.0	1	23	1151	1173	1151	1173	0.99
21	25	0.00013	0.0067	17.6	0.3	1	23	1181	1203	1181	1203	0.98
22	25	0.00034	0.018	16.3	4.4	1	23	1209	1231	1209	1231	0.99
23	25	4.4e-05	0.0023	19.1	4.0	1	23	1371	1393	1371	1393	0.98
24	25	0.0026	0.13	13.5	0.3	2	23	1397	1418	1396	1418	0.96
25	25	0.00013	0.0067	17.6	0.9	1	23	1424	1447	1424	1447	0.97

Sequence Information

Coding Sequence: atgaaaacaattgaagAAGAGATTCAAACAAATGTTGCAGGCGAAATTTATACTTACATAGCGATACCGATTAACAGTCTTAAGCAGAGCAATGACATTATTCAAACTGTACAACCGTTGCAAATTGCTTCAAATGTGATTTACAACGTTTTACCTCACGATGGTAcaactgaaaaaattcaaacttataCTCTAACAGACCAGTTTATTGAAACTTTGAGAGAAAACGATAAGgAGCCCGATGTAATTGAAAATCAGGAAAGCTTAAGACCTACGGTGATAGAACAAATCAATAACACCCGGAAGTCAGTTATTTTGGaaacaagtttaaataaagATGAGGCATTGACTTACGAATGTTTGAGTTGCGGTGAAGTTTTTAAATCGCGTCCGGGTTATCGTAAACATCTAGAAAAACATAAAGAGAAACTTTACAAATGTGACGAGTGCTCGGCAAGTTAcaattgtgaaattaatttcaaattacacaAAGTTGTGCACACGAAGGATGCTACCGTCTGTCCAGTGTGTGAGAAGTCATTTAATCGAATGGCTAGTTTAAAAAACCATCTTACTTTTCACGAAATTGAAGAGACCTTTACTTGTACTGAATGTTGGGCAGCATTTGATGCCGAGGAAGAGTACAACAAGCACATCCAAAACCATAAAAGTGAAGCCCAGTCGCTGCAGATATTGTTGGTTTGTTCCGTTTGTGacgaaaaatttgaagatcgtGCCATGTACAAGCAACATATATTGTTTCATACAGAGGTTAAAAAATTGCTGAAGATAAGAAAAACGCCAAAAAAACGCAAAGCAGTGAAAAGAACTTCATCACATTTATGCGACGTGTGTAAAAAgacattttccaaatattgCTTGCTTATAAGACACAAGAGAATCCATACCGGTGAAAAACCATATGTTtGCCATTATTGCGACCGTGCCTTTGCACAAAAAGGAACATTGCGTattcacttaaaaattcacaCCGGATTGAAGCCATTCAAGTGCACAATTTGTATGGCTAAATTTAGTCAAAAGTGTAATCTTAGGGCTCACGTTCAAAGAACGCATCTGCATGAGAAAACctctgaaaaaatttatggttGCCAGCTTTGCGCATGTGCTTTCAAGAGAATTGCATCTTTAAACGCTCACACCACACGCTTTCACAGAGGCGATAAAGATAGTAATGATATTGTAGACCTCATGCAGCAAATCGATCAACTGGAAAAccaaatgaataataaaaccaaTCTTCCAATAAACGATATCCTTAAAAGAAACGTAATTGAAAACGATTCGGAAAAATTTGTAAGACTGGCCGATTCGAGTGTTGAAGGGCCTATACAATATTTTCTagtaaaacagaaaaaaactaCCGAAGGACTGTGGTATGCATGCTCTTATTGCGAGAAGGAGTTTAAAAAACCTTCAGATTTAATTCGTCATATTCGAATCCACACCATGCAAAAACCTTTCAAAtgtaaACACTGTAATCGGCGGTTTTCGTTAAAATCAACTCTCAAAAATCACGTAGTCAGTCATGCTAATTTTCGGAGTTATGAATGTATTATTTGCAAGGCGACGTTCAATTctaagaaaagtttaaaaaataactccAAgattgatgataaatttatatgtGGTTCTTGTAAACCAGCGGCTTctgattttaaagttaaacgCGTTgttaatgttgaaaaattagaagctctaAAGGTTCTTAATAATCTAAATATCGACATTGAATTAAAGCAACCAATGGTGGAGAGTTCTGAGGGTTTGGTACCCATTATTTCACCCAAAGCAAAGATTCATTCAGACAGTGCTAACTCGAATAGACCTAAGCTGCATAGGTGTCACTGTGGAGCCGAGTTCTTTCAACTTAAGAAACTACAGAACCACATGTTAATTCATACCAgcgaaaagaaatttaagtgttACGTTTGCACCAAAGGTTTCCACAACTCTCAAGCATTAAAAGAACATATAAAATCGGTTCATAACGGTGAAAGAAAGTTTTTATGCAGAATATGTGACAAACGTTTTGTTACgaacacaattttaaaaaggcaCATGATCACGCACAGTTTTGTCAAACCTTACATTTGCCCGTATTGCAAAAAGCGCTTCAAAACGATTCTGCATTGTCGTCAACACATCAAACTTCACAAGAAGGATATCTTGTTAAATGCATTAACAGCAAATGAGTCGAACAAATTTACTAATAGTTTTGTGGCAGAAGCAGCTCTTCCCGAAAATTTGTTTGCTAATACGTTACCCGATGGTTCTTATAATTtaggtttaaattttgataatttaacaGACTCTGCTGGTATATCTGGTGCTTCTAATCTTTTGTCTGAAACTTCTGAATCAGTGGAACAAAATAAAGGTGAGACTCAAATTTTGTACACGGATAAAGGTAACGGAGTAATTGTTTCCACACCTTTGGATATTTCTCAGACACACgaTGGAAAAATTAAGTTGGAGCAACAGCTGCTTTTAACATCGACTGCTTTACCAAGTTATGACGAAtcgacaaaaaatattagcacagataatttagaaaatgttgATGATACCATTGCTACTTTACCACAAGAAAATTCGacggttttcttaaattttgatgacCTACATTTAGCAACTTCTAACCTCTACAGCTCCTACCCAAATTTAAAGaaTTTTGATCAACTGTTGGGAGAAATAAGTGAAATACAagataataacattttattgacCAGTGATTCCAGTCTAAGTCAGCTGACCGATTCTCAATTGGacacttcaaattttgatggaTTAATGCCATTTGCATTCAATACCAACATATCTTTGAATAACGTCACTCTATCCACTACAAATCCTTTCCCAAATGGCATTCTTTCAAACGTTAGTGAAGACGTTCCAGACCTCAACCAAGTGCCACTTCCAGATCTGCCTTACGACGTCAAAAAAAGTTCTGGAGTAGAAGAATCTCAAAAAATGTTAGAAGAAAAGGaagaaaaaccaattttatcTAATCTTCTTGAAACTTCTTCCAGTGGTGAGCCCATAATCTCAAACACAGacgaaacaatttttgaaaacgttgATTTTACCTGCTCTTCTTGTAAGAAATATCTGGATAATGTGGAAGATTTGGTGCATCATTACTGTGCTGGAAAAGTTGCTGCAGAAGGAATTGCCAAAGAAAGTCAAAATGATGGTTTACCAAGCTACGAAGATTCTATTCAAGCAAAAAAGAAGATTAAAAATGGTCATAAATGTAAGAAATGCAACAAAACTTTCACTACTAAACTCAGCTTGCAAAAGCATGTGGTGGTACTTCATCGAGAGAAAAAAAATGCAGCCTCAAATATTTGTTCCTATTGCGAAAAGGGTTTTAAAAAGCACTCGGATTTGCTGAGACACGTTAGGACTCACACAGGAGAGAAGCCCTTCACTTGCGATATGTGCCAAAAGAATTTTACACTCAAATCCACTTTGGAAACTCATCGAAGAACTCACAATCCAGAATCACATCAAAAATATGATTGTGGTGTTTGTGGCACTCATGTCAGCTCGAAAGCTAGTCTACGAGTTCACATGATGATGCATACTGGTGCCAAACCTTACCAGTGTTCGgtgtgttttgaaaattttagaacgtCCGGTCACAGAAGATCTCACATGAGAACTcatctaaataataataaagcgAGAAAGCAATCAAAATCGACAAAAGTAACCACCATGCTGCAATCTGTTATCACGGAAACTCAAAACAGTGAAGAACTTTATGAGGAGGTTTTACTATTAAACAACTCACAACACttagaagaaaataaagaactCATTTTGCAAGACTCGGAGGTTCTCTTTCCCAATCAAACAGTTCAAGTGGATTCTTTGATTTTGCAGCAGTTACAACAAAGCTGTGTTTTGCTAGAAGATGGAAACGACAGAATTCCACCTTTTATTCAGGTTGATTTTAACAACTATGGTGAAATAACGAACGTCAAGTCTATTCGAGACATTCAGGAATCGTTCAAAACCACCGAGCCAGATAAAAACAccgaaaatatttacttaacgAAGAAGGCATCCCCTGAGCGGAATTTTGAGTGTGATATTTGCCATAAAAAGTACACCACTAAATCTGTACTCACAAAACATAAAAGAATACACAATAAGTTGAATTGTGCAAAgtgtaacattaaatttatgcaatCTGAAGAACTTCAGGAacacttaaaaatacataatgtaATTCGACCCTTTGCTTGCTCTCTCTGTGACAATAGTTTTAGCctcaagaaaaatttaattacccaTATGAAAAGaATACATAGCGCTAGTTTTCCGTGA
Protein Sequence: MKTIEEEIQTNVAGEIYTYIAIPINSLKQSNDIIQTVQPLQIASNVIYNVLPHDGTTEKIQTYTLTDQFIETLRENDKEPDVIENQESLRPTVIEQINNTRKSVILETSLNKDEALTYECLSCGEVFKSRPGYRKHLEKHKEKLYKCDECSASYNCEINFKLHKVVHTKDATVCPVCEKSFNRMASLKNHLTFHEIEETFTCTECWAAFDAEEEYNKHIQNHKSEAQSLQILLVCSVCDEKFEDRAMYKQHILFHTEVKKLLKIRKTPKKRKAVKRTSSHLCDVCKKTFSKYCLLIRHKRIHTGEKPYVCHYCDRAFAQKGTLRIHLKIHTGLKPFKCTICMAKFSQKCNLRAHVQRTHLHEKTSEKIYGCQLCACAFKRIASLNAHTTRFHRGDKDSNDIVDLMQQIDQLENQMNNKTNLPINDILKRNVIENDSEKFVRLADSSVEGPIQYFLVKQKKTTEGLWYACSYCEKEFKKPSDLIRHIRIHTMQKPFKCKHCNRRFSLKSTLKNHVVSHANFRSYECIICKATFNSKKSLKNNSKIDDKFICGSCKPAASDFKVKRVVNVEKLEALKVLNNLNIDIELKQPMVESSEGLVPIISPKAKIHSDSANSNRPKLHRCHCGAEFFQLKKLQNHMLIHTSEKKFKCYVCTKGFHNSQALKEHIKSVHNGERKFLCRICDKRFVTNTILKRHMITHSFVKPYICPYCKKRFKTILHCRQHIKLHKKDILLNALTANESNKFTNSFVAEAALPENLFANTLPDGSYNLGLNFDNLTDSAGISGASNLLSETSESVEQNKGETQILYTDKGNGVIVSTPLDISQTHDGKIKLEQQLLLTSTALPSYDESTKNISTDNLENVDDTIATLPQENSTVFLNFDDLHLATSNLYSSYPNLKNFDQLLGEISEIQDNNILLTSDSSLSQLTDSQLDTSNFDGLMPFAFNTNISLNNVTLSTTNPFPNGILSNVSEDVPDLNQVPLPDLPYDVKKSSGVEESQKMLEEKEEKPILSNLLETSSSGEPIISNTDETIFENVDFTCSSCKKYLDNVEDLVHHYCAGKVAAEGIAKESQNDGLPSYEDSIQAKKKIKNGHKCKKCNKTFTTKLSLQKHVVVLHREKKNAASNICSYCEKGFKKHSDLLRHVRTHTGEKPFTCDMCQKNFTLKSTLETHRRTHNPESHQKYDCGVCGTHVSSKASLRVHMMMHTGAKPYQCSVCFENFRTSGHRRSHMRTHLNNNKARKQSKSTKVTTMLQSVITETQNSEELYEEVLLLNNSQHLEENKELILQDSEVLFPNQTVQVDSLILQQLQQSCVLLEDGNDRIPPFIQVDFNNYGEITNVKSIRDIQESFKTTEPDKNTENIYLTKKASPERNFECDICHKKYTTKSVLTKHKRIHNKLNCAKCNIKFMQSEELQEHLKIHNVIRPFACSLCDNSFSLKKNLITHMKRIHSASFP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00927943;
90% Identity: iTF_00271523;
80% Identity: -