Basic Information

Insect: Cantharis lateralis
Gene Symbol: ZFX
Assembly: GCA_963170105.1
Location: OY720628.1:36188712-36196558[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 37 5.4e-05 0.0028 18.8 0.3 1 23 52 74 52 74 0.98

2 37 5e-07 2.6e-05 25.2 1.6 1 23 80 102 80 102 0.98

3 37 3.9e-05 0.002 19.2 0.7 3 23 110 130 108 130 0.98

4 37 0.00011 0.0055 17.9 2.4 2 23 137 158 136 158 0.97

5 37 5.6e-05 0.0029 18.7 0.7 1 23 164 186 164 186 0.98

6 37 0.00066 0.034 15.3 3.7 1 23 192 214 192 214 0.98

7 37 0.12 6.1 8.3 2.9 1 23 220 242 220 242 0.98

8 37 0.004 0.21 12.9 0.6 1 23 248 271 248 271 0.97

9 37 0.00089 0.046 14.9 0.7 1 23 277 299 277 299 0.97

10 37 0.0001 0.0054 17.9 2.3 1 23 305 327 305 327 0.97

11 37 0.0028 0.15 13.4 1.5 1 23 333 355 333 355 0.99

12 37 0.00037 0.019 16.2 2.8 1 23 361 383 361 383 0.96

13 37 0.00013 0.0069 17.5 0.3 1 23 389 411 389 411 0.99

14 37 0.0045 0.24 12.7 1.7 3 23 419 440 419 440 0.94

15 37 0.16 8.3 7.8 0.7 1 23 446 468 446 468 0.97

16 37 0.018 0.93 10.8 2.0 2 23 475 497 474 497 0.91

17 37 0.0024 0.13 13.6 1.8 1 23 503 525 503 525 0.98

18 37 0.039 2 9.8 4.0 2 23 532 554 531 554 0.93

19 37 0.00059 0.03 15.5 0.2 1 23 560 582 560 582 0.98

20 37 0.0001 0.0054 17.9 2.3 1 23 662 684 662 684 0.98

21 37 0.1 5.3 8.5 4.0 1 23 690 713 690 713 0.94

22 37 0.027 1.4 10.3 0.9 1 23 719 742 719 742 0.97

23 37 6.5e-06 0.00034 21.7 4.0 1 23 747 769 747 769 0.98

24 37 0.0019 0.098 13.9 0.6 1 23 775 797 775 797 0.97

25 37 7.3e-05 0.0038 18.4 1.6 1 23 809 831 809 831 0.98

26 37 1.1e-05 0.00059 20.9 2.4 1 23 837 859 837 859 0.97

27 37 0.0048 0.25 12.7 2.1 1 23 865 887 865 887 0.98

28 37 0.00051 0.027 15.7 1.5 1 23 893 915 893 915 0.95

29 37 1.1 55 5.3 5.3 1 22 921 942 921 944 0.88

30 37 0.00011 0.0055 17.9 1.3 1 23 950 972 950 972 0.97

31 37 0.16 8.2 7.9 1.6 1 19 978 996 978 1001 0.90

32 37 0.0084 0.44 11.9 7.6 1 23 1007 1029 1007 1029 0.98

33 37 0.0002 0.01 17.0 3.7 1 23 1035 1057 1035 1057 0.98

34 37 0.0079 0.41 12.0 5.1 1 23 1063 1085 1063 1085 0.98

35 37 0.032 1.7 10.0 1.0 1 23 1091 1114 1091 1114 0.90

36 37 5e-07 2.6e-05 25.2 1.5 1 23 1120 1142 1120 1142 0.98

37 37 0.00017 0.0086 17.2 5.2 1 23 1148 1170 1148 1170 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	37	5.4e-05	0.0028	18.8	0.3	1	23	52	74	52	74	0.98
2	37	5e-07	2.6e-05	25.2	1.6	1	23	80	102	80	102	0.98
3	37	3.9e-05	0.002	19.2	0.7	3	23	110	130	108	130	0.98
4	37	0.00011	0.0055	17.9	2.4	2	23	137	158	136	158	0.97
5	37	5.6e-05	0.0029	18.7	0.7	1	23	164	186	164	186	0.98
6	37	0.00066	0.034	15.3	3.7	1	23	192	214	192	214	0.98
7	37	0.12	6.1	8.3	2.9	1	23	220	242	220	242	0.98
8	37	0.004	0.21	12.9	0.6	1	23	248	271	248	271	0.97
9	37	0.00089	0.046	14.9	0.7	1	23	277	299	277	299	0.97
10	37	0.0001	0.0054	17.9	2.3	1	23	305	327	305	327	0.97
11	37	0.0028	0.15	13.4	1.5	1	23	333	355	333	355	0.99
12	37	0.00037	0.019	16.2	2.8	1	23	361	383	361	383	0.96
13	37	0.00013	0.0069	17.5	0.3	1	23	389	411	389	411	0.99
14	37	0.0045	0.24	12.7	1.7	3	23	419	440	419	440	0.94
15	37	0.16	8.3	7.8	0.7	1	23	446	468	446	468	0.97
16	37	0.018	0.93	10.8	2.0	2	23	475	497	474	497	0.91
17	37	0.0024	0.13	13.6	1.8	1	23	503	525	503	525	0.98
18	37	0.039	2	9.8	4.0	2	23	532	554	531	554	0.93
19	37	0.00059	0.03	15.5	0.2	1	23	560	582	560	582	0.98
20	37	0.0001	0.0054	17.9	2.3	1	23	662	684	662	684	0.98
21	37	0.1	5.3	8.5	4.0	1	23	690	713	690	713	0.94
22	37	0.027	1.4	10.3	0.9	1	23	719	742	719	742	0.97
23	37	6.5e-06	0.00034	21.7	4.0	1	23	747	769	747	769	0.98
24	37	0.0019	0.098	13.9	0.6	1	23	775	797	775	797	0.97
25	37	7.3e-05	0.0038	18.4	1.6	1	23	809	831	809	831	0.98
26	37	1.1e-05	0.00059	20.9	2.4	1	23	837	859	837	859	0.97
27	37	0.0048	0.25	12.7	2.1	1	23	865	887	865	887	0.98
28	37	0.00051	0.027	15.7	1.5	1	23	893	915	893	915	0.95
29	37	1.1	55	5.3	5.3	1	22	921	942	921	944	0.88
30	37	0.00011	0.0055	17.9	1.3	1	23	950	972	950	972	0.97
31	37	0.16	8.2	7.9	1.6	1	19	978	996	978	1001	0.90
32	37	0.0084	0.44	11.9	7.6	1	23	1007	1029	1007	1029	0.98
33	37	0.0002	0.01	17.0	3.7	1	23	1035	1057	1035	1057	0.98
34	37	0.0079	0.41	12.0	5.1	1	23	1063	1085	1063	1085	0.98
35	37	0.032	1.7	10.0	1.0	1	23	1091	1114	1091	1114	0.90
36	37	5e-07	2.6e-05	25.2	1.5	1	23	1120	1142	1120	1142	0.98
37	37	0.00017	0.0086	17.2	5.2	1	23	1148	1170	1148	1170	0.98

Sequence Information

Coding Sequence: atggtATTTTCGCAAGCAGTAGAAAATGGCAGCACTGACATTAAAACCGAAGAAATGCAGGATCCGGATGTCGAGTTGGAAAGTTTACATCACTCCATCGAGATTAAAGACGATGACTTGGAAGAAGACTGCGAACCACGAATTAGTAGACAATTCGAATGCGGGGTATGTAATACCAAGTTTCCCACTAATTGGCAGCTTACACGGCATGCAAAAATTCATATCTCCACCCATGAGTTTGAGTGTACGATCTGTGATAAAACATTTTCGTTTCGAGACTCCTTGACGAAGCACTTAAAGGTACACACCGGTGAAAAACCGTTCGGTTGTGAAGTATGCGGTTTTAAAAGTTCTCGGAAGGAAAATCTCAAAGCTCACTTACGGACTCATACCGGTGAAAGACCGGTTGAGTGTAAAATATGCGACTTCAAATGTTCGAAACCTTCAACTTTAAAAAGACACATGGTAACCCACACTGGGGAGAAACAGTTCACCTGCGCAATTTGTGATTTGCAATTCACGCGTTTATCAACCTTGAAAAGTCATTTGAATCTGCATACTGGTGAGAAACCATTTTCGTGCTCAATTTGCGATTTTAAGTGTTCCCAAAGGGCAAATTTGAACACCCATTTATTTACCCATAATGGTAAGAAACGGTTTAAGTGTGacatttgcaaattttcatgtttatttttatcggGTTTGAAAAGTCACTTACGAATTCATAGTGGAGAAAAACCTTTTAAGTGCAATGTTTGCGATTTTAAGTGTGCGGCCTCGACAGGTTTAAAACGGCATATCATCGTCGCCCATACTGACACAAAGCCATTTACATGTAATGTGTGCGATTATAAAGCTTACACAAAAAGTGCGTTGAAAAGTCATTTAGGAACTCATACAGGCGAAAAGCCATTTGCCTGCGCAGTTTGTGGTTACAAAACATCGCGTAAACATTCATTGAAACTTCATTTACGAACGCACACTGGCGAGAAGCAGTTTAAATGTGAAGTGTGCGATTATAAAACCCATCAAGAGGGAAGCTTGAAAATTCACGTACAAACTCAcaccggcgagaaaccatttgagTGCAAAATTTGCGGTTTTAAATGCACACGGTCGGCGAGTTTAAAATATCACATGGTAAATCACACTGGTGAGAAACCGTATGTATGtgaaatttgcgattataaaaccTCGATCAAGGCAAGTTTGAGAATTCATCTACGTACTCATACAGGCGAGAAACCGCTCGGGTGTAAAATTTGCGACTTCAAATGTGCACAATCGTCAAGTTTGAAAAACCATATTATTGCAACTCACACTGACGAGAAACCATTTATATGTGAAGTATGCGGTTATCAAACGGCTCTAAAGGGAAGTTTGAAATGCCACCTACGAATCCATTCGGGGGAAAAACCGGTTCAGTGCAAAACTTGCGACTTTAAGTGTGCAAATTCTGGAAATTTGAGAAATCACAACATGGCAACTCATTCTGGCAAGAAACCCTTTTCATGTCAGCTGTGCGAATATAAAACTTCTTTAAAGGGAAGTTTGAAAACTCATCTGCGAACTCATACGGGTGAGAAACCGCTCGAATGTTCAATTTGCGGTTTTAAATGCGCGCATTCGGCCAGTTTAAAACATCATAACATGGTAAATCATGTTGAGGAGAAACCGTTCGTATGTGCAGTGTGTGGATATAAAACCACTTTAAAgggaagtttaaaaattcacctaCGAATTCATACGGATATGGATATGGACGGGGTGTTACCCCTCGAAGGGTtccaaattaaagaaaactttGATGAAGATTTTAAGACTGCGATTGTAAGTaacagtttcaaaattaaaatcgaagaGTTGGAAGACGTGAAATTTAATGTCGACGATCTGCATCATTCCATTGACATTAAAGAAGAGTGCAATGTTAAGCAATTACCACAGATAAATCCCGAAAggaaatttaacatattaaattcATTCGAATGTGCAATCTGCGGATGTAAAATTACACGGAAGGAATCGTTGAAACGGCATTTAAAAACCCACACCGGAGAGAAACCGTTTGCTTGCGAATTATGTGACTATAAATCTGCTCGTAagtgtcatttaaaaattcattacttAAACAGTCACACGGACGACAAACCCTTTTCGTGCTTAATTTGTGACTACGCAACTGCACACGAACCAAGTTTACGGGtgcattttaaaacttaccaCGGTGAGAAATCTTTTGTATGCAAAATTTGTGGCCATAAATTTGCGAAGAACTCCAACTTGACCAGGCATTTTAAAACGCACACCGGTGAGAAACCATTCGCATGTGAAATTTGCGACTACCGATCGGCACAGAAGATACACTTACAATCGCATGCACTAACGCACACTGAGAATCTGTTACGAAACATCGAGAAACAGTTTTCCTGCGAAGTTTGCGGTTACAAATGTGCCCAGAAATccgttttaaataaacatctcAGGATCCACACCGGAGAGAAACCATTTGCCTGTGAATTATGCGACCATAAATTCGcgcgaaattcaaatttgaaaatgcacTTGAAAACCCAcaccggggaaaaaccgttttcCTGCGATCTCTGTGACTATAAAAGTGCGCACAAACCAACTTTAAGACTTCATTTGAAAACTCACACCGGCGAAAAATCGTTTCCCTGCATAATATGTGACTGTAAGTTTGCCACGAAAGCCACCTtgaaaaatcatataaaaactCACACCGGGGAAAAACCATTTGCTTGCGAATtgtgcgattataaatgtgccCACAAAACCAGTTTAAAATATCACAACATTCACATTCACGCTGGCGAGACACCGTTTGCTTGTGAAATATGCGACTACAAGTGTGCTCAAAAATCCACCTTACAAAATCATGTAAAAATTCACAccggcgaaaaaccatttgcTTGTGAAATTTGCGACTACAAATCTGCTCATAAATCAAGTTTACTGTATCATAACGTACACGCTCACGCCGGCGAGACTCCGTTCTCTTGTGATATGTGTGACTATAAATGTGTACGTAAGTACAGATTAAAACATCACTTGAAAACTCACACCGGCGAGAAATCTTTCTGTTGCGAAATCTGCGATTACAAATACGCGCACAAAGCGAGTTtacaaattcatttaaaaacccACACCGGGGAGAAGCCGTTCTCTTGTGAATtttgtgactataaatgtGCTCTAAAATCCACCTTGAAAAATCATCGGAAAACTCACACCGGAGAGAAACCCTACCCCTGTAAACtctgcgattataaatgtgcgTACAAAGAAGGTTTAAAAGTTCACAATATTAACGCTCACACCGGTCAAAAACCGTTTTCGTGTGAAATATGCGACCGAAAATTCGCccgaaaaacaaatttaaaagtccaTTTAAAGACTCATTCAGACGAGAAGCCCTTTTCCTGtgaaatttgcgattataagtCTGCACACAAATCGCAtttgaaaaaccatttaaaaacTCACACCGACAAGGCTACgcacaaaagtttaaaacccGAAGATCCTAAATAA
Protein Sequence: MVFSQAVENGSTDIKTEEMQDPDVELESLHHSIEIKDDDLEEDCEPRISRQFECGVCNTKFPTNWQLTRHAKIHISTHEFECTICDKTFSFRDSLTKHLKVHTGEKPFGCEVCGFKSSRKENLKAHLRTHTGERPVECKICDFKCSKPSTLKRHMVTHTGEKQFTCAICDLQFTRLSTLKSHLNLHTGEKPFSCSICDFKCSQRANLNTHLFTHNGKKRFKCDICKFSCLFLSGLKSHLRIHSGEKPFKCNVCDFKCAASTGLKRHIIVAHTDTKPFTCNVCDYKAYTKSALKSHLGTHTGEKPFACAVCGYKTSRKHSLKLHLRTHTGEKQFKCEVCDYKTHQEGSLKIHVQTHTGEKPFECKICGFKCTRSASLKYHMVNHTGEKPYVCEICDYKTSIKASLRIHLRTHTGEKPLGCKICDFKCAQSSSLKNHIIATHTDEKPFICEVCGYQTALKGSLKCHLRIHSGEKPVQCKTCDFKCANSGNLRNHNMATHSGKKPFSCQLCEYKTSLKGSLKTHLRTHTGEKPLECSICGFKCAHSASLKHHNMVNHVEEKPFVCAVCGYKTTLKGSLKIHLRIHTDMDMDGVLPLEGFQIKENFDEDFKTAIVSNSFKIKIEELEDVKFNVDDLHHSIDIKEECNVKQLPQINPERKFNILNSFECAICGCKITRKESLKRHLKTHTGEKPFACELCDYKSARKCHLKIHYLNSHTDDKPFSCLICDYATAHEPSLRVHFKTYHGEKSFVCKICGHKFAKNSNLTRHFKTHTGEKPFACEICDYRSAQKIHLQSHALTHTENLLRNIEKQFSCEVCGYKCAQKSVLNKHLRIHTGEKPFACELCDHKFARNSNLKMHLKTHTGEKPFSCDLCDYKSAHKPTLRLHLKTHTGEKSFPCIICDCKFATKATLKNHIKTHTGEKPFACELCDYKCAHKTSLKYHNIHIHAGETPFACEICDYKCAQKSTLQNHVKIHTGEKPFACEICDYKSAHKSSLLYHNVHAHAGETPFSCDMCDYKCVRKYRLKHHLKTHTGEKSFCCEICDYKYAHKASLQIHLKTHTGEKPFSCEFCDYKCALKSTLKNHRKTHTGEKPYPCKLCDYKCAYKEGLKVHNINAHTGQKPFSCEICDRKFARKTNLKVHLKTHSDEKPFSCEICDYKSAHKSHLKNHLKTHTDKATHKSLKPEDPK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -