Basic Information

Gene Symbol
-
Assembly
GCA_949152465.1
Location
OX424437.1:39128569-39129378[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 2.9e-05 0.0019 19.7 0.8 2 23 18 39 17 39 0.97
2 9 0.00023 0.015 16.9 2.0 3 23 47 67 45 67 0.95
3 9 0.001 0.065 14.8 1.2 1 23 73 95 73 95 0.98
4 9 8.5e-05 0.0054 18.2 2.8 1 23 101 123 101 123 0.98
5 9 4.8e-06 0.00031 22.1 1.0 1 23 129 151 129 151 0.97
6 9 2.2e-06 0.00014 23.2 3.7 1 23 157 179 157 179 0.99
7 9 0.00019 0.012 17.1 7.1 1 23 185 207 185 207 0.97
8 9 0.0015 0.095 14.3 4.9 1 23 213 235 213 235 0.97
9 9 3.2e-06 0.0002 22.7 1.5 1 23 241 263 241 263 0.98

Sequence Information

Coding Sequence
ATGAAAATGGAAGATATAGAATCAGTGAATACAAATTCAGAAAGTTTAATTTCTTGCGATATTTGTTCGGTGAACTTTACAAAGAGATCCAGTTTGTTGAGGCATTTAAGAAACCATACAGGTGAAAAACCGCACTTATGTAATATTTGTTCAAAAAGATTTTCTTTGATGGAGAAGTTACGTATTCACATGAGAGCCCATACAGGTGAGAGACCATTTGTCTGCGAAGTTTGTGATTCTAGATTTGCGgtgaaatcaattttaaaacatcatttaaaaactcacacTCGTGAAAAACCGTTTTCTTGTGAAGTTTGCAGTATGAAATTTTCGCACAAGGGAAGTTTACGAAGTCATACACTATCTCATACTGGTGAGAAGTTACATGTGTGCCAAGTTTGTGACTTGCGGTTTGCGCGTAGTACGGAGTTGAGATCCCACTTAAGAATCCacacgggggaaaaaccgtatacATGTAATGTTTGCCATTTGAAATTTTCACAACAAGGAAGTATGACACgtcatttaagaactcacacCGGTGAAAAACTACACTCATGCACTCACTGCGACTATAGAACCTCTGAGAAAGGACATTTGCGTACTCACATGAGAGTCCATACCGGAGAAAAACCTTTTGAGTGTCAAGTTTGCAGTGCAAAATTTTCCCATAAATCTAACTTGCGTTGTCATTTAAGAGGACATacaggcgagaaaccatttgtGTGCGAAATTTGTAATATGAAATATACCCAAAATAGGAGTTTACAAAACCATTTAAAAACTCACGTGAAGATAGAAGATGATTAA
Protein Sequence
MKMEDIESVNTNSESLISCDICSVNFTKRSSLLRHLRNHTGEKPHLCNICSKRFSLMEKLRIHMRAHTGERPFVCEVCDSRFAVKSILKHHLKTHTREKPFSCEVCSMKFSHKGSLRSHTLSHTGEKLHVCQVCDLRFARSTELRSHLRIHTGEKPYTCNVCHLKFSQQGSMTRHLRTHTGEKLHSCTHCDYRTSEKGHLRTHMRVHTGEKPFECQVCSAKFSHKSNLRCHLRGHTGEKPFVCEICNMKYTQNRSLQNHLKTHVKIEDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00271673;
90% Identity
iTF_00271673;
80% Identity
-