Basic Information

Insect: Camptogramma bilineatum
Gene Symbol: topi
Assembly: GCA_958496255.1
Location: OY292470.1:5173986-5182777[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.013 0.91 10.8 1.8 2 23 73 94 72 94 0.96

2 12 0.015 1 10.6 0.4 3 23 102 123 100 123 0.93

3 12 0.21 14 7.0 0.1 2 23 131 153 130 153 0.88

4 12 0.01 0.7 11.1 4.9 1 23 159 181 159 181 0.96

5 12 1.9e-07 1.3e-05 26.0 2.3 1 23 187 209 187 209 0.97

6 12 0.0031 0.21 12.8 0.3 1 19 215 233 215 236 0.94

7 12 0.082 5.6 8.3 1.6 3 19 256 272 255 277 0.92

8 12 0.00011 0.0076 17.3 2.2 1 23 561 583 561 583 0.98

9 12 2.5e-05 0.0017 19.4 6.3 1 23 590 613 590 613 0.98

10 12 0.0019 0.13 13.4 1.4 1 23 621 644 621 644 0.96

11 12 7.3e-06 0.0005 21.0 2.3 1 23 650 674 650 674 0.98

12 12 8.2e-06 0.00056 20.9 0.5 1 21 680 700 680 701 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.013	0.91	10.8	1.8	2	23	73	94	72	94	0.96
2	12	0.015	1	10.6	0.4	3	23	102	123	100	123	0.93
3	12	0.21	14	7.0	0.1	2	23	131	153	130	153	0.88
4	12	0.01	0.7	11.1	4.9	1	23	159	181	159	181	0.96
5	12	1.9e-07	1.3e-05	26.0	2.3	1	23	187	209	187	209	0.97
6	12	0.0031	0.21	12.8	0.3	1	19	215	233	215	236	0.94
7	12	0.082	5.6	8.3	1.6	3	19	256	272	255	277	0.92
8	12	0.00011	0.0076	17.3	2.2	1	23	561	583	561	583	0.98
9	12	2.5e-05	0.0017	19.4	6.3	1	23	590	613	590	613	0.98
10	12	0.0019	0.13	13.4	1.4	1	23	621	644	621	644	0.96
11	12	7.3e-06	0.0005	21.0	2.3	1	23	650	674	650	674	0.98
12	12	8.2e-06	0.00056	20.9	0.5	1	21	680	700	680	701	0.95

Sequence Information

Coding Sequence: ATGGATTCGAATTTATCATATTTCAGTTTACCCTTTGTGGATACTGCCGACCTAGATTTTAGTAAAATCAGAGGTCAGGAGTGCGAGTACGATGACCTGCACCCTACTCTACCGTCCCACGGGTCCCTACTCGGCGCGGATGACGATGTTTTGGCACAATTTCTTTCTGGTGATGATCCCTTGGAAGAGCCCGACTTGAACGGACCCACTACATTGCACTGCGAGATATGTAGAAAGCAGTTTGATAATGCGAAGAAGTACTATGGGCATTTGCGGGTGCATTCAAAGGACAATCTTTGGATTTGTGATCAATGTCCCGATGAGAAGTTCTCAACTAAGCAGCAGCTGATGAAGCACAGCCTGACGCACCAGCCCCTGGAGCGAGTGTGGCGCTGCCCTCAGTGCGAGATGTCTTTTGAGGCGCTGTGGAGACTGCAGCAGCATTTGTTCGCTAAGCACTTGGATTATAGACCACACAAATGTGACTTGTGCTCAAAAACATTCCACAAACTATCAGATTTGGATAAACACAAAGATGTTCATGAAGAGCGCAAGAAACATCCATGCAGTGTGTGCAAAAAGAAGTTTGTAGATAAATCTAACCTGAAGCGACACATGCTGGTCCATAGCACTGAGAAACCATACGCTTGTTCTGGATGTGGGCATCGATTCACACAGaTAGCCTCAATGAGAAGGCACAGCCTAAACTGCCCCATGGCTCAGAAGAACCCGAGCGAGCCCAAGAAATCGTACCGCAACAACTATTGTAGGGTGTGTGGTCTCACGTTTCAATACAAGAGCTCTTTGCTGGAACATTGCGTCAGAGAGCACTCAAACAACCCTTCACAGCCACCTCCAGAAACTCCTAAGGAAGACAAATCTAACCAACTCCACGTCGACACAAACAGAACAGTCGACAAAATAGTTGACGATATCCTctcagccgaagacgattacatgACGATGTCAACACAAAACGAACTCATAAACTACCCAACCGAGGAAAACCAGGACAACTTAATGCAAATAGAATTGTTAAAAGAAATGAATCAGATTCACAACATGCATATATTAGACGATGAATTATTATACAGTGATATTGACTTAGACAGTTTTCAAACTATGTGTAACAATATAGATTATGAACGGAATGAATTATTTGATCTGAACGATGGTAGAGATATCATGAACGGTAGGAGTCTCGATCAGGATATAATGAATGCAATCGTGCGAGGAATTGATCAGGCCAAAGACGAAATACCCAAAGAGTTTGATCAACCAGAAATGAACAAAGTCAACGAGTATCTAGTAAACCCACCAGTTACTGTGAACGAATGTGCAACTATATTCGAAAGTGACGTCGATTTAGAAGCTAGTACCAATTTAGCAGCGAATTTAAATCAGCTTATTGGCGAAAATACTGTGCAGTATATTGCTACGGAAAACGATGATACGTTTATTATAAGTTTGAACAGCGAAATCGATGCTGAACAGTTAACAGATATGTTAAATATAGGAgttgataataaaacatttcaGAAGCCGTTGAAAAATGATTCTTGTTCTGATAGTAATGAATCTAAAATTGAAGCGGCGCCAACTGAGTCTGATCAAATTAAAGTTGAAAAGGAAGATAGTAAGGAAgaaaaatcaaagaaaaaagGTAGAACAAAGATAATGTACGTGTGTATGGTATGCAAGAagattttcaaaacgaaaaataacTACACATCCCATCGAGGTACACACGATTCGGATCTCAAGCAGTTTCAATGCAAAGTGTGCCACGAGCGATTCAGCTACCGCTCCACACTCAACAAACACACTAGAAAGCGTCACACGCCTATTGTGAAGAAAGCCCATACTTGTGATCTGTGTGATAAGAACTATAATGAAGCATGGCAGTTGAGACAGCACACAGAACGCAACCACAAATTGATTCAGCCATATCAATGTAATGAAAAGGATTGTGGGAAAAAGTTTTACCAAAAATTCGATTTGGAGAATCATttaagATTCCACACAGGAGAGACTCCGTACGTCTGTGACATCTGCAGCCGAGGCTTCAAAACATCGTCACATCTCGCGAGGCACGTCAAAAACGTTGATTGCACTAaacagtaa
Protein Sequence: MDSNLSYFSLPFVDTADLDFSKIRGQECEYDDLHPTLPSHGSLLGADDDVLAQFLSGDDPLEEPDLNGPTTLHCEICRKQFDNAKKYYGHLRVHSKDNLWICDQCPDEKFSTKQQLMKHSLTHQPLERVWRCPQCEMSFEALWRLQQHLFAKHLDYRPHKCDLCSKTFHKLSDLDKHKDVHEERKKHPCSVCKKKFVDKSNLKRHMLVHSTEKPYACSGCGHRFTQIASMRRHSLNCPMAQKNPSEPKKSYRNNYCRVCGLTFQYKSSLLEHCVREHSNNPSQPPPETPKEDKSNQLHVDTNRTVDKIVDDILSAEDDYMTMSTQNELINYPTEENQDNLMQIELLKEMNQIHNMHILDDELLYSDIDLDSFQTMCNNIDYERNELFDLNDGRDIMNGRSLDQDIMNAIVRGIDQAKDEIPKEFDQPEMNKVNEYLVNPPVTVNECATIFESDVDLEASTNLAANLNQLIGENTVQYIATENDDTFIISLNSEIDAEQLTDMLNIGVDNKTFQKPLKNDSCSDSNESKIEAAPTESDQIKVEKEDSKEEKSKKKGRTKIMYVCMVCKKIFKTKNNYTSHRGTHDSDLKQFQCKVCHERFSYRSTLNKHTRKRHTPIVKKAHTCDLCDKNYNEAWQLRQHTERNHKLIQPYQCNEKDCGKKFYQKFDLENHLRFHTGETPYVCDICSRGFKTSSHLARHVKNVDCTKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01528574;
90% Identity: iTF_01529447; iTF_00662484; iTF_00661600; iTF_01528574;
80% Identity: -