Cvom004981.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Calliphora vomitoria
Gene Symbol
-
Assembly
GCA_942486075.2
Location
CALNXM020000107.1:590866-592390[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 1.5 73 4.3 0.3 2 23 32 54 31 54 0.88
2 10 3.4e-05 0.0017 18.9 1.9 1 23 190 213 190 213 0.96
3 10 0.0015 0.074 13.8 0.2 3 23 233 254 232 254 0.91
4 10 0.018 0.9 10.3 9.3 1 20 257 276 257 279 0.94
5 10 7.7e-06 0.00038 21.0 2.5 1 23 285 309 285 309 0.97
6 10 0.0028 0.13 12.9 1.9 1 23 315 339 315 339 0.95
7 10 0.00042 0.02 15.5 0.6 2 23 346 367 345 367 0.96
8 10 1.2e-05 0.00058 20.4 0.0 1 23 373 395 373 395 0.97
9 10 0.0048 0.23 12.2 3.1 1 23 401 423 401 423 0.91
10 10 8.9e-06 0.00043 20.8 0.2 1 23 429 451 429 451 0.99

Sequence Information

Coding Sequence
ATGTTAAAAATTCTGCCCTTAGCCAATCTAAGCAATCAGCCGAAAGCAAAATGTGGCGAAATCTTTTGTCACAGCTCCAGTGACTTCACCATCTACTGCACCTTCTGTGACATGAAAGCCTTTACGTTCGAGGATTTCCTGTTGCACATACAAAATGTTCACTTCGAAAATAATATTTTAAAAACGGAAACCTTCACCAACGAGTGTAATCAGTATTTTGAGGTGAATGTTAAGGCAGAAGCCACAACAGACACCCTGGCTGGTGAGCAGTTGCATGAAGAGGAAGTGTTGTGGGATAATTTGGAACAAACATATGATGAGGCAGATGATCTGGGGCATGATGACTATGAGGAGGATGATGTTAACGACAGCTTTGAGGAGGAAACAGTGACGGTATTAAAGAAAACTAAAAAACAAATAAGAGCGAAAAAAGAAAAACGCGTGAAACCGAAGAGTGATATTGAAAGTGGAGATGATGAGGACAACGATCATAGTTCAGATGAGGATTTCAAACCCCTGTTAAATGATAAAGTATCCTCCACTGGTGGCCCGGAGGAGGACAAACCCTTTCAATGTACAGAATGCAGCAAAGCCTTTAAAAACCTGGGTCTTTTGAAAATACATCACACCCGCATTCACGAGGAAAAATCCGCCGAAAGTTTAGAGAAAAAAGAAAAGGAAGACAAGGAACAATTATGTCCGGAATGCGATCAAATATTTCCGAACAAAAAATATCTGGATAAACATGTTTTCGAGGATCATGGTGGTTACAAATGTGCACATTGTGATAAGCGTTTTAAACAGCGGCATCAACGCAAGCGCCATGAACAATGTCACACCGCAGAAAGAGTATTTACCTGCCATTTTGAAGGTTGCGGCAAAAGTTTCACCGAGAAATACTATCTCAAGCGCCACGTTGACATACACACCACGGAACGCAATTTCATTTGTGATTTTGAGAATTGCGGCAAAGCCTTTCATACCCAACGACGTCTGTCGGCCCATAAGAAAATTCATACGAAACCGAAAAATTTGGTCTGCGATGCGTGCGGCTACACCTGCCGCGAGAATGAAACGCTGCGTGTGCACCAACGTGTGCACACCGGCGAAAAACCCTATGCCTGCGAGGTATGCGATAAACGTTTCATATCCAGTTCTGCCTTAGGCGAGCACATGGCCTCTCATTCCAATACCCGTCCTCATGTCTGTAAAGTTTGCAATGCCTCGTTTGCCCGGCAAAAAGCCCTTTACCATCATAGTTTTCTGCACTCAGACGTTAAGAAATTTCGTTGTAAAATATGTGGCAGTGCCTACAAGCAGGCTTCCGGTTTGGCCGGTCACATGCGTAAACATCGTGAAGAGGGCATGATGTCTATGTTGCCCGAACGACCCACAATTTCAACGGCTCCCATACCGCCACCCAATGTTGTTGGCATGCCACCTTCGTATCCTTTTATGTCATTTTAG
Protein Sequence
MLKILPLANLSNQPKAKCGEIFCHSSSDFTIYCTFCDMKAFTFEDFLLHIQNVHFENNILKTETFTNECNQYFEVNVKAEATTDTLAGEQLHEEEVLWDNLEQTYDEADDLGHDDYEEDDVNDSFEEETVTVLKKTKKQIRAKKEKRVKPKSDIESGDDEDNDHSSDEDFKPLLNDKVSSTGGPEEDKPFQCTECSKAFKNLGLLKIHHTRIHEEKSAESLEKKEKEDKEQLCPECDQIFPNKKYLDKHVFEDHGGYKCAHCDKRFKQRHQRKRHEQCHTAERVFTCHFEGCGKSFTEKYYLKRHVDIHTTERNFICDFENCGKAFHTQRRLSAHKKIHTKPKNLVCDACGYTCRENETLRVHQRVHTGEKPYACEVCDKRFISSSALGEHMASHSNTRPHVCKVCNASFARQKALYHHSFLHSDVKKFRCKICGSAYKQASGLAGHMRKHREEGMMSMLPERPTISTAPIPPPNVVGMPPSYPFMSF