Basic Information

Insect: Calliphora vicina
Gene Symbol: topi
Assembly: GCA_958450345.1
Location: OY288232.1:147525423-147528379[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 8.9 7.7e+02 1.8 0.7 2 20 191 208 190 210 0.90

2 10 6.4e-05 0.0055 18.0 2.6 1 23 295 317 295 317 0.97

3 10 0.025 2.1 9.9 0.4 2 23 350 371 349 371 0.96

4 10 0.011 0.93 11.0 0.1 2 19 437 454 436 456 0.95

5 10 0.43 38 6.0 1.9 1 22 505 526 505 529 0.90

6 10 7.9e-07 6.9e-05 24.0 1.9 1 23 586 608 586 608 0.95

7 10 0.0047 0.41 12.2 1.1 1 23 614 639 614 639 0.95

8 10 0.69 60 5.3 1.7 1 23 645 667 645 667 0.88

9 10 1e-06 8.8e-05 23.7 0.3 1 23 673 695 673 695 0.98

10 10 0.031 2.7 9.6 3.3 3 23 703 724 701 724 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	8.9	7.7e+02	1.8	0.7	2	20	191	208	190	210	0.90
2	10	6.4e-05	0.0055	18.0	2.6	1	23	295	317	295	317	0.97
3	10	0.025	2.1	9.9	0.4	2	23	350	371	349	371	0.96
4	10	0.011	0.93	11.0	0.1	2	19	437	454	436	456	0.95
5	10	0.43	38	6.0	1.9	1	22	505	526	505	529	0.90
6	10	7.9e-07	6.9e-05	24.0	1.9	1	23	586	608	586	608	0.95
7	10	0.0047	0.41	12.2	1.1	1	23	614	639	614	639	0.95
8	10	0.69	60	5.3	1.7	1	23	645	667	645	667	0.88
9	10	1e-06	8.8e-05	23.7	0.3	1	23	673	695	673	695	0.98
10	10	0.031	2.7	9.6	3.3	3	23	703	724	701	724	0.96

Sequence Information

Coding Sequence: atgAATTTGAACGAAGAAGATTTTAATACTTCTGATTCTTGGCTATCGGAGCAATTATTTGCCCAGTTAAAGGATCTAAACTCTGAATATAAAGATAGAAACACTTCAACTGACTTTTTGCTAAATGATACTTTCCAGAATTGCGGTAGTAGCATACCATTATTGGATGTTTATGATGACATTCCTTTACAGGATTTAAAGCCAACTTCTTTGGATTCTTTTGAAACTGCACTGAATGTAAATACTTTCCCAGGTTCTTATAATATAAACGAGGAAGTTTTGGATTTGAGTCAAATGCCTTTAAAAGAACATCGCACAAAATCAGCTCAAACTGAAGGAAACTTGATTGATTTAGTAGAAAACATTCCTTTGGCAGTTGACCCTGTTGCAAGTAATGTAGAAACATTTATACATGATGCTTCTAATTTTGATCCACCTCCATTTGATGCTAACGAAGAggtactaaaaatattaaagtttttagaAACTCAACCAAAAGAAGAAATGGtttcagAGATTACTGTTCCTCAGCCATTAATATTGCCGTTATCGGGAgcaccaaaaataataaaatgtgtgaactgcaattttatatttaatatagaCGATTTTCAATCCCACGTTTGTGATTGTGATGATTATAATTTGATAaagccaaaagaaacaaaaattaatagcaCTTGTAAACCTATTAAGGAAGAAATTTCATTGCCACTAGAGCCAGCATGCATACGTTtactaaaagaaaatcaaatacgTATTAGACGCTTTCTTAAAGACGAATTAAAATATGATGTAAATACAACTTCCTCGTCTGGTGTTATAAATTCATCCATCACATCTAATGCTTCAATAACTAGTAATAAGAAACCAGATGGTCCTCACGAATGTACCTTATGTGAAAGAAAATTTGTGCATGCTTCGGGTTTATTACGTCATATGGAGAAGCATGCTTTGGATTTAATACCCAATGCTCATACAACAACTAATAATAAGAATGTAGCTACACAAGGGGCCCAAGGTATAAATGGCTTACGCGTAGTCATTAAATGCACCTTATGTGGTCGCATTTTCTTTGAATCGTATGAAGCTTTGAAGCATTTGTTTTCACATTTTCCGGACTCCATAGCTGAAGAAAAGGAAGTGGATAATTGTGCTGAAATACCTTACGATGCCTATATAGATGATGCCTTGAATAATCTAAATTCAGAGgcCCAAGGAATTTCATTTTACAATTCTCCTATTTCAAGCTATGAAGACGATAAAGCACCAGTTTACCTTAAAATAGTAATATTAAGTTGCATTTTGCAATGTGAATTTTGTGATCTAGTATTCTCTGATGTGTCCTATTTATTTGTACACTCAGCATGTCATTTACCATTTAGAAGATTTGAGTGTTTTGCTTGTGATATACATGTTAGAACATCGAAAGAAATCTGTACTCATTGGCATGCTGAATGTGTTTTTATGCGCGAAAATTTAAAAGTTCATCATGCAACTACTCaacgttattttgtttgtaatgtGTGTGAGAATAAGTTCCAATCCATGGATTTACTGCATGAGCATCGTTATACCTCTTATCATTTCTTTCCACGCCTGAACAAAAATACTGGTACTCTGCAATTGCCTTGTGAATATTGtgaatgtatttttgaaaacgCTCAAGAATGTGTTATCCACTATGAAGAGAAACATTACAGAAAGTACAAAAGAGATAAGGATGGTACTAAAGGGTCAAGTAAGACCCGACAATACTTGTGTGATATATGTGGAAAATCTTATACCCAATCTAGTCATTTGTGGCAACATTTGAGATTTCATCAGGGTGTGAAACCATTTGCATGTAAAGAACCAGGTTGTACTCGAAAATTTACAATTCGTCCCGACTTAAATGATCATATTCGCAAGTGTCACACCGGTGAAAGACCTTACCATTGTCTGGTATGTGGTAAGCGTTTTCTTACGGGGTCCGTTTTTTACCAACATCGTCTAATACACCGTGGCGAAAGACGGTATGAATGCGATGCTTGTGGGAAACGGTTTTATCGTGCTGACGCATTAAAAAATCACCAACGTATTCATACTGGAGAAAAACCATTTGGCTGTCACTTTTGCACCAAAAACTTCAGACAACGTGGAGATCGTGACAAACATATACGAGCTCGACACTCGCATCTGGATGCCAATGCTCGTCTCATGATGCAAATGCAAAAATTACAGTTAGAAGCTGCCGCAGCTCAAGAGCAGGACTCGCAAAAACTGGCCACTACATCACATTCTAAGGATGATATGTCTACAACTAATGAAAATATGCTACCGCCAGAATATAACACTGCACAGGTTTCCTATGTTAGgaataacaatttaaatgatATACTTATGATGGGCAatgtaaatttttccaaaaatgtttttgagtCTATAATGGGCGATATTATTCATTAA
Protein Sequence: MNLNEEDFNTSDSWLSEQLFAQLKDLNSEYKDRNTSTDFLLNDTFQNCGSSIPLLDVYDDIPLQDLKPTSLDSFETALNVNTFPGSYNINEEVLDLSQMPLKEHRTKSAQTEGNLIDLVENIPLAVDPVASNVETFIHDASNFDPPPFDANEEVLKILKFLETQPKEEMVSEITVPQPLILPLSGAPKIIKCVNCNFIFNIDDFQSHVCDCDDYNLIKPKETKINSTCKPIKEEISLPLEPACIRLLKENQIRIRRFLKDELKYDVNTTSSSGVINSSITSNASITSNKKPDGPHECTLCERKFVHASGLLRHMEKHALDLIPNAHTTTNNKNVATQGAQGINGLRVVIKCTLCGRIFFESYEALKHLFSHFPDSIAEEKEVDNCAEIPYDAYIDDALNNLNSEAQGISFYNSPISSYEDDKAPVYLKIVILSCILQCEFCDLVFSDVSYLFVHSACHLPFRRFECFACDIHVRTSKEICTHWHAECVFMRENLKVHHATTQRYFVCNVCENKFQSMDLLHEHRYTSYHFFPRLNKNTGTLQLPCEYCECIFENAQECVIHYEEKHYRKYKRDKDGTKGSSKTRQYLCDICGKSYTQSSHLWQHLRFHQGVKPFACKEPGCTRKFTIRPDLNDHIRKCHTGERPYHCLVCGKRFLTGSVFYQHRLIHRGERRYECDACGKRFYRADALKNHQRIHTGEKPFGCHFCTKNFRQRGDRDKHIRARHSHLDANARLMMQMQKLQLEAAAAQEQDSQKLATTSHSKDDMSTTNENMLPPEYNTAQVSYVRNNNLNDILMMGNVNFSKNVFESIMGDIIH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00200258;
90% Identity: iTF_00045685;
80% Identity: -