Basic Information

Insect: Calliopum simillimum
Gene Symbol: ZEB2
Assembly: GCA_951812925.1
Location: OX638368.1:50176591-50180150[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00034 0.041 15.6 0.2 1 23 336 359 336 359 0.94

2 10 0.094 11 7.9 0.1 1 21 452 472 452 473 0.94

3 10 1.9e-06 0.00023 22.6 0.2 1 23 481 503 481 503 0.97

4 10 0.0085 1 11.2 0.1 1 23 507 530 507 530 0.92

5 10 5.6e-06 0.00068 21.2 0.3 2 23 537 558 536 558 0.98

6 10 4.9e-08 5.8e-06 27.7 0.8 1 23 564 586 564 586 0.98

7 10 9.4e-05 0.011 17.4 0.1 1 23 592 614 592 614 0.98

8 10 9.5e-06 0.0011 20.5 0.5 2 23 621 642 620 642 0.97

9 10 0.00014 0.016 16.8 0.4 1 23 648 670 648 670 0.98

10 10 0.0043 0.52 12.1 4.0 1 23 676 698 676 698 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00034	0.041	15.6	0.2	1	23	336	359	336	359	0.94
2	10	0.094	11	7.9	0.1	1	21	452	472	452	473	0.94
3	10	1.9e-06	0.00023	22.6	0.2	1	23	481	503	481	503	0.97
4	10	0.0085	1	11.2	0.1	1	23	507	530	507	530	0.92
5	10	5.6e-06	0.00068	21.2	0.3	2	23	537	558	536	558	0.98
6	10	4.9e-08	5.8e-06	27.7	0.8	1	23	564	586	564	586	0.98
7	10	9.4e-05	0.011	17.4	0.1	1	23	592	614	592	614	0.98
8	10	9.5e-06	0.0011	20.5	0.5	2	23	621	642	620	642	0.97
9	10	0.00014	0.016	16.8	0.4	1	23	648	670	648	670	0.98
10	10	0.0043	0.52	12.1	4.0	1	23	676	698	676	698	0.98

Sequence Information

Coding Sequence: atgTCACTAGacgttgaaaaaatttgcagaACCTGTTTGGCCTTAAGTGGACCATTGTTATCAATTTTTGATGGTGCTTCTCAAGGTTCTGGATGCTTGGCTGACATGCTAAAAGAATTGACTAAATTTAAGcctTCCCCCGGAGACAAAATGCCTGATAAAGTGTGCCTCACCTGTATTAGTGAAATAAATCGATGCTATtcatttaaaatgaaatgtgAGAATTCCCGTAATACTCTGCATCAACTTATACCGGAGGCAATCATGGAAGAACTCACTCTGGAAAATCCAAAGAAAAAGGTCCGACCATCAACTAAATGCATACAAACGACGccggagaagaaaaaaaaatttgcaacagcTCAGGCGCAAACAATTGCGGAGGTAAAGGTACAATTCTGCCACCAGGAAGTGCAAACAGAGTTATGTACTAGTGATAAATCACCAATATCTGATAAATTTCAGAAGCAGGAACAAAGTTTGTCGCTTAAAATTGAAGAAGTATTTGCTGAAGAGCCACAAAGTATGACACGTAGCATAGCACGCttagcgaataaaaaacaaGCAGAACCAGAGAAAGTACTTGCCTTTAAGCGTTTAACACTAGATTCAGAAGACCGAAATTCTCAGCAAGCCATTTATGaactaaaaaaggaaaatgaacAAGATATTGACGATTTTGAAGATGCGGCTAACCAAATTGATGCTGATGAATTGGATCAAACTGCTTACTATGTTCTTTCTGATTCTCAGGGTGGTGAATATGTAGCAAATTATGATGTTGCTTCTAATTCGGATAATTATGAAGAAGAAATAGCTTACGGTGAAACTGTTACCGAACAGGAACAACAGATTACGAAAGAGGATTTTAATTTCACAATAATCAAGATCGAAGAGGGCGAAGAACAAATTGCTCCAGTCGCTGCTAAAACTCCAAGCACTGATTTAGCGCTTGCAACACCTTTGAAAACAGATCAGCTCTTATCTACAATAAAGAAATGCGAATTTAATTGTCCAGAATGTAACATGGACTTTGTTAGCGTAAATAATCTAAAGCGGCACGGCTTAAAAGTGCATAATTGGTCGTTAGATCAGATAAAAGTACTTGAAGAAGCacgattaaaaaaaacatccgaTAAGAAATTTCCTATACGTAAGACTTTATTAAAGCCTGAAGAAGACGTTGGAGATGATGTTGAGTTGCCGCCCGAGGTAGAAAAAGCGATCGTGCTAAAGATGGAAGTTGGTAGATGTCAACAggaagtaaaaaacaaaaattcgtcTTTACCGACTGTGACAGCACCAAAACATGAAGTATTTTTATCTGCTGCTGCATCTACTGATGCCATGAACTTTTTTTGCACACGTTGTGGTGCAGGTTTTGTATTACGAAAATCTCTTGGTATTCacatgaaacaaaacaaatgtgaaattcaaaattttgcatgTCCCGAGTGTAAACGTGTGTTTTCTTCGGAAGAAAGTTTGGAAGAACATTTAAAGACACATGAGTTCCAGTTCAACTGCGCCGAATGCAATATGATATATAACACCAACAGGGAACTGAGTCAACATTTAATAGATGTACATAATCGTAATCCCAAAAATCAATGTGAAGTCTGCAATAAAGTGTTTACAATGTTATCGGCACTAAAGGATCACTTACGTATACATAGCGGCGAAAAACCATTTGTTTGTCCAACCTGCGGCAAAGCATTTCGTCAAAATACAAATCTTAAACAGCATCTAATGCGACATTCAAATATAAAACCATTTCAATGCAATGAGTGCGCTTTAAGTTTTGTTAGTAAAGCAGAACTCATCTCTCACAGCCGCGTTCATTTCGGTGGTCATCCTTGGAAATGCGAATTGTGCGATGCTCGCTACACTACCTCTAGTTTATTGCTCAAACATATTCGAAAGCATACGGGTGAACTACCCTATGCTTGCGAATATTGTCCAAGGCGTTTTTCCGTCTTGAACGTATTGAAAAATCATCGTCGTATTCATACTGGTGAAAAACCATTTAAATGCATTTATTGCCAGAAAGCTTTTGCGCAAAAAAGTGCTTGTCAAACACATCAGCGCACGCATACTGGTGAAAAACCTGCATTTACACATTTATCTATATTACGCATGCATATGAAATTGCATGAAAAAGACAATATTGATACCGATGGCACAAAACGTAAACTTAGGTTTGCCACTAATAATGATGATGAATCTCCAGATCAAAAAATTAGGTCACAAATTCAGGATCAAAATGATGAGTCGCAGCAAGAAAGTGAAATAGCAGTGACTACTGAAGATGATcttataaaaattgatataactgATGGTTGTTGA
Protein Sequence: MSLDVEKICRTCLALSGPLLSIFDGASQGSGCLADMLKELTKFKPSPGDKMPDKVCLTCISEINRCYSFKMKCENSRNTLHQLIPEAIMEELTLENPKKKVRPSTKCIQTTPEKKKKFATAQAQTIAEVKVQFCHQEVQTELCTSDKSPISDKFQKQEQSLSLKIEEVFAEEPQSMTRSIARLANKKQAEPEKVLAFKRLTLDSEDRNSQQAIYELKKENEQDIDDFEDAANQIDADELDQTAYYVLSDSQGGEYVANYDVASNSDNYEEEIAYGETVTEQEQQITKEDFNFTIIKIEEGEEQIAPVAAKTPSTDLALATPLKTDQLLSTIKKCEFNCPECNMDFVSVNNLKRHGLKVHNWSLDQIKVLEEARLKKTSDKKFPIRKTLLKPEEDVGDDVELPPEVEKAIVLKMEVGRCQQEVKNKNSSLPTVTAPKHEVFLSAAASTDAMNFFCTRCGAGFVLRKSLGIHMKQNKCEIQNFACPECKRVFSSEESLEEHLKTHEFQFNCAECNMIYNTNRELSQHLIDVHNRNPKNQCEVCNKVFTMLSALKDHLRIHSGEKPFVCPTCGKAFRQNTNLKQHLMRHSNIKPFQCNECALSFVSKAELISHSRVHFGGHPWKCELCDARYTTSSLLLKHIRKHTGELPYACEYCPRRFSVLNVLKNHRRIHTGEKPFKCIYCQKAFAQKSACQTHQRTHTGEKPAFTHLSILRMHMKLHEKDNIDTDGTKRKLRFATNNDDESPDQKIRSQIQDQNDESQQESEIAVTTEDDLIKIDITDGC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00258205;
90% Identity: iTF_00258205;
80% Identity: -