Csim012183.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Calliopum simillimum
Gene Symbol
Aef1
Assembly
GCA_951812925.1
Location
OX638368.1:110367008-110369764[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00033 0.04 15.6 5.0 2 23 105 126 104 126 0.98
2 9 7.1e-07 8.5e-05 24.0 4.2 1 23 132 154 132 154 0.99
3 9 4.8e-07 5.8e-05 24.6 1.0 1 23 160 182 160 182 0.99
4 9 1.3e-05 0.0016 20.1 3.5 1 23 245 267 245 267 0.99
5 9 6.2e-06 0.00075 21.1 0.9 1 23 273 295 273 295 0.99
6 9 6.8e-07 8.1e-05 24.1 3.5 1 23 301 323 301 323 0.99
7 9 1.6e-07 1.9e-05 26.1 1.0 1 23 397 419 397 419 0.98
8 9 1.6e-05 0.002 19.7 3.2 1 23 425 447 425 447 0.99
9 9 3.7e-07 4.5e-05 24.9 2.7 1 23 453 475 453 475 0.97

Sequence Information

Coding Sequence
ATGCATCTCAACCATGCGACTGCCATGGCTAACTATCAACATTACCCGCCACCCAACATTCAACATGCAAATCAGCAGCAGACAACTATTACGGGTTTACAACAAAACCCTTTTACCCTGCATCAGTTAACCGCTGTGCAGGCGATTCAACATCCGACGCACCAGGCGATGCTGCATCCGCAACATCCACTGGTACATTTATTGGATATCTCATCAACGACTACTACACCGAATCCCACACCAACATCACCATCAAATATAGAAGTAGCATCTGAAGAGGAACCCGTGCCGGATGATCCGCGCAAAAAAAAGCAATGCCACGTCTGCAAGAACAAATTTCGCCAATTGACCACGCTCAGGAATCATATGAAAATACATACGGACGAGCGTccttataaatgcaagcactgcGACAAGACGTTTAGGCAAATTTCTACGTTAACAAATCATGTTAAGATACACACAGGTGAAAAACCATTTACTTGTAATATTTGCGCCAAGGATTTTCGACAACAAAGCACTTTGATTAATCACATAAAAACCCATAAGGAGTCGTCGACGCCAACTTCTTTGCTGAATTATCAGCCTAAATTGTCGCCATCGCATCGTCATCCAAAAGGTTCTCATGTGCAAATGGTCAACGCTTCACACCCAAACAATCGTGTGCCCATCTCAAAGAGTCTTTATTCTGGCAGCTATAACTCACCCCAGGCCGAGGAGCTAGTGAAGCCATACCAATGCAATATTTGCAAACGACGCTTCCCGCAGCTAAGCACGTTACACAATCACGAGAAGACGCACATTGATCCCAAGCCGTACAAATGTGAAACATGCGAAAAGACCTTTAGTCAAATGGCAACGCTGGCCAATCATAGAAAGATCCATACTGGTGATAAGCCCTACACCTGTTCCTACTGTTCAATGCAGTTCCGACAGCAGAGTACTCTGACCAATCACATGAAGACTCACACCACAGTCTCGCTTGCGGGCCCAACTCCAACACTTGTAACGTCATCAAACGCAACCATACAACATCATCTACAACATCTACAACCGGATCATCATCCACTACTTCATTTTCTCGATAGCACTACAACTGTCAGCACCGTGGTACCCAAGGCTGAATGCAAACAACCGGAACGATGCAATAGCAATAGCAGCATTTACATAGAAAGTCCCGATCGTCCTTTTCCGTGCAGCATTTGCCGGCGCGCATTCTCACAGCAGAGCACTTTGACAAATCACATAAAGACACACACCGGTGAAAAGCCGTACACTTGTAAAATATGCGAATCACACTTTCGTCAATTGTCAACATTGAATAATCACATGAAGATCCATACTGGTGAGAAACCGCATAGCTGTTCCTATTGCCCAAAACAGTTTCGTCAAAAGAGTACACTCATTAATCATATAAGAGTACATACTTGTTAA
Protein Sequence
MHLNHATAMANYQHYPPPNIQHANQQQTTITGLQQNPFTLHQLTAVQAIQHPTHQAMLHPQHPLVHLLDISSTTTTPNPTPTSPSNIEVASEEEPVPDDPRKKKQCHVCKNKFRQLTTLRNHMKIHTDERPYKCKHCDKTFRQISTLTNHVKIHTGEKPFTCNICAKDFRQQSTLINHIKTHKESSTPTSLLNYQPKLSPSHRHPKGSHVQMVNASHPNNRVPISKSLYSGSYNSPQAEELVKPYQCNICKRRFPQLSTLHNHEKTHIDPKPYKCETCEKTFSQMATLANHRKIHTGDKPYTCSYCSMQFRQQSTLTNHMKTHTTVSLAGPTPTLVTSSNATIQHHLQHLQPDHHPLLHFLDSTTTVSTVVPKAECKQPERCNSNSSIYIESPDRPFPCSICRRAFSQQSTLTNHIKTHTGEKPYTCKICESHFRQLSTLNNHMKIHTGEKPHSCSYCPKQFRQKSTLINHIRVHTC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00972421; iTF_00352585; iTF_00351994; iTF_01486505; iTF_00624915; iTF_01181331; iTF_01415222; iTF_01201051; iTF_01426948; iTF_00366650; iTF_01023230;
90% Identity
iTF_01486505;
80% Identity
-