Basic Information

Gene Symbol
-
Assembly
GCA_030142265.1
Location
JARQSU010000398.1:1359909-1363922[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 0.047 3.5 8.4 3.1 1 23 399 421 399 421 0.93
2 21 0.0015 0.12 13.0 0.1 1 20 429 448 429 449 0.96
3 21 0.0018 0.14 12.8 0.3 1 23 458 480 458 480 0.98
4 21 6.5 4.8e+02 1.6 0.1 2 23 507 528 506 528 0.78
5 21 0.045 3.4 8.4 0.8 1 23 536 559 536 559 0.92
6 21 0.0042 0.31 11.7 0.8 2 23 566 589 565 589 0.87
7 21 1.5 1.1e+02 3.7 0.2 2 23 622 643 621 643 0.91
8 21 0.14 10 6.9 0.6 2 23 652 674 651 674 0.93
9 21 0.00077 0.058 14.0 2.2 1 22 680 701 680 704 0.91
10 21 0.0003 0.022 15.3 6.5 1 23 788 810 788 810 0.98
11 21 0.0033 0.25 12.0 0.2 1 23 817 840 817 840 0.95
12 21 9.7e-05 0.0073 16.8 2.1 1 23 846 868 846 868 0.98
13 21 0.00066 0.05 14.2 2.1 1 23 874 896 874 896 0.97
14 21 2.1e-05 0.0015 18.9 0.8 1 23 902 924 902 924 0.97
15 21 0.13 10 6.9 1.0 1 23 937 960 937 960 0.96
16 21 0.00014 0.011 16.3 3.9 1 23 976 999 976 999 0.96
17 21 0.0011 0.083 13.5 1.3 1 23 1007 1030 1007 1030 0.96
18 21 5.5e-05 0.0041 17.6 1.6 1 23 1036 1058 1036 1058 0.98
19 21 0.0069 0.52 11.0 6.9 1 23 1064 1086 1064 1086 0.98
20 21 0.00012 0.009 16.5 3.1 1 23 1092 1115 1092 1115 0.98
21 21 0.075 5.6 7.7 5.4 1 23 1121 1143 1121 1143 0.97

Sequence Information

Coding Sequence
ATGAATTCTGCAAAAACGTTCATTGTGAAGGTAGAGAACTTACATATTACATTATCAGTAACAGACACATTTAAAGACCTGCAGATGaagttgaaagaaaatggGATAGATGTAAACATAGCGTCGATGCTAATTAAAGGAAGAATGGTAAATGAATCTTCTGTTGTATCAGAGTGCCTTAGTGTCgaaagtAAGGATGTAGAGGATGAGACCGTAGAATTTGTATTACCAGATTTATCTGAAATGTCAGAAACAGAAATGATTTCTGATCAAGatgTTGAGACTCAAAAGATTAAGTATTCATTGTGTCGATTATGTGGTATGACGGCAGAAGACccaattgatatttttgaggaatcaaatattatggaaacaataaacaaattattaccGATATCTATATGTCAACGAGAAACATTATCACGATACATATGCAGCCCATgccataagaaaattattttcattcaggattttgttttactttgtatagaaaatgaaaaaaaattgtcaaatctaACTACTTCAACAAACCAATCCATTGAAATTCCAGTGAATGACAATACAGAAGTTGagaaattattgcaaatacatgacaaaagaaataaatacagatGTCCCAATTGCAAAGTAAATCTAATCATCTCCAAAGATGTTCAatcagaaaattttgatactgCCTTTCAAATAACTTTAAATTCAACAGATAGTACAGATGAATCTGAAATAAATGCagagataaagaaacaaaaaacggATGTTGTATCACGGAAAAGTACACACAAAGGAATAAGTACCAGATCGGTAAGAAATTTACGATCATCTTccaatttacttaaaaaaagtaatacagtTAGTGCAAGACATACGAGAAGGCAAACACAGAATATATCTAGACctacaaaatcaaatattacaGAGAACcatgcaaaaaatataaataacagtttaaataaaaaatctcgaGAAAAGAGTAAAACTAATTTGCGAGATATCAGAAAGAGAATAGCGAATAGCGATCatgacaatgaaaaacatACACAGTCAccaaagaggagaaaaatgatttctgaGACGacagaaaatacttttcttacAATTGATCTGAATTTGAATGTTTCTAATACTACCGGTGAATTCGTTGAATTTGATACTCTGGAGGAAAGTAAGGACGAGAGTATAAAAAGGCCAATGAAACATAAATGCGATATATGtgatttagaattttcttcgGAAGATCATTATCGGTTTCATGTGGATCGACACGAGACGGGATGTTTCGATGATTTTAAATGCCCTACATGTAACAAAGAATTATCCTCTGAGGATAGCTTATGGGAACATCAAGAATGCTGTGAAATAGATCTTGAATACTATAGTTGTACGGTATGCCAGGAAACGTtccttgaaaaagaattattaaatgatcATATGCAAATTCACGATCaagaggatgaaaaatctCTTAATACAGATACGGATACAGTTCAAtcagaaaatggaaaaaaatcaactaaATTAACGTGTGAAGTATGTGGAGCGCGCTATGTATTACGGGAAcgatatgaatttcatatagAAAGACATAATTTTGGAAACATCAAGACTTTTTCATGTCtaatttgtgaaaaaagatttaagaGTGAAAACATTTTGTGGGATCATTACCAATATCAACATAGAACAGGCGAGAAATTCGCTTGTATAACTTGTGAGAAAACATTTGTCAAACGAGCAAACTTGAATTATCACTTAAAAACATTTGGCCACAAGGGTGGAAAATTCGTGAACAGCATAGAGCATAATCAAAGCACCGACTCCAGTAACGTGAAACTGTCTGATATTGGTAAACCACGACCTAAGATAACTTGTTTAGAATGCGGAGCTCGTTTTGTTTTACAAGAAAGATATGAATTCCATATGGAAAGACATAAATCTGGAAAAATGGATATTTGCGTATGCAATCTGTGCGGTAGAGAATcaacaaatgaaaatgttttgtGGGATCATTATCAGTATATGCACAAACGCACGAAACGTTACGTTTGTACTACAtgtggaaaattatttcacaaacAGTCAATGTTGAGTAGACACCAAGTCAAATATGGTCACAAAGGTACAAAAGAAATAGATATCGAAACGGATGACAATGCTATAACAATAGACAGTGCTGCTTTTAAAAAGGTCATAGCTGAAGAgataatagaaatgaaatcaGTGAATTGCGTACTCTGTGGAGAAGTAGTATGGGGTGTGGACCCAAATTTGATAAACGATGCTGTTACCTGTTCGAATTGTGAGAGACCAGGACTATCTTTGCAAGTAGATTCCGACGGTGCTAAGGTAATATCACGTCGTCAGTACCACTGCAACATGTGTAACAAACATTTCACAACGAAAGATCGCCTGGAGTATCACATAATGCGCCACTCGGAAAATATGGAGGAATTTGTTTGTAGTACTTGTGGAAAGGAACTCAGTACCGAACAAGCTTTGTTTGAGCATTACTTATACGTGCATAAAGGTGCAAGACCACACGTTTGTGAGCTTTGTGGAAAATCTTATCAATTCAAGGCTCGGTTAAAGGAGCATATGAGAAGTCATAGTGGAGAACGACCATTCGCCTGTGAAATATGTGGTCAACGATGTATGACGAATAATGCGCTACGGTCTCACAAAAAAACTCATATCACAGAGAAGCGATTTCCATGTCAAATATGTAAGAAGGCGTTCAGAAAAAGGCAGGATTTGAACGAACACTTGGAGAGACACTGGAAGAATGACAAGACGATGACGTTACCACAAGTGTTTAGTTGTTCTATATGCATGGAGATGTTTCCGACTTTTCGGATTCTAAAAAAGCACATGAAAGAGACTCATAGTGTGGAGAGTCAGGATCCTATATTGACTGAATTGCAACCATGGTTTGAGTGCGAAGACTGTCACGAGAAGTTCAAGCATCAAATGTCTTTGAAAGTTCATCGTGAGAGGGTTCACGAGGGTAAAATGAAGCCCGTTTATCATTGCGACATATGTGATATCACATATAAGAATGCGCGGGTACTCTcgaatcatattaaaaataaacacgAGGGTGGTAAACGGTATAAATGCGCTCAATGCGGCAAAGAGTACAATCAGTCTACGTCTTTAcataatcatattttattgcataCTGGAGAAAAGCCGTTCAGTTGTGAACATTGCGAAATGACGTTTCGCACTAAGGAATCCCGCGATCATCATCAACGAAAACATACTGGAGAGCGTCCTTATAAATGTCCACATTGTGACAAAGCATTCGCTACTACAACTCAACGTCGAGAGCATCGAAAACGAGAACACGACGAAGGCAATAATCATCATTGTCCGGAATGTGGGAAAGTATGTTTTGGCGAACATGGCGTTAGAAGTCATTTAAATACTCATATGGCCGAGAAACAGCAGTCACAGAATGATATTACGTGA
Protein Sequence
MNSAKTFIVKVENLHITLSVTDTFKDLQMKLKENGIDVNIASMLIKGRMVNESSVVSECLSVESKDVEDETVEFVLPDLSEMSETEMISDQDVETQKIKYSLCRLCGMTAEDPIDIFEESNIMETINKLLPISICQRETLSRYICSPCHKKIIFIQDFVLLCIENEKKLSNLTTSTNQSIEIPVNDNTEVEKLLQIHDKRNKYRCPNCKVNLIISKDVQSENFDTAFQITLNSTDSTDESEINAEIKKQKTDVVSRKSTHKGISTRSVRNLRSSSNLLKKSNTVSARHTRRQTQNISRPTKSNITENHAKNINNSLNKKSREKSKTNLRDIRKRIANSDHDNEKHTQSPKRRKMISETTENTFLTIDLNLNVSNTTGEFVEFDTLEESKDESIKRPMKHKCDICDLEFSSEDHYRFHVDRHETGCFDDFKCPTCNKELSSEDSLWEHQECCEIDLEYYSCTVCQETFLEKELLNDHMQIHDQEDEKSLNTDTDTVQSENGKKSTKLTCEVCGARYVLRERYEFHIERHNFGNIKTFSCLICEKRFKSENILWDHYQYQHRTGEKFACITCEKTFVKRANLNYHLKTFGHKGGKFVNSIEHNQSTDSSNVKLSDIGKPRPKITCLECGARFVLQERYEFHMERHKSGKMDICVCNLCGRESTNENVLWDHYQYMHKRTKRYVCTTCGKLFHKQSMLSRHQVKYGHKGTKEIDIETDDNAITIDSAAFKKVIAEEIIEMKSVNCVLCGEVVWGVDPNLINDAVTCSNCERPGLSLQVDSDGAKVISRRQYHCNMCNKHFTTKDRLEYHIMRHSENMEEFVCSTCGKELSTEQALFEHYLYVHKGARPHVCELCGKSYQFKARLKEHMRSHSGERPFACEICGQRCMTNNALRSHKKTHITEKRFPCQICKKAFRKRQDLNEHLERHWKNDKTMTLPQVFSCSICMEMFPTFRILKKHMKETHSVESQDPILTELQPWFECEDCHEKFKHQMSLKVHRERVHEGKMKPVYHCDICDITYKNARVLSNHIKNKHEGGKRYKCAQCGKEYNQSTSLHNHILLHTGEKPFSCEHCEMTFRTKESRDHHQRKHTGERPYKCPHCDKAFATTTQRREHRKREHDEGNNHHCPECGKVCFGEHGVRSHLNTHMAEKQQSQNDIT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00293924;
90% Identity
iTF_00293924;
80% Identity
-