Basic Information

Gene Symbol
-
Assembly
GCA_035041755.1
Location
JAWNKX010000242.1:6207485-6208792[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 6.7e-05 0.0057 17.3 3.4 2 23 13 34 12 34 0.97
2 10 0.0011 0.097 13.4 0.2 3 21 62 80 60 81 0.93
3 10 0.029 2.4 9.0 4.3 1 23 128 151 128 151 0.98
4 10 0.0057 0.48 11.2 0.2 2 23 189 211 188 211 0.94
5 10 4.1e-05 0.0035 17.9 0.7 2 23 239 261 238 261 0.95
6 10 0.024 2 9.2 5.1 1 23 275 297 275 297 0.95
7 10 5.1e-05 0.0043 17.7 0.5 1 23 303 325 303 325 0.98
8 10 4.8e-08 4.1e-06 27.2 1.6 1 23 331 353 331 353 0.98
9 10 1.6e-05 0.0014 19.2 5.2 1 23 359 381 359 381 0.98
10 10 0.00046 0.039 14.6 0.4 1 22 387 408 387 411 0.90

Sequence Information

Coding Sequence
ATGCGTACAGTTCACACAGATTTGCCTAACTTAATGCCCTGCCATTGGTGCAATCGAACATTTTACCGCCGCGACTACATGCTGAAGCATTTGAAACGCCACGgaataaaagagaaagatCTGCCTCTCGCTGAGATGTACATTAGCGCCACCTCGAAGGCCAATGGTGCGAAGTTTGTTCACTGCAAGGTCTGCAATTTGCAGTTCGACCGCATTTCGGAGTTAAAGGAGCACATGATAAGCGACCTGAAGCTGAACATAATCAAATATGAAAACATAAATTCTGTGAGCAACTATTCTATTACCAATGAAGCAGGCTTCGAGATGCACATCGATGATTCGGACACTGAAAATGAGGACCACACAAATGGGCGGGCCCCTTTCACATGTGCGCTCTGCCAAGTGCagtgcaaaagaaaatttgaaatgtttcAGCACCAGCGTTCGATGCATCGCTTCGAGCAGATGCCGTACTCGTGTCAGAAGTGCATATTCAAAAGTGTATCAAAGGATATACTCGAGCACCATGAGCGAACGCAGTGTTTGAGCACAGAGAAAACGTTGTCGTGTGAGAAGTGCGGATTGAAGTACATGTGGCCCGAAAATCTTACGCGTCATTTGAATCTACAgcatttcaatgaaatatCTCTCCAAAATATCGATGACAACACGGAGGAGCTAAAACATAAGACGGAACCACCTCTGCCTACACTGGAATGCCCACATTGTGACCGCACCTACGTACTACGGTCACGCCTAAATAATCACATTCGCGATGTTCATGTTGCAAGCGTACCGAAGAAAATAAGGGGAACCCAAagatttttgtgttcgttttgTGGCTATGAGACACATTCATCATCCTGCTTTGTTATTCATATGCGCAGACACACCGGCGAAAAACCCTTCAAGTGCGATTTGTGCGAGTTGGCATTTCCACGTCGCTCAGAAATGGTGCAACATCGCCGGAATCACACAGGCGAGAAACCGTATCATTGCACCGTATGTGGTAAGGACTTTGCTCGTCCTGACAAGCTGAAGCGGCATATGTTGACACATAGCGGATTAAGACCATATAAATGTAACTtttgcgataaatgttatcgTCAATCGAAAGATCTGAAGCTGCATCTCTTGCAACACACCGGAGAGTCTCCGTACGTGTGTAACGTATGCGGCGAAAGATTCCTACAAAATGCGACGCTTGAAAAGCATCGTAGTATGAGACGTCATTTTGAAGGAAAGAATACATAA
Protein Sequence
MRTVHTDLPNLMPCHWCNRTFYRRDYMLKHLKRHGIKEKDLPLAEMYISATSKANGAKFVHCKVCNLQFDRISELKEHMISDLKLNIIKYENINSVSNYSITNEAGFEMHIDDSDTENEDHTNGRAPFTCALCQVQCKRKFEMFQHQRSMHRFEQMPYSCQKCIFKSVSKDILEHHERTQCLSTEKTLSCEKCGLKYMWPENLTRHLNLQHFNEISLQNIDDNTEELKHKTEPPLPTLECPHCDRTYVLRSRLNNHIRDVHVASVPKKIRGTQRFLCSFCGYETHSSSCFVIHMRRHTGEKPFKCDLCELAFPRRSEMVQHRRNHTGEKPYHCTVCGKDFARPDKLKRHMLTHSGLRPYKCNFCDKCYRQSKDLKLHLLQHTGESPYVCNVCGERFLQNATLEKHRSMRRHFEGKNT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-