Basic Information

Insect: Bruchidius siliquastri
Gene Symbol: topi
Assembly: GCA_949316355.1
Location: OX438535.1:23767190-23774043[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0021 0.16 12.7 2.1 2 21 95 114 94 115 0.94

2 14 3.5e-06 0.00026 21.4 1.5 1 23 140 162 140 162 0.96

3 14 0.017 1.2 9.9 3.3 2 23 169 190 169 190 0.95

4 14 0.0089 0.66 10.7 0.4 2 20 209 227 208 229 0.89

5 14 0.00041 0.031 14.9 1.1 2 23 271 292 270 292 0.97

6 14 1.7 1.2e+02 3.6 0.0 1 21 298 318 298 319 0.89

7 14 0.0023 0.17 12.6 3.4 2 22 335 355 334 358 0.88

8 14 0.015 1.1 10.0 0.1 1 23 469 492 469 492 0.96

9 14 0.0041 0.31 11.8 0.2 1 23 496 518 496 518 0.97

10 14 6.8e-07 5e-05 23.7 2.4 1 23 524 546 524 546 0.98

11 14 0.058 4.3 8.1 0.3 1 23 552 577 552 577 0.95

12 14 0.066 4.9 8.0 2.9 1 23 583 605 583 605 0.86

13 14 1e-05 0.00075 20.0 0.6 1 23 611 633 611 633 0.98

14 14 1.4e-06 0.00011 22.6 1.9 1 23 639 662 639 662 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0021	0.16	12.7	2.1	2	21	95	114	94	115	0.94
2	14	3.5e-06	0.00026	21.4	1.5	1	23	140	162	140	162	0.96
3	14	0.017	1.2	9.9	3.3	2	23	169	190	169	190	0.95
4	14	0.0089	0.66	10.7	0.4	2	20	209	227	208	229	0.89
5	14	0.00041	0.031	14.9	1.1	2	23	271	292	270	292	0.97
6	14	1.7	1.2e+02	3.6	0.0	1	21	298	318	298	319	0.89
7	14	0.0023	0.17	12.6	3.4	2	22	335	355	334	358	0.88
8	14	0.015	1.1	10.0	0.1	1	23	469	492	469	492	0.96
9	14	0.0041	0.31	11.8	0.2	1	23	496	518	496	518	0.97
10	14	6.8e-07	5e-05	23.7	2.4	1	23	524	546	524	546	0.98
11	14	0.058	4.3	8.1	0.3	1	23	552	577	552	577	0.95
12	14	0.066	4.9	8.0	2.9	1	23	583	605	583	605	0.86
13	14	1e-05	0.00075	20.0	0.6	1	23	611	633	611	633	0.98
14	14	1.4e-06	0.00011	22.6	1.9	1	23	639	662	639	662	0.98

Sequence Information

Coding Sequence: atgaacAGTCTCGAGGCGATCGTGATTAATGTTTACAAATTAACAGAGAAAGGTAGCGTAATTTCTGCTGTGAAGCACGAATTGGACCCAAACACAAAGGAAATAATAACTAGAAGGTGTTTCACGACCGAAAACCTAACTTTCAAGCTCTTCGACgacgaaaaattgaatttgaactGCCAGCGTTTTCACCTAGGAGATAATCTGCTGAAATGCATAAAACTGGAAGACGCTCTAACTCTGCCAGTAGAAAAATGCGTGTTGAATATTCCAACGATGATAAGATGTCAAAACTGCGAGACGAACTTTCCTACAAAGTATCAATACCAACGGCATCAATGTGAATTCAACGCAGAAaagGTAATCTTGAAGCCGGATACTGATCTCAAACAAGCCGAGCCAAATATCCGAGAAAAGTATATCTGTGACGTTTGCAATAAGCAATTCGTGAGTAGAAGTAATTTGGAAAGGCACCATGTCAGCCATGAAAACGTCGAAAACAACGTCTGCGAGCACTGCAAGAAGCAGTTCGTGAGCGAGAATCGTTTAAAGACACACAAAGAAAATCACTGCAAGAAAGCCGGAGACCTGTCAAAGTTCTACAGAAGTGACGTGGCGGTATGGAAGTGCAAAAAGTGCCACGAGGTGTTTTCATCTCAAGTCACCGCTACTTATCACGTTTCAATTTGCACTGAAGTGGTAGAGATAAACAGCGAAAATGGAGACATTAGCAACAATGAAACTGAACCCTTGATTCAGAAGGAAGATTGTGGGGTGAATGTTGAGAAATTGCTCACTGAAATCTTGCTGCAGTGTGAGTTTTGTAATAGGACTTATGCCGAAAAAAATTTACTGCTGATGCATCAGAGGAAGCATACTACCGCAAAGAACTATGAATGTGTTAACTGCGCACAGGTTTTTGAATCGTACGCAAGTGCAGCCCAACACTGGATGAAGAAATGCTCAGAATACGTCAGTTTGTTCTACCTTCCAAAACTGACTTACTGCGAATATTGTGATAGAACTTTTAAGTCACACGAACTGCTTTATACGCATAAAATCAAGAAAAAGCATTACACTTCCAAACTACATACTCCTAGTACCAGTGAAGAAGCTGAAACTGCAACTAAAAAAgagaaatgcaatgaaaataaaGAGGTATTGAATAAGTTGATCGAAGATGTACTGAAAACCTTGGATGTGCCAGTAAACAAAATCGGAAACACGTTGTCCACAACAGAAACCAACGGAGAGATAAAAATCAAAGACGAAACCTTGGATTTGAGTAACAAAGAGAACGAAATCAAAGTGGgtgaaaagaaaaaaagaggCAGAAAACGAAAATGGCCGAAAGAGGATGTCAAAATGAAAGTTATAAGCTCAGAAGTAGATGAAGGGTTCAAGTATCAATGCGAAAGATGCATCAAGGTGTTCGGAAATGTTGCTGATCTGGAGGCTCACAGAGACAAAGAGCATGCGGCTAGCTTCACTTGTGAAGAATGTGGACAGGTTCTCCATAGTGCCAAAGCGTTGCTTATTCACAGTAGAGCTCACAAAAGCCTAAAACCATATGTATGTGAAACTTGCGGTCGAAGTTACTCTCAAACTTCACATTTGTGGCAGCATATGCGTTTCCATCAagGAATAAAGCCGTTCGCCTGTCCGCATGAACGATGTGAGGCCAGATACACCATCCGTCCCGATCTGAAGGACCACATCCGTAAGGTGCACACCAGAGAGCGGCCCTTTAAGTGCAACGTCTGTGATAAGTGTTTCCTAACCGGATCAGTGTACTACCAACACCGACTGATCCACACCAACGACAGAAGATACGCTTGCGATCTTTGTACGAAGAGATTTTTTAGAGCTGATGCTTTGAATAACCACAGAAGAATTCATACCGACGAAAGGCCGTATCCTTGCCATGTATGCGGCAGAGAATTTAGGCAGAAAGGAGACAGAAATAAGCATATTCGTACTCAGCATCCTGATGCCATTTTCGTTTAA
Protein Sequence: MNSLEAIVINVYKLTEKGSVISAVKHELDPNTKEIITRRCFTTENLTFKLFDDEKLNLNCQRFHLGDNLLKCIKLEDALTLPVEKCVLNIPTMIRCQNCETNFPTKYQYQRHQCEFNAEKVILKPDTDLKQAEPNIREKYICDVCNKQFVSRSNLERHHVSHENVENNVCEHCKKQFVSENRLKTHKENHCKKAGDLSKFYRSDVAVWKCKKCHEVFSSQVTATYHVSICTEVVEINSENGDISNNETEPLIQKEDCGVNVEKLLTEILLQCEFCNRTYAEKNLLLMHQRKHTTAKNYECVNCAQVFESYASAAQHWMKKCSEYVSLFYLPKLTYCEYCDRTFKSHELLYTHKIKKKHYTSKLHTPSTSEEAETATKKEKCNENKEVLNKLIEDVLKTLDVPVNKIGNTLSTTETNGEIKIKDETLDLSNKENEIKVGEKKKRGRKRKWPKEDVKMKVISSEVDEGFKYQCERCIKVFGNVADLEAHRDKEHAASFTCEECGQVLHSAKALLIHSRAHKSLKPYVCETCGRSYSQTSHLWQHMRFHQGIKPFACPHERCEARYTIRPDLKDHIRKVHTRERPFKCNVCDKCFLTGSVYYQHRLIHTNDRRYACDLCTKRFFRADALNNHRRIHTDERPYPCHVCGREFRQKGDRNKHIRTQHPDAIFV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00260841;
90% Identity: iTF_00260841;
80% Identity: -