Basic Information

Insect: Bradysia odoriphaga
Gene Symbol: Zfy2
Assembly: GCA_016920775.1
Location: JAFDOW010000398.1:352392-354562[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 4.3e-07 2.2e-05 24.5 0.9 3 23 222 242 221 242 0.97

2 9 0.00015 0.0075 16.5 1.7 3 23 250 268 249 268 0.98

3 9 0.00025 0.012 15.8 0.3 1 23 274 296 274 296 0.97

4 9 3.6e-05 0.0018 18.4 2.6 1 23 303 325 303 325 0.98

5 9 8.4 4.3e+02 1.6 0.2 2 14 347 356 346 366 0.64

6 9 1.1e-05 0.00056 20.1 1.6 1 23 372 394 372 394 0.97

7 9 6.1e-05 0.0031 17.7 4.1 1 23 400 422 400 422 0.98

8 9 0.00033 0.017 15.4 0.7 1 23 428 450 428 450 0.97

9 9 0.0021 0.11 12.9 0.7 1 23 457 480 457 480 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	4.3e-07	2.2e-05	24.5	0.9	3	23	222	242	221	242	0.97
2	9	0.00015	0.0075	16.5	1.7	3	23	250	268	249	268	0.98
3	9	0.00025	0.012	15.8	0.3	1	23	274	296	274	296	0.97
4	9	3.6e-05	0.0018	18.4	2.6	1	23	303	325	303	325	0.98
5	9	8.4	4.3e+02	1.6	0.2	2	14	347	356	346	366	0.64
6	9	1.1e-05	0.00056	20.1	1.6	1	23	372	394	372	394	0.97
7	9	6.1e-05	0.0031	17.7	4.1	1	23	400	422	400	422	0.98
8	9	0.00033	0.017	15.4	0.7	1	23	428	450	428	450	0.97
9	9	0.0021	0.11	12.9	0.7	1	23	457	480	457	480	0.95

Sequence Information

Coding Sequence: ATGGAAATTGAGAAAGAAGAGAATATCATCATTCGATACATTCCTCAATACATCGTAATTGAAACTCGTTACAAGCCGCTGCAAACGCATGTTGACCCACAACCAGTTTCAAAAACTGTATGCAACAgcgtaaaatatgaaaatgaggcTAGAATTGAATCGGAAACTTCATTTCAATACGTCCAGGCCGATCAATACTATGCCATCGACGATGATGACAATGAATGTGCAGAAGTAAAACAAGAAAACTTTGAGGATTACACCGATGACGGCAGGCCACACGCAAAAACGAGTCCAACGAAGCGAGATTGCAATAGCAAATCCAGACGATTGCTAAATGAATGGTTCATGAGTAATCTGCAGAATCCTTACCCCACCGAAGAGCAAAAGGAAGTCCTAATGTCACAGACAAATATGACCAGGGTTCAGGTTAACTACTGGTTCATCAACAAACGGAAAAGGAACAAACATCTCTTGAATAATGCAAAGAAACCAACCAGCGGTATTGATCTGCTTGACGATGTAGAAAATGCACTTTTAGGCGATACCCCGCCCGACGCTGACGGTACTACTGTTGAGCTGGAAGTAACCATACAATCAGATTCGGCGCGAAAACGTCGACGAAAAAAAGTGATTGCTGAACAGGAACAACTACCTGAGATATGTGATGTGTGCGGGAAATCGTTCACCCAGCGGTACATGTTGCAATCCCATTTGAAACGGCATGATCCAAGTACGTGGGAAGCGTGTCacatttgtaagaaaagttttcCGGATGGTTTGAAACGTCATATGCGAGTCCATTCCGGTGAAAGGCCTTACGTTTGCCACGTCTGTGGCGCTTCGTATAAACAAGCCTACGTCTTGACGATGCACAAAGCAATACACAACGAGTCGGGTGAATTATTTTACTGCGACACTTGCAACAAAGGTTATAGGAGTAAATACACTCTGAAAGACCACTTGAAACTGCACTACCGTGTAAGGAACGATGACTCAGCCTTGGTGGTGATGAAAAGTACCTGGAAACCGGCCAAAGTTTGTACAATTTGTGGATTCGAAACGTACAACATAAGATCGCACATGATAGCCCGCCACTCAACGTTACGTCCATTCAAATGTGAAATTTGTCCCGAAACGTTTAAATTTAAGAAAGATCTGCAAACGCATTATGCCTACCATTCGGACGAAATGAATTTCCACTGTGACGAATGTGAGAAACGGTTCAAAACCAAACGAAAACTGGTCATACACAAACGGATACACACGAACGAAAAATCGTACGTATGTGAGGTATGCGATAGGTCGTTTCTGCTCAGCACATACTTGAGAAAACATATGAGTTTGCATACGGGTGAAAGGAAGCGGCACGCTTGCACGGAATGTTCGAAGGACTATTCGGGAATAACGGATTTGCGGCGCCATTTGGAAAGGGAGCATGGGATTAAGGTTCAACCGAATCCAAAGTATGCAAATAACAACATGACCAAGAAGCATAAAGTATTATAA
Protein Sequence: MEIEKEENIIIRYIPQYIVIETRYKPLQTHVDPQPVSKTVCNSVKYENEARIESETSFQYVQADQYYAIDDDDNECAEVKQENFEDYTDDGRPHAKTSPTKRDCNSKSRRLLNEWFMSNLQNPYPTEEQKEVLMSQTNMTRVQVNYWFINKRKRNKHLLNNAKKPTSGIDLLDDVENALLGDTPPDADGTTVELEVTIQSDSARKRRRKKVIAEQEQLPEICDVCGKSFTQRYMLQSHLKRHDPSTWEACHICKKSFPDGLKRHMRVHSGERPYVCHVCGASYKQAYVLTMHKAIHNESGELFYCDTCNKGYRSKYTLKDHLKLHYRVRNDDSALVVMKSTWKPAKVCTICGFETYNIRSHMIARHSTLRPFKCEICPETFKFKKDLQTHYAYHSDEMNFHCDECEKRFKTKRKLVIHKRIHTNEKSYVCEVCDRSFLLSTYLRKHMSLHTGERKRHACTECSKDYSGITDLRRHLEREHGIKVQPNPKYANNNMTKKHKVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00245722; iTF_00245307; iTF_00246238;
90% Identity: iTF_00245722; iTF_00245307; iTF_00246238;
80% Identity: iTF_00246238;