Basic Information

Gene Symbol
-
Assembly
GCA_016920775.1
Location
JAFDOW010000900.1:2450268-2453171[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 5.6e-06 0.00028 21.0 0.6 1 23 104 126 104 126 0.98
2 16 2.5e-06 0.00013 22.1 0.1 1 23 132 154 132 154 0.97
3 16 3e-06 0.00015 21.9 3.6 1 23 160 182 160 182 0.99
4 16 1.9e-05 0.00096 19.3 1.4 2 23 189 210 188 210 0.97
5 16 1.9e-06 9.4e-05 22.5 0.1 1 23 216 238 216 238 0.97
6 16 8.5e-05 0.0043 17.3 1.3 1 23 244 266 244 266 0.97
7 16 1.7e-05 0.00084 19.5 0.4 1 23 272 294 272 294 0.97
8 16 1.2e-06 6.3e-05 23.0 2.0 1 23 300 322 300 322 0.96
9 16 5.7e-05 0.0029 17.8 1.1 3 23 330 351 328 351 0.97
10 16 1.8e-05 0.00092 19.4 2.0 1 23 512 534 512 534 0.98
11 16 3e-06 0.00015 21.9 1.2 3 23 542 562 540 562 0.97
12 16 1.4e-07 7.3e-06 26.0 1.7 1 23 568 590 568 590 0.99
13 16 6.7e-05 0.0034 17.6 0.8 1 23 596 618 596 618 0.96
14 16 0.00028 0.014 15.6 0.9 1 23 624 646 624 646 0.97
15 16 9.3e-07 4.7e-05 23.5 0.2 1 23 652 674 652 674 0.98
16 16 0.013 0.65 10.4 2.1 1 22 680 701 680 703 0.90

Sequence Information

Coding Sequence
ATGTTGAAAGcTTCAACCAGGACCGTTGAAAAAGTGTGGCTTAAAACTGAACCTACCTACGAAGAATCTAGTGATGTAGTAGACCTAATCACATCACCGATATCAACAGTCAGCTCTACGATAAAGAAAGAGGAAACTGAGATTGTGCACATCAAATCCGAATTACCGTTAGACGTACTTGTTGGTACTCCGTCATCAATCGCGGAGTCAGCGAAGGATACAAAGGACAAATTCAGCAGTAAAGTTCTCAAGAAATCAGATTGCGACAAAACGGGTAAACAAGATATCCAGCCACCCAAAGTAAAGCCGTTTGTCTGCAGCGAATGTGGTGCGAGATTCGCATTGAAACGTACTCTTCAGAACCATCAACGAACCCATACCGGAGATAGACCTTTTGTCTGTGACTTATGTGGAAAGAGCTTCGCCGTAAAAGCTGGTCTCACCCGTCACATCCTATTACATTCAAATGTAAAGCCTTACACTTGTTCAGAATGTGGTAAAGGATTCAGGCAAAGCTGTCAATTGAAATCACATACATTGACGCATGCCGGGGTCAAACATCTGGTTTGCGAGCACTGTGGAGCAAAGTTTTCAACGACATCTGGCTTCCGAATCCATCAACGATCGCATAGTGGAGAGCGGCCCTTTGTCTGTTCGGAATGTGGAGAGGGATTCGTTCGGAGAGCGGCTCTCACCAGACACATGCTTGATCACTCCGGTGAAAAAAGATTCGCTTGCGACCAGTGTGACATGAGattctttcagaaaaatttGTTGCAATCACATCAGAAAATTCACGCAGATCATAAGCCCTTCGTTTGTGTTGAATGTGGGAAAGCATTCTACCACAAGGCCGGTCTAAAGTCACACGAAGCGACGCATTTGTTAGTTAGGCCGCATGCATGCCATATATGTGGTAAACGATTCATTCAAAGCGGTACGTTGAAGATACATATGGTTACGCATAGTGACGTAAGGCCCTTTGGTTGTGAAGTTTGTGACATGAGATTCACACAAAGTTTTACCTTGAAGACTCACATGCTGAAGCAGCATGACCAACTACCAACACCTAGACTGAAACAAAACCTGAAGATGCGAAATCGACAATCTGCCATTGAGTCAGATGTGAAAAGTGATAACTACGTTGGGAACGTGGCAGGCACACATTCATCACATAGCTTAGATATGATTTCGTTGCATAATGGAAAACAAAACTCGGATCGAACGACCATCGATGACAGATCCAATGATGATGGAAAGTTAACACCGGAAACCTCAGAaaccaaatcaattttcaaGGCAGACAATGACGACAGAATCAATAATTTGAACGAGAACGTTGAGGAAAAGCTCGAAATGCAACAAATGGAACATATTGGTGCAATGGAAATTAGAATCGACCAAGTAAAAGTGGAATCGGAGGAcgcttttgaaaatttgagttATAGTGATGACAGTCAAGAAGAGAAACAAACGTTCAGTCACAAACAAAGTTCTTTTAAAAGTGCACGAAGTCCATCGCTGGAACTACAGTTCTCTTGCGACAAATGCGATCAAACGTTTTTGACAAATGCGGATCTGAAAAGGCATCAACGGAAGCATCGAGAGCGCACTCAAATAATCTGTGATGAATGTGGCAAAGGATTCAAGCATAACTATTTGCTTGAAATGCATAAACGCACCCACTCTGGTCAGAAGCCGTTCAAGTGTGATAAATGCGGAGCCACCTTCGCCCAAAGATCTAACTTAAACACACACAAACGTACCCATTCGAAACAGAAACCATTTTCCTGTGATGTATGCTCAATGGGCTTTACAACGAAATCTAGTCTGAAAACACACAATCTAATCCATACAAATGAAAAGCCATTTGCTTGTGATATTTGTGGCATGAGATTCACGGTTAAGTACAAAGTAAAGCTCCATAAAAATACCCACAGCGGGGAAAAGCCTTACATTTGTGAACTATGCGGTGCGTCATTTGGGCAAAAAAGTTACTTGAAAAAGCATATGCTAGTACATAGCGGTATAAAGGCCTATTCGTGTGACGAATGCCCATCCAAGTTTAGCACAAAATGCGCATTGGTCCAGCACAAGGGATACTCTCATCGCGGAGTCGACGAACTCTCACCCCGGCATAGACGTAAAAtgcagaaaatgaaattaatagcAGCGGGTCTCCTGACAAACGTAAGTTGA
Protein Sequence
MLKASTRTVEKVWLKTEPTYEESSDVVDLITSPISTVSSTIKKEETEIVHIKSELPLDVLVGTPSSIAESAKDTKDKFSSKVLKKSDCDKTGKQDIQPPKVKPFVCSECGARFALKRTLQNHQRTHTGDRPFVCDLCGKSFAVKAGLTRHILLHSNVKPYTCSECGKGFRQSCQLKSHTLTHAGVKHLVCEHCGAKFSTTSGFRIHQRSHSGERPFVCSECGEGFVRRAALTRHMLDHSGEKRFACDQCDMRFFQKNLLQSHQKIHADHKPFVCVECGKAFYHKAGLKSHEATHLLVRPHACHICGKRFIQSGTLKIHMVTHSDVRPFGCEVCDMRFTQSFTLKTHMLKQHDQLPTPRLKQNLKMRNRQSAIESDVKSDNYVGNVAGTHSSHSLDMISLHNGKQNSDRTTIDDRSNDDGKLTPETSETKSIFKADNDDRINNLNENVEEKLEMQQMEHIGAMEIRIDQVKVESEDAFENLSYSDDSQEEKQTFSHKQSSFKSARSPSLELQFSCDKCDQTFLTNADLKRHQRKHRERTQIICDECGKGFKHNYLLEMHKRTHSGQKPFKCDKCGATFAQRSNLNTHKRTHSKQKPFSCDVCSMGFTTKSSLKTHNLIHTNEKPFACDICGMRFTVKYKVKLHKNTHSGEKPYICELCGASFGQKSYLKKHMLVHSGIKAYSCDECPSKFSTKCALVQHKGYSHRGVDELSPRHRRKMQKMKLIAAGLLTNVS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00245621;
90% Identity
-
80% Identity
-