Basic Information

Insect: Bradysia coprophila
Gene Symbol: PZF1
Assembly: GCA_014529535.1
Location: NW:5060053-5063426[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.38 16 6.0 0.3 1 23 21 43 21 43 0.87

2 14 2.8 1.2e+02 3.3 1.1 2 23 124 146 123 146 0.87

3 14 0.03 1.3 9.5 0.1 2 23 160 182 159 182 0.92

4 14 0.32 14 6.3 1.5 2 18 200 216 199 216 0.91

5 14 0.004 0.17 12.3 6.8 1 23 238 261 238 261 0.95

6 14 0.0077 0.33 11.4 0.3 2 21 267 286 266 287 0.93

7 14 0.019 0.81 10.1 0.3 1 23 333 355 333 355 0.96

8 14 0.0036 0.15 12.4 0.9 1 23 361 384 361 384 0.94

9 14 7.6e-07 3.3e-05 24.0 0.8 1 23 390 412 390 412 0.97

10 14 0.00044 0.019 15.3 4.7 2 23 419 441 419 441 0.97

11 14 1.3e-06 5.6e-05 23.2 1.8 1 23 447 469 447 469 0.99

12 14 0.00019 0.0081 16.4 0.3 2 23 475 496 474 496 0.97

13 14 3e-05 0.0013 18.9 0.2 2 23 503 524 502 524 0.95

14 14 2.6 1.1e+02 3.4 0.1 1 10 529 538 529 545 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.38	16	6.0	0.3	1	23	21	43	21	43	0.87
2	14	2.8	1.2e+02	3.3	1.1	2	23	124	146	123	146	0.87
3	14	0.03	1.3	9.5	0.1	2	23	160	182	159	182	0.92
4	14	0.32	14	6.3	1.5	2	18	200	216	199	216	0.91
5	14	0.004	0.17	12.3	6.8	1	23	238	261	238	261	0.95
6	14	0.0077	0.33	11.4	0.3	2	21	267	286	266	287	0.93
7	14	0.019	0.81	10.1	0.3	1	23	333	355	333	355	0.96
8	14	0.0036	0.15	12.4	0.9	1	23	361	384	361	384	0.94
9	14	7.6e-07	3.3e-05	24.0	0.8	1	23	390	412	390	412	0.97
10	14	0.00044	0.019	15.3	4.7	2	23	419	441	419	441	0.97
11	14	1.3e-06	5.6e-05	23.2	1.8	1	23	447	469	447	469	0.99
12	14	0.00019	0.0081	16.4	0.3	2	23	475	496	474	496	0.97
13	14	3e-05	0.0013	18.9	0.2	2	23	503	524	502	524	0.95
14	14	2.6	1.1e+02	3.4	0.1	1	10	529	538	529	545	0.87

Sequence Information

Coding Sequence: ATGGAAGCTGAAGTTAGCGAGTCTGGTAAAATTTATCGGAATGCAAGTGGCCTCTTCTGCTTTGTATGCGATCATTGTGGCAGTTATTTTGATAATGTCAACGAAACACTGGAACACATCGATGGTCATTTTACCGGTGGAACAATAATCACCGATGCAATTGGCTCAAATCAAACTTGTGCAATTGAAAACAAAGCAGAAAATTCGCTAGACTTCATTGCAATCAGTGATATTACCGCCGATCttcgGTCCAATTTACGCGTCAAAGATGAGAGCAAACAAAATGAGACCTGCGTTGAAGATTGGCTGGAACCAAGTGGTTCGACCGACTTTATGACAGATTCGATCATTGATCGAAAACGGTGCATCCACTGCTCCTACTGCGCGGAGCATTTTGCTAGTCGCCTATTTTTGGTACTACATTCCGAAATCTCTCATCCTAACCAACCAATTGAAGGGGAACAGACTGGTGATTTACAGTGCGAGGGATGCTCGATCGAATTCGATACACCTACTAAACTGGAAGGGCATTTCAATCAGCAGCATCCGACAGAAGTAGCCACAGACATTAAAGTAAATGACGCAGACGAATGCTCCGAGTGTAAATTTTGTCGTCGGTCGTTTAAGGCAAAACATCTGCTTAAGCGACTCCTACAAAGATCCACATGTAAAGACGAATTTTGCAAACCGACGCAAATTGGGGAATTTCCATTTTACTGCGACATCTGCGGCCACGGTTTTCGCCACAAGTTTCGCTTGATCCATCACATGACTCAACGGCATACCGGAAAGGAAGACAAGTGCAAATATTGCAATCAACGATACGTACTCGAAGCATCGCTGAGACGGCACGAAAATTCGGAATGTCTGCTACGACCGAATGCGGATGAAAATGGAATCGCTAAAGCCAACAATAAGAACGTTACATTGTCATCGGATGGGAATAAGTCATGGGACGGATACCGGGAGTCGAAAAATGTACAGCGCCCGAAAATGTTTAGCTGTGATCCTTGCCAGAAGTCTTACGATACACCCTACATTTTGAAGCAACACATTCTGTCCCACTCAAACTTGCGCgaatttaaatgtaatttgtGCGATTCCGCGTACAACACGAAACCAAGACTTCGCAGACATGTCATCTATAATCACACCGATCGTCCCACATTCGATTGCGAAGTTTGCGGCTGGAAGTTTCGCGAGAAGAATAATTTGAAGAGGCACTTGCGGCTGCACAATGGTGATTATCAGGCAGAGTGCCAACTTTGCGATAAGAAATTCACTGCCAATTGTCATTTGAAGTATCACATGAATACTGCACACAGTACGGAAACTCCATATCAGTGCGATCTTTGTGGAAAGTCCTTTAATTCAACCAGTAAAATGAATGCGCACCGACGGCGACACATCAAAGAAACGCTACCGTGTGACATTTGTGGCAAAATATTCGGCAGCAGGAATCGATTGTACGCCCACAAAAAGACACATACCGAGGAGCGGAATATCGTGTGCAAAGTGTGtggaaaaaattttaagactGCAGTGGTTTTGCGTCAGCATATGTACTTGCACAAAGGGAAAATCTTTTCCTGCAACTTCTGTCCGATGACATTCGGGATACCCATGTCATTGTcgttgaaaattgtttgtgaCGAGTATGGCGATTCCTAG
Protein Sequence: MEAEVSESGKIYRNASGLFCFVCDHCGSYFDNVNETLEHIDGHFTGGTIITDAIGSNQTCAIENKAENSLDFIAISDITADLRSNLRVKDESKQNETCVEDWLEPSGSTDFMTDSIIDRKRCIHCSYCAEHFASRLFLVLHSEISHPNQPIEGEQTGDLQCEGCSIEFDTPTKLEGHFNQQHPTEVATDIKVNDADECSECKFCRRSFKAKHLLKRLLQRSTCKDEFCKPTQIGEFPFYCDICGHGFRHKFRLIHHMTQRHTGKEDKCKYCNQRYVLEASLRRHENSECLLRPNADENGIAKANNKNVTLSSDGNKSWDGYRESKNVQRPKMFSCDPCQKSYDTPYILKQHILSHSNLREFKCNLCDSAYNTKPRLRRHVIYNHTDRPTFDCEVCGWKFREKNNLKRHLRLHNGDYQAECQLCDKKFTANCHLKYHMNTAHSTETPYQCDLCGKSFNSTSKMNAHRRRHIKETLPCDICGKIFGSRNRLYAHKKTHTEERNIVCKVCGKNFKTAVVLRQHMYLHKGKIFSCNFCPMTFGIPMSLSLKIVCDEYGDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -