Basic Information

Insect: Bradysia coprophila
Gene Symbol: ZNF219
Assembly: GCA_014529535.1
Location: NW:816822-823678[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 2e-06 8.6e-05 22.6 0.7 1 23 66 88 66 88 0.99

2 11 2e-05 0.00087 19.5 1.2 1 20 94 113 94 114 0.96

3 11 3e-05 0.0013 18.9 1.0 1 23 123 145 123 145 0.99

4 11 0.0083 0.36 11.3 1.4 1 23 151 173 151 173 0.97

5 11 0.00013 0.0058 16.9 0.6 3 23 181 201 181 201 0.98

6 11 0.0006 0.026 14.8 3.4 2 23 208 230 207 230 0.95

7 11 0.0021 0.092 13.1 3.4 1 23 236 256 236 256 0.98

8 11 5.9e-06 0.00025 21.2 0.2 1 23 262 284 262 284 0.97

9 11 0.00077 0.033 14.5 2.3 1 23 290 312 290 312 0.98

10 11 0.00051 0.022 15.1 0.7 1 23 318 342 318 342 0.94

11 11 0.0076 0.33 11.4 1.9 1 23 348 371 348 371 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	2e-06	8.6e-05	22.6	0.7	1	23	66	88	66	88	0.99
2	11	2e-05	0.00087	19.5	1.2	1	20	94	113	94	114	0.96
3	11	3e-05	0.0013	18.9	1.0	1	23	123	145	123	145	0.99
4	11	0.0083	0.36	11.3	1.4	1	23	151	173	151	173	0.97
5	11	0.00013	0.0058	16.9	0.6	3	23	181	201	181	201	0.98
6	11	0.0006	0.026	14.8	3.4	2	23	208	230	207	230	0.95
7	11	0.0021	0.092	13.1	3.4	1	23	236	256	236	256	0.98
8	11	5.9e-06	0.00025	21.2	0.2	1	23	262	284	262	284	0.97
9	11	0.00077	0.033	14.5	2.3	1	23	290	312	290	312	0.98
10	11	0.00051	0.022	15.1	0.7	1	23	318	342	318	342	0.94
11	11	0.0076	0.33	11.4	1.9	1	23	348	371	348	371	0.90

Sequence Information

Coding Sequence: atgaaaaaaacgaaaaccgaCAAAACTCAAACCAAATGTCAATTAACTCGTAAACGACAGTCATTGAGAACTAAAACCAATACAACGCTCAACAGCGAACAATCCGTATCGTCATCGAACGAACCAAATGCTAATGAGAACGCACAAAATTTGTCCAACGTTGTCGAAGACGTTGCCCGAAAACCACGGAAAAAATATCAGTGCGAAGTGTGCCAAAAAGAATTCGGCTACAGCAACGATTTGCGAAAACACTTGAGAATTCATTTGGACGAACGACCGTTTTCTTGTACGCAATGCGATAAAACATTTCGCCAGGCTGGGTGCCTTAAAAATCATATTGCGTGTCAACACGGCACAGACATTAGTTACACTTGTGATTACTGCACAAAATCGTTTCCTATCAAAGAGCGCCTTAGACTCCATTTGCGTATACACTCCGGTTTCAAGCCGTATCATTGCTTTATTTGTCTGAAAAAGTTTGCGAGGGGTGGTCAGGTTACTCAACATATGGTCTCACATGCAAATTCGAAAAAAGTTGGATGCTCGAAGTGTCCGGCAACATTTACAAATACGGCAAATTTACGAAGTCATCTGAAGGCTCACTATGGCATTAAGGATTGCTGTTGTGAAATTTGTGGGAAGACGTTTCTACGAATCGATGCGCTGAAGAAGCACATCAACAGCTACCataaaaatgtcaaatcaTTCACTTGTGGCATTTGCAAGCGATCGTTCAAAGGTCATTTAACACAGCATCTGCAAACACATGAACAACACAAAATCTACGCTTGTACCGTTTGCAATGCAACATTTGCCCAAAACTCTCAATTGAAGGTCCATTCAAGGGTTCATTCAGGAGAGCGTCCGTTCCGCTGTATGGTGTGCCTCAAGTCCTTTGGTCATTCGAGTGTGTTGAGATTACACGTCCGAAAACACACCGGAGAGAAGCCCTTCTCCTGCCCGATTTGCAACGAATCGACATTTTCTCAACTTCCCCACCTGAAAACACACATGCGTGCCATTCACAACAAGCTTGAATCGTACCTTTGCCGAACGTGTAATACGTTTTTCCGCACAAAAATAGAATTACAACAACACAACGACATGAAGCATCGCTCAATAGAAGATGAAGATCCGGAAAACAGCTACGACAGCCATGGACAGTACCTCGATACGACAACAACAGCTAGAGCCTTGACGCGTATTCGGCTGCTGGTGGCAGTACTGCTGAAGAGGATATCAACTCCACAACGATTGAAGCAATTGGGATTCGAGAAGCGGTTGATAGACAACGTCCTTATTTCTGCATTGAAAACGTCAGGTCAACCGTGTTGCGAAGATGATCAAACGGAAACGGAGAAACTACGAGCGAATGTGAGCCACTTTTTGAAGTGGACGGTGCcggaaaaattgatgaaagaCTACGAACGACAACGTAAAAGTGTTGATGAGGTTCTTGAAGAGTTAGcgatgaaaaatttcaatgggAAATGA
Protein Sequence: MKKTKTDKTQTKCQLTRKRQSLRTKTNTTLNSEQSVSSSNEPNANENAQNLSNVVEDVARKPRKKYQCEVCQKEFGYSNDLRKHLRIHLDERPFSCTQCDKTFRQAGCLKNHIACQHGTDISYTCDYCTKSFPIKERLRLHLRIHSGFKPYHCFICLKKFARGGQVTQHMVSHANSKKVGCSKCPATFTNTANLRSHLKAHYGIKDCCCEICGKTFLRIDALKKHINSYHKNVKSFTCGICKRSFKGHLTQHLQTHEQHKIYACTVCNATFAQNSQLKVHSRVHSGERPFRCMVCLKSFGHSSVLRLHVRKHTGEKPFSCPICNESTFSQLPHLKTHMRAIHNKLESYLCRTCNTFFRTKIELQQHNDMKHRSIEDEDPENSYDSHGQYLDTTTTARALTRIRLLVAVLLKRISTPQRLKQLGFEKRLIDNVLISALKTSGQPCCEDDQTETEKLRANVSHFLKWTVPEKLMKDYERQRKSVDEVLEELAMKNFNGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00246583;
90% Identity: iTF_00246583;
80% Identity: -