Bcop010466.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bradysia coprophila
Gene Symbol
ZFX
Assembly
GCA_014529535.1
Location
NW:4443076-4455979[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.1e-06 4.7e-05 23.5 1.0 2 23 199 220 198 220 0.97
2 16 2.1e-06 9.1e-05 22.6 0.9 1 21 241 261 241 262 0.94
3 16 0.0024 0.1 12.9 0.2 2 23 272 294 272 294 0.96
4 16 0.00047 0.02 15.2 2.8 1 23 300 322 300 322 0.97
5 16 2.5e-06 0.00011 22.3 1.7 1 23 328 351 328 351 0.97
6 16 0.24 10 6.7 6.5 1 23 356 378 356 378 0.96
7 16 0.001 0.044 14.1 7.7 1 23 384 406 384 406 0.99
8 16 2.9e-05 0.0012 19.0 2.9 1 23 412 434 412 434 0.96
9 16 1.3e-05 0.00055 20.1 0.3 1 23 440 462 440 462 0.98
10 16 3.1e-08 1.3e-06 28.3 2.1 1 23 468 490 468 490 0.99
11 16 0.00032 0.014 15.7 1.9 1 23 496 519 496 519 0.96
12 16 2.8e-05 0.0012 19.0 2.3 1 23 542 564 542 564 0.98
13 16 1.5e-05 0.00066 19.9 1.3 1 23 570 593 570 593 0.95
14 16 3.1e-05 0.0013 18.9 0.6 1 23 599 621 599 621 0.98
15 16 0.046 2 8.9 4.2 1 23 627 649 627 649 0.96
16 16 0.0077 0.33 11.3 1.0 1 23 655 677 655 677 0.98

Sequence Information

Coding Sequence
ATGGCCGTTGATAATTCAGAAACAACATTTATTCTACATGAAACATGCCGATTGTGTTTGCTGAACATCGACCAGCTCCACGGGATGCAATCGATTCCAATATTTACAGACCGTGATGACACTCCGGAAGCGATCCTAAATGAGttcaatttcttgaaattaaaGCTGGCCCAAAATGATGGACTTCCACAGCAAATATGTGatgaatgtttgaaaaatctgTTGAATATTCGTGCATTCCGTACGAATTGCGAACGATCTCAGGATGTTcttgaaaaattcttcaaaccCGCAAGTGAATCGACCACATCCGCGACCGTACCAATTAAACTGATTGCCGATCTGAGCGAATCAAATTTCTCAGACTTTGAATTCCTGAACATCGACAACGTCGAAGATAATGTCGAATACGAGATGAAAATCGAGGTGGTAGCTGTCGATGAATCAATAGTAACTGGTGAAATCGAATGCACCGACGAATCGAAGGAAAATTGTTCAGGTGACAGCGAACTGGTTGGCGAAGATACAGAAAACGTTGATGAAACTAGCAGTTGTATGTCTAGTGACAGTACGCACGATGATTCCGACAATATCGAGTGCAGCATCTGCGGAAAAATCTACAAACGAAAAGCTCACTTGTTAAGGCATCTGATGTCGCACAAGAACAAGACTGACAGTGGTGATAAAGTAAGTGATAGCGGAAAGGGTAGGCACTGCGTATTTGTGTGCAACAAATGTGGGAAGAGATTTTCGAAATCAAAGAATCTGCAAAATCATGTCAACGACGGAGGTTGTGTGAAAGAGGAGAATCCTCAGTGTCGATTCTGCAAAGAGACATTTTCGAGCATCGGCGATCTGGAGATACATCTGGAGAAAGTCCATCCACCGCATCGACCCCACATGTGTCCGATAtgcaaaaaaacttttcaaagtGTCTCGAACCGCAACACTCATCTGCAATCGCATAACAAAGATGACACGTACAAATGTAGCGACTGTGGGCAGGGATTCAAAAGCAAAGTTTATTTGAACAAGCACAAAAAGTCCGTGCATACACGGAACGAACACGATTGTCCACACTGTTCGATGAAATTCTTCAACACAACAAAGTTCGAGTATCATCTGAAGTCgcatgacgaaaataaaaAGTACAAATGCAAGTACTGTGACAAGTCGTTCCTGCAGCATCATCATTTGGCCAATCATGAACGAATCCACACAAATGTTCGGCCGTTTCTATGTAACATTTGTGGAAAAGACTTCAAACAAGAATGCAACTTTAAGCTCCATCTCAGAATTCATTCGGGATTGCGACCGTATGTGTGTTCAGTCTGTGGCAAAGATTTCATTCAGCGCGGATCATTTGTTATGCATATGAAACAGCATTCAGGGGTTCGACCCTATCAGTGCGAGCATTGCGGCAAGGATTTCATTCAAAAGTCATCGCTCACGGTTCATCTGCGCACCCACACCGGCGAACGTCCCTTCAAATGCGATTCGTGTGATCGAGCTTTCGTGCAGGCTCAACAGCTCAAATACCATCGCCATTCGGCACATGGCGGTCCGTCGTTAAGTAAAAAGGAACCACCACCGAAGCCGTCCAGTGACGGTCGAATCTATCCGTACTGTTGTTCACTGTGCAACAAAGGATTCAAATTGCCGTCGTCGTTGTCGTCCCATATGAAAATCCACAATGAGGAACGCAAGCACGTTTGTTCGCAGTGCGGAAATTCGTTTAAACGTGCCGAACATTTGCGAATTCATATCAACGGCGTCCATTTGAAGAAGAAACCTTATACGTGCGAATACTGCCCGAAAACGTTTGCCCAATCCGGCGATCGGAACATCCATCGACTGCGGCATACGCATGAGAAAAATCACCAGTGCACATACTGCATGAAAATGTTCAGGCTACCGAAAGCGTTACGAGCTCACTGCCGGATACACACCGGAGAGAGGCCATACACATGCGAATTTTGCCAAATGGACTTTATGACCTACACAGCCTTAGCCACACACACGATGAAACACGAAAATGTTCTATCAGCCGAAGCACCGAGCGTAAAAGATGAATTAAAAGCTGCGACTATACCATTGGGTATTATAACAGCATCGGATTCGAATTTGGTTCTGACATTGACCAACTGA
Protein Sequence
MAVDNSETTFILHETCRLCLLNIDQLHGMQSIPIFTDRDDTPEAILNEFNFLKLKLAQNDGLPQQICDECLKNLLNIRAFRTNCERSQDVLEKFFKPASESTTSATVPIKLIADLSESNFSDFEFLNIDNVEDNVEYEMKIEVVAVDESIVTGEIECTDESKENCSGDSELVGEDTENVDETSSCMSSDSTHDDSDNIECSICGKIYKRKAHLLRHLMSHKNKTDSGDKVSDSGKGRHCVFVCNKCGKRFSKSKNLQNHVNDGGCVKEENPQCRFCKETFSSIGDLEIHLEKVHPPHRPHMCPICKKTFQSVSNRNTHLQSHNKDDTYKCSDCGQGFKSKVYLNKHKKSVHTRNEHDCPHCSMKFFNTTKFEYHLKSHDENKKYKCKYCDKSFLQHHHLANHERIHTNVRPFLCNICGKDFKQECNFKLHLRIHSGLRPYVCSVCGKDFIQRGSFVMHMKQHSGVRPYQCEHCGKDFIQKSSLTVHLRTHTGERPFKCDSCDRAFVQAQQLKYHRHSAHGGPSLSKKEPPPKPSSDGRIYPYCCSLCNKGFKLPSSLSSHMKIHNEERKHVCSQCGNSFKRAEHLRIHINGVHLKKKPYTCEYCPKTFAQSGDRNIHRLRHTHEKNHQCTYCMKMFRLPKALRAHCRIHTGERPYTCEFCQMDFMTYTALATHTMKHENVLSAEAPSVKDELKAATIPLGIITASDSNLVLTLTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00246535;
90% Identity
iTF_00246535;
80% Identity
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