Basic Information

Insect: Bradysia coprophila
Gene Symbol: ZFX
Assembly: GCA_014529535.1
Location: NW:23289-26910[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 1.2e-06 5.1e-05 23.4 2.2 1 23 93 115 93 115 0.96

2 16 0.0001 0.0044 17.2 0.6 1 23 121 143 121 143 0.98

3 16 0.0043 0.19 12.1 4.9 1 23 155 177 155 177 0.98

4 16 3.3e-06 0.00014 21.9 0.4 2 23 191 212 191 212 0.97

5 16 1.2e-08 5.3e-07 29.6 1.1 1 23 219 241 219 241 0.98

6 16 0.00018 0.008 16.5 1.2 1 23 247 269 247 269 0.98

7 16 3e-05 0.0013 18.9 4.3 1 23 275 297 275 297 0.99

8 16 8.3e-05 0.0036 17.5 3.0 1 23 314 336 314 336 0.98

9 16 2.3e-06 9.9e-05 22.4 4.2 1 23 342 364 342 364 0.99

10 16 0.00031 0.014 15.7 1.1 1 23 370 392 370 392 0.97

11 16 0.00012 0.005 17.1 2.6 1 23 399 421 399 421 0.98

12 16 3.1e-06 0.00013 22.0 1.8 1 23 432 454 432 454 0.98

13 16 7.8e-05 0.0034 17.6 0.3 5 23 462 480 459 480 0.94

14 16 0.0027 0.12 12.8 4.6 1 23 486 508 486 508 0.97

15 16 1.3e-05 0.00056 20.1 0.6 1 23 514 536 514 536 0.97

16 16 0.0013 0.058 13.7 0.2 1 23 540 563 540 563 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	1.2e-06	5.1e-05	23.4	2.2	1	23	93	115	93	115	0.96
2	16	0.0001	0.0044	17.2	0.6	1	23	121	143	121	143	0.98
3	16	0.0043	0.19	12.1	4.9	1	23	155	177	155	177	0.98
4	16	3.3e-06	0.00014	21.9	0.4	2	23	191	212	191	212	0.97
5	16	1.2e-08	5.3e-07	29.6	1.1	1	23	219	241	219	241	0.98
6	16	0.00018	0.008	16.5	1.2	1	23	247	269	247	269	0.98
7	16	3e-05	0.0013	18.9	4.3	1	23	275	297	275	297	0.99
8	16	8.3e-05	0.0036	17.5	3.0	1	23	314	336	314	336	0.98
9	16	2.3e-06	9.9e-05	22.4	4.2	1	23	342	364	342	364	0.99
10	16	0.00031	0.014	15.7	1.1	1	23	370	392	370	392	0.97
11	16	0.00012	0.005	17.1	2.6	1	23	399	421	399	421	0.98
12	16	3.1e-06	0.00013	22.0	1.8	1	23	432	454	432	454	0.98
13	16	7.8e-05	0.0034	17.6	0.3	5	23	462	480	459	480	0.94
14	16	0.0027	0.12	12.8	4.6	1	23	486	508	486	508	0.97
15	16	1.3e-05	0.00056	20.1	0.6	1	23	514	536	514	536	0.97
16	16	0.0013	0.058	13.7	0.2	1	23	540	563	540	563	0.96

Sequence Information

Coding Sequence: ATGGAACCACTGCAGGAAGGTCTAGTGGAAGAAATATGGATAAAACCCGAGCCAACTGATGACTGTTTACCCACCACTGACTGTCGCATAAAAAGTGAAGAGGAGGAAATCGATATCGCTGAAATTGACCCATTCACTGCAACGACTACGTTCACCATCCACACTGATGTCAGTCCAGAGCTATACGAGCAAGAAGCTTTGATTATTAAGTCGGAATTCGGGTTCGACAATGACAACGACAATGACGAATCCACGGAGCACACAACGTCACACATTCATGATTGCAAGGAATGCGGCAAGGTATTTTCGATCAAATCCAGTCTCAGCAGACATCTGAAAATGCATTCAGGTGAAAAACCCTTCGAATGCGACATTTGTGGAATGCGATTTGCACAAAagGCCCACGTAAAGCCGCACCAAATGACACATACTGAGCAAAAATTCGTTCTAGGTGAGAAACCCTTCGAATGCAACCAATGCGGCATCCACTTTGCCTACAAAAAGTCGTTGCAATGTCACCTGCAAACCCACAGCCGTGAAGGAACCTGCGAAAAACCGAACCCATCAAATGAATGCGACGAATGCGGGAAAACGTTTGCCAGACGGGCTACGCTAAAGATTCACAAACTGATGCACGCTGGTGAGGCGCCCGTATTTTCGTGCACCGAGTGCGGCAAATCATTCCCACGAAAGTCAAGCCTGACCAGACATCTACTGATGCATTCCGGTGAAAAACCCTTCGAATGCGACATTTGTGGAATGCGATTTGCACAGAAGGGACACGTTAAGCCACATAGGAGAAAACACACTGGTGAAAAACCGTTTGAATGCGATCATTGCGACATgaattttatgtacaaaaaatcgttgaaacaACACTTGAGAACTCATCGCGATCTGATAGCCGGCTATGAAGAAGAGATCGTCGTACGTAAAATCTACGAATGCGACGAATGCGAAGAGACATTCCATCGCCGCGATAATTTCAAATGGCACAAATTGAAGCACCTTGGCCACGTTCCCTTCCAATGTGACCAATGCGGAAAGCAATTTTTCCGGAATGACCATCTTGTCCGCCATAAGCGGATGCATTCAGGTGAAAAACCGTTCGAATGCGAAATTTGTGGAATGCGATTTTCACAGAAGGCCCACGTCAAACCGCACAAATTGACCCACACACCATCCGATCGACCATTTCCGTGCGACGAATGCGACAAGAGATTCGTGTGCCAATCGGCATTGACAAAGCACAAGAAAATGCACGAAACAAGTTTGACTGTGGACGATTGGTCATTTTATTGCGTCGAATGTGACACCAAATTCACCAGCCAATCTGAACTGAACAAACACAAGCTAACGCACGGCGAGCTACCGTTCAAATGCGAATGCGGAAAGGCATTTCCGCGCAAGTCAAGTCTCATCCGACACGAACTCGTTCATTCAGGTGAAAAGCCCTTCGAATGTGATCTGTGCGGTCAGACATTTAAACAGAAACATCACGTCAAACCGCACAAATTGACCCACCGAGACGATCTGATTTTCGAATGTGACGAATGCGATAAGAAATTTGCTCGTGATTCGGCGCTCAGCAAACACAAACAGCTGCACATAGCAATATACCGATGCAGTCTGTGTAATGCTACCTTCGATCAGGAACAGCCATTGGTGCAGCATATGAAGGATATTCATCTGTGA
Protein Sequence: MEPLQEGLVEEIWIKPEPTDDCLPTTDCRIKSEEEEIDIAEIDPFTATTTFTIHTDVSPELYEQEALIIKSEFGFDNDNDNDESTEHTTSHIHDCKECGKVFSIKSSLSRHLKMHSGEKPFECDICGMRFAQKAHVKPHQMTHTEQKFVLGEKPFECNQCGIHFAYKKSLQCHLQTHSREGTCEKPNPSNECDECGKTFARRATLKIHKLMHAGEAPVFSCTECGKSFPRKSSLTRHLLMHSGEKPFECDICGMRFAQKGHVKPHRRKHTGEKPFECDHCDMNFMYKKSLKQHLRTHRDLIAGYEEEIVVRKIYECDECEETFHRRDNFKWHKLKHLGHVPFQCDQCGKQFFRNDHLVRHKRMHSGEKPFECEICGMRFSQKAHVKPHKLTHTPSDRPFPCDECDKRFVCQSALTKHKKMHETSLTVDDWSFYCVECDTKFTSQSELNKHKLTHGELPFKCECGKAFPRKSSLIRHELVHSGEKPFECDLCGQTFKQKHHVKPHKLTHRDDLIFECDECDKKFARDSALSKHKQLHIAIYRCSLCNATFDQEQPLVQHMKDIHL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00246528;
90% Identity: iTF_00246528;
80% Identity: -