Basic Information

Gene Symbol
-
Assembly
GCA_958510825.1
Location
OY294045.1:2105009-2105950[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00022 0.013 16.9 2.2 1 23 28 50 28 50 0.91
2 10 0.006 0.34 12.4 2.0 1 23 54 77 54 77 0.95
3 10 0.065 3.7 9.1 3.3 1 23 82 104 82 104 0.98
4 10 0.055 3.1 9.3 2.3 2 23 111 133 110 133 0.94
5 10 0.0012 0.066 14.6 2.1 1 23 138 160 138 160 0.98
6 10 2.1 1.2e+02 4.3 0.2 2 23 171 193 170 193 0.74
7 10 0.0056 0.32 12.5 3.0 1 23 198 220 198 220 0.96
8 10 5.1e-06 0.00029 22.0 0.4 3 23 228 248 227 248 0.99
9 10 2.9e-05 0.0016 19.7 1.9 1 23 254 276 254 276 0.97
10 10 0.0027 0.15 13.5 0.4 1 23 282 305 282 305 0.97

Sequence Information

Coding Sequence
atgtatatttttagattatttttgacaattaacaaaaaactgttCGAGTACAAAACCTCCACCAATAATAGTAAAAGGATATTCCACTGCCTGAACTGTCCTGAAACGTTTAAAACCAAAAGGGCACTAAGAAGACATCTTCCCAcacataaaatagtttattcCTGTGACTTGTGTTCCAAAACCTTCCAGCGTTTCATCACCCTTTTGCAACACAAAGAAAGAACTCACGTCAAGCGTGAATACCCTTGCGAAATATGCAGCAAGGTCTTGCACAGTGTCCATGGCTACAAAATGCATAAAAGAAGGCATGAAGGAGCATACCTGGTAAAATGCCTAACCTGCGATATCGGCTTTTTTTCTAAATGTCAGTATAAACTACACATGGGCTCTCGGCATGGTAAAAGCGAGTTTGTTTGTGAAGTTTGTAGTCGACATTGCTATGACAACACAGCTTTAGCAAATCACTTGTTAACTCATGAGGAAGGCTACAAAGAAAAACACAGAGTGCAATGCAAAATTTGCGATAAGTGgttaatttctgaaaaaatattgcGTGTGCATATCTACAAAATGCACCAACAAACTAAATTTATGTGCCACACGTGCGGAAAAGAGCTTAATAGCAAGAACGCTTTACACACCCATAACTTAATCCATCAAGGGTTAAAACCGAACTTGTGTTCTTATTGTGGAAGAGGGTTTGCCGATAAGAACACCCTAAGAGGCCATATTCGCACTCACACGGGAGAAAAACCGTATTGTTGCAACACGTGCGGAAGGAGGTTTGCGCAACCTGGTGCATTCAAGATTCACAAAAGATTGCACTCTGGTGAAAAACCGTTTTCGTGCGATCTTTGTAAAGATAGTTTTGTATCGAGTAGTGTGTTGAACGCACACGTGAAAAGTAAACATAAGGTCATGAATTTTCATTTAGATTAa
Protein Sequence
MYIFRLFLTINKKLFEYKTSTNNSKRIFHCLNCPETFKTKRALRRHLPTHKIVYSCDLCSKTFQRFITLLQHKERTHVKREYPCEICSKVLHSVHGYKMHKRRHEGAYLVKCLTCDIGFFSKCQYKLHMGSRHGKSEFVCEVCSRHCYDNTALANHLLTHEEGYKEKHRVQCKICDKWLISEKILRVHIYKMHQQTKFMCHTCGKELNSKNALHTHNLIHQGLKPNLCSYCGRGFADKNTLRGHIRTHTGEKPYCCNTCGRRFAQPGAFKIHKRLHSGEKPFSCDLCKDSFVSSSVLNAHVKSKHKVMNFHLD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-