Basic Information

Insect: Brachyptera risi
Gene Symbol: lola
Assembly: GCA_964007535.1
Location: OZ023333.1:10363770-10375155[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.001 0.09 14.3 0.3 2 21 29 48 28 49 0.94

2 14 9.8e-06 0.00086 20.7 2.1 2 21 56 75 55 76 0.93

3 14 0.38 34 6.2 0.7 2 12 83 93 82 95 0.89

4 14 0.00035 0.031 15.8 0.1 2 21 95 114 94 115 0.95

5 14 0.0057 0.5 12.0 0.1 3 20 123 140 122 142 0.93

6 14 0.00011 0.0094 17.4 0.3 2 21 149 168 148 169 0.93

7 14 0.00071 0.063 14.8 2.0 1 21 194 216 194 217 0.96

8 14 0.00025 0.023 16.2 0.1 1 21 253 273 253 274 0.95

9 14 0.12 11 7.8 5.8 2 23 283 305 282 305 0.94

10 14 0.13 11 7.7 1.6 1 21 335 355 335 356 0.95

11 14 0.00027 0.024 16.1 1.0 1 23 364 387 364 387 0.94

12 14 0.016 1.4 10.6 1.5 1 21 394 414 394 415 0.93

13 14 0.01 0.9 11.2 3.8 1 21 431 451 431 452 0.95

14 14 0.00015 0.013 17.0 2.4 1 23 460 483 460 483 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.001	0.09	14.3	0.3	2	21	29	48	28	49	0.94
2	14	9.8e-06	0.00086	20.7	2.1	2	21	56	75	55	76	0.93
3	14	0.38	34	6.2	0.7	2	12	83	93	82	95	0.89
4	14	0.00035	0.031	15.8	0.1	2	21	95	114	94	115	0.95
5	14	0.0057	0.5	12.0	0.1	3	20	123	140	122	142	0.93
6	14	0.00011	0.0094	17.4	0.3	2	21	149	168	148	169	0.93
7	14	0.00071	0.063	14.8	2.0	1	21	194	216	194	217	0.96
8	14	0.00025	0.023	16.2	0.1	1	21	253	273	253	274	0.95
9	14	0.12	11	7.8	5.8	2	23	283	305	282	305	0.94
10	14	0.13	11	7.7	1.6	1	21	335	355	335	356	0.95
11	14	0.00027	0.024	16.1	1.0	1	23	364	387	364	387	0.94
12	14	0.016	1.4	10.6	1.5	1	21	394	414	394	415	0.93
13	14	0.01	0.9	11.2	3.8	1	21	431	451	431	452	0.95
14	14	0.00015	0.013	17.0	2.4	1	23	460	483	460	483	0.97

Sequence Information

Coding Sequence: ATGCCACCTGATATTAGCCCGACCGTCACTCACCAGCGCACTGCACGGCGCTACGTTGAGAGTCGCGAGTCGGATAAAATCTGGCCTTGTACGAGTTGCAACAAACGGTTCGGTACGAAGGGTGGTCTTGCCAGACATGTAAGGCACGAATGCGGCAAGAAACTGCAGTGTCCCAAGTGTAACAAGCCCTTCAAGCATAAAACAAATCTGACTACTCACACTAATTATGAATGTGGTAAAGAAATACATTGTCCCAAGTGCAACAAGCATTTTGCGCGCGTGCAATGCCCCGCATGTGCTAAGGTCTTCAAGCGACCGAAACAGCTGAGTGAACACATTAGGAACGATTGCGGACAAGTTCGTCATTGTCCGACTTGCGTCAAACAATTCTCGTCCAAAGCAATGCTGATGGTGCATGTCCATCACGAGTGTGGCAAAAGACTTCAATGCTCGACGTGTAATAAGTTATTCTCGCGGAAAGCACAATTAACAGCTCATGTAAATTACGAGTGTGGCGTAATGGTCTGGCCTCCACCCCGTACCGCGACTGACGTCGGTGAACTGGTCGCAGGACTTCGCTTCCAATGTCCGACGCCCAACTGCACCAAGAGCTACAAGGAAAAGAGGCATTTGAACGCTCACTTGAAGCACGACTGCGGAAAACTATTGATTTGTCCAGGATATATGCTCAATGTGTTACGGCTTCATGGGTTAAACACTACCTGGCCATTACACTCCTACAACAACTCGAGTCGATATCCTTGTTCAGCATGCGACAAAGATTATTCCCGCAAAGACGCTCTGATCCGACATGTGAAGTATGAGTGTGGGAAAGAGCCTCAAGTCCAGTGTCCGCACTGCGAGTACCGCACCAATCACAAGTGCAACATGAAGACACACGTGATGGCTCGACACCCATTAGAGTGCGTTCATAACGATCACAGTCTGTCGTCATGGTTTCCAGTCGTTTGCCTTGCTGAGGGCGTGACGTCGCCTGCAAGGTTCCAGTGCCCCTCGTGCAGTCGTAGCTACTCGTGCAAAGGTCCGCTCACCACGCACATCAAGTTTGAGTGTGGCAAAGAGCCACAGTTTGCTTGTCCGTATTGTCCGTACCGCGCCAAACAGAAGGGCAACCTCAAGATACATCTGCTTCATCGACATAAAAACATGAAACTAGAGCATAACTGCTCAGCTTGTGGCCGACTATACAAGCAAAAATACAGTCTTGCCAACCACGTCAGACATGAGTGTGTCGATGGTTTTGTTATGCGCCGTTTCAACTTGTATCCATTTAAATGTCTCGTCTGCCTTCGGAGTTACAAACATCGTCAGAACTTGATCAATCACCACAAGTATGAGTGTGGTAAAGATCCACAATTCCAATGTCCGCAGTGTGATTACCGTGCCAAACTCAAAGGCAACCTCAAGCACCACATTAGGAACAAGCACAGTCTGAAGTGA
Protein Sequence: MPPDISPTVTHQRTARRYVESRESDKIWPCTSCNKRFGTKGGLARHVRHECGKKLQCPKCNKPFKHKTNLTTHTNYECGKEIHCPKCNKHFARVQCPACAKVFKRPKQLSEHIRNDCGQVRHCPTCVKQFSSKAMLMVHVHHECGKRLQCSTCNKLFSRKAQLTAHVNYECGVMVWPPPRTATDVGELVAGLRFQCPTPNCTKSYKEKRHLNAHLKHDCGKLLICPGYMLNVLRLHGLNTTWPLHSYNNSSRYPCSACDKDYSRKDALIRHVKYECGKEPQVQCPHCEYRTNHKCNMKTHVMARHPLECVHNDHSLSSWFPVVCLAEGVTSPARFQCPSCSRSYSCKGPLTTHIKFECGKEPQFACPYCPYRAKQKGNLKIHLLHRHKNMKLEHNCSACGRLYKQKYSLANHVRHECVDGFVMRRFNLYPFKCLVCLRSYKHRQNLINHHKYECGKDPQFQCPQCDYRAKLKGNLKHHIRNKHSLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -