Basic Information

Gene Symbol
ZNF341
Assembly
GCA_964007535.1
Location
OZ023328.1:5778809-5795172[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.017 1.5 10.5 1.4 2 23 48 69 47 69 0.94
2 15 3.2e-06 0.00028 22.2 1.0 2 23 169 190 168 190 0.97
3 15 2.1e-07 1.9e-05 25.9 0.6 1 23 196 218 196 218 0.98
4 15 4.1e-05 0.0037 18.7 1.7 1 23 253 275 253 275 0.98
5 15 0.14 12 7.6 0.5 5 23 287 305 281 305 0.88
6 15 5.8e-05 0.0052 18.3 0.7 1 23 311 333 311 333 0.98
7 15 0.018 1.6 10.4 1.0 1 22 347 368 347 371 0.90
8 15 0.0047 0.41 12.3 3.8 1 23 373 395 373 395 0.91
9 15 3.9e-05 0.0035 18.8 0.3 1 23 401 423 401 423 0.96
10 15 2.9e-05 0.0026 19.2 1.1 1 23 429 451 429 451 0.98
11 15 3.5 3.1e+02 3.2 0.3 1 16 481 501 481 503 0.91
12 15 6.9 6.1e+02 2.3 0.3 1 16 524 544 524 546 0.88
13 15 0.001 0.089 14.4 2.2 1 23 549 576 549 576 0.97
14 15 0.11 9.7 8.0 0.0 2 17 583 598 582 599 0.91
15 15 6.9 6.1e+02 2.3 0.8 1 19 612 630 612 633 0.90

Sequence Information

Coding Sequence
ATGTCTCAGTTGATTTTTGACGGGCTTGGTGTGTCTTTGGACAGCCAGACTGTTCAATCGCTACTTGAGTCGCAAGGCTTATCCAGTGAAGTGTCATCGTTGGGAACATCCTCCATCTTGTTTGACGAAGAAGATTTGATACAGTGCGGAAAATGCAAGAAGCAATTCAACTCGTTGACGTTGTTCATGAGTCACAAAGAAGAGCACAAGATGGGTCTGTTGTACAGCCGTCTGCAGTCGGGCATCGACGACCAGCTGTCGACCAATCAGGTGTCCAAGTTCCAACTCCAGACGCTGGACTCAGACTCGCCAATCATCGTCCAAGACGGGACGGACATCTTGTCGTTCAGTATCGACCAGAACGGAACGTTCATCAGCGCGTCCGGTGAGAGCATCGGATCGTTGAGCCAACCACTCATCCTCGCATCGGAGCTTGAGGACGGCGCGGACATGCTGGTCAAGGGGGAGGAGCCGCAGGAGGGCGAGGCCAAGGGCGAGAAGCTCAAGTGCGACTACTGCAACAAGGTGTTTGCCAAGAACTTCGACCTTCAACAGCACGTGCGCAGTCACACTGGCGAGAAGCCCTTCCAGTGCGTGGTTTGCGGTCGCGCCTTCTCTCAGAAGTCAAACGTCAAGAAGCACATGGTCACGCACAAGGTCTGGCCGGACGGCTTGTCCCGGACGCTACCAAAGGACCCGCTGCTGCGTCTGACGGAAGACACGACGAGCGAGGAGACGGTGATCGTTGACCGGTCGTACGTGTGCCAGTACTGCGCGACCCCGTACAAGTCGTACTACGAGCTGAAGAAGCACATGAAGAGTCACGTGGGCCGCAAGGTGTACAAGTGCATACAGCAGGGCTGCTCGGAGACGTTTGACGAGCTGGACGAGTTCCTGCGGCACACTCGTCAGCACCCTGACGACGTGGCGTACCGCTGTCACGTGTGCGGCAAGCAGTTCCCGACGCTGGCCGACCTCGGCCTGCACCAGTACAGTCACAGCGCGGCGCCCAGCAAGGCACACAAGAAGACAAAGTACTTCCGCTGTGTCCAGTGCAAGAGTCGCTTCGTGTCTCCGGAGGCCCTGGAGCACCACAAGGCCACCACTAGCCACCGTTACGCCTGCTCGCACTGCGGCAAGGTGTTCTCGTGCGAGCGGTACCTGCGTCGCCACCTGCCCACGCACGGCACCGCACACGCGTTTGTCTGCCCGTCGTGCGGCAAGGGCTTCCGCACCGAGCAGTACCTCAACACGCACCGTGTCATCCACTCGAGCGAGAAGCCGTTCACCTGCGAGCACTGCCCGTCGGCGTTCAACCGCAAGGACAAGCTCGCACGACACCTGCTCATACACCAGCCGACCAAGCGCTTCAAATGCCCGTTCAAGACTCATCTCGGCTGCCTCAAGGAGTTCAACAgacaagGAGTTCAACAgacaagCTTCAAGTGCCCATTCAAGACTCACCTCGGCTGCGTCAAGGAGTTCAACAcacaaggtaagctggtggttacACGCTTCAAGTGCCCGTTCAAGACTCACCTCGGCTGTCTCAAGCTGGTGGTTACACGCTTTGAGTGCCCATTCAAGACTCACTTTGGCTGCGTCAAGGAGTTCAACAcacaaggtaagctggtggttacACGCTTCAAATGCCCATTCAAGACTCACCTCGGCTGCCTCAAGGAGTTCAACAgacaagACAAGCTGAAGGTACACCTGCTGACCCACAGCAGCCAGAAGCAGATCCCGTGTGGCTCGTGCGACCGTGCCTTCGTGCGCTCCTCTCTGCTGCGCTCTCCCAAGAAGGTCCACCGCAAGCCGGACGCGGGTCGGTACGCTTGCACTCGCTGCGGGGCGGCGCACAAGACCGCCGCCCTGCTTCACGCACACAGCTGCTCGTACCCCTCGTCGCGGCGAGGACGCAACAAGCGGCGCGCCGTCACCCCCGACAACGTGCCCACCATCGAGATCATCGTGATGCCCGTATCGCGGACCGGCGGACAGTCGGCTGACTCGTCAGGCATGTACCAGGTGACGTTCCCGACGGCCAATCAGGGAGAGGACCAGGAAGTACCCGTCTGA
Protein Sequence
MSQLIFDGLGVSLDSQTVQSLLESQGLSSEVSSLGTSSILFDEEDLIQCGKCKKQFNSLTLFMSHKEEHKMGLLYSRLQSGIDDQLSTNQVSKFQLQTLDSDSPIIVQDGTDILSFSIDQNGTFISASGESIGSLSQPLILASELEDGADMLVKGEEPQEGEAKGEKLKCDYCNKVFAKNFDLQQHVRSHTGEKPFQCVVCGRAFSQKSNVKKHMVTHKVWPDGLSRTLPKDPLLRLTEDTTSEETVIVDRSYVCQYCATPYKSYYELKKHMKSHVGRKVYKCIQQGCSETFDELDEFLRHTRQHPDDVAYRCHVCGKQFPTLADLGLHQYSHSAAPSKAHKKTKYFRCVQCKSRFVSPEALEHHKATTSHRYACSHCGKVFSCERYLRRHLPTHGTAHAFVCPSCGKGFRTEQYLNTHRVIHSSEKPFTCEHCPSAFNRKDKLARHLLIHQPTKRFKCPFKTHLGCLKEFNRQGVQQTSFKCPFKTHLGCVKEFNTQGKLVVTRFKCPFKTHLGCLKLVVTRFECPFKTHFGCVKEFNTQGKLVVTRFKCPFKTHLGCLKEFNRQDKLKVHLLTHSSQKQIPCGSCDRAFVRSSLLRSPKKVHRKPDAGRYACTRCGAAHKTAALLHAHSCSYPSSRRGRNKRRAVTPDNVPTIEIIVMPVSRTGGQSADSSGMYQVTFPTANQGEDQEVPV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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